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■ Abbreviation / Long Form : PKG / protein kinase G

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Total Number of Papers: 616
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Abbreviation:   PKG  (>> Co-occurring Abbreviation)
Long Form:   protein kinase G
 Abbreviation Variation
 Long Form Variation
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No. Year Title Co-occurring Abbreviation
2019 Activation of cGMP/PKG/p65 signaling associated with PDE5-Is downregulates CCL5 secretion by CD8 + T cells in benign prostatic hyperplasia. BECs, BPH, cGMP, HFD, PDE5-Is
2019 Angiotensin-(1-7) induced vascular relaxation in spontaneously hypertensive rats. Ang, CA, MA, NO, PA, SHR, WKY
2019 B-type natriuretic peptide attenuates endoplasmic reticulum stress in H9c2 cardiomyocytes underwent hypoxia/reoxygenation injury under high glucose/high fat conditions. BNP, CK, eIF2alpha, ER, HG/HF, LDH, PKR, TUDCA
2019 Effects of tetrahydrobiopterin combined with nebivolol on cardiac diastolic function in SHRs. 3-NT, cGMP, DHE, eNOS, NO, PLN, ROS, SERCA2a, SHRs
2019 p38 mitogen activated protein kinase mediates cardiac Na+/H+ exchanger inhibition induced by Sildenafil. p38 MAPK
2019 PKC and PKN in heart disease. PKA, PKC, PKN, S6K
2019 PKG1alpha oxidation negatively regulates food seeking behaviour and reward. cGMP, KI, VTA, WT
2019 Sacubitril/Valsartan Decreases Cardiac Fibrosis in Left Ventricle Pressure Overload by Restoring PKG Signaling in Cardiac Fibroblasts. CFs, HF, SAC, VAL
2019 Signalling pathways involved in p47phox -dependent reactive oxygen species in platelets of endotoxemic rats. c-Src, LPS, PI3K, PKC, ROS
10  2019 The Dopamine D1 Receptor and Angiotensin II Type-2 Receptor are Required for Inhibition of Sodium Transport Through a Protein Phosphatase 2A Pathway. PKA, PP2A
11  2019 The vasodilatory effect of the antidiabetic drug linagliptin via inhibition of Rho-associated protein kinase in aortic smooth muscle. PKA
12  2019 TMPRSS2-ERG activates NO-cGMP signaling in prostate cancer cells. NO, PCa, sGC
13  2019 Vanillic acid in Panax ginseng root extract inhibits melanogenesis in B16F10 cells via inhibition of the NO/PKG signaling pathway. CREB, GC, GRE, MITF, NO
14  2019 Vasodilatory effect of kaempferol-7-O-alpha-L-rhamnopyranoside via NO-cGMP-PKG signaling. cGMP, HUVECs, KR, L-NAME, MB, MLC, NOS, ODQ, PE, PKC
15  2018 Activation of Protein Kinase G After Repeated Cocaine Administration Is Necessary for the Phosphorylation of alpha-Amino-3-Hydroxy-5-Methyl-4-Isoxazolepropionic Acid Receptor GluA1 at Serine 831 in the Rat Nucleus Accumbens. AMPA, cGMP, GluA1-S831, i.p, NAc
16  2018 beta3-adrenergic receptor activation induces TGFbeta1 expression in cardiomyocytes via the PKG/JNK/c-Jun pathway. beta3-ARs, JNK, TGF-beta1
17  2018 Characterizing the role of atrial natriuretic peptide signaling in the development of embryonic ventricular conduction system. ANP, CMs, CPCs, Cx40, HCN4, VCS
18  2018 Compartmentalized cyclic nucleotides have opposing effects on regulation of hypertrophic phospholipase Cepsilon signaling in cardiac myocytes. ANF, beta-AR, Epac, ET-1, PDE, PI4P, PKA, PLCepsilon
19  2018 Control of cardiovascular responses to stress by CRF in the bed nucleus of stria terminalis is mediated by local NMDA/nNOS/sGC/PKG signaling. BNST, CRF, nNOS, NO, NPLA, sGC
20  2018 Cyclic nucleotide signaling changes associated with normal aging and age-related diseases of the brain. AD, ANP, BNP, cAMP, cGMP, CREB, Epac, HCNs, HD, PDEs, PKA
21  2018 Effects of Estradiol and Progesterone-Induced Intracellular Calcium Fluxes on Toxoplasma gondii Gliding, Microneme Secretion, and Egress. IC, NO, PI-PLC, ROS
22  2018 Effects of the NO/soluble guanylate cyclase/cGMP system on the functions of human platelets. PKA, sGC
23  2018 egl-4 modulates electroconvulsive seizure duration in C. elegans. ---
24  2018 Endothelium-derived hyperpolarizing factor and protein kinase G Ialpha activation: H2O2 versus S-nitrosothiols. EDHFs, sGC
25  2018 Epistasis studies reveal redundancy among calcium-dependent protein kinases in motility and invasion of malaria parasites. CDPK
26  2018 Establishing a Split Luciferase Assay for Proteinkinase G (PKG) Interaction Studies. cGMP, PCA, PPI, RGS2
27  2018 Identification of a soluble guanylate cyclase in RBCs: preserved activity in patients with coronary artery disease. CAD, KO, PDE, RBCs, sGC
28  2018 Identification of dual mechanisms mediating 5-hydroxytryptamine receptor 1F-induced mitochondrial biogenesis. 5-HT1F, cGMP, eNOS, FOXO3a, MB, PGC-1alpha
29  2018 KMUP-1, a GPCR Modulator, Attenuates Triglyceride Accumulation Involved MAPKs/Akt/PPARgamma and PKA/PKG/HSL Signaling in 3T3-L1 Preadipocytes. GPCRs, HSL, ORO, p-HSL, PDEs, PKA, TG
30  2018 Nitric oxide augments single persistent Na+ channel currents via the cGMP/PKG signaling pathway in Kenyon cells isolated from cricket mushroom bodies. NO
31  2018 Nitric Oxide Generated by Tumor-Associated Macrophages Is Responsible for Cancer Resistance to Cisplatin and Correlated With Syntaxin 4 and Acid Sphingomyelinase Inhibition. ASMase, CDDP, iNOS, NO, synt4, TAMs
32  2018 Nitric oxide induces epidermal stem cell de-adhesion by targeting integrin beta1 and Talin via the cGMP signalling pathway. BrdU, ESCs, LRCs, NO, sGC, SNAP
33  2018 Nitric oxide-cGMP-PKG signaling in the bed nucleus of the stria terminalis modulates the cardiovascular responses to stress in male rats. BNST, L-NAME, nNOS, NPLA, sGC
34  2018 Particulate Guanylyl Cyclase A/cGMP Signaling Pathway in the Kidney: Physiologic and Therapeutic Indications. AKI, ANP, BNP, cGMP, Col-1, GFR, PDEs, pGC-A, TGF-beta, URO
35  2018 Phosphodiesterase inhibition and modulation of corticostriatal and hippocampal circuits: Clinical overview and translational considerations. cAMP, cGMP, CREB, DARPP-32, PDE inhibitors, PKA
36  2018 Phosphorylated vasodilator-stimulated phosphoprotein (P-VASPSer239) in platelets is increased by nitrite and partially deoxygenated erythrocytes. NO, P-VASPSer239, PKA, PRP
37  2018 Phosphorylation of protein kinase A (PKA) regulatory subunit RIalpha by protein kinase G (PKG) primes PKA for catalytic activity in cells. PKA
38  2018 PKG-Dependent Cell Death in 661W Cone Photoreceptor-like Cell Cultures (Experimental Study). ---
39  2018 Prevention of PKG-1alpha Oxidation Suppresses Antihypertrophic/Antifibrotic Effects From PDE5 Inhibition but not sGC Stimulation. ---
40  2018 Protein Kinase G Activation Reverses Oxidative Stress and Restores Osteoblast Function and Bone Formation in Male Mice With Type 1 Diabetes. cGMP, NO
41  2018 Protein kinases G are essential downstream mediators of the antifibrotic effects of sGC stimulators. cGMP, ERK, sGC, SSc, TGF-beta1
42  2018 Stretch-induced compliance: a novel adaptive biological mechanism following acute cardiac load. EDP, LVs, NO, NPs, PT
43  2018 Structural basis for selective inhibition of human PKG Ialpha by the balanol-like compound N46. PKA
44  2018 The anti-diabetic drug dapagliflozin induces vasodilation via activation of PKG and Kv channels. PHE, PKA
45  2018 The Mechanism of Action of Zingerone in the Pacemaker Potentials of Interstitial Cells of Cajal Isolated from Murine Small Intestine. cGMP, GI, ICCs, MAPK, NOS, ODQ, PKC, TRPV1
46  2018 The role of CNP-mediated PKG/PKA-PLCbeta pathway in diabetes-induced gastric motility disorder. cAMP, cGMP, CNP, P-PLCbeta3Ser1105, PKA
47  2018 TRPC5-eNOS Axis Negatively Regulates ATP-Induced Cardiomyocyte Hypertrophy. ATP, NFAT, NO, NRCMs
48  2018 Vildagliptin, an Anti-diabetic Drug of the DPP-4 Inhibitor, Induces Vasodilation via Kv Channel and SERCA Pump Activation in Aortic Smooth Muscle. Kv, PKA
49  2017 A Novel, Direct NO Donor Regulates Osteoblast and Osteoclast Functions and Increases Bone Mass in Ovariectomized Mice. FDA, NO-Cbi
50  2017 Atrial Natriuretic Peptide Affects Stimulus-Secretion Coupling of Pancreatic beta-Cells. ANP, betaGC-A-KO, cGMP, GLP-1, PDE3B, PKA
51  2017 cGMP signaling inhibits platelet shape change through regulation of the RhoA-Rho Kinase-MLC phosphatase signaling pathway. MLC, MLCP, NO, thr853
52  2017 Contribution of the cyclic nucleotide gated channel subunit, CNG-3, to olfactory plasticity in Caenorhabditis elegans. CNG
53  2017 Crosstalk between PKA and PKG controls pH-dependent host cell egress of Toxoplasma gondii. ---
54  2017 Distinct phosphodiesterase 5A-containing compartments allow selective regulation of cGMP-dependent signalling in human arterial smooth muscle cells. ANP, cGMP, ER, HASMC, NO, PDE3A, PDE5A, VASP
55  2017 Effects of nitric oxide on large-conductance Ca2+ -activated K+ currents in human cardiac fibroblasts through PKA and PKG-related pathways. 8-Br-cAMP, 8-BrcGMP, HCF, NO, PKA
56  2017 Examining a role for PKG Ialpha oxidation in the pathogenesis of cardiovascular dysfunction during diet-induced obesity. BAECs, BCNU, cGMP, DAHP, KI, MTX, NO, SMCs, WT
57  2017 GSK-3 mediates NO-cGMP-induced isoflavone production in soybean sprouts. CHS, GSK-3, IFS, NO-cGMP
58  2017 Inhibition of iNOS alleviates cognitive deficits and depression in diabetic mice through downregulating the NO/sGC/cGMP/PKG signal pathway. AG, CFT, cGMP, FST, iNOS, NO, OFT, sGC, TST
59  2017 Mechanisms of the cyclic nucleotide cross-talk signaling network in cardiac L-type calcium channel regulation. AP, CN, E-C, NO, PDEs
60  2017 Neuroprotective potential of high-dose biotin. AD, MS, sGC
61  2017 New dimeric cGMP analogues reduce proliferation in three colon cancer cell lines. ---
62  2017 Nitric oxide is required for the insulin sensitizing effects of contraction in mouse skeletal muscle. NO
63  2017 Nitric oxide signalling and neuronal nitric oxide synthase in the heart under stress. cGMP, NO, sGC
64  2017 NMR insight into myosin-binding subunit coiled-coil structure reveals binding interface with protein kinase G-Ialpha leucine zipper in vascular function. CC, CSP, LZ, MBS
65  2017 Pharmacological Effects of Biotin in Animals. ---
66  2017 Plasma Membrane Association by N-Acylation Governs PKG Function in Toxoplasma gondii. AID, cGMP
67  2017 Prevention of the development of heart failure with preserved ejection fraction by the phosphodiesterase-5A inhibitor vardenafil in rats with type 2 diabetes. cGMP, HFpEF, LV, PDE5A, ZDF
68  2017 Regulation of Intracellular Calcium by Carbon Monoxide in Human Bronchial Epithelial Cells. CO, CORM-2, IP1, PLC, sGC, TG
69  2017 Sildenafil improves blood perfusion in steroid-induced avascular necrosis of femoral head in rabbits via a protein kinase G-dependent mechanism. ANFH, VEGF
70  2017 Sildenafil Prevents Podocyte Injury via PPAR-gamma-Mediated TRPC6 Inhibition. 8-Br-cGMP, cGMP, PPARgamma, TRPC6
71  2017 Sulfhydration-associated phosphodiesterase 5A dimerization mediates vasorelaxant effect of hydrogen sulfide. ELISA, PDE, sGC
72  2017 The bradykinin-cGMP-PKG pathway augments insulin sensitivity via upregulation of MAPK phosphatase-5 and inhibition of JNK. BK, MAPK, NO, sGC
73  2017 The NO-cGMP-PKG signal transduction pathway is involved in the analgesic effect of early hyperbaric oxygen treatment of neuropathic pain. CCI, HBO, sGC
74  2017 The Role of Statins in the Activation of Heme Oxygenase-1 in Cardiovascular Diseases. AP, CVD, ERK, HMG-CoA, HO-1
75  2017 Triiodothyronine Potentiates Vasorelaxation via PKG/VASP Signaling in Vascular Smooth Muscle Cells. ACh, EC, HAEC, NO, SNP, VASP, VSMC
76  2017 Type 5 phosphodiesterase regulates glioblastoma multiforme aggressiveness and clinical outcome. GBM, PARP, PARylation
77  2016 Activation of Protein Kinase G (PKG) Reduces Neointimal Hyperplasia, Inhibits Platelet Aggregation, and Facilitates Re-endothelialization. DES
78  2016 Activation of the sigma receptor 1 modulates AMPA receptor-mediated light-evoked excitatory postsynaptic currents in rat retinal ganglion cells. AMPAR, GCs, L-EPSCs, NMDA, PI, PKA, PKC, PLC, PPR, sigmaR
79  2016 Berberine induces pacemaker potential inhibition via cGMP-dependent ATP-sensitive K+ channels by stimulating mu/delta opioid receptors in cultured interstitial cells of Cajal from mouse small intestine. cGMP, GI, ICCs, PPs
80  2016 Effect of Aurantii Fructus Immaturus Flavonoid on the Contraction of Isolated Gastric Smooth Muscle Strips in Rats. AFIF, ALSMS, cGMP, L-NAME, NOS, PCSMS
81  2016 Electrophysiological effects of natriuretic peptides in the heart are mediated by multiple receptor subtypes. AC, ANP, BNP, CNP, DNP, GC, Gi, NPs, PDE2, PDE3
82  2016 Expression and therapeutic targeting of dopamine receptor-1 (D1R) in breast cancer. D1R, D1Rs, DA
83  2016 Helional induces Ca2+ decrease and serotonin secretion of QGP-1 cells via a PKG-mediated pathway. EC, OR
84  2016 IP3 Mediates Nitric Oxide-Guanosine 3',5'-Cyclic Monophosphate (NO-cGMP)-Induced Isoflavone Accumulation in Soybean Sprouts under UV-B Radiation. CHS, IFS, NO-cGMP, PI-PLC, SNP
85  2016 Is enhancing cGMP-PKG signalling a promising therapeutic target for heart failure with preserved ejection fraction? cGMP
86  2016 Liraglutide prevents and reverses monocrotaline-induced pulmonary arterial hypertension by suppressing ET-1 and enhancing eNOS/sGC/PKG pathways. cGMP, eNOS, GLP-1R, MCT, PAH, PASMCs, PDGF
87  2016 Molsidomine Attenuates Ventricular Electrical Remodeling and Arrhythmogenesis in Rats With Chronic beta-Adrenergic Receptor Activation Through the NO/cGMP/PKG Pathway. ISO, ISO, NO, Smax, VTs
88  2016 Muscarinic Stimulation Facilitates Sarcoplasmic Reticulum Ca Release by Modulating Ryanodine Receptor 2 Phosphorylation Through Protein Kinase G and Ca/Calmodulin-Dependent Protein Kinase II. ---
89  2016 Myocardial Microvascular Inflammatory Endothelial Activation in Heart Failure With Preserved Ejection Fraction. cGMP, Ctrl, HFpEF, LV, NO, ZSF1
90  2016 Nitric oxide increases the migratory activity of non-small cell lung cancer cells via AKT-mediated integrin alphav and beta1 upregulation. FAK, NO, NSCLC
91  2016 Nitric Oxide Regulates The Lymphatic Reactivity Following Hemorrhagic Shock Through Atp-Sensitive Potassium Channel. cGMP, L-NAME, NO
92  2016 Nitric oxide/cGMP/PKG signaling pathway activated by M1-type muscarinic acetylcholine receptor cascade inhibits Na+-activated K+ currents in Kenyon cells. 4-DAMP, KNa, l-NAME, NO, NOS, sGC, SNAP
93  2016 Old dog, new tricks: novel cardiac targets and stress regulation by protein kinase G. cGMP, HF
94  2016 Pharmacological modulation of protein kinases as a new approach to treat addiction to cocaine and opiates. CaMKII, Cdk5, ERK, HSP, MAPK, mTOR, PI3K, PKA, PKC
95  2016 Phosphodiesterase 5/protein kinase G signal governs stemness of prostate cancer stem cells through Hippo pathway. CSC, PCSC, PDE5
96  2016 Phosphorylation increases the catalytic activity of rainbow trout gill cytosolic carbonic anhydrase. CAc, k cat
97  2016 PKG-1alpha mediates GATA4 transcriptional activity. ---
98  2016 Protein Kinase G facilitates EGFR-mediated cell death in MDA-MB-468 cells. EGFR
99  2016 Protein kinase G signaling in cardiac pathophysiology: Impact of proteomics on clinical trials. cGMP
100  2016 Receptor-Type Guanylyl Cyclase at 76C (Gyc76C) Regulates De Novo Lumen Formation during Drosophila Tracheal Development. Arl3, DT, E-cad, Gyc76C