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■ Abbreviation / Long Form : PPADS / pyridoxalphosphate-6-azophenyl-2',4'-disulphonic acid

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Total Number of Papers: 373
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Abbreviation:   PPADS  (>> Co-occurring Abbreviation)
Long Form:   pyridoxalphosphate-6-azophenyl-2',4'-disulphonic acid
 Abbreviation Variation
 Long Form Variation
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No. Year Title Co-occurring Abbreviation
2019 Complementary Role of P2 and Adenosine Receptors in ATP Induced-Anti-Apoptotic Effects Against Hypoxic Injury of HUVECs. ATP, NOS, PI3K, PKA
2019 Intercellular Ca2+ signalling in the adult mouse cochlea. ---
2018 A Purinergic P2 Receptor Family-Mediated Increase in Thrombospondin-1 Bolsters Synaptic Density and Epileptic Seizure Activity in the Amygdala-Kindling Rat Model. IR, siRNA
2018 ATP in the lateral hypothalamus/perifornical area enhances the CO2 chemoreflex control of breathing. alpha,beta-meATP, LH/PFA
2018 Mapping the binding site of the P2X receptor antagonist PPADS reveals the importance of orthosteric site charge and the cysteine-rich head region. CRH, P2XR
2018 TRPV4 Stimulation Releases ATP via Pannexin Channels in Human Pulmonary Fibroblasts. ---
2017 Blockade of ATP P2X7 receptor enhances ischiatic nerve regeneration in mice following a crush injury. BBG, SFI
2017 P2X-Receptor Antagonists Inhibit the Interaction of S. aureus Hemolysin A with Membranes. oxATP
2017 Purinergic Antagonism Prevents Mitochondrial Dysfunction and Behavioral Deficits Associated with Dopaminergic Toxicity Induced by 6-OHDA in Rats. ATP, BBG, DA, PD
10  2017 Viability of SH-SY5Y cells is associated with purinergic P2 receptor expression alterations. ---
11  2017 [Effects of lappaconitine on pain and inflammatory response of severely burned rats and the mechanism]. IL-1beta, LA, PIH, PWMT, TNF-alpha, TNP
12  2016 Diadenosine tetra- and pentaphosphates affect contractility and bioelectrical activity in the rat heart via P2 purinergic receptors. AP, PVs
13  2016 Purinergic receptor blockade in the retrotrapezoid nucleus attenuates the respiratory chemoreflexes in awake rats. ATP, RTN
14  2016 Subcellular propagation of calcium waves in Muller glia does not require autocrine/paracrine purinergic signaling. ER, SOCE, TRPC1
15  2016 TNP-ATP is Beneficial for Treatment of Neonatal Hypoxia-Induced Hypomyelination and Cognitive Decline. TNP-ATP
16  2015 Functional properties of submucosal venules in the rat stomach. CPA, SMCs, TNS
17  2015 Involvement of a P2X7 Receptor in the Acrosome Reaction Induced by ATP in Rat Spermatozoa. AR, BB-G, BzATP, oATP
18  2015 P2 purinergic receptor activation of neuronal nitric oxide synthase and guanylyl cyclase in the dorsal facial area of the medulla increases blood flow in the common carotid arteries of cats. CCA, DFA, NO, NOS
19  2015 Properties of ATP-gated ion channels assembled from P2X2 subunits in mouse cochlear Reissner's membrane epithelial cells. ADP, ATP, mRNA
20  2015 The effects of extracellular ATP and its receptor antagonists on pig oocytes during in vitro maturation. COs, RB2
21  2014 ATP in the locus coeruleus as a modulator of cardiorespiratory control in unanaesthetized male rats. alpha,beta-meATP, HR, LC, MAP
22  2014 ATP metabolism in skeletal muscle arterioles. ATP
23  2014 Extracellular ADP prevents neuronal apoptosis via activation of cell antioxidant enzymes and protection of mitochondrial ANT-1. ANT-1
24  2014 Measurement of ATP-Induced Membrane Potential Changes in IVD cells. AF, ATP, di-8-ANEPPS, IVD, NP
25  2014 Purinergic 2X receptors play a role in evoking the exercise pressor reflex in rats with peripheral artery insufficiency. P2X
26  2014 Role of peripheral purinoceptors in the development of bee venom-induced nociception: a behavioural and electrophysiological study in rats. ---
27  2014 Toll-like receptor-triggered calcium mobilization protects mice against bacterial infection through extracellular ATP release. CBX, eATP, FFA, IL-1beta, LPS, NEM, TG, TLR
28  2013 Differences in purinergic amplification of osmotic cell lysis by the pore-forming RTX toxins Bordetella pertussis CyaA and Actinobacillus pleuropneumoniae ApxIA: the role of pore size. RTX
29  2013 Suppression of ATP-induced excitability in rat small-diameter trigeminal ganglion neurons by activation of GABAB receptor. ---
30  2012 A reassessment of P2X7 receptor inhibition as a neuroprotective strategy in rat models of contusion injury. BBG, SCI
31  2012 P2X purinergic receptor knockout mice reveal endogenous ATP modulation of both vasopressin and oxytocin release from the intact neurohypophysis. HNS, NH, OT, R KO, WT
32  2012 P2Y2 receptor activation opens pannexin-1 channels in rat carotid body type II cells: potential role in amplifying the neurotransmitter ATP. CB, DIDS, GCs, P2Y2Rs, Panx-1, PNs
33  2012 Prejunctional facilitatory effect of a thiol-alkylating agent N-Ethylmaleimide on neurogenic contractions in rat prostate smooth muscle. EFS, NEM
34  2012 Purinergic modulation of hypoxic regulation via the rostral ventral lateral medulla in rats. ATP, RVLM
35  2011 ATP differentially upregulates fibroblast growth factor 2 and transforming growth factor alpha in neonatal and adult mice: effect on neuroproliferation. BrdU, FGF-2, OE, TGF alpha
36  2011 ATP induces contraction mediated by the P2Y(2) receptor in rat intestinal subepithelial myofibroblasts. IMFs
37  2011 beta-nicotinamide adenine dinucleotide is an enteric inhibitory neurotransmitter in human and nonhuman primate colons. ATP, beta-NAD, SMCs
38  2011 Calcium dependence of purinergic subtype P2Y₁ receptor modulation of C6 glioma cell migration. 2-MeSADP, SOC
39  2011 Carotid chemoafferent activity is not necessary for all phrenic long-term facilitation following acute intermittent hypoxia. AIH, pLTF
40  2011 Extracellular ATP activates NFAT-dependent gene expression in neuronal PC12 cells via P2X receptors. BDNF
41  2011 Extracellular nucleotides affect pericyte-mediated regulation of rat in situ vasa recta diameter. BzATP, RB2
42  2011 Facilitation of glutamate and GABA release by P2X receptor activation in supraoptic neurons from freshly isolated rat brain slices. SON
43  2011 Functional and morphological examinations of P1A1 purinoceptors in the normal and inflamed urinary bladder of the rat. CYP, DPCPX
44  2011 The P2 receptor antagonist PPADS supports recovery from experimental stroke in vivo. ATP, MCAO
45  2010 Alteration in skeletal muscle afferents in rats with chronic heart failure. CHF, DRG, EPR, P2X
46  2010 Characterization of nestin expression in the spinal cord of GFP transgenic mice after peripheral nerve injury. L5 SNT, pNestin-GFP
47  2010 Oxybutynin and propiverine suppress adenosine triphosphate-induced bladder overactivity other than through antimuscarinic mechanisms. 4-DAMP, ATP, ICI, PT
48  2010 P2Y2 receptors mediate ATP-induced resensitization of TRPV1 expressed by kidney projecting sensory neurons. FB, TRPV1
49  2010 Peripheral purinergic receptor modulation influences the trigeminal ganglia nitroxidergic system in an experimental murine model of inflammatory orofacial pain. ---
50  2010 Purinergic receptor functionality is necessary for infection of human hepatocytes by hepatitis delta virus and hepatitis B virus. BBG, HBV, HDV, PHH
51  2009 5-HT2 receptors modulate excitatory neurotransmission to cardiac vagal neurons within the nucleus ambiguus evoked during and after hypoxia. CVNs, EPSCs, NA
52  2009 ATP induces long-term potentiation of C-fiber-evoked field potentials in spinal dorsal horn: the roles of P2X4 receptors and p38 MAPK in microglia. ATP, LTP, p-p38 MAPK, TNP-ATP
53  2009 Cell density-dependent changes in intracellular Ca2+ mobilization via the P2Y2 receptor in rat bone marrow stromal cells. BMSCs, PCNA
54  2009 Extracellular ATP induces retinal photoreceptor apoptosis through activation of purinoceptors in rodents. ATP, CNS, RP
55  2009 Extrinsic afferent nerve sensitivity and enteric neurotransmission in murine jejunum in vitro. ---
56  2009 Increase of intracellular Ca2+ by P2Y but not P2X receptors in cultured cortical multipolar neurons of the rat. AP5, CNQX, IR
57  2009 Interaction of hydrocortisone with ATP and adenosine on nerve-mediated contractions of frog skeletal muscle. EFS
58  2009 Investigation of the role of adrenergic and non-nitrergic, non-adrenergic neurotransmission in the sheep isolated internal anal sphincter. ATP, EFS, L-NAME, VIP
59  2009 Mechanism of ATP-induced local and conducted vasomotor responses in isolated rat cerebral penetrating arterioles. ATP, Ca, MS-PPOH
60  2009 Mechanism of stretch-activated excitatory and inhibitory responses in the lower esophageal sphincter. ICC, LES
61  2009 Modulation of firing activity by ATP in dopamine neurons of the rat substantia nigra pars compacta. 2MeSATP, RT-PCR, SNc
62  2009 P2X antagonists inhibit styryl dye entry into hair cells. TNP-ATP
63  2009 Pharmacological properties of ATP-sensitive purinergic receptors expressed in human G292 osteoblastic cells. alpha,beta-meATP, BzATP, TNP-ATP
64  2009 Purinergic contribution to small intestinal afferent hypersensitivity in a murine model of postinfectious bowel disease. ---
65  2009 Purinergic receptor activation evokes neurotrophic factor neuropeptide Y release from neonatal mouse olfactory epithelial slices. NPY
66  2009 The role of 5-HT3 and other excitatory receptors in central cardiorespiratory responses to hypoxia: implications for sudden infant death syndrome. CVNs, NA
67  2008 5HT2 receptor activation facilitates P2X receptor mediated excitatory neurotransmission to cardiac vagal neurons in the nucleus ambiguus. alpha,beta-Me-ATP, alpha-Me-5-HT, CVNs, mCPP, mEPSCs, NA
68  2008 ATP activates P2x receptors and requires extracellular Ca(++) participation to modify outer hair cell nonlinear capacitance. DIDS, NLC, OHC
69  2008 Changes in the control of gastric motor activity during metamorphosis in the amphibian Xenopus laevis, with special emphasis on purinergic mechanisms. DPCPX, TTX, UTP
70  2008 Characterization of calcium-independent purinergic receptor-mediated apoptosis in hormone-refractory prostate cancer. HRPC
71  2008 Connexins 37 and 40 transduce purinergic signals mediating renal autoregulation. CPX, Cx, GFR
72  2008 Diadenosine polyphosphates are selective vasoconstrictors in human coronary artery bypass grafts. ---
73  2008 Effect of PPADS on achondroplasic chondrocytes: inhibition of FGF receptor type 3 over-activity. FGF9
74  2008 Hypotensive effect of UDP on intraocular pressure in rabbits. IOP, RB2
75  2008 Negative and positive allosteric modulators of the P2X(7) receptor. ---
76  2008 P2X1 and P2X5 subunits form the functional P2X receptor in mouse cortical astrocytes. ---
77  2008 PARTICIPATION OF EXTRACELLULAR NUCLEOTIDES IN THE WOUND RESPONSE OF DASYCLADUS VERMICULARIS AND ACETABULARIA ACETABULUM (DASYCLADALES, CHLOROPHYTA)(1). ADPbetaS, AMPS, ATPgammaS, NO
78  2008 PPADS does not block contraction-induced prostaglandin E2 synthesis in cat skeletal muscle. PGE2
79  2008 PPADS, a purinergic antagonist reduces Fos expression at spinal cord level in a mouse model of mononeuropathy. ---
80  2008 Recruitment of excitatory serotonergic neurotransmission to cardiac vagal neurons in the nucleus ambiguus post hypoxia and hypercapnia. AP5, CNQX, CVNs, EPSCs, NMDA, TNP-ATP
81  2008 The purinergic antagonist PPADS reduces pain related behaviours and interleukin-1 beta, interleukin-6, iNOS and nNOS overproduction in central and peripheral nervous system after peripheral neuropathy in mice. NOS
82  2008 Therapeutic effects of the putative P2X3/P2X2/3 antagonist A-317491 on cyclophosphamide-induced cystitis in rats. CYP, SD
83  2008 Volume-activated chloride channels in mice Leydig cells. LH, NPPB
84  2007 Adenosine triphosphate increases the reactivity of the afferent arteriole to low concentrations of norepinephrine. Af, ATP, NE
85  2007 ATP modulates cell proliferation and elicits two different electrophysiological responses in human mesenchymal stem cells. ATP, hMSCs
86  2007 Blockade of purinergic 2 receptors attenuates the mechanoreceptor component of the exercise pressor reflex. ---
87  2007 Ca2+-dependent ATP release from A549 cells involves synergistic autocrine stimulation by coreleased uridine nucleotides. ER, TG
88  2007 Characterization of functional P2X(1) receptors in mouse megakaryocytes. RB2, TNP-ATP
89  2007 Contractile activity of ATP and diadenosine tetraphosphate on urinary bladder in the rat: role of A1- and P2X-purinoceptors and nitric oxide. ATP, DPCPX, NO
90  2007 Developmental changes of purinergic control of intestinal motor activity during metamorphosis in the African clawed frog, Xenopus laevis. alpha-beta-MeATP, ATPgammaS, DPCPX
91  2007 Existence of high and low affinity dinucleotides pentaphosphate-induced calcium responses in individual synaptic terminals and lack of correlation with the distribution of P2X1-7 subunits. ---
92  2007 Extracellular interconversion of nucleotides reveals an ecto-adenylate kinase activity in the rat hippocampus. ADP, AMP, ATP, UDP
93  2007 Identification of atropine- and P2X1 receptor antagonist-resistant, neurogenic contractions of the urinary bladder. alpha,beta-meATP
94  2007 P19 embryonal carcinoma cells as in vitro model for studying purinergic receptor expression and modulation of N-methyl-D-aspartate-glutamate and acetylcholine receptors during neuronal differentiation. NMDA
95  2007 P2 purinoceptor antagonists inhibit the non-adrenergic, non-cholinergic relaxation of the human colon in vitro. L-NOARG, NANC, NO
96  2007 P2X7 receptors mediate NADH transport across the plasma membranes of astrocytes. P2X7R
97  2007 Prevention of liver fibrosis by the purinoceptor antagonist pyridoxal-phosphate-6-azophenyl-2',4'-disulfonate (PPADS). HSC
98  2007 Purinergic actions on neurons that modulate nociception in the rostral ventromedial medulla. 8-PT, RVM
99  2007 Purinergic control of the quail rectum: modulation of adenosine 5'-triphosphate-mediated contraction with acetylcholine. EFS
100  2007 Purinergic modulation of respiration via medullary raphe nuclei in rats. RM, RP