A Search Service for Abbreviation / Long Form

■ Abbreviation / Long Form : Pyk2 / proline-rich tyrosine kinase 2

[Related PubMed/MEDLINE]
Total Number of Papers: 269
[Display Entries]
100 entries :
     (Publication year, Descending)
100 entries :
     (Publication year, Ascending)
>> all entries
[Entries Per Page]
 per page
Page Control
Page: of
Abbreviation:   Pyk2  (>> Co-occurring Abbreviation)
Long Form:   proline-rich tyrosine kinase 2
 Abbreviation Variation
 Long Form Variation
 Pair(Abbreviation/Long Form) Variation
No. Year Title Co-occurring Abbreviation
2020 Characterization of Integrin alphaIIbbeta3-Mediated Outside-in Signaling by Protein Kinase Cdelta in Platelets. PKCdelta, WT
2020 Down-Regulation of DDR1 Induces Apoptosis and Inhibits EMT through Phosphorylation of Pyk2/MKK7 in DU-145 and Lncap-FGC Prostate Cancer Cell Lines. DDR1, EMT, MKK7
2020 FAK Family Kinases in Vascular Diseases. ECM, FAK, VSMCs
2020 FAK Promotes Early Osteoprogenitor Cell Proliferation by Enhancing mTORC1 Signaling. BMSCs, FAK, mTORC1
2020 Fyn-mediated phosphorylation of Pyk2 promotes its activation and dissociation downstream of gonadotropin-releasing hormone receptor. GnRH, PKD1, Tyr402
2020 Pyk2 downstream of G12/13 pathways regulates platelet shape change through RhoA/p160ROCK. MYPT1, PAR1
2020 Recognition of LD motifs by the focal adhesion targeting domains of focal adhesion kinase and proline-rich tyrosine kinase 2-beta: Insights from molecular dynamics simulations. FAK, FAs, FAT, HSQC NMR
2020 Roles of Pyk2 in signal transduction after gonadotropin-releasing hormone receptor stimulation. EGFR, ERK1, GnRH, Grb2
2020 S92 phosphorylation induces structural changes in the N-terminus domain of human mitochondrial calcium uniporter. AMPK, MCU, NTD, S92p
10  2019 Activation of Pyk2 by CaM kinase II in cultured hypothalamic neurons and gonadotroph cells. ERK, GnRH
11  2019 Beta1 integrin blockade overcomes doxorubicin resistance in human T-cell acute lymphoblastic leukemia. ECM, T-ALL
12  2019 Commentary on Giralt et al.: PTK2B/Pyk2 overexpression improves a mouse model of Alzheimer's disease. AD
13  2019 CRISPR/Cas9 engineering of ERK5 identifies its FAK/PYK2 dependent role in adhesion-mediated cell survival. ERK5, FAK
14  2019 EGFR signaling pathway occupies an important position in cancer-related downstream signaling pathways of Pyk2. EGFR, FAK
15  2019 Glucocorticoid-Induced Bone Fragility Is Prevented in Female Mice by Blocking Pyk2/Anoikis Signaling. GCs, KO, PF
16  2019 Glycolipid iGb3 feedback amplifies innate immune responses via CD1d reverse signaling. APCs, CD1d, GSLs, IKKbeta, NKT cells, TBK1, TLR
17  2019 Lipopolysaccharide-Induced Matrix Metalloproteinase-9 Expression Associated with Cell Migration in Rat Brain Astrocytes. AP-1, ChIP, JNK, LPS, MAPK, MMP, PDGFR, PI3K, TLRs
18  2019 PYK2 Is Involved in Premalignant Acinar Cell Reprogramming and Pancreatic Ductal Adenocarcinoma Maintenance by Phosphorylating beta-CateninY654. ADM, PanIN, PDAC
19  2019 Retraction: Proline-Rich Tyrosine Kinase 2 (Pyk2) Regulates IGF-I-Induced Cell Motility and Invasion of Urothelial Carcinoma Cells. ---
20  2019 Silencing Nogo-B receptor inhibits penile corpus cavernosum vascular smooth muscle cell apoptosis of rats with diabetic erectile dysfunction by down-regulating ICAM-1. alpha-SMA, Bax, Bcl-2, ED, ICAM-1, ICP, MAP, NgBR, SRC
21  2019 Trpm2 enhances physiological bioenergetics and protects against pathological oxidative cardiac injury: Role of Pyk2 phosphorylation. BAPTA, I/R, KO, WT
22  2019 Tyrosine kinase Pyk2 is involved in colonic smooth muscle contraction via the RhoA/ROCK pathway. CSMCs, GI, MLCK, TTX
23  2019 Tyrosine phosphorylation signaling regulates Ca2+ entry by affecting intracellular pH during human sperm capacitation. pTyr
24  2018 Activated proline-rich tyrosine kinase 2 regulates meiotic spindle assembly in the mouse oocyte. ---
25  2018 Activation of Phosphotyrosine-Mediated Signaling Pathways in the Cortex and Spinal Cord of SOD1G93A, a Mouse Model of Familial Amyotrophic Lateral Sclerosis. ALS, NMDAR, STEP
26  2018 Endogenous Control Mechanisms of FAK and PYK2 and Their Relevance to Cancer Development. FAK
27  2018 Focal adhesion kinase a potential therapeutic target for pancreatic cancer and malignant pleural mesothelioma. ECIS, FAK, MPM, PDAC
28  2018 Galangin Inhibits Thrombin-Induced MMP-9 Expression in SK-N-SH Cells via Protein Kinase-Dependent NF-kappaB Phosphorylation. Akt, FOXO1, JNK, MAPK, MMPs, mTOR, PKC
29  2018 Haem oxygenase-1 up-regulation by rosiglitazone via ROS-dependent Nrf2-antioxidant response elements axis or PPARgamma attenuates LPS-mediated lung inflammation. ARE, HO-1, HPAEpiCs, NOX, Nrf2
30  2018 Proline-Rich Protein Tyrosine Kinase 2 in Inflammation and Cancer. FAK
31  2018 Pyk2 and FAK differentially regulate invadopodia formation and function in breast cancer cells. Arg, FAK
32  2018 Pyk2 deficiency potentiates osteoblast differentiation and mineralizing activity in response to estrogen or raloxifene. ALP, ERalpha, ERbeta, OBs, SERMs
33  2018 Pyk2 promotes tumor progression in renal cell carcinoma. RCC
34  2018 Regulation of gastric smooth muscle contraction via Ca2+-dependent and Ca2+-independent actin polymerization. FAK, MLC, PAK, PLC
35  2018 Role of Pyk2 in Human Cancers. ---
36  2018 The human ion channel TRPM2 modulates neuroblastoma cell survival and mitochondrial function through Pyk2, CREB, and MCU activation. CREB, MCU, TRPM2
37  2018 The Pyk2/MCU pathway in the rat middle cerebral artery occlusion model of ischemic stroke. HUK, MCU
38  2018 [Expression and clinical significance of proline-rich tyrosine kinase 2 and phospho-protein kinase B in tongue squamous cell carcinoma]. p-AKT, TSCC
39  2017 An in silico high-throughput screen identifies potential selective inhibitors for the non-receptor tyrosine kinase Pyk2. FAK
40  2017 CF airway smooth muscle transcriptome reveals a role for PYK2. CF
41  2017 Curcumin modulation of the activation of PYK2 in peripheral blood mononuclear cells from patients with lupus nephritis. LN, PBMCs, SLE
42  2017 Hydrogen Sulfide Preserves Endothelial Nitric Oxide Synthase Function by Inhibiting Proline-Rich Kinase 2: Implications for Cardiomyocyte Survival and Cardioprotection. CSE, eNOS, NO
43  2017 Non-canonical pathway induced by Wnt3a regulates beta-catenin via Pyk2 in differentiating human neural progenitor cells. CaMKII, GSK3beta, hNPCs
44  2017 PYK2 mediates BzATP-induced extracellular matrix proteins synthesis. ATP, BzATP, ECMP, OPN
45  2017 The nonreceptor protein tyrosine kinase Pyk2 promotes the turnover of monocytes at steady state. BM
46  2017 Tyrosine phosphorylation of eNOS regulates myocardial survival after an ischaemic insult: role of PYK2. I/R, NO
47  2017 Vibrio vulnificus MARTX cytotoxin causes inactivation of phagocytosis-related signaling molecules in macrophages. FAK, PI3K, SFKs
48  2016 CCL18 from ascites promotes ovarian cancer cell migration through proline-rich tyrosine kinase 2 signaling. OC
49  2016 CD19 controls Toll-like receptor 9 responses in human B cells. BCR, BTK, MYD88, PI3K, TACI, TLR
50  2016 Convergent Effects of Resveratrol and PYK2 on Prostate Cells. ---
51  2016 Localized Irradiation of Cell Membrane by Auger Electrons Is Cytotoxic Through Oxidative Stress-Mediated Nontargeted Effects. JNK, MBCD, PLCgamma
52  2016 Novel Role of Src in Priming Pyk2 Phosphorylation. FAK
53  2016 pH sensors and ion Transporters: Potential therapeutic targets for acid-base disorders. GPR4
54  2016 Proline-rich tyrosine kinase 2 downregulates peroxisome proliferator-activated receptor gamma to promote hypoxia-induced pulmonary artery smooth muscle cell proliferation. HPASMCs, NF-kappaB, NOX4, PH, PPARgamma, siRNA
55  2016 Proline-rich tyrosine kinase 2 via enhancing signal transducer and activator of transcription 3-dependent cJun expression mediates retinal neovascularization. HRMVEC, STAT3, VEGF-A
56  2016 Pyk2 is essential for astrocytes mobility following brain lesion. FAK, TNF-alpha
57  2016 PYK2 via S6K1 regulates the function of androgen receptors and the growth of prostate cancer cells. AR, PCa, S6K1
58  2016 Regulation of arterial reactivity by concurrent signaling through the E-prostanoid receptor 3 and angiotensin receptor 1. Ang II, AT1, EP3, PGE2
59  2016 Structural Basis for the Interaction between Pyk2-FAT Domain and Leupaxin LD Repeats. FAK, FAT
60  2016 Subcellular localization of proline-rich tyrosine kinase 2 during oocyte fertilization and early-embryo development in mice. p-Pyk2
61  2016 Targeting PYK2 mediates microenvironment-specific cell death in multiple myeloma. BMSC, FA, MM, STAT3
62  2016 The iron chelator deferasirox induces apoptosis by targeting oncogenic Pyk2/beta-catenin signaling in human multiple myeloma. DFX, MM
63  2016 The Tyrosine Kinase Pyk2 Contributes to Complement-Mediated Phagocytosis in Murine Macrophages. FAK, FcgammaR
64  2016 Up-regulation of N-cadherin by Collagen I-activated Discoidin Domain Receptor 1 in Pancreatic Cancer Requires the Adaptor Molecule Shc1. DDR1, EMT
65  2015 A phase I study of VS-6063, a second-generation focal adhesion kinase inhibitor, in patients with advanced solid tumors. FAK
66  2015 Chemokine receptor 7 promotes tumor migration and invasiveness via the RhoA/ROCK pathway in metastatic squamous cell carcinoma of the head and neck. CCR7, ROCK, SCCHN
67  2015 Involvement of ROS-alpha v beta 3 integrin-FAK/Pyk2 in the inhibitory effect of melatonin on U251 glioma cell migration and invasion under hypoxia. alphavbeta3, DCFH-DA, FAK, ROS, siRNA
68  2015 Microglia Activate Migration of Glioma Cells through a Pyk2 Intracellular Pathway. FAK
69  2015 Pyk2 aggravates hypoxia-induced pulmonary hypertension by activating HIF-1alpha. PAH, PH
70  2015 Regulation of NHE3 by lysophosphatidic acid is mediated by phosphorylation of NHE3 by RSK2. EGFR, LPA, NHE3, PDK1
71  2015 Regulation of the cystic fibrosis transmembrane conductance regulator anion channel by tyrosine phosphorylation. CFTR
72  2015 Retraction Note To: Functional activation of Proline-rich Tyrosine Kinase2 (PYK2) in peripheral blood mononuclear cells from patients with systemic lupus erythematosus. ---
73  2015 S-Nitrosylation of proline-rich tyrosine kinase 2 involves its activation induced by oxygen-glucose deprivation. NMDA, OGD, ROS
74  2015 The role of Pyk2 in the CCR7-mediated regulation of metastasis and viability in squamous cell carcinoma of the head and neck cells in vivo and in vitro. CCR7, SCCHN
75  2015 The upregulation of NR2A-containing N-methyl-D-aspartate receptor function by tyrosine phosphorylation of postsynaptic density 95 via facilitating Src/proline-rich tyrosine kinase 2 activation. LTP, NMDA, PSD-95
76  2014 Adrenergic signaling regulates mitochondrial Ca2+ uptake through Pyk2-dependent tyrosine phosphorylation of the mitochondrial Ca2+ uniporter. alpha1-AR
77  2014 c-Src and Pyk2 protein tyrosine kinases play protective roles in early HIV-1 infection of CD4+ T-cell lines. DN
78  2014 Cbl-b accelerates trypsin-induced cell detachment through ubiquitination and degradation of proline-rich tyrosine kinase 2. ---
79  2014 Evidence for the involvement of proline-rich tyrosine kinase 2 in tyrosine phosphorylation downstream of protein kinase A activation during human sperm capacitation. FAK, PKA, Tyr
80  2014 Functions of the FAK family kinases in T cells: beyond actin cytoskeletal rearrangement. FAK, TCR
81  2014 Induction of proline-rich tyrosine kinase 2 activation-mediated C6 glioma cell invasion after anti-vascular endothelial growth factor therapy. FAK, VEGF
82  2014 Microparticles Mediate the Intercellular Regulation of microRNA-503 and Proline-Rich Tyrosine Kinase 2 to Alter the Migration and Invasion Capacity of Breast Cancer Cells. miRNAs, MPs
83  2014 Noncanonical G-protein-dependent modulation of osteoclast differentiation and bone resorption mediated by Pasteurella multocida toxin. PKC, PMT, RANKL
84  2014 Pivotal roles of regulating the proline-rich tyrosine kinase 2 (PYK2) signaling in cardiac function and remodeling. ---
85  2014 Pyk2 promotes tumor progression in multiple myeloma. MM
86  2014 PYK2 selectively mediates signals for growth versus differentiation in response to stretch of spontaneously active vascular smooth muscle. ---
87  2014 Role for NUP62 depletion and PYK2 redistribution in dendritic retraction resulting from chronic stress. NPC, NUP62
88  2014 Store-operated Ca(2+) entry regulates glioma cell migration and invasion via modulation of Pyk2 phosphorylation. MTT
89  2014 Structural and mechanistic insights into the interaction between Pyk2 and paxillin LD motifs. FAK, FAT
90  2014 TRPM2 contributes to LPS/IFNgamma-induced production of nitric oxide via the p38/JNK pathway in microglia. DPI, ERK, JNK, NO, p38 MAPK, TRPM2, WT
91  2014 Tyrosine 402 phosphorylation of Pyk2 is involved in ionomycin-induced neurotransmitter release. DA
92  2013 Distinct role of Pyk2 in mediating thromboxane generation downstream of both G12/13 and integrin alphaIIbbeta3 in platelets. ---
93  2013 High expression of proline-rich tyrosine kinase 2 is associated with poor survival of hepatocellular carcinoma via regulating phosphatidylinositol 3-kinase/AKT pathway. HCC, PI3K, VEGF
94  2013 Proline-rich tyrosine kinase 2 and its phosphorylated form pY881 are novel prognostic markers for non-small-cell lung cancer progression and patients' overall survival. IHC, NSCLC
95  2013 Pyk2 cytonuclear localization: mechanisms and regulation by serine dephosphorylation. ---
96  2013 SHP-1-Pyk2-Src protein complex and p38 MAPK pathways independently regulate IL-10 production in lipopolysaccharide-stimulated macrophages. WT
97  2012 Chemokine receptor 7 via proline-rich tyrosine kinase-2 upregulates the chemotaxis and migration ability of squamous cell carcinoma of the head and neck. CCR7, SCCHN
98  2012 Glycogen synthase kinase-3beta is critical for interferon-alpha-induced serotonin uptake in human Jurkat T cells. CaMKII, ERK, GSK, IFN-alpha, shRNAs, STAT
99  2012 Inhibition of Pyk2 blocks lung inflammation and injury in a mouse model of acute lung injury. ALI
100  2012 Proline-rich tyrosine kinase 2 (Pyk2) regulates IGF-I-induced cell motility and invasion of urothelial carcinoma cells. FAK, IGF-IR