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■ Abbreviation / Long Form : RTX / repeats-in-toxin

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Total Number of Papers: 93
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Abbreviation:   RTX  (>> Co-occurring Abbreviation)
Long Form:   repeats-in-toxin
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No. Year Title Co-occurring Abbreviation
2020 Aggregatibacter actinomycetemcomitans leukotoxin: From mechanism to targeted anti-toxin therapeutics. LFA-1
2020 Calcium-Induced Activity and Folding of a Repeat in Toxin Lipase from Antarctic Pseudomonas fluorescens Strain AMS8. CD, DLS, FTIR, ITC
2019 Genetics, Toxicity, and Distribution of Enterohemorrhagic Escherichia coli Hemolysin. EHEC, HC, HUS, LEE, Stx
2019 Rapid Purification of Endotoxin-Free RTX Toxins. HlyA, T1SS
2019 RTX Toxins Ambush Immunity's First Cellular Responders. ---
2019 The Extracellular Domain of the beta2 Integrin beta Subunit (CD18) Is Sufficient for Escherichia coli Hemolysin and Aggregatibacter actinomycetemcomitans Leukotoxin Cytotoxic Activity. ---
2018 Calcium-dependent disorder-to-order transitions are central to the secretion and folding of the CyaA toxin of Bordetella pertussis, the causative agent of whooping cough. ---
2018 Comparative analysis of humoral immune responses and pathologies of BALB/c and C57BL/6 wildtype mice experimentally infected with a highly virulent Rodentibacter pneumotropicus (Pasteurella pneumotropica) strain. Ig, Th
2018 Conserved structural features anchor biofilm-associated RTX-adhesins to the outer membrane of bacteria. RI, RIN
10  2018 Membrane localization of the Repeats-in-Toxin (RTX) Leukotoxin (LtxA) produced by Aggregatibacter actinomycetemcomitans. LFA-1
11  2018 Receptor-Based Peptides for Inhibition of Leukotoxin Activity. LAP, LFA-1
12  2018 Structural requirement of the hydrophobic region of the Bordetella pertussis CyaA-hemolysin for functional association with CyaC-acyltransferase in toxin acylation. ---
13  2018 Type 1 Does the Two-Step: Type 1 Secretion Substrates with a Functional Periplasmic Intermediate. BTLCP, T1SS
14  2018 Whole genome sequencing of Moraxella bovoculi reveals high genetic diversity and evidence for interspecies recombination at multiple loci. IBK, SNP
15  2017 Block V RTX Domain of Adenylate Cyclase from Bordetella pertussis: A Conformationally Dynamic Scaffold for Protein Engineering Applications. ---
16  2017 Catch and Release: Engineered Allosterically Regulated beta-Roll Peptides Enable On/Off Biomolecular Recognition. ---
17  2017 Characterization of Post-Translational Modifications and Cytotoxic Properties of the Adenylate-Cyclase Hemolysin Produced by Various Bordetella pertussis and Bordetella parapertussis Isolates. AC-Hly, PTMs
18  2017 Conditional Network Assembly and Targeted Protein Retention via Environmentally Responsive, Engineered beta-Roll Peptides. ---
19  2017 Detection of Actinobacillus Pleuropneumoniae ApxIV Toxin Antibody in Serum and Oral Fluid Specimens from Pigs Inoculated Under Experimental Conditions. dpi, ELISAs, LPS
20  2017 Fine Epitope Mapping of Two Antibodies Neutralizing the Bordetella Adenylate Cyclase Toxin. ACT
21  2017 Functional Contributions of Positive Charges in the Pore-Lining Helix 3 of the Bordetella pertussis CyaA-Hemolysin to Hemolytic Activity and Ion-Channel Opening. CyaA-Hly, PLBs
22  2017 Pathogenic Acinetobacter species have a functional type I secretion system and contact-dependent inhibition systems. Bap, CDI
23  2017 Structural basis of the interaction between the putative adhesion-involved and iron-regulated FrpD and FrpC proteins of Neisseria meningitidis. ---
24  2017 Structure-Function Relationships Underlying the Capacity of Bordetella Adenylate Cyclase Toxin to Disarm Host Phagocytes. cAMP
25  2017 Zn2+-dependent autocatalytic activity of the Bordetella pertussis CyaA-hemolysin. CyaA-Hly
26  2015 Interdomain Contacts and the Stability of Serralysin Protease from Serratia marcescens. ---
27  2015 Isolated CyaA-RTX subdomain from Bordetella pertussis: Structural and functional implications for its interaction with target erythrocyte membranes. CyaA-Hly, sRBC
28  2015 Kingella kingae: carriage, transmission, and disease. ---
29  2015 Structural models of intrinsically disordered and calcium-bound folded states of a protein adapted for secretion. ---
30  2015 The Bordetella adenylate cyclase repeat-in-toxin (RTX) domain is immunodominant and elicits neutralizing antibodies. ACT
31  2015 The Bordetella adenylate cyclase repeat-in-toxin (RTX) domain is immunodominant and elicits neutralizing antibodies. CORNAME:Hewlett, Erik L [added]; Maynard, Jennifer A [added] ---
32  2014 Boundary region between coexisting lipid phases as initial binding sites for Escherichia coli alpha-hemolysin: a real-time study. BAM, HlyA, Ld
33  2014 Doubling the cross-linking interface of a rationally designed beta roll peptide for calcium-dependent proteinaceous hydrogel formation. MBP
34  2014 Equilibrium folding of pro-HlyA from Escherichia coli reveals a stable calcium ion dependent folding intermediate. T1SS
35  2014 Genetic and phenotypic analysis of Vibrio cholerae non-O1, non-O139 isolated from German and Austrian patients. MARTX, MS, TCP, TTSS
36  2014 Genomics and host specialization of honey bee and bumble bee gut symbionts. ---
37  2014 Hemolysin of enterohemorrhagic Escherichia coli: structure, transport, biological activity and putative role in virulence. EHEC, EHEC-Hly, Ehx, HUS, OMVs
38  2014 Inducible polymerization and two-dimensional assembly of the repeats-in-toxin (RTX) domain from the Pseudomonas aeruginosa alkaline protease. ---
39  2014 Simultaneous detection of antibodies against Apx toxins ApxI, ApxII, ApxIII, and ApxIV in pigs with known and unknown Actinobacillus pleuropneumoniae exposure using a multiplexing liquid array platform. CFT, ELISAs, FMIA
40  2014 Virulence genes in clinical and environmental Stenotrophomas maltophilia isolates: a genome sequencing and gene expression approach. ---
41  2013 A designed, phase changing RTX-based peptide for efficient bioseparations. AdhD, GFP, MBP
42  2013 Aggregatibacter actinomycetemcomitans leukotoxin utilizes a cholesterol recognition/amino acid consensus site for membrane association. CRAC, LFA-1
43  2013 Differences in purinergic amplification of osmotic cell lysis by the pore-forming RTX toxins Bordetella pertussis CyaA and Actinobacillus pleuropneumoniae ApxIA: the role of pore size. PPADS
44  2013 Enterohemorrhagic Escherichia coli hemolysin employs outer membrane vesicles to target mitochondria and cause endothelial and epithelial apoptosis. EHEC, EHEC-Hly, HBMEC, OMVs
45  2013 Molecular crowding stabilizes both the intrinsically disordered calcium-free state and the folded calcium-bound state of a repeat in toxin (RTX) protein. ---
46  2013 Monodisperse and LPS-free Aggregatibacter actinomycetemcomitans leukotoxin: interactions with human beta2 integrins and erythrocytes. SRCD
47  2013 Rearranging and concatenating a native RTX domain to understand sequence modularity. ---
48  2013 Self-assembly of pH and calcium dual-responsive peptide-amphiphilic hydrogel. ---
49  2012 Calcium-induced folding and stabilization of the Pseudomonas aeruginosa alkaline protease. AP
50  2012 Identification of the minimal region in lipase ABC transporter recognition domain of Pseudomonas fluorescens for secretion and fluorescence of green fluorescent protein. EGF, GFP, LARDs, T1SS
51  2012 Leukotoxin from Aggregatibacter actinomycetemcomitans causes shrinkage and P2X receptor-dependent lysis of human erythrocytes. PS
52  2012 Mannheimia haemolytica and its leukotoxin cause macrophage extracellular trap formation by bovine macrophages. LKT, MET, NETs
53  2012 Re-evaluation of a bacterial antifreeze protein as an adhesin with ice-binding activity. AFPs, RII, RIV
54  2012 The repeat-in-toxin family member TosA mediates adherence of uropathogenic Escherichia coli and survival during bacteremia. UPEC, UTI
55  2011 Aggregatibacter actinomycetemcomitans leukotoxin is post-translationally modified by addition of either saturated or hydroxylated fatty acyl chains. ---
56  2011 Aggregatibacter actinomycetemcomitans leukotoxin: a powerful tool with capacity to cause imbalance in the host inflammatory response. ---
57  2011 Bordetella pertussis CyaA-RTX subdomain requires calcium ions for structural stability against proteolytic degradation. CyaA-PF
58  2011 Calcium-induced folding of intrinsically disordered repeat-in-toxin (RTX) motifs via changes of protein charges and oligomerization states. ---
59  2011 Ehrlichia chaffeensis tandem repeat proteins and Ank200 are type 1 secretion system substrates related to the repeats-in-toxin exoprotein family. TRP
60  2011 Influences of ORF1 on the virulence and immunogenicity of Actinobacillus pleuropneumoniae. ---
61  2011 Predicting genetic traits and epitope analysis of apxIVA in Actinobacillus pleuropneumoniae. ---
62  2011 Presence of putative repeat-in-toxin gene tosA in Escherichia coli predicts successful colonization of the urinary tract. UPEC, UTIs
63  2011 Structure and function of MARTX toxins and other large repetitive RTX proteins. ---
64  2010 Bordetella adenylate cyclase toxin promotes calcium entry into both CD11b+ and CD11b- cells through cAMP-dependent L-type-like calcium channels. ACT
65  2010 Calcium-induced folding and stabilization of the intrinsically disordered RTX domain of the CyaA toxin. RD
66  2010 Characterization of the regions involved in the calcium-induced folding of the intrinsically disordered RTX motifs from the bordetella pertussis adenylate cyclase toxin. RD
67  2010 Crystallization and preliminary crystallographic characterization of the iron-regulated outer membrane lipoprotein FrpD from Neisseria meningitidis. FrpD, SeMet FrpD43-271
68  2010 RTX proteins: a highly diverse family secreted by a common mechanism. ---
69  2009 A FRET-based method for probing the conformational behavior of an intrinsically disordered repeat domain from Bordetella pertussis adenylate cyclase. FRET
70  2009 Regulation of the type I protein secretion system by the MisR/MisS two-component system in Neisseria meningitidis. EMSA
71  2009 RTX calcium binding motifs are intrinsically disordered in the absence of calcium: implication for protein secretion. RD
72  2009 Vesicular stabilization and activity augmentation of enterohaemorrhagic Escherichia coli haemolysin. OMVs
73  2008 A Ca2+-dependent bacterial antifreeze protein domain has a novel beta-helical ice-binding fold. ---
74  2008 Cloning and characterization of a novel cysteine protease gene (HbCP1) from Hevea brasiliensis. GRAN, RACE
75  2007 Aggregatibacter actinomycetemcomitans leukotoxin requires beta-sheets 1 and 2 of the human CD11a beta-propeller for cytotoxicity. LFA-1, Ltx
76  2007 Human CD18 is the functional receptor for Aggregatibacter actinomycetemcomitans leukotoxin. LFA-1
77  2007 The TolC-like protein of neisseria meningitidis is required for extracellular production of the repeats-in-toxin toxin FrpC but not for resistance to antimicrobials recognized by the Mtr efflux pump system. ---
78  2006 Bordetella adenylate cyclase toxin: a swift saboteur of host defense. ---
79  2006 Identification of an RTX determinant of Burkholderia cenocepacia J2315 by subtractive hybridization. ---
80  2006 Purification and characterization of a hemolysin-like protein, Sll1951, a nontoxic member of the RTX protein family from the Cyanobacterium Synechocystis sp. strain PCC 6803. GT, HLP
81  2005 The CD11a partner in Sus scrofa lymphocyte function-associated antigen-1 (LFA-1): mRNA cloning, structure analysis and comparison with mammalian homologues. LFA-1
82  2005 The Escherichia coli Hemolysin. ---
83  2005 Unusual genetic organization of a functional type I protein secretion system in Neisseria meningitidis. TOSS
84  2004 A novel "clip-and-link" activity of repeat in toxin (RTX) proteins from gram-negative pathogens. Covalent protein cross-linking by an Asp-Lys isopeptide bond upon calcium-dependent processing at an Asp-Pro bond. ---
85  2003 Genetic and biochemical characterization of PrtA, an RTX-like metalloprotease from Photorhabdus. INH
86  2003 Gram-negative bacterial ATP-binding cassette protein exporter family and diverse secretory proteins. ABC
87  2002 The contribution of accessory toxins of Vibrio cholerae O1 El Tor to the proinflammatory response in a murine pulmonary cholera model. HapA, IL, MIP
88  2000 In vivo covalent cross-linking of cellular actin by the Vibrio cholerae RTX toxin. ---
89  1999 Epitope mapping of monoclonal antibodies against Bordetella pertussis adenylate cyclase toxin. AC, mAbs
90  1999 Lipopolysaccharide complexes with Pasteurella haemolytica leukotoxin. CCS, LKT, LPS, SDS-PAGE, SDS-PAGE LKT
91  1998 Actinobacillus actinomycetemcomitans leukotoxin induces apoptosis in HL-60 cells. Ltx
92  1996 Pore-forming properties of the plasmid-encoded hemolysin of enterohemorrhagic Escherichia coli O157:H7. EHEC
93  1994 Identification and immunological characterization of the domain of Actinobacillus actinomycetemcomitans leukotoxin that determines its specificity for human target cells. ---