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■ Abbreviation / Long Form : SN / substantia nigra

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Abbreviation:   SN  (>> Co-occurring Abbreviation)
Long Form:   substantia nigra
 Abbreviation Variation
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No. Year Title Co-occurring Abbreviation
2019 3D texture analyses within the substantia nigra of Parkinson's disease patients on quantitative susceptibility maps and R2∗ maps. HC, PD, QSM
2019 5-(3,4-Difluorophenyl)-3-(6-methylpyridin-3-yl)-1,2,4-oxadiazole (DDO-7263), a novel Nrf2 activator targeting brain tissue, protects against MPTP-induced subacute Parkinson's disease in mice by inhibiting the NLRP3 inflammasome and protects PC12 cells against oxidative stress. MPTP, PD, TH, THP-Ms
2019 7,8-Dihydroxyflavone Protects Nigrostriatal Dopaminergic Neurons from Rotenone-Induced Neurotoxicity in Rodents. 7,8-DHF, PD
2019 Acupuncture Inhibits the Increase in Alpha-Synuclein by Modulating SGK1 in an MPTP Induced Parkinsonism Mouse Model. MPTP, PD, SGK1
2019 Aggravated behavioral and neurochemical deficits and redox imbalance in mice with enhanced neonatal iron intake: improvement by biochanin A and role of microglial p38 activation. MAPK, MPTP
2019 alpha-Synuclein Expression Is Preserved in Substantia Nigra GABAergic Fibers of Young and Aged Neurotoxin-Treated Rhesus Monkeys. alpha-syn, MPTP, PD, TH
2019 Ameliorative Effect of Withaferin A on Ageing-Mediated Impairment in the Dopamine System and Its Associated Behavior of Wistar Albino Rat. DA, HVA, ST
2019 Amphetamine Self-Administration and Its Extinction Alter the 5-HT1B Receptor Protein Levels in Designated Structures of the Rat Brain. GP, HIP, NAc, VTA
2019 Astrocyte support is important for the compensatory potential of the nigrostriatal system neurons during early neurodegeneration. AMPK, FC, PGC-1alpha
10  2019 Beneficial effects of n-3 polyunsaturated fatty acids administration in a partial lesion model of Parkinson's disease: The role of glia and NRf2 regulation. DHA, PD
11  2019 Beneficial effects of trehalose on striatal dopaminergic deficits in rodent and primate models of synucleinopathy in Parkinson's disease. PD
12  2019 Central neuropeptide-S treatment improves neurofunctions of 6-OHDA-induced Parkinsonian rats. 4-HNE, NPS, NPSR, PD, TH
13  2019 Characterization of Brain Lysosomal Activities in GBA-Related and Sporadic Parkinson's Disease and Dementia with Lewy Bodies. DLB, GCase, PD
14  2019 Combined Visualization of Nigrosome-1 and Neuromelanin in the Substantia Nigra Using 3T MRI for the Differential Diagnosis of Essential Tremor and de novo Parkinson's Disease. AUC, ET, NM-MRI, PD, QSM, ROC
15  2019 CRISPR/Cas9 Editing of Glia Maturation Factor Regulates Mitochondrial Dynamics by Attenuation of the NRF2/HO-1 Dependent Ferritin Activation in Glial Cells. COX2, CRISPR, GMF, HO-1, NOS2, Nrf2, PD
16  2019 Disrupted reinforcement learning during post-error slowing in ADHD. TD
17  2019 Dopamine neuronal protection in the mouse Substantia nigra by GHSR is independent of electric activity. DREADD, MPTP, PD
18  2019 Dose-Dependent Neuroprotective Effect of Standardized Bee Venom Phospholipase A2 Against MPTP-Induced Parkinson's Disease in Mice. BV, GMP, PD, Th1
19  2019 Downregulation of tyrosine hydroxylase phenotype after AAV injection above substantia nigra: Caution in experimental models of Parkinson's disease. AAV, DIO ORF, GFP, TH
20  2019 Effect of Age on Substantia Nigra Hyper-echogenicity in Parkinson's Disease Patients and Healthy Controls. PD
21  2019 Effects of agomelatine in rotenone-induced Parkinson's disease in rats. PD
22  2019 Expression of Dopamine Receptors in the Lateral Hypothalamic Nucleus and Their Potential Regulation of Gastric Motility in Rats With Lesions of Bilateral Substantia Nigra. ChAT, DMV, DR, GI, IR, LH, OX1R, OXA, PD
23  2019 Fishing for Parkinson's Disease: A review of the literature. PD
24  2019 Functional connectivity disruption of the substantia nigra associated with cognitive impairment in acute mild traumatic brain injury. ---
25  2019 Gastrointestinal non-motor dysfunction in Parkinson's disease model rats with 6-hydroxydopamine. PD
26  2019 Gene co-expression analysis of the human substantia nigra identifies BMP2 as a neurotrophic factor that can promote neurite growth in cells overexpressing wild-type or A53T alpha-synuclein. BMP, VM
27  2019 Genetic suppression of IKK2/NF-kappaB in astrocytes inhibits neuroinflammation and reduces neuronal loss in the MPTP-Probenecid model of Parkinson's disease. MPTPp, NF-kappaB, PD
28  2019 Glucocorticoid receptor in astrocytes regulates midbrain dopamine neurodegeneration through connexin hemichannel activity. DN, GR, MPTP, PD
29  2019 High-Spatial-Resolution Diffusion MRI in Parkinson Disease: Lateral Asymmetry of the Substantia Nigra. ADC, CTRW, HC, PD, ROC
30  2019 Hydralazine Protects Nigrostriatal Dopaminergic Neurons From MPP+ and MPTP Induced Neurotoxicity: Roles of Nrf2-ARE Signaling Pathway. ARE, HYD, MPTP, Nrf2, PD
31  2019 Hypertrophy of nigral neurons in Torsin1A deletion (DYT1) carriers manifesting dystonia. ---
32  2019 Ibogaine Administration Modifies GDNF and BDNF Expression in Brain Regions Involved in Mesocorticolimbic and Nigral Dopaminergic Circuits. BDNF, GDNF, NAcc, NFs, NGF, PFC, VTA
33  2019 Impact of Dopamine Oxidation on Dopaminergic Neurodegeneration. DA, DAergic, PD
34  2019 Increased iron deposition of deep cerebral gray matter structures in hemodialysis patients: A longitudinal study using quantitative susceptibility mapping. CN, DN, FDR, GP, HCs, MMSE, PT, PUT, QSM, RN, SWI, THA
35  2019 Induction of typical and atypical neurogenesis in the adult substantia nigra after mouse embryonic stem cells transplantation. EBCs, NPCs
36  2019 Iron quantification in Parkinson's disease using an age-based threshold on susceptibility maps: The advantage of local versus entire structure iron content measurements. IPD, QSM, RII, RN
37  2019 Iron-related nigral degeneration influences functional topology mediated by striatal dysfunction in Parkinson's disease. PD
38  2019 Is hyperhomocysteinemia associated with the structural changes of the substantia nigra in Parkinson's disease? A two-year follow-up study. DKI, HHcy, MK, PD, SSLI
39  2019 L-alpha-aminoadipic acid restricts dopaminergic neurodegeneration and motor deficits in an inflammatory model of Parkinson's disease in male rats. L-AAA, LPS, PD
40  2019 Long-term challenge of methylphenidate changes the neuronal population and membrane property of dopaminergic neuron in rats. ADHD
41  2019 Low-Dose Maraviroc, an Antiretroviral Drug, Attenuates the Infiltration of T Cells into the Central Nervous System and Protects the Nigrostriatum in Hemiparkinsonian Monkeys. PD
42  2019 Magnetic resonance imaging, susceptibility weighted imaging and quantitative susceptibility mapping findings of pantothenate kinase-associated neurodegeneration. GP, MRI, PKAN, QSM, RN, SWI
43  2019 Minocycline Protects against Rotenone-Induced Neurotoxicity Correlating with Upregulation of Nurr1 in a Parkinson's Disease Rat Model. CREB, NO, PD, ROS, TH
44  2019 Modulation by chronic antipsychotic administration of PKA- and GSK3beta-mediated pathways and the NMDA receptor in rat ventral midbrain. D2R, VTA
45  2019 Motor Improvement-Related Regional Cerebral Blood Flow Changes in Parkinson's Disease in Response to Antiparkinsonian Drugs. LG, MG, PD, rCBF, SPECT
46  2019 MPTP-driven NLRP3 inflammasome activation in microglia plays a central role in dopaminergic neurodegeneration. MPTP, PD
47  2019 Neurodegeneration of the Substantia Nigra after Ipsilateral Infarct: MRI R2* Mapping and Relationship to Clinical Outcome. ---
48  2019 Neuromelanin-sensitive MRI as a noninvasive proxy measure of dopamine function in the human brain. NM, NM-MRI
49  2019 Neuroprotective Effect of Echinacoside in Subacute Mouse Model of Parkinson's Disease. DA, ELISA, GDNF, GFAP, Iba-1, MPTP, PD, SNpc, TH, VTA
50  2019 Neuroprotective effects of Tat-ATOX1 protein against MPP+-induced SH-SY5Y cell deaths and in MPTP-induced mouse model of Parkinson's disease. ATOX1, MAPKs, MPTP, PD
51  2019 NLRP3 inflammasome pathway is involved in olfactory bulb pathological alteration induced by MPTP. GFAP, IL-1beta, MPTP, NLRP3, PD, TH, TLR4
52  2019 NMDA receptor modulation of the pedunculopontine tegmental nucleus underlies the motivational drive for feeding induced by midbrain dopaminergic neurons. PPN, VTA
53  2019 Paraquat exposure increases oxidative stress within the dorsal striatum of male mice with a genetic deficiency in one-carbon metabolism. 5-methylTHF, MTHFR, PD
54  2019 Partial depletion of dopaminergic neurons in the substantia nigra impairs olfaction and alters neural activity in the olfactory bulb. OB, PD
55  2019 Predictive model of spread of Parkinson's pathology using network diffusion. NDM, PD
56  2019 Pro-apoptotic effects of low doses of dimethoate in rat brain. CX, cyt c, DMT
57  2019 Regional morphometric abnormalities and clinical relevance in Wilson's disease. ---
58  2019 Semaglutide is Neuroprotective and Reduces alpha-Synuclein Levels in the Chronic MPTP Mouse Model of Parkinson's Disease. GLP-1, PD, TH
59  2019 siRNA-mediated knockdown of B3GALT4 decreases GM1 ganglioside expression and enhances vulnerability for neurodegeneration. PD
60  2019 Sophora Tomentosa Extract Prevents MPTP-Induced Parkinsonism in C57BL/6 Mice Via the Inhibition of GSK-3beta Phosphorylation and Oxidative Stress. ABTS, GSK3-beta, MDA, MPTP, TH
61  2019 Stimulation of noradrenergic transmission by reboxetine is beneficial for a mouse model of progressive parkinsonism. LC, PD, VTA
62  2019 Systemic Inflammation Changes the Site of RAGE Expression from Endothelial Cells to Neurons in Different Brain Areas. CB, HIPP, PFC, RAGE
63  2019 The effects of rotenone on TH, BDNF and BDNF-related proteins in the brain and periphery: Relevance to early Parkinson's disease. BDNF, PD, TH
64  2019 The influence of Parkinson's disease on the functional connectivity of the motor loop of human basal ganglia. BG, PD, PUT, STN, Tal
65  2019 The usual suspects, dopamine and alpha-synuclein, conspire to cause neurodegeneration. PD
66  2019 Therapeutic efficacy of glial cell-derived neurotrophic factor loaded collagen scaffolds in ex vivo organotypic brain slice Parkinson's disease models. 6-OHDA, GDNF, PD, TH
67  2019 Tyrosine Hydroxylase Inhibition in Substantia Nigra Decreases Movement Frequency. AMPT, DA, TH
68  2018 1-Methyl-4-phenyl-1,2,3,6 tetrahydropyridine/probenecid impairs intestinal motility and olfaction in the early stages of Parkinson's disease in mice. MPTP, PD
69  2018 2,5-Hexanedione induces dopaminergic neurodegeneration through integrin alphaMbeta2/NADPH oxidase axis-mediated microglial activation. HD, NOX2, PD
70  2018 A meta-analysis of diffusion tensor imaging of substantia nigra in patients with Parkinson's disease. DTI, HCs, PD
71  2018 A meta-analysis of public microarray data identifies biological regulatory networks in Parkinson's disease. DEGs, lncRNA, PD, SNP
72  2018 A New Hope for a Devastating Disease: Hydrogen Sulfide in Parkinson's Disease. CO, NMDA, NO, PD
73  2018 Abnormal Resting-State Connectivity in a Substantia Nigra-Related Striato-Thalamo-Cortical Network in a Large Sample of First-Episode Drug-Naive Patients With Schizophrenia. FC, fMRI, SCZ
74  2018 Abnormal ventral tegmental area-anterior cingulate cortex connectivity in Parkinson's disease with depression. ACC, DPD, HC, NDPD, PD, PET, SPECT, VTA
75  2018 Abrogation of the Circadian Nuclear Receptor REV-ERBalpha Exacerbates 6-Hydroxydopamine-Induced Dopaminergic Neurodegeneration. DAergic, PD
76  2018 Activation of Nigrostriatal Dopamine Neurons during Fear Extinction Prevents the Renewal of Fear. DA, DS, Gq-DREADD
77  2018 Aging-Related Overactivity of the Angiotensin/AT1 Axis Decreases Sirtuin 3 Levels in the Substantia Nigra, which Induces Vulnerability to Oxidative Stress and Neurodegeneration. Ang II, AT1, SIRT3
78  2018 Alpha-synuclein overexpression in the olfactory bulb initiates prodromal symptoms and pathology of Parkinson's disease. CPu, HIP, LB, OB, PD, PFC, pSer129, ThS
79  2018 Altered expression of genes involved in ganglioside biosynthesis in substantia nigra neurons in Parkinson's disease. PD
80  2018 Altered serotonergic and GABAergic neurotransmission in a mice model of obsessive-compulsive disorder. AM, GP, HPC, NAc, OCD, VTA
81  2018 An Easy-to-Implement Protocol for Preparing Postnatal Ventral Mesencephalic Cultures. ---
82  2018 Anacardic Acids from Cashew Nuts Prevent Behavioral Changes and Oxidative Stress Induced by Rotenone in a Rat Model of Parkinson's Disease. AAs, T-SOD
83  2018 Anatomical Templates of the Midbrain Ventral Tegmental Area and Substantia Nigra for Asian Populations. ROIs, rs-fMRI, VTA
84  2018 Association of exposure to manganese and iron with relaxation rates R1 and R2*- magnetic resonance imaging results from the WELDOX II study. FL, GP, HC, Mn, MnB, PD, SF
85  2018 Auricular Vagus Nerve Stimulation Exerts Antiinflammatory Effects and Immune Regulatory Function in a 6-OHDA Model of Parkinson's Disease. alpha7 nAChRs, aVNS, IL-1beta, PD, TH, Th, Treg
86  2018 Automated segmentation of midbrain structures with high iron content. FLAIR, QSM, RN, STN
87  2018 Brain iron deposition in type 2 diabetes mellitus with and without mild cognitive impairment-an in vivo susceptibility mapping study. CN, HP, MCI, PU, QSM, T2DM
88  2018 Brain Mitochondria, Aging, and Parkinson's Disease. mtDNA, PD
89  2018 Cannabinoid CB1 and CB2Receptors, and Monoacylglycerol Lipase Gene Expression Alterations in the Basal Ganglia of Patients with Parkinson's Disease. MAGL, PD, PLA, PUT, RIN
90  2018 Cell-Specific RNA Quantification in Human SN DA Neurons from Heterogeneous Post-mortem Midbrain Samples by UV-Laser Microdissection and RT-qPCR. DA, PD, RT-qPCR, UV-LMD
91  2018 Chronic stress-induced gut dysfunction exacerbates Parkinson's disease phenotype and pathology in a rotenone-induced mouse model of Parkinson's disease. DA, LPS, PD, RS
92  2018 Circadian and Homeostatic Modulation of Multi-Unit Activity in Midbrain Dopaminergic Structures. DA, EEG, VTA
93  2018 Clinical features and dysfunctions of iron metabolism in Parkinson disease patients with hyper echogenicity in substantia nigra: a cross-sectional study. CSF, MS, NMS, PD
94  2018 Comparison of Administration Routes on the Protective Effects of Bee Venom Phospholipase A2 in a Mouse Model of Parkinson's Disease. PD, s.c, TH
95  2018 CRISPR/Cas9-Mediated Generation of Guangxi Bama Minipigs Harboring Three Mutations in alpha-Synuclein Causing Parkinson's Disease. PD, SCNT
96  2018 Curcumin affords neuroprotection and inhibits alpha-synuclein aggregation in lipopolysaccharide-induced Parkinson's disease model. AAS, iNOS, LBs, PD
97  2018 Decreased expression of serum- and glucocorticoid-inducible kinase 1 (SGK1) promotes alpha-synuclein increase related with down-regulation of dopaminergic cell in the Substantia Nigra of chronic MPTP-induced Parkinsonism mice and in SH-SY5Y cells. alpha-syn, MPTP, PD, SGK1
98  2018 Defective mitochondrial protein import contributes to complex I-induced mitochondrial dysfunction and neurodegeneration in Parkinson's disease. pc, PD
99  2018 Deletion of Kir6.2/SUR1 potassium channels rescues diminishing of DA neurons via decreasing iron accumulation in PD. DA, FTL, MPTP, PD, SUR1
100  2018 Diagnosis of Early-Stage Idiopathic Parkinson's Disease Using High-Resolution Quantitative Susceptibility Mapping Combined with Histogram Analysis in the Substantia Nigra at 3 T. IPD, QSM, ROIs, SMWI