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■ Abbreviation / Long Form : Tiam1 / T lymphoma invasion and metastasis 1

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Total Number of Papers: 60
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Abbreviation:   Tiam1  (>> Co-occurring Abbreviation)
Long Form:   T lymphoma invasion and metastasis 1
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No. Year Title Co-occurring Abbreviation
2019 CBFbeta/RUNX3-miR10b-TIAM1 molecular axis inhibits proliferation, migration, and invasion of gastric cancer cells. CBFbeta, GC
2019 Diagnostic Value of miR-142-5p and Tiam-1 in Colon Cancer Patients. ---
2019 High Tiam1 expression predicts positive lymphatic metastasis and worse survival in patients with malignant solid tumors: a systematic review and meta-analysis. OR
2019 Tiam1 high expression is associated with poor prognosis in solid cancers: A meta-analysis. CNKI, DFS, HRs, OS
2018 Altered expression of TIAM1 in endotoxin-challenged airway epithelial cells and rodent septic models. ALI, HTBEs, LPS
2018 Elevated expression of Tiam1 is associated with poor prognosis and promotes tumor progression in pancreatic cancer. PC, PDAC
2018 miR-10b Downregulated by DNA Methylation Acts as a Tumor Suppressor in HPV-Positive Cervical Cancer via Targeting Tiam1. CC, miRNAs, TFAP2A
2018 The CircRNA-ACAP2/Hsa-miR-21-5p/ Tiam1 Regulatory Feedback Circuit Affects the Proliferation, Migration, and Invasion of Colon Cancer SW480 Cells. circRNAs, miRNA
2018 The inhibition of the effect and mechanism of vascular intimal hyperplasia in Tiam1 knockout mice. HASMCs
10  2018 Upregulation of Tiam1 contributes to cervical cancer disease progression and indicates poor survival outcome. IHC, LN, OS
11  2017 The prognostic value of T Lymphoma Invasion and Metastasis 1 (TIAM1) expression in oral squamous cell carcinoma. OSCC
12  2017 The Tiam1 guanine nucleotide exchange factor is auto-inhibited by its pleckstrin homology coiled-coil extension domain. DH-PHc, GEF, PHn-CC-Ex
13  2017 TIAM1 inhibits lung fibroblast differentiation in pulmonary fibrosis. BLM, IPF, NF, SMA, TGF-beta
14  2016 Clinical implication of Tiam1 overexpression in the prognosis of patients with serous ovarian carcinoma. OS
15  2016 Clinicopathological implications of Tiam1 overexpression in invasive ductal carcinoma of the breast. DCIS, DFS, IF, IHC, OS
16  2015 An EGFR/PI3K/AKT axis promotes accumulation of the Rac1-GEF Tiam1 that is critical in EGFR-driven tumorigenesis. EGFR
17  2015 By downregulating TIAM1 expression, microRNA-329 suppresses gastric cancer invasion and growth. GC, miRNAs
18  2015 JAM-A promotes wound healing by enhancing both homing and secretory activities of mesenchymal stem cells. JAM-A, MSCs, TFs
19  2015 MicroRNA-377 suppresses cell proliferation and invasion by inhibiting TIAM1 expression in hepatocellular carcinoma. HCC, miRNAs
20  2015 Overexpression of Tiam1 promotes the progression of laryngeal squamous cell carcinoma. LSCC
21  2015 The prognostic value of Tiam1 protein expression in head and neck squamous cell carcinoma: a retrospective study. DFS, HNSCC, OS
22  2015 The sirtuins promote Dishevelled-1 scaffolding of TIAM1, Rac activation and cell migration. Dvl, GEF, SIRT1
23  2014 5-Lipoxygenase and cysteinyl leukotriene receptor 1 regulate epidermal growth factor-induced cell migration through Tiam1 upregulation and Rac1 activation. 5-LOX, CysLT1, EGF, LTC4
24  2014 Elevated expression of T-lymphoma invasion and metastasis inducing factor 1 in squamous-cell carcinoma of the head and neck and its clinical significance. SCCHN
25  2014 MiR-141 suppresses the migration and invasion of HCC cells by targeting Tiam1. HCC, ISH, miRNA
26  2014 miR-29b suppresses tumor growth and metastasis in colorectal cancer via downregulating Tiam1 expression and inhibiting epithelial-mesenchymal transition. CRC, EMT
27  2014 Overexpression of Tiam1 is associated with malignant phenotypes of nasopharyngeal carcinoma. NPC, RT-PCR
28  2013 Inhibition of Rac1 promotes BMP-2-induced osteoblastic differentiation. BMP-2, Cdc42, Rac1, Rho, ROCK
29  2013 MiR-29c suppresses invasion and metastasis by targeting TIAM1 in nasopharyngeal carcinoma. NPC
30  2013 miRNA-218 inhibits osteosarcoma cell migration and invasion by down-regulating of TIAM1, MMP2 and MMP9. MMP2
31  2013 miRNA-22 suppresses colon cancer cell migration and invasion by inhibiting the expression of T-cell lymphoma invasion and metastasis 1 and matrix metalloproteinases 2 and 9. miR-22, VEGF
32  2013 NMDA receptor couples Rac1-GEF Tiam1 to direct oligodendrocyte precursor cell migration. CNS, NMDA, OPCs, Rac1-GEF
33  2013 Optogenetic inhibition of D1R containing nucleus accumbens neurons alters cocaine-mediated regulation of Tiam1. MSNs, NAc
34  2013 The Rac-GAP Bcr is a novel regulator of the Par complex that controls cell polarity. Bcr, GAP
35  2013 Thyroid hormone regulation of miR-21 enhances migration and invasion of hepatoma. miR-21
36  2013 Tiam1 is associated with hepatocellular carcinoma metastasis. HCC
37  2013 Tiam1 transgenic mice display increased tumor invasive and metastatic potential of colorectal cancer after 1,2-dimethylhydrazine treatment. CRC, DMH, i.p, IHC
38  2012 CtBP2 Promotes Human Cancer Cell Migration by Transcriptional Activation of Tiam1. ARF, CtBPs, GEF, KLF8, PI3K, RNAi
39  2012 Expression of Tiam1 in lung cancer and its clinical significance. PU, TNM
40  2012 Tiam1, overexpressed in most malignancies, is a novel tumor biomarker. GNEF, TMA
41  2011 Aberrant calcium/calmodulin-dependent protein kinase II (CaMKII) activity is associated with abnormal dendritic spine morphology in the ATRX mutant mouse brain. CaMKII, GEFs, mPFC, PAKs, PP1
42  2011 Overexpression of T lymphoma invasion and metastasis 1 predict renal cell carcinoma metastasis and overall patient survival. RCC
43  2011 Overexpression of Tiam1 predicts poor prognosis in patients with esophageal squamous cell carcinoma. ESCC
44  2011 The molecular basis of the Caskin1 and Mint1 interaction with CASK. CASK
45  2011 [Quantitative analysis of Tiam1 expression in lung cancer and its clinical significance]. ---
46  2010 The Tiam1 PDZ domain couples to Syndecan1 and promotes cell-matrix adhesion. GEF
47  2010 Up-regulation of Tiam1 and Rac1 correlates with poor prognosis in hepatocellular carcinoma. ---
48  2009 Mutated K-ras(Asp12) promotes tumourigenesis in Apc(Min) mice more in the large than the small intestines, with synergistic effects between K-ras and Wnt pathways. beta-NF, COX-2, MAPK, MMP7, pErk, PP1A, PPARd, VEGF
49  2009 Overexpression of Tiam1 in hepatocellular carcinomas predicts poor prognosis of HCC patients. HCC
50  2009 Progression of breast tumors is accompanied by a decrease in expression of the Rho guanine exchange factor Tiam1. ER, GEF, PR, Rho, uPA
51  2009 [Correlation between T lymphoma invasion and metastasis 1 expression and epithelial-mesenchymal transition in human colorectal carcinomas]. CRC, EMT
52  2009 [Expression of Tiam1 in breast carcinomas and its clinical significance]. RT-PCR
53  2008 The role of T-lymphoma invasion and metastasis inducing protein 1 in early pregnancy in mice. ---
54  2007 16-kDa prolactin inhibits endothelial cell migration by down-regulating the Ras-Tiam1-Rac1-Pak1 signaling pathway. 16k PRL, PAK1, RAEC
55  2006 Lentivirus-mediated silencing of Tiam1 gene influences multiple functions of a human colorectal cancer cell line. RNAi
56  2005 The guanine nucleotide exchange factor Tiam1 increases colon carcinoma growth at metastatic sites in an orthotopic nude mouse model. ---
57  2005 [Correlation between expression of the Tiam1 gene and the invasion and metastasis in nasopharyngeal carcinoma]. RT-PCR
58  2003 [Significance of expression of T lymphoma invasion/metastasis gene in ovarian cancer cells]. ---
59  2000 Crystal structure of Rac1 in complex with the guanine nucleotide exchange region of Tiam1. DH, PH
60  1997 The guanine nucleotide exchange factor Tiam1 affects neuronal morphology; opposing roles for the small GTPases Rac and Rho. GEF