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■ Abbreviation / Long Form : mAChR / muscarinic acetylcholine receptor

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Total Number of Papers: 722
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Abbreviation:   mAChR  (>> Co-occurring Abbreviation)
Long Form:   muscarinic acetylcholine receptor
 Abbreviation Variation
 Long Form Variation
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No. Year Title Co-occurring Abbreviation
2020 Blockade of muscarinic acetylcholine receptor by scopolamine impairs the memory formation of filial imprinting in domestic chicks (Gallus Gallus domesticus). IMM, M1 receptor
2020 Crosstalk between the M1 muscarinic acetylcholine receptor and the endocannabinoid system: A relevance for Alzheimer's disease? AD
2020 Possible interaction between the ventral hippocampal cannabinoid CB2 and muscarinic acetylcholine receptors on the modulation of memory consolidation in mice. ---
2019 6-Phenylpyrimidin-4-ones as Positive Allosteric Modulators at the M1 mAChR: The Determinants of Allosteric Activity. ACh, PAM
2019 Acetylcholine-treated murine dendritic cells promote inflammatory lung injury. ACh, DC
2019 Anti-inflammatory and antioxidant effects of muscarinic acetylcholine receptor (mAChR) activation in the rat hippocampus. CRS, OXO, ROS, SOD
2019 Antinociceptive Effect of Spirocyclopiperazinium Salt Compound DXL-A-24 and the Underlying Mechanism. CaMKIIalpha, CGRP, CREB, DRGs, MWT, nAChR, PWL, TNF-alpha
2019 Cholinergic Signaling Alters Stress-Induced Sensitization of Hippocampal Contextual Learning. ACh, DH, PTSD, SEFL
2019 Cracking the Betel Nut: Cholinergic Activity of Areca Alkaloids and Related Compounds. nAChR, nAChR
10  2019 Cryptic pocket formation underlies allosteric modulator selectivity at muscarinic GPCRs. GPCR, PAMs
11  2019 Crystal structure of the M5 muscarinic acetylcholine receptor. ---
12  2019 Discovery of Selective M4 Muscarinic Acetylcholine Receptor Agonists with Novel Carbamate Isosteres. ---
13  2019 Effects of Muscarinic Acetylcholine m1 and m4 Receptor Blockade on Dyskinesia in the Hemi-Parkinsonian Rat. LID, PD
14  2019 Elucidating Critical Proteinopathic Mechanisms and Potential Drug Targets in Neurodegeneration. A2A, AChE, CJD, GDNF, LRRK2, NMDAR
15  2019 Evaluating Cholinergic Receptor Expression in Guinea Pig Primary Auditory and Rostral Belt Cortices After Noise Damage Using [3H]Scopolamine and [18F]Flubatine Autoradiography. nAChR, RB
16  2019 Evaluation of 11C-LSN3172176 as a Novel PET Tracer for Imaging M1 Muscarinic Acetylcholine Receptors in Nonhuman Primates. ---
17  2019 Fragment-Based Computational Method for Designing GPCR Ligands. beta-AR, CIPs, GPCRs
18  2019 Invasiveness-triggered state transition in malignant melanoma cells. EMT, ITST, p75NTR, siRNA
19  2019 M1 Muscarinic Receptors Modulate Fear-Related Inputs to the Prefrontal Cortex: Implications for Novel Treatments of Posttraumatic Stress Disorder. PFC
20  2019 Muscarinic acetylcholine receptor expression in brain and immune cells of Oreochromis niloticus. ACh
21  2019 Muscarinic acetylcholine receptor signaling generates OFF selectivity in a simple visual circuit. ---
22  2019 Muscarinic agonist, ()-quinuclidin-3-yl-(4-fluorophenethyl)(phenyl)carbamate: High affinity, but low subtype selectivity for human M1 - M5 muscarinic acetylcholine receptors. CHO
23  2019 Parasympathectomy increases resting secretion of the submandibular gland in minipigs in the long term. AQP5, SMG
24  2019 Phencynonate S-isomer as a eutomer is a novel central anticholinergic drug for anti-motion sickness. ---
25  2019 Spicatoside A in red Liriopeplatyphylla displays a laxative effect in a constipation rat model via regulating mAChRs and ER stress signaling. ER, Lop, pRISMCs, SD
26  2019 Targeting Muscarinic Acetylcholine Receptors for the Treatment of Psychiatric and Neurological Disorders. AD
27  2019 The Muscarinic Acetylcholine Receptor M5: Therapeutic Implications and Allosteric Modulation. NAMs, PAMs
28  2018 Administration of muscarinic antagonists induce changes in passive avoidance learning and in synaptic transmission in the CA1 area of the hippocampus. fEPSP
29  2018 Bitopic Binding Mode of an M1 Muscarinic Acetylcholine Receptor Agonist Associated with Adverse Clinical Trial Outcomes. ---
30  2018 Cognitive enhancement and antipsychotic-like activity following repeated dosing with the selective M4 PAM VU0467154. NMDAR, PAMs
31  2018 Discovery and Development of Muscarinic Acetylcholine M4 Activators as Promising Therapeutic Agents for CNS Diseases. ---
32  2018 Discovery and Optimization of Potent and CNS Penetrant M5-Preferring Positive Allosteric Modulators Derived from a Novel, Chiral N-(Indanyl)piperidine Amide Scaffold. PAM
33  2018 Discovery of N-Alkyl Piperazine Side Chain Based CXCR4 Antagonists with Improved Drug-like Properties. ---
34  2018 Disinhibition of CA1 pyramidal cells by low-dose ketamine and other antagonists with rapid antidepressant efficacy. NMDAR
35  2018 Early changes in M2 muscarinic acetylcholine receptors (mAChRs) induced by sarin intoxication may be linked to long lasting neurological effects. mAChRs
36  2018 Effect of green flickering light on myopia development and expression of M1 muscarinic acetylcholine receptor in guinea pigs. RT-PCR
37  2018 GABA-enriched fermented Laminaria japonica improves cognitive impairment and neuroplasticity in scopolamine- and ethanol-induced dementia model mice. ACh, AChE, ALT, AST, CON, CREB, DPZ, EtOH, FL, MWM, PA, SCO, TC, TG
38  2018 Heat shock protein (Hsp) regulation by muscarinic acetylcholine receptor (mAChR) activation in the rat hippocampus. HSF1, HSP
39  2018 Inhibition of ZERO-BK by PKC is involved in carbachol-induced enhancement of rat colon smooth muscle motility. CSM, GI, PKC, PMA
40  2018 Muscarinic M5 receptors modulate ethanol seeking in rats. AUDs, DL
41  2018 Myopia-Inhibiting Concentrations of Muscarinic Receptor Antagonists Block Activation of Alpha2A-Adrenoceptors In Vitro. cM4, hADRA2A, MT3
42  2018 Pharmacological properties of revefenacin (TD-4208), a novel, nebulized long-acting, and lung selective muscarinic antagonist, at human recombinant muscarinic receptors and in rat, guinea pig, and human isolated airway tissues. ACh, COPD
43  2018 Possible anti-inflammatory role of Zingiberis processum rhizoma, one component of the Kampo formula daikenchuto, against neutrophil infiltration through muscarinic acetylcholine receptor activation. 5-HT4R, alpha7nAChR, DKT, EC, IM, KO, POI, TRPA1, ZPR
44  2018 Selective inhibition of M5 muscarinic acetylcholine receptors attenuates cocaine self-administration in rats. CUD, NAM
45  2018 The Anti-Inflammatory Effects of Fermented Herbal Roots of Asparagus cochinchinensis in an Ovalbumin-Induced Asthma Model. AChE, LPS, OVA, ROS
46  2018 The combination of Cassia obtusifolia L. and Foeniculum vulgare M. exhibits a laxative effect on loperamide-induced constipation of rats. Lop
47  2017 Anxiolytic effects of muscarinic acetylcholine receptors agonist oxotremorine in chronically stressed rats and related changes in BDNF and FGF2 levels in the hippocampus and prefrontal cortex. BDNF, CRS, FGF-2, OXO
48  2017 Classics in Chemical Neuroscience: Xanomeline. AD, DMPK
49  2017 Decreased interaction between ZO-1 and occludin is involved in alteration of tight junctions in transplanted epiphora submandibular glands. CK2alpha, SMGs, TJs
50  2017 Disease-Modifying Effects of M1 Muscarinic Acetylcholine Receptor Activation in an Alzheimer's Disease Mouse Model. AD, MWM
51  2017 EEG machine learning for accurate detection of cholinergic intervention and Alzheimer's disease. AD, EEG
52  2017 Effects of cevimeline on excitability of parasympathetic preganglionic neurons in the superior salivatory nucleus of rats. BBB, SSN
53  2017 Effects of Chlorpyrifos or Methyl Parathion on Regional Cholinesterase Activity and Muscarinic Receptor Subtype Binding in Juvenile Rat Brain. ChE, CPF, OP, PND1
54  2017 Existence of muscarinic acetylcholine receptor (mAChR) and fibroblast growth factor receptor (FGFR) heteroreceptor complexes and their enhancement of neurite outgrowth in neural hippocampal cultures. FGF-2, FGFR, FGFRs, GPCRs, M1R, pFGFR, PLA
55  2017 Expression of muscarinic acetylcholine receptors in hepatocytes from rat fibrotic liver. ALB, Hyp
56  2017 Functional activation of Galphaq coupled to 5-HT2A receptor and M1 muscarinic acetylcholine receptor in postmortem human cortical membranes. 5-HT, G proteins
57  2017 Hijiki and sodium arsenite stimulate growth of human colorectal adenocarcinoma cells through ERK1/2 activation. EGFR
58  2017 l-Ornithine and l-lysine stimulate gastrointestinal motility via transient receptor potential vanilloid 1. Arg, GI, Lys, NO, Orn, TRPV1
59  2017 L-Satropane Prevents Retinal Neuron Damage by Attenuating Cell Apoptosis and Abeta Production via Activation of M1 Muscarinic Acetylcholine Receptor. GCL, I/R, INL, IPL, PRN
60  2017 Molecular mechanism for muscarinic M1 receptor-mediated endocytosis of TWIK-related acid-sensitive K+ 1 channels in rat adrenal medullary cells. AM, IR, PKC, PLC, TASK
61  2017 Muscarinic acetylcholine receptor but not nicotinic acetylcholine receptor plays a role in morphine-induced behavioral sensitization in rats. nAChR
62  2017 Muscarinic acetylcholine receptor-mediated tight junction opening is involved in epiphora in late phase of submandibular gland transplantation. SMG, TJ
63  2017 Muscarinic Acetylcholine Receptors and M-Currents Underlie Efferent-Mediated Slow Excitation in Calyx-Bearing Vestibular Afferents. ACh, CD, EVS, nAChRs
64  2017 Muscarinic receptor mediated signaling pathways in hepatocytes from CCL4 - induced liver fibrotic rat. ALB, FHC, Hyp, PI
65  2017 Novel muscarinic acetylcholine receptor hybrid ligands embedding quinuclidine and 1,4-dioxane fragments. ---
66  2017 Presynaptic Membrane Receptors Modulate ACh Release, Axonal Competition and Synapse Elimination during Neuromuscular Junction Development. AR, NMJ
67  2017 Sodium tanshinone IIA sulfonate stimulated Cl- secretion in mouse trachea. CF, COPD, STS
68  2017 Subunit profiling and functional characteristics of acetylcholine receptors in GT1-7 cells. AChRs, nAChR
69  2017 The antidepressant-like effects of biperiden may involve BDNF/TrkB signaling-mediated BICC1 expression in the hippocampus and prefrontal cortex of mice. BDNF, BICC1, CUS, TrkB
70  2017 Tonic inhibition of brown adipose tissue sympathetic nerve activity via muscarinic acetylcholine receptors in the rostral raphe pallidus. BAT, NEOS, rRPa, RVLM, SCOP, SNA
71  2016 A new family of insect muscarinic acetylcholine receptors. ---
72  2016 Accelerated structure-based design of chemically diverse allosteric modulators of a muscarinic G protein-coupled receptor. aMD, IFD, NAMs, NCI
73  2016 Acetylcholinesterase Inhibitors for Alzheimer's Disease Treatment Ameliorate Acetaminophen-Induced Liver Injury in Mice via Central Cholinergic System Regulation. AChEI, alpha7nAChR, ATR, JNK2, MLA
74  2016 Characterization of a Novel M1 Muscarinic Acetylcholine Receptor Positive Allosteric Modulator Radioligand, [3H]PT-1284. ACh, FLIPR, PAM
75  2016 Comparative analysis of pharmacological properties of xanomeline and N-desmethylclozapine in rat brain membranes. ---
76  2016 Developmental nicotine exposure alters cholinergic control of respiratory frequency in neonatal rats. ACh, nAChR
77  2016 Gallotannin-Enriched Extract Isolated from Galla Rhois May Be a Functional Candidate with Laxative Effects for Treatment of Loperamide-Induced Constipation of SD Rats. GEGR, Lop, SD
78  2016 Involvement of Striatal Cholinergic Interneurons and M1 and M4 Muscarinic Receptors in Motor Symptoms of Parkinson's Disease. ChIs, MSNs
79  2016 mAChR-dependent decrease in proteasome activity in the gustatory cortex is necessary for novel taste learning. CTA, GC, NMDAR, p70S6K
80  2016 Molecular Mechanisms of Action of M5 Muscarinic Acetylcholine Receptor Allosteric Modulators. ACh, IP, PAM
81  2016 Muscarinic acetylcholine receptors act in synergy to facilitate learning and memory. DH, RSC
82  2016 Novel Fused Arylpyrimidinone Based Allosteric Modulators of the M1 Muscarinic Acetylcholine Receptor. ACh, PAM
83  2016 Optogenetic activation of striatal cholinergic interneurons regulates L-dopa-induced dyskinesias. ChAT-Cre, LIDs, nAChR
84  2016 Positive Allosteric Modulation of the Muscarinic M1 Receptor Improves Efficacy of Antipsychotics in Mouse Glutamatergic Deficit Models of Behavior. ---
85  2016 Potentiation of M1 Muscarinic Receptor Reverses Plasticity Deficits and Negative and Cognitive Symptoms in a Schizophrenia Mouse Model. LTD, PAM, PFC
86  2016 Prefrontal Cortex-Mediated Impairments in a Genetic Model of NMDA Receptor Hypofunction Are Reversed by the Novel M1 PAM VU6004256. KD, LTD, NMDAR, PAMs, PFC
87  2016 Role of Nicotinic and Muscarinic Receptors on Synaptic Plasticity and Neurological Diseases. ACh, nAChR
88  2016 State-dependent alterations in sleep/wake architecture elicited by the M4 PAM VU0467154 - Relation to antipsychotic-like drug effects. APDs, NMDAR, NREM, PAM, REM
89  2016 The importance of muscarinic receptors in domestic animal diseases and therapy: Current and future perspectives. GI, mAChRs
90  2016 [Development of Researches on Mechanisms of Acupuncture Intervention in Improving Myocar-dial Ischemia by Balancing Interaction between beta-adrenergic Receptor and Acetylcholinergic Receptor Signal Transduction Pathway of Myocardiocytes]. beta-AR, MI
91  2015 Activation of muscarinic receptors in rat parotid acinar cells induces AQP5 trafficking to nuclei and apical plasma membrane. APM, AQP5, LPM
92  2015 Effect of Repeated Electroacupuncture Intervention on Hippocampal ERK and p38MAPK Signaling in Neuropathic Pain Rats. CCI, EA, EAS, ERK
93  2015 Endocannabinoids Mediate Muscarinic Acetylcholine Receptor-Dependent Long-Term Depression in the Adult Medial Prefrontal Cortex. 2-AG, eCB, LTD, MAGL, PFC
94  2015 Impact of acetylcholine and nicotine on human osteoclastogenesis in vitro. ChAT, nAChR, NNCS, PBMCs, TrkB
95  2015 Muscarinic acetylcholine receptor in cerebellar cortex participates in acetylcholine-mediated blood depressor response in rats. BP, MAP, MDMAP
96  2015 Muscarinic excitation of parvalbumin-positive interneurons contributes to the severity of pilocarpine-induced seizures. AP, DB, GABA, KO, PISs, PV, WT
97  2015 Rapid antidepressant actions of scopolamine: Role of medial prefrontal cortex and M1-subtype muscarinic acetylcholine receptors. IL, mPFC, mTORC1, PrL
98  2015 Role for the M1 Muscarinic Acetylcholine Receptor in Top-Down Cognitive Processing Using a Touchscreen Visual Discrimination Task in Mice. ---
99  2015 Role of the nicotinic acetylcholine receptor in Alzheimer's disease pathology and treatment. ACh, AD, nAChR
100  2015 Striatal dopamine release regulation by the cholinergic properties of the smokeless tobacco, gutkha. DA, nAChR