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■ Abbreviation / Long Form : mTORC / mammalian target of rapamycin complex

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Total Number of Papers: 48
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Abbreviation:   mTORC  (>> Co-occurring Abbreviation)
Long Form:   mammalian target of rapamycin complex
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No. Year Title Co-occurring Abbreviation
2022 AKT Signaling Downstream of KGF Is Necessary and Sufficient for Blocking Cyclophosphamide Bladder Injury. BAD, KGF
2022 AMPK's double-faced role in advanced stages of prostate cancer. AMPK, CSCs, EMT, GLUT, HIF1, PCa, PDHC
2022 Intracellular metabolic adaptation of intraepithelial CD4+CD8alphaalpha+ T lymphocytes. IELs, pS6
2022 Protective Effects of One 2,4-Dihydro-3H-Pyrazol-3-one Derivative against Posterior Capsular Opacification by Regulation of TGF-beta2/SMADs and Non-SMAD Signaling, Collagen I, and Fibronectin Proteins. DHPO, ERK, Fn, JUN, JUN, LDH, LEC, PCO, PI3K, SMAD, TGF-beta2
2022 [Seeking an Important Role on Metabolomics-Effects of beta-Estradiol on Lipoprotein Metabolism in Mammary Tumors]. ERK, LPL, MAPK, PI3K, siRNA
2021 A Mammalian Target of Rapamycin-Perilipin 3 (mTORC1-Plin3) Pathway is essential to Activate Lipophagy and Protects Against Hepatosteatosis. LDs, PLIN
2021 A novel role of CRTC2 in promoting nonalcoholic fatty liver disease. CRTC, Crtc2 LKO, HFD, NAFLD, SIRT, TG, TSC
2021 Dose-dependent beneficial effects of citrulline supplementation in short bowel syndrome in rats. EN, FSR
2021 T cell asymmetry and metabolic crosstalk can fine-tune immunological synapses. IS
10  2020 beta-Estradiol Enhanced Secretion of Lipoprotein Lipase from Mouse Mammary Tumor FM3A Cells. ERK, LPL, MAPK, PI3K, siRNA
11  2020 Cholesterol Handling in Lysosomes and Beyond. LAMP, LIMP, NPC
12  2019 Insulin promotes sodium transport but suppresses gluconeogenesis via distinct cellular pathways inhuman and rat renal proximal tubules. IRS-1, NBCe1
13  2018 Combining the mammalian target of rapamycin inhibitor, rapamycin, with resveratrol has a synergistic effect in multiple myeloma. MM
14  2018 Dihydrocelastrol exerts potent antitumor activity in mantle cell lymphoma cells via dual inhibition of mTORC1 and mTORC2. DHCE, MCL
15  2018 High-intensity eccentric training ameliorates muscle wasting in colon 26 tumor-bearing mice. CNT, ECC, ES, FOXO1, MuRF1, REDD
16  2018 Rapamycin and ZSTK474 can have differential effects at different post‑infection time‑points regarding CVB3 replication and CVB3‑induced autophagy. CVB3, p.i, PI3K
17  2018 Response gene to complement 32 suppresses adipose tissue thermogenic genes through inhibiting beta3-adrenergic receptor/mTORC1 signaling. BAT, beta3-AR, RGC, SVF, WAT
18  2017 MicroRNA-185-5p restores glucocorticoid sensitivity by suppressing the mammalian target of rapamycin complex (mTORC) signaling pathway to enhance glucocorticoid receptor autoregulation. ALL, GC, GR, miR-185-5p, mTORC2
19  2017 Novel enriched pathways in superficial malignant peripheral nerve sheath tumours and spindle/desmoplastic melanomas. MPNST, NF-kappaB, SDM
20  2017 Synergistic effect of copper and arsenic upon oxidative stress, inflammation and autophagy alterations in brain tissues of Gallus gallus. ATG5, CAT, COX-2, GPx, LC3, MDA, NF-kappaB, PI3K, PTGES, SOD, T-AOC, TNF-alpha
21  2017 Vascular Manifestations in Antiphospholipid Syndrome (APS): Is APS a Thrombophilia or a Vasculopathy? aPL, APS
22  2016 Molecular pathways of chronic kidney disease progression. EGFR
23  2015 CCR5-Dependent Activation of mTORC1 Regulates Translation of Inducible NO Synthase and COX-2 during Encephalomyocarditis Virus Infection. COX, EMCV, iNOS
24  2015 Leukemia inhibitory factor increases glucose uptake in mouse skeletal muscle. CNTF, LIF
25  2015 Morphoproteomics identifies constitutive activation of the mTORC2/Akt and NF-kappaB pathways and expressions of IGF-1R, Sirt1, COX-2, and FASN in peripheral T-cell lymphomas: pathogenetic implications and therapeutic options. COX, FASN, IGF-1R, NF, PTCL, SIRT1
26  2015 Mouse hippocampal phosphorylation footprint induced by generalized seizures: Focus on ERK, mTORC1 and Akt/GSK-3 pathways. ERK, MES
27  2015 Platelet-derived growth factor regulates vascular smooth muscle phenotype via mammalian target of rapamycin complex 1. Ang II, ERK, PDGF, PI3K, VSMCs
28  2014 Inhibition of the mTORC pathway in the antiphospholipid syndrome. PI3K
29  2014 Mammalian target of rapamycin complex 2 modulates alphabetaTCR processing and surface expression during thymocyte development. ---
30  2014 Phenylalanine sensitive K562-D cells for the analysis of the biochemical impact of excess amino acid. PKU
31  2013 A new functional role for mechanistic/mammalian target of rapamycin complex 1 (mTORC1) in the circadian regulation of L-type voltage-gated calcium channels in avian cone photoreceptors. L-VGCCs, mTORC1, PI3K-AKT
32  2013 Activation of AMPK/TSC2/PLD by alcohol regulates mTORC1 and mTORC2 assembly in C2C12 myocytes. AMPK, EtOH, PA, PI3K, PLD, TSC
33  2013 Control of the translational machinery by amino acids. GCN2, mRNAs
34  2013 TGF-beta/Smad3 activates mammalian target of rapamycin complex-1 to promote collagen production by increasing HIF-1alpha expression. HIF, HRE, sh, TGF
35  2013 Tsc1-Tp53 loss induces mesothelioma in mice, and evidence for this mechanism in human mesothelioma. ---
36  2013 [Function of mTORC2 and its roles in hematological malignancies]. ---
37  2012 Cystogenesis and elongated primary cilia in Tsc1-deficient distal convoluted tubules. cKO, DCT, TSC
38  2012 Regulatory effects of mTORC2 complexes in type I IFN signaling and in the generation of IFN responses. ISGs
39  2012 Safety, tolerability, pharmacokinetics and pharmacodynamics of AZD8055 in advanced solid tumours and lymphoma. ---
40  2012 Tumor suppressor TSC1 is critical for T-cell anergy. CD, ICOS, TSC
41  2011 Aging impairs contraction-induced human skeletal muscle mTORC1 signaling and protein synthesis. 4E-BP, ERK, MPS, mTOR, RE, S6K
42  2011 Exercise, amino acids, and aging in the control of human muscle protein synthesis. BFR, EAA, MPS
43  2011 mTORC2 protein complex-mediated Akt (Protein Kinase B) Serine 473 Phosphorylation is not required for Akt1 activity in human platelets [corrected]. ---
44  2011 Selective activation of Akt1 by mammalian target of rapamycin complex 2 regulates cancer cell migration, invasion, and metastasis. IGF-1, mTORC1, mTORC2, P-Rex1, PI3K
45  2010 Persistent hyperinsulinemic hypoglycemia of infancy: constitutive activation of the mTOR pathway with associated exocrine-islet transdifferentiation and therapeutic implications. PHHI, TEM
46  2010 The mechanical stress-activated serum-, glucocorticoid-regulated kinase 1 contributes to neointima formation in vein grafts. IGF, SMCs
47  2008 Novel role of the CXC chemokine receptor 3 in inflammatory response to arterial injury: involvement of mTORC1. IP-10, MIG
48  2008 The tuberous sclerosis complex regulates trafficking of glucose transporters and glucose uptake. FDG, GLUT, TSC