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■ Abbreviation / Long Form : shRNAs / short hairpin RNAs

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Total Number of Papers: 495
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Abbreviation:   shRNAs  (>> Co-occurring Abbreviation)
Long Form:   short hairpin RNAs
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No. Year Title Co-occurring Abbreviation
2020 Aurora B induces epithelial-mesenchymal transition by stabilizing Snail1 to promote basal-like breast cancer metastasis. BLBC, EMT
2020 CD2 is a surface marker for mouse and rat spermatogonial stem cells. SSC
2020 CDK12 inhibition mediates DNA damage and is synergistic with sorafenib treatment in hepatocellular carcinoma. CDK12, HCC
2020 Depletion of Vasohibin 1 Speeds Contraction and Relaxation in Failing Human Cardiomyocytes. HF, SVBP
2020 Deubiquitinase inhibitor degrasyn suppresses metastasis by targeting USP5-WT1-E-cadherin signalling pathway in pancreatic ductal adenocarcinoma. PDAC, WT1
2020 Effects of lentivirus-mediated CCR3 RNA interference on the function of mast cells of allergic rhinitis in mice. AR, CCR3, OVA, PGD2, shRNA
2020 Endogenous MicroRNA Competition as a Mechanism of shRNA-Induced Cardiotoxicity. miRNAs, rAAVs
2020 Epididymal protein 3A is upregulated and promotes cell proliferation in non-small cell lung cancer. EDDM3A, NSCLC
2020 Galectin-3 and TRIM16 coregulate osteogenic differentiation of human bone marrow-derived mesenchymal stem cells at least partly via enhancing autophagy. ALP, Co-IP, hBMSCs, qPCR, TRIM16, ULK1
10  2020 Gene knockdown via electroporation of short hairpin RNAs in embryos of the marine hydroid Hydractinia symbiolongicarpus. ---
11  2020 Inhibiting the Progression of Human Retinoblastoma Cell by Downregulation of MMP-2/MMP-9 Using Short Hairpin RNAs (shRNAs) In Vitro. MMPs, Rb, shRNA
12  2020 Knockdown of Chimeric RNA by RNAi. RNAi, siRNAs
13  2020 LINK-A lncRNA is upregulated in osteosarcoma and regulates migration, invasion and stemness of osteosarcoma cells. LINK-A, lncRNA, TGF-beta1
14  2020 Long non‑coding RNA CCAT1 enhances human non‑small cell lung cancer growth through downregulation of microRNA‑218. lncRNAs, NSCLC
15  2020 Long non‑coding RNA SNHG12 regulates cell proliferation, invasion and migration in endometrial cancer by targeting miR‑4429. EC, miR, MMP, NC, OV, SNHG12
16  2020 Mitoxantrone triggers immunogenic prostate cancer cell death via p53-dependent PERK expression. CALR, ChIP, DAMPs, eIF2alpha, HMGB1, ICD, MTX
17  2020 Pleiotropin enhances the osteo/dentinogenic differentiation potential of dental pulp stem cells. CCK-8, DPSCs, PTN
18  2020 PRMT5 silencing selectively affects MTAP-deleted mesothelioma: In vitro evidence of a novel promising approach. CDKN2A, MM, MTA, MTAP, PRMT5
19  2020 Reactivation of Epstein-Barr Virus by HIF-1alpha Requires p53. ChIP, EBV's, HIF-1alpha, HRE
20  2020 Runx2 silencing promotes adipogenesis via down-regulation of DLK1 in chondrogenic differentiating MSCs. MSCs
21  2020 SATB1 promotion of trophoblast stem cell renewal through regulation of threonine dehydrogenase. SATB1, TDH, TS
22  2020 Suppression of TGF-beta and IL-10 receptors on self-differentiated dendritic cells by short-hairpin RNAs enhanced activation of effector T-cells against cholangiocarcinoma cells. CCA, DC, IL-10, SD-DCs, TGF-beta
23  2020 The lncRNA SNHG3 accelerates papillary thyroid carcinoma progression via the miR-214-3p/PSMD10 axis. ceRNA, lncRNA, miRNAs, PTC, RIP, SNHG3
24  2020 Using a Lentivirus-Based Inducible RNAi Vector to Silence a Gene. RNAi, TOP
25  2020 [Knockdown of YTH N6-methyladenosine RNA binding protein 2 (YTHDF2) inhibits cell proliferation and promotes apoptosis in cervical cancer cells]. ---
26  2019 Boosting AgoshRNA activity by optimized 5'-terminal nucleotide selection. Ago2, nt, pol, RNAi, siRNAs
27  2019 Changes in the transcriptome profile of breast cancer cells grown as spheroids. ---
28  2019 Co-Delivery of RUNX2-Targeting miRNAs and shRNAs Using Nanoparticles Composed of Dexamethasone and PEI Induces Chondrogenesis of Human Mesenchymal Stem Cells. hMSCs, miRNAs, RNAi
29  2019 DNA damage-induced activation of ATM promotes beta-TRCP-mediated ARID1A ubiquitination and destruction in gastric cancer cells. ARID1A, ATM, Co-IP, KD
30  2019 Efficient Knockdown and Lack of Passenger Strand Activity by Dicer-Independent shRNAs Expressed from Pol II-Driven MicroRNA Scaffolds. Pol III, pri-miRNA
31  2019 Enhancement of gene knockdown efficiency by CNNC motifs in the intronic shRNA precursor. RNAi
32  2019 Enzymatic construction of shRNA library from oligonucleotide library. RNAi
33  2019 Exosome-transmitted LINC00461 promotes multiple myeloma cell proliferation and suppresses apoptosis by modulating microRNA/BCL-2 expression. lncRNAs, miR, MM, MSC, PCR
34  2019 Fak silencing impairs osteogenic differentiation of bone mesenchymal stem cells induced by uniaxial mechanical stretch. ALP, BMSCs, DO, FAK, ILK
35  2019 Functional RNAi Screens Define Distinct Protein Kinase Vulnerabilities in EGFR-Dependent HNSCC Cell Lines. EGFR, ErbB, ERK, HNSCC, MEK, MTOR
36  2019 Increased BMPR1A Expression Enhances the Adipogenic Differentiation of Mesenchymal Stem Cells in Patients with Ankylosing Spondylitis. AS, AS, BMPR1A, HE, MSCs, ORO
37  2019 Influence of a 3' Terminal Ribozyme on AgoshRNA Biogenesis and Activity. Ago2, HDV, RNAi
38  2019 Loss of thymidine kinase 1 inhibits lung cancer growth and metastatic attributes by reducing GDF15 expression. GDF15, LUAD, TK1
39  2019 Promoter cross-talk affects the inducible expression of intronic shRNAs from the tetracycline response element. CMV, RNAi, rtTA3, siRNAs, TRE
40  2019 Sac1 Phosphoinositide Phosphatase Regulates Foam Cell Formation by Modulating SR-A Expression in Macrophages. LDL, SR-A
41  2019 Significant inhibition of re-emerged and emerging swine enteric coronavirus in vitro using the multiple shRNA expression vector. PDCoV, PEDV, RNAi, SADS-CoV, SECoVs
42  2019 The lncRNA HOXA11-AS promotes glioma cell growth and metastasis by targeting miR-130a-5p/HMGB2. HMGB2, HOXA11-AS, IHC, lncRNAs, qRT-PCR
43  2019 The serum biomarker chemerin promotes tumorigenesis and metastasis in oral squamous cell carcinoma. ChemR23, OSCC, R-chemerin, RARRES2, siRNA
44  2019 TRIM52 promotes colorectal cancer cell proliferation through the STAT3 signaling. CCK-8, CRC, TRIM
45  2019 Valproic acid exhibits anti-tumor activity selectively against EGFR/ErbB2/ErbB3-coexpressing pancreatic cancer via induction of ErbB family members-targeting microRNAs. ---
46  2019 Weighted Gene Coexpression Network Analysis Identifies Cysteine-Rich Intestinal Protein 1 (CRIP1) as a Prognostic Gene Associated with Relapse in Patients with Acute Myeloid Leukemia. AML, CCK-8, CRIP1, WGCNA
47  2019 [Musashi-1 positively regulates growth and proliferation of hepatoma cells in vitro]. HCC, Msi1
48  2018 A Direct Interaction Between P53-Binding Protein 1 and Minichromosome Maintenance Complex in Hepg2 Cells. GST, HA, HCC, IP, MCMs, MS
49  2018 Activated CXCL5-CXCR2 axis promotes the migration, invasion and EMT of papillary thyroid carcinoma cells via modulation of beta-catenin pathway. CXCL, CXCR2, E-cadherin, EMT, PTC, rhCXCL5
50  2018 Administration of chitosan-tripolyphosphate-DNA nanoparticles to knockdown glutamate dehydrogenase expression impairs transdeamination and gluconeogenesis in the liver. GDH, TPP
51  2018 Anti-Mullerian hormone is a survival factor and promotes the growth of rhesus macaque preantral follicles during matrix-free culture. AMH
52  2018 Conditional Manipulation of Gene Function in Human Cells with Optimized Inducible shRNA. hPSCs, OPTiKD
53  2018 Kallikrein-related peptidase 7 is a potential target for the treatment of pancreatic cancer. KLKs, RTCA
54  2018 Knockdown of ribosomal protein S15A inhibits proliferation of breast cancer cells through induction of apoptosis in vitro. RPS15A
55  2018 Lentiviral-mediated BCL2 gene knockdown using comparative microRNA adaptive shRNAs. Bcl-2, HEK293T, LV, PCR, RNAi
56  2018 Long noncoding RNA HOTAIR promotes the self-renewal of leukemia stem cells through epigenetic silencing of p15. AML, EZH2, HSPCs, LSC
57  2018 Modeling Anti-HIV-1 HSPC-Based Gene Therapy in Humanized Mice Previously Infected with HIV-1. HSPC, LTR
58  2018 Pooled shRNA Screen for Reactivation of MeCP2 on the Inactive X Chromosome. CRISPR, MeCP2, XCI, Xi
59  2018 Silencing of H19 inhibits the adipogenesis and inflammation response in ox-LDL-treated Raw264.7 cells by up-regulating miR-130b. AS, CADs, HDL-C, LDL-C, LncRNA, oxLDL, TC
60  2018 Sirtuin 2 Isoform 1 Enhances Hepatitis B Virus RNA Transcription and DNA Synthesis through the AKT/GSK-3beta/beta-Catenin Signaling Pathway. GSK-3beta, HCCs, SIRT2
61  2018 The c-Jun and JunB transcription factors facilitate the transit of classical Hodgkin lymphoma tumour cells through G1. AP-1, cHL
62  2017 A novel animal model for neuroinflammation and white matter degeneration. MS, scAAV8
63  2017 An optimized lentiviral vector system for conditional RNAi and efficient cloning of microRNA embedded short hairpin RNA libraries. RNAi
64  2017 Colonic PDGFRalpha Overexpression Accompanied Forkhead Transcription Factor FOXO3 Up-Regulation in STZ-Induced Diabetic Mice. P-FOXO3, shRNA, STZ
65  2017 CRL4BDCAF11 E3 ligase targets p21 for degradation to control cell cycle progression in human osteosarcoma cells. CDKs, CKIs, CRL4B, CUL4B, DDB1, RBX1
66  2017 Downregulation of calbindin 1, a calcium-binding protein, reduces the proliferation of osteosarcoma cells. CALB1
67  2017 Evaluation of RNAi and CRISPR technologies by large-scale gene expression profiling in the Connectivity Map. CGS, CMap, CRISPR, miRNA, RNAi, sgRNAs
68  2017 Expression of short hairpin RNAs using the compact architecture of retroviral microRNA genes. bp, cshRNA, miRNA, RISC, RNAPIII, siRNAs
69  2017 Functional characterization of Pol III U6 promoters for gene knockdown and knockout in Plutella xylostella. Pol-III, PSEA, sgRNAs, snRNA
70  2017 Genetic Manipulation of the Avian Urogenital System Using In Ovo Electroporation. ---
71  2017 Human Cytomegalovirus MicroRNAs miR-US5-1 and miR-UL112-3p Block Proinflammatory Cytokine Production in Response to NF-kappaB-Activating Factors through Direct Downregulation of IKKalpha and IKKbeta. HCMV, IKK, IL-1beta, miRNAs, TNF-alpha, UTRs
72  2017 Identification of Chloride Intracellular Channel Protein 3 as a Novel Gene Affecting Human Bone Formation. ALP, CLIC3, hMSCs, LS/MS, MSCs, NEK9, PTDSS1
73  2017 In vivo inhibition of influenza A virus replication by RNA interference targeting the PB2 subunit via intratracheal delivery. PA, siRNA
74  2017 Influence of the loop size and nucleotide composition on AgoshRNA biogenesis and activity. Ago2, RNAi, siRNAs
75  2017 Intron-specific shRNA-mediated downregulation of survivin and promotion of apoptosis in HeLa cells. FCM
76  2017 Luciferase shRNA Presents off-Target Effects on Voltage-Gated Ion Channels in Mouse Hippocampal Pyramidal Neurons. RNAi, shScrs
77  2017 Lure-and-Kill Yeast Interfering RNA Larvicides Targeting Neural Genes in the Human Disease Vector Mosquito Aedes aegypti. fez2, LRC
78  2017 Notch1 suppresses prostate cancer cell invasion via the metastasis-associated 1-KiSS-1 metastasis-suppressor pathway. Kiss1, MTA1, PCa
79  2017 Prediction of potent shRNAs with a sequential classification algorithm. ---
80  2017 RNAi-mediated human Nestin silence inhibits proliferation and migration of malignant melanoma cells by G1/S arrest via Akt-GSK3beta-Rb pathway. hNestin, RT-PCR
81  2017 Roles of lncRNA UCA1-miR-18a-SOX6 axis in preventing hypoxia injury following cerebral ischemia. lncRNA, PC, Sox6, SOX6, UCA1
82  2017 Serine hydroxymethyl transferase 1 stimulates pro-oncogenic cytokine expression through sialic acid to promote ovarian cancer tumor growth and progression. HGS, SHMT1, WT1
83  2017 shRNA-mediated silencing of hTERT suppresses proliferation and promotes apoptosis in osteosarcoma cells. hTERT
84  2017 SOX12: a novel potential target for acute myeloid leukaemia. AML, NOD/SCID, RT-PCR, SOX
85  2017 Targeting of RAGE-ligand signaling impairs breast cancer cell invasion and metastasis. MEK-EMT, RAGE
86  2017 The creatine kinase pathway is a metabolic vulnerability in EVI1-positive acute myeloid leukemia. AML
87  2017 Tumor-promoting effects of cannabinoid receptor type 1 in human melanoma cells. CB1
88  2017 WITHDRAWN: LncRNA-HOTAIR Activates Tumor Cell Proliferation and Migration by Suppressing MiR-326 in Cervical Cancer. KD
89  2017 Yeast interfering RNA larvicides targeting neural genes induce high rates of Anopheles larval mortality. lrc, otk, siRNA
90  2017 [Effect of clock gene PER1 knockdown on clock gene networks in human oral squamous cell carcinoma]. ---
91  2016 A novel multi-target RNAi adenovirus inhibits hepatoma cell proliferation, migration, and induction of angiogenesis. CCR1, EpCAM, HCC, VEGFR2
92  2016 Adenovirus-mediated shRNA interference against HSV-1 replication in vitro. AdV5, HSV-1, MOI
93  2016 BCR/ABL increases EZH2 levels which regulates XIAP expression via miRNA-219 in chronic myeloid leukemia cells. 3'-UTR, BMMNCs, CML
94  2016 Brahma-related gene 1 induces apoptosis in a p53-dependent manner in human rheumatoid fibroblast-like synoviocyte MH7A. BRG1, CASP3, FLS, IP, RA
95  2016 Design of shRNA and miRNA for Delivery to the CNS. CNS, miRNAs, RISC, RNAi
96  2016 Functional Analysis of Novel Candidate Regulators of Insulin Secretion in the MIN6 Mouse Pancreatic beta Cell Line. GSIS
97  2016 Inhibition of PID1/NYGGF4/PCLI1 gene expression highlights its role in the early events of the cell cycle in NIH3T3 fibroblasts. ---
98  2016 Inhibition of Respiratory Syncytial Virus Replication by Simultaneous Targeting of mRNA and Genomic RNA Using Dual-Targeting siRNAs. ---
99  2016 Introduction of shRNAs, miRNAs, or AntagomiRs into Primary Human Liver Cells Through Lentiviral Vectors. MOI, RNAi
100  2016 miR-494-3p Induces Cellular Senescence and Enhances Radiosensitivity in Human Oral Squamous Carcinoma Cells. BMI1, miRNAs, OSCC, RB1