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■ Abbreviation / Long Form : uPA / urokinase-type plasminogen activator

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Abbreviation:   uPA  (>> Co-occurring Abbreviation)
Long Form:   urokinase-type plasminogen activator
 Abbreviation Variation
 Long Form Variation
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No. Year Title Co-occurring Abbreviation
2019 Amentoflavone Induces Apoptosis and Reduces Expression of Anti-apoptotic and Metastasis-associated Proteins in Bladder Cancer. c-FLIP, MMP, VEGF
2019 Antithrombotic Effect of Oral Administration of Mozuku (Cladosiphon okamuranus, Brown Seaweed) Extract in Rat. ---
2019 Association of uPA and PAI-1 tumor levels and 4G/5G variants of PAI-1 gene with disease outcome in luminal HER2-negative node-negative breast cancer patients treated with adjuvant endocrine therapy. DFS, EFS, OS, PAI-1
2019 Bismaleimide cross-linked anthrax toxin forms functional octamers with high specificity in tumor targeting. CLPA, MMP, PA
2019 Changes in uPA, PAI-1, and TGF-beta Production during Breast Cancer Cell Interaction with Human Mesenchymal Stroma/Stem-Like Cells (MSC). MSC, PAI-1
2019 Characterising the Subsite Specificity of Urokinase-Type Plasminogen Activator and Tissue-Type Plasminogen Activator using a Sequence-Defined Peptide Aldehyde Library. tPA
2019 Characterizing the role of tissue-type plasminogen activator in a mouse model of Group A streptococcal infection. tPA
2019 Circulating uPA as a potential prognostic biomarker for resectable esophageal squamous cell carcinoma. CK19, CK20, ESCC, MMP9, qRT-PCR
2019 Coordinated expression of vascular endothelial growth factor A and urokinase-type plasminogen activator contributes to classical swine fever virus Shimen infection in macrophages. CSF, VEGF-A
10  2019 Correlation of the invasive potential of glioblastoma and expression of caveola-forming proteins caveolin-1 and CAVIN1. CAVIN1, GBM, MMP-2
11  2019 Deficiency of Plasminogen Activator Inhibitor Type 2 Limits Brain Edema Formation after Traumatic Brain Injury. PAI-1, TBI, WT
12  2019 Deficiency of urokinase-type plasminogen activator and its receptor affects social behavior and increases seizure susceptibility. PTZ
13  2019 ERK1/2 mediates the lipopolysaccharide-induced upregulation of FGF-2, uPA, MMP-2, MMP-9 and cellular migration in cardiac fibroblasts. FGF, MMPs, tPA
14  2019 Expression of urokinase plasminogen activator (uPA) in the leukocytes and tissues of patients with benign and malignant breast lesions. BC, RT-PCR
15  2019 Fibrin and Fibrinolysis in Cancer. ECM, PAI-1, uPAR
16  2019 Graphene nanosheets as an electric mediator for ultrafast sensing of urokinase plasminogen activator receptor-A biomarker of cancer. Ab, AFM, CV, EDC, FTIR, FTO, GNs, NHS, SEM, uPAR
17  2019 Increased urokinase and consumption of alpha2 -antiplasmin as an explanation for the loss of benefit of tranexamic acid after treatment delay. APTT, tPA, TXA
18  2019 Influence of miR-34a on preeclampsia through the Notch signaling pathway. Hes-1, ICN, miR-34a, RT-PCR
19  2019 Inherited disorders of the fibrinolytic pathway. alpha2-AP, PAI-1, QPD
20  2019 Inhibiting the urokinase-type plasminogen activator receptor system recovers STZ-induced diabetic nephropathy. FPRs, STZ
21  2019 Inhibition by Epigallocatechin Gallate of IL-1-Induced Urokinase-Type Plasminogen Activator Expression and Collagen Degradation by Corneal Fibroblasts. EGCG, IL, MMP1
22  2019 Insulin Treatment Forces Arteriogenesis in Diabetes Mellitus by Upregulation of the Early Growth Response-1 (Egr-1) Pathway in Mice. DM, Egr-1, ICAM-1, SF-1
23  2019 Investigations on the Role of the Fibrinolytic Pathway on Outflow Facility Regulation. KO, PLAT, PLG, TA, tPA, WT
24  2019 Knockdown of Notch1 inhibits nasopharyngeal carcinoma cell growth and metastasis via downregulation of CCL2, CXCL16, and uPA. NPC, shRNA
25  2019 Multiscale modelling of cancer response to oncolytic viral therapy. ECM, OV
26  2019 Near-Infrared Light Activated Thermosensitive Ion Channel to Remotely Control Transgene System for Thrombolysis Therapy. NIR, PTS
27  2019 Novel urokinase-plasminogen activator inhibitor SPINK13 inhibits growth and metastasis of hepatocellular carcinoma in vivo. HCC, MMPs
28  2019 PAI-1 but Not PAI-2 Gene Deficiency Attenuates Ischemic Brain Injury After Experimental Stroke. MCAO, PAI-1, PAS, tPA
29  2019 Peptide P7 inhibits the bFGF-stimulated proliferation and invasion of SKOV3 cells. bFGF, MMP
30  2019 PH sensitive shell-core platform block DNA repair pathway to amplify irreversible DNA damage of triple negative breast cancer. NPs, siRNA, TNBC, uPAR
31  2019 Plasminogen activator inhibitor 2 (PAI2) inhibits invasive potential of hepatocellular carcinoma cells in vitro via uPA- and RB/E2F1-related mechanisms. HCC, PAI-2
32  2019 Probable Roles of Coagulation Cascade and Fibrinolysis System in the Development of Allergic Rhinitis. AR, PAI-1
33  2019 Prognostic role of the urokinase plasminogen activator (uPA) system in patients with nonmuscle invasive bladder cancer. HR, NMIBC, PFS, RFS, TURB, uPAR
34  2019 Rapid identification of urokinase plasminogen activator inhibitors from Traditional Chinese Medicines based on ultrafiltration, LC-MS and in silico docking. TCMs
35  2019 Sentinel Lymph Node-Targeted Therapy by Oncolytic Sendai Virus Suppresses Micrometastasis of Head and Neck Squamous Cell Carcinoma in an Orthotopic Nude Mouse Model. cN0, HNSCC, LNM, SLN
36  2019 SerpinB2 inhibits migration and promotes a resolution phase signature in large peritoneal macrophages. GSEA, LPM
37  2019 Sodium retention by uPA in nephrotic syndrome? ---
38  2019 Specifically targeting cancer proliferation and metastasis processes: the development of matriptase inhibitors. HGF, MMPs, PAR-2, SARs
39  2019 Suppression of Tumor Growth and Metastases by Targeted Intervention in Urokinase Activity with Cyclic Peptides. ---
40  2019 TGF-beta-mediated regulation of plasminogen activators is human telomerase reverse transcriptase dependent in cancer cells. EMTs, hTERT, TGF-beta
41  2019 The importance of selected markers of inflammation and blood-brain barrier damage for short-term ischemic stroke prognosis. BDNF, CRP, IL-2, IL-6, mRS, NIHSS, NSE, PLT, TNF-alpha, VEGF, WBC
42  2019 The mechanical and pharmacological regulation of glioblastoma cell migration in 3D matrices. tPA
43  2019 The Plasminogen Activation System Promotes Neurorepair in the Ischemic Brain. CNS, PA, tPA, uPAR
44  2019 The prognostic relevance of urokinase-type plasminogen activator (uPA) in the blood of patients with metastatic breast cancer. BC, CTCs
45  2019 The Role of Fibrinolytic Regulators in Vascular Dysfunction of Systemic Sclerosis. alpha2-AP, EC, EndoMT, PAI-1, PLG, SSc, tPA
46  2019 The uPAR System as a Potential Therapeutic Target in the Diseased Eye. RP
47  2019 The Urokinase Plasminogen Activation System in Rheumatoid Arthritis: Pathophysiological Roles and Prospective Therapeutic Targets. PAS, RA, tPA
48  2019 The urokinase-type plasminogen activator system as drug target in retinitis pigmentosa: New pre-clinical evidence in the rd10 mouse model. PD, RP
49  2019 Thymoquinone inhibits metastasis of renal cell carcinoma cell 786-O-SI3 associating with downregulation of MMP-2 and u-PA and suppression of PI3K/Src signaling. MMP, TGF, TQ
50  2019 uPA affects the CRSsNP nasal mucosa epithelium apoptosis by regulating WIF1. CRS, CRSsNP, HNEC, WIF1
51  2019 Urokinase Plasminogen Activator: A Potential Thrombolytic Agent for Ischaemic Stroke. rt-PA
52  2019 Urokinase-type plasminogen activator (uPA) is not essential for epithelial sodium channel (ENaC)-mediated sodium retention in experimental nephrotic syndrome. ENaC, ENaC, PLG
53  2019 Urokinase-type plasminogen activator contributes to amiloride-sensitive sodium retention in nephrotic range glomerular proteinuria in mice. ---
54  2019 Zerumbone Suppresses Human Colorectal Cancer Invasion and Metastasis via Modulation of FAk/PI3k/NFkappaB-uPA Pathway. CRC, FAK, NF, PCR, ZER
55  2018 (-)-Epigallocatechin gallate derivatives reduce the expression of both urokinase plasminogen activator and plasminogen activator inhibitor-1 to inhibit migration, adhesion, and invasion of MDA-MB-231 cells. EGCG, ERK, MAPK, MMP, PAI-1, PI3K
56  2018 6-Substituted Hexamethylene Amiloride (HMA) Derivatives as Potent and Selective Inhibitors of the Human Urokinase Plasminogen Activator for Use in Cancer. ENaC, HMA
57  2018 A Fluorescent Carbon Nanotube Sensor Detects the Metastatic Prostate Cancer Biomarker uPA. BSA, SWCNT
58  2018 A label-free photoelectrochemical biosensor for urokinase-type plasminogen activator detection based on a g-C3N4/CdS nanocomposite. ---
59  2018 A One-Pot "Triple-C" Multicyclization Methodology for the Synthesis of Highly Constrained Isomerically Pure Tetracyclic Peptides. Aha, CEPS, FXIIa
60  2018 Acute hepatitis B virus infection in humanized chimeric mice has multiphasic viral kinetics. cccDNA, CI, cps, HBV, p.i, SCID
61  2018 Anti-Metastatic Effects of Antrodan with and without Cisplatin on Lewis Lung Carcinomas in a Mouse Xenograft Model. BUN, ERK2, ERKs, IFN-gamma, IL-6, JNKs, LLC, MAPKs, MMP-9, STAT3
62  2018 Anti-metastatic potential of a proton beam is regulated by p38 MAPK/c-Fos signaling pathway in TPA-treated HepG2 human hepatocellular carcinoma. MMP-9, uPAR, VEGF
63  2018 Antibody-Mediated Neutralization of uPA Proteolytic Function Reduces Disease Progression in Mouse Arthritis Models. CIA, uPAR
64  2018 AP1 mediates uPA/uPAR induced FUT4 expression and trophoblast invasion. AP-1, ChIP, EMSA, uPAR
65  2018 Association between uremic toxin-anthranilic acid and fibrinolytic system activity in predialysis patients at different stages of chronic kidney disease. AA, CKD, PAI-1, PAP, tPA
66  2018 Benzamide and Benzamidine Compounds as New Inhibitors of Urokinasetype Plasminogen Activators. 5-FU
67  2018 Bisdemethoxycurcumin Suppresses Migration and Invasion of Human Cervical Cancer HeLa Cells via Inhibition of NF-B, MMP-2 and -9 Pathways. BDMC, Grb2, MMP-2, NF-B
68  2018 Can components of the plasminogen activation system predict the outcome of kidney transplants? PAI-1, PAS, uPAR
69  2018 Characteristics of fibrinolytic disorders in acute promyelocytic leukemia. APL, ATO, PA, PAI-1, Pg, Pn, tPA, uPAR
70  2018 Cinnamomum Cassia Extracts Suppress Human Lung Cancer Cells Invasion by Reducing u-PA/MMP Expression through the FAK to ERK Pathways. CCE, ERK, FAK, MMP, Rho
71  2018 Cleavage of peptidic inhibitors by target protease is caused by peptide conformational transition. ---
72  2018 Computational Approaches and Analysis for a Spatio-Structural-Temporal Invasive Carcinoma Model. ---
73  2018 Defective TAFI activation in hemophilia A mice is a major contributor to joint bleeding. aHA, FVIII, TAFI, WT
74  2018 Delta-tocotrienol inhibits non-small-cell lung cancer cell invasion via the inhibition of NF-kappaB, uPA activator, and MMP-9. deltaT, MMP-9, NF-kappaB, NSCLC
75  2018 Design, Synthesis, and Testing of Potent, Selective Hepsin Inhibitors via Application of an Automated Closed-Loop Optimization Platform. HGF
76  2018 Discovery of selective urokinase plasminogen activator (uPA) inhibitors as a potential treatment for multiple sclerosis. ---
77  2018 Down regulation of u-PA by a nutrient mixture in hemangioma (EOMA) cells by inducing caspase-dependent apoptosis. ---
78  2018 Downregulation of SPINK13 Promotes Metastasis by Regulating uPA in Ovarian Cancer Cells. EMT, OC
79  2018 Effect of a synthetic inhibitor of urokinase plasminogen activator on the migration and invasion of human cervical cancer cells in vitro. ---
80  2018 Effects of TGF-beta1 on plasminogen activation in human dental pulp cells: Role of ALK5/Smad2, TAK1 and MEK/ERK signalling. ELISA, PA, PAI-1, suPAR, TGF-beta1, uPAR
81  2018 Estramustine Phosphate Inhibits TGF-beta-Induced Mouse Macrophage Migration and Urokinase-Type Plasminogen Activator Production. EP, MT, TGF-beta
82  2018 Evaluation of the Inhibitory Effects of Genipin on the Fluoxetine-Induced Invasive and Metastatic Model in Human HepG2 Cells. AP-1, FXT, GNP, HCC, MMPs, NF-kB, p-Akt, TIMPs
83  2018 Explaining urokinase type plasminogen activator inhibition by amino-5-hydroxybenzimidazole and two naphthamidine-based compounds through quantum biochemistry. DFT, MFCC
84  2018 Expression of urokinase-type plasminogen activator and its receptor in squamous cell carcinoma of the oral tongue. SCCOT
85  2018 High expression of uPA related to p38MAPK in esophageal cancer indicates poor prognosis. ---
86  2018 HPLC-MS/MS analysis of mesupron and its application to a pharmacokinetic study in rats. ---
87  2018 IL-1beta induced IL-8 and uPA expression/production of dental pulp cells: Role of TAK1 and MEK/ERK signaling. ERK, IL-1beta, MEK, RT-PCR, TAK1
88  2018 Inhibition of breast cancer metastasis by co-transfection of miR-31/193b-mimics. RhoA
89  2018 Invivo evaluation of urokinase-loaded hollow nanogels for sonothrombolysis on suture embolization-induced acute ischemic stroke rat model. i.v, MCA, US
90  2018 Involvement of RSK1 activation in malformin-enhanced cellular fibrinolytic activity. MA1
91  2018 IOP lowering effect of topical trans-resveratrol involves adenosine receptors and TGF-beta2 signaling pathways. AH, AR, HTMC, IOP, PLC, SIOH, tPA
92  2018 Lectin BS-I inhibits cell migration and invasion via AKT/GSK-3beta/beta-catenin pathway in hepatocellular carcinoma. BS-I, HCC, MMP2, MMP9
93  2018 Levels of uPA and PAI-1 in breast cancer and its correlation to Ki67-index and results of a 21-multigene-array. PAI-1, RS
94  2018 Ligand binding modulates the structural dynamics and activity of urokinase-type plasminogen activator: A possible mechanism of plasminogen activation. HDX-MS, muPA
95  2018 Lysophosphatidic acid increases invitro maturation efficiency via uPA-uPAR signaling pathway in cumulus cells. BL, CL, EGF, IVF, IVM, LPA, MAPK, PA, ROS, uPAR
96  2018 Meta-Analysis of Preclinical Studies of Fibrinolytic Therapy for Acute Lung Injury. ALI, BALF, PAI-1, tPA
97  2018 Micro-RNA profile and proteins in peritoneal fluid from women with endometriosis: their relationship with sterility. IL, MIP1beta, miRNA, MMP3, PAI-1, PF, RANTES, TIMP-1, TSP-1, VEGF-A
98  2018 MicroRNA-645 targets urokinase plasminogen activator and decreases the invasive growth of MDA-MB-231 triple-negative breast cancer cells. miR-645, MMPs, TNBC
99  2018 Multifaceted Role of the Urokinase-Type Plasminogen Activator (uPA) and Its Receptor (uPAR): Diagnostic, Prognostic, and Therapeutic Applications. PA
100  2018 Naringenin Attenuated Prostate Cancer Invasion via Reversal of Epithelial-to-Mesenchymal Transition and Inhibited uPA Activity. SNAI1, SNAI2, TWIST1