| 1 |
2021 |
11β-hydroxysteroid dehydrogenases: A growing multi-tasking family. |
11betaHSD1L, MetS, RORgamma |
| 2 |
2021 |
Endogenous Glucocorticoid Metabolism in Bone: Friend or Foe. |
GCs |
| 3 |
2021 |
Modulation of 11β-hydroxysteroid dehydrogenase functions by the cloud of endogenous metabolites in a local microenvironment: The glycyrrhetinic acid-like factor (GALF) hypothesis. |
GALF, GALFs, GR, MR |
| 4 |
2021 |
Steroid-converting enzymes in human adipose tissues and fat deposition with a focus on AKR1C enzymes. |
--- |
| 5 |
2020 |
Endogenous urinary glucocorticoid metabolites and mortality in prednisolone-treated renal transplant recipients. |
RTR, THE |
| 6 |
2020 |
Reciprocal Regulation of HSD11B1 and HSD11B2 Predicts Glucocorticoid Sensitivity in Childhood Acute Lymphoblastic Leukemia. |
ALL |
| 7 |
2020 |
Significance of glucocorticoid signaling in triple-negative breast cancer patients: a newly revealed interaction with androgen signaling. |
DEX, DHT, GCs, GR, AR, SGK1, TNBC |
| 8 |
2020 |
Synthesis of Novel 2-(Isopropylamino)thiazol-4(5H)-one Derivatives and Their Inhibitory Activity of 11beta-HSD1 and 11beta-HSD2 in Aspect of Carcinogenesis Prevention. |
--- |
| 9 |
2020 |
Two new sesquiterpenes from cultures of the fungus Irpex lacteus. |
--- |
| 10 |
2020 |
[Genetic expression differences of 11 beta-hydroxysteroid dehydrogenase in the bone microvascular endothelial cells derived from different regions of the human femoral head]. |
BMECs, RT-PCR |
| 11 |
2019 |
11alpha-Hydroxyprogesterone, a potent 11beta-hydroxysteroid dehydrogenase inhibitor, is metabolised by steroid-5alpha-reductase and cytochrome P450 17alpha-hydroxylase/17,20-lyase to produce C11alpha-derivatives of 21-deoxycortisol and 11-hydroxyandrostenedione in vitro. |
CYP17A1, SRD5A |
| 12 |
2019 |
11beta-Hydroxysteroid dehydrogenases control access of 7beta,27-dihydroxycholesterol to retinoid-related orphan receptor gamma. |
7-KC, 7beta-OHC, 7beta27OHC, 7k27OHC, RORgamma |
| 13 |
2019 |
A Review of the Pharmacological Efficacy and Safety of Licorice Root from Corroborative Clinical Trial Findings. |
--- |
| 14 |
2019 |
Application of ELISA Technique and Human Microsomes in the Search for 11beta-Hydroxysteroid Dehydrogenase Inhibitors. |
--- |
| 15 |
2019 |
Endocrine modulation of Brucella abortus-infected osteocytes function and osteoclastogenesis via modulation of RANKL/OPG. |
Cx43, GR |
| 16 |
2019 |
Phenotypic flexibility of glucocorticoid signaling in skeletal muscles of a songbird preparing to migrate. |
CORT, GR, MR |
| 17 |
2019 |
Physiological effects of 5alpha-dihydrotestosterone in male mummichog (Fundulus heteroclitus) are dose and time dependent. |
11-KT, 17beta-HSD, 3beta-HSD, CYP17A1, DHT, StAR |
| 18 |
2019 |
Role of gut metabolism of adrenal corticosteroids and hypertension: clues gut-cleansing antibiotics give us. |
--- |
| 19 |
2019 |
The 11beta-hydroxysteroid dehydrogenase isoforms: pivotal catalytic activities yield potent C11-oxy C19 steroids with 11betaHSD2 favouring 11-ketotestosterone, 11-ketoandrostenedione and 11-ketoprogesterone biosynthesis. |
--- |
| 20 |
2019 |
The impact of early-life stress on corticosteroid carrier protein levels and 11beta-hydroxysteroid dehydrogenase 1 expression in adolescent rats. |
CBG, ELS, MS |
| 21 |
2019 |
[Study on the relationship between 11beta-hydroxysteroid dehydrogenase and glucocorticoid response in nasal polyps]. |
CRSwNP, insensitive group, ROC, RT-PCR, sensitive group |
| 22 |
2018 |
11beta-hydroxysteroid dehydrogenases as targets in the treatment of steroid-associated femoral head necrosis using antler extract. |
ALP, ANFH, CT, SANFH |
| 23 |
2018 |
A new guaiane sesquiterpene from cultures of the fungus Fulvifomes kanehirae. |
--- |
| 24 |
2018 |
A new tremulane sesquiterpenoid from the fungus Irpex lacteus. |
--- |
| 25 |
2018 |
Antenatal exposure to betamethasone induces placental 11beta-hydroxysteroid dehydrogenase type 2 expression and the adult metabolic disorders in mice. |
IUGR |
| 26 |
2018 |
Comparison of steroidogenic gene expression in mummichog (Fundulus heteroclitus) testis tissue following exposure to aromatizable or non-aromatizable androgens. |
3beta-HSD, cyp11a1, CYP17A1, DHT, MT |
| 27 |
2018 |
Factors impacting on the action of glucocorticoids in patients receiving glucocorticoid therapy. |
ACTH, AI, GCs, HPA |
| 28 |
2018 |
Glucocorticoid activation by 11beta-hydroxysteroid dehydrogenase enzymes in relation to inflammation and glycaemic control in chronic kidney disease: A cross-sectional study. |
CKD, eGFR, THE |
| 29 |
2018 |
Learning pharmacokinetic models for in vivo glucocorticoid activation. |
--- |
| 30 |
2018 |
Monomeric and oligomeric flavanols maintain the endogenous glucocorticoid response in human macrophages in pro-oxidant conditions in vitro. |
IL, MOF, t-BuOOH |
| 31 |
2018 |
Role of tissue-specific steroid metabolism in oral disease: Is there any clinical implication? |
--- |
| 32 |
2018 |
Swimming exercise to control precocious maturation in male seabass (Dicentrarchus labrax). |
3-beta-HSD, AMH, BW, fshR, gsdf1, SL, smc1beta |
| 33 |
2017 |
11beta-Hydroxysteroid Dehydrogenase Type 1 in Obese Subjects With Type 2 Diabetes Mellitus. |
--- |
| 34 |
2017 |
A maternal high-fat, high-sucrose diet has sex-specific effects on fetal glucocorticoids with little consequence for offspring metabolism and voluntary locomotor activity in mice. |
HFHS |
| 35 |
2017 |
A new cadinane sesquiterpenoid from cultures of the Basidiomycete Panus conchatus. |
--- |
| 36 |
2017 |
Changes in 11beta-Hydroxysteroid Dehydrogenase and Glucocorticoid Receptor Expression in Kawasaki Disease. |
GR, KD |
| 37 |
2017 |
Gastroprotective effect of calealactone B: Lack of involvement of prostaglandins, nitric oxide and sulfhydryls. |
NO |
| 38 |
2017 |
In obese mice, exercise training increases 11beta-HSD1 expression, contributing to glucocorticoid activation and suppression of pulmonary inflammation. |
3beta-HSD, GCs, IL, MCP |
| 39 |
2017 |
Knotting nets: Molecular junctions of interconnecting endocrine axes identified by application of the adverse outcome pathway concept. |
AOP, HPA/I, HPG, HPT, StAR |
| 40 |
2017 |
Normalisation of surfactant protein -A and -B expression in the lungs of low birth weight lambs by 21 days old. |
AEC, GR, IUGR, LAMP, LBW, PR, SP |
| 41 |
2017 |
Recent advances in the study of 11beta-Hydroxysteroid dehydrogenase type 2 (11beta-HSD2)Inhibitors. |
AME |
| 42 |
2017 |
The Effects of Sertraline on Fathead Minnow (Pimephales promelas) Growth and Steroidogenesis. |
20beta-HSD, FHM, TRalpha, TRbeta |
| 43 |
2017 |
Transfer and Metabolism of Cortisol by the Isolated Perfused Human Placenta. |
--- |
| 44 |
2016 |
11beta-hydroxysteroid dehydrogenase inhibition as a new potential therapeutic target for alcohol abuse. |
--- |
| 45 |
2016 |
11beta-hydroxysteroid dehydrogenase-1 deficiency alters the gut microbiome response to Western diet. |
--- |
| 46 |
2016 |
Carbenoxolone exposure during late gestation in rats alters placental expressions of p53 and estrogen receptors. |
dg, IUGR |
| 47 |
2016 |
Cortisol metabolism, postnatal depression and weight changes in the first 12 months postpartum. |
--- |
| 48 |
2016 |
Cortisol-Metabolizing Enzymes in Polycystic Ovary Syndrome. |
5alpha-R, 5betaR, BMI, GC-MS, PCOS |
| 49 |
2016 |
Dysregulation of 11beta-hydroxysteroid dehydrogenases: implications during pregnancy and beyond. |
--- |
| 50 |
2016 |
Expression and regulation of 11beta-hydroxysteroid dehydrogenase type 1 in first trimester human decidua cells: Implication in preeclampsia. |
--- |
| 51 |
2016 |
Intraindividual stability of cortisol and cortisone and the ratio of cortisol to cortisone in saliva, urine and hair. |
HPA, ICC |
| 52 |
2016 |
Local cortisol/corticosterone activation in skin physiology and pathology. |
11-DHC, GCs, HPA |
| 53 |
2015 |
Determination of seven selected neuro- and immunomodulatory steroids in human cerebrospinal fluid and plasma using LC-MS/MS. |
CSF, DHEA |
| 54 |
2015 |
Determination of the topology of endoplasmic reticulum membrane proteins using redox-sensitive green-fluorescence protein fusions. |
17beta-HSD, ER, roGFP |
| 55 |
2015 |
Effect of Luteolin on 11Beta-Hydroxysteroid Dehydrogenase in Rat Liver and Kidney. |
EP, GC |
| 56 |
2015 |
Tissue specific regulation of glucocorticoids in severe obesity and the response to significant weight loss following bariatric surgery (BARICORT). |
BMI, OM |
| 57 |
2015 |
Two new sesquiterpenoids from cultures of the basidiomycete Tremella foliacea. |
--- |
| 58 |
2014 |
A mechanism for rapid neurosteroidal regulation of parenting behaviour. |
CBX |
| 59 |
2014 |
Cortisol and cortisone ratio in urine: LC-MS/MS method validation and preliminary clinical application. |
LLOQ |
| 60 |
2014 |
Cross-talk between adipose tissue and the HPA axis in obesity and overt hypercortisolemic states. |
AT, GC, HPA, V-BFD, WAT |
| 61 |
2014 |
Differential expression of 11beta-hydroxysteroid dehydrogenase type 1 and 2 in mild and moderate/severe persistent allergic nasal mucosa and regulation of their expression by Th2 cytokines: asthma and rhinitis. |
--- |
| 62 |
2014 |
Endocrine disruptors and other inhibitors of 11beta-hydroxysteroid dehydrogenase 1 and 2: Tissue-specific consequences of enzyme inhibition. |
EDs |
| 63 |
2014 |
Expression of 11beta-hydroxysteroid dehydrogenase isoforms in canine adrenal glands treated with trilostane. |
--- |
| 64 |
2014 |
Glucocorticoids and renal Na+ transport: implications for hypertension and salt sensitivity. |
--- |
| 65 |
2014 |
Hepatic 11beta-hydroxysteroid dehydrogenase type 1 activity in obesity and type 2 diabetes using a novel triple tracer cortisol technique. |
D cortisol, LND, OND |
| 66 |
2014 |
Insulin, CCAAT/enhancer-binding proteins and lactate regulate the human 11beta-hydroxysteroid dehydrogenase type 2 gene expression in colon cancer cell lines. |
--- |
| 67 |
2014 |
Intrafollicular cortisol levels inversely correlate with cumulus cell lipid content as a possible energy source during oocyte meiotic resumption in women undergoing ovarian stimulation for in vitro fertilization. |
CC, FF, HSL, IVF, LPL |
| 68 |
2014 |
Pharmacophore Model Refinement for 11beta-Hydroxysteroid Dehydrogenase Inhibitors: Search for Modulators of Intracellular Glucocorticoid Concentrations. |
--- |
| 69 |
2014 |
Reductive metabolism of nabumetone by human liver microsomal and cytosolic fractions: exploratory prediction using inhibitors and substrates as marker probes. |
AKR, CBR, MNBO |
| 70 |
2014 |
Simultaneous measurements of cortisol and cortisone in urine and hair for the assessment of 11beta-hydroxysteroid dehydrogenase activity among methadone maintenance treatment patients with LC-ESI-MS/MS. |
--- |
| 71 |
2013 |
11beta-hydroxyandrostenedione, the product of androstenedione metabolism in the adrenal, is metabolized in LNCaP cells by 5alpha-reductase yielding 11beta-hydroxy-5alpha-androstanedione. |
11OH-5alpha-dione, CYP11B1, CYP11B2 |
| 72 |
2013 |
11β-hydroxysteroid dehydrogenases: intracellular gate-keepers of tissue glucocorticoid action. |
MR |
| 73 |
2013 |
7alpha-hydroxylation of dehydroepiandrosterone does not interfere with the activation of glucocorticoids by 11beta-hydroxysteroid dehydrogenase in E(t)C cerebellar neurons. |
7alpha-OH-DHEA, DHEA, H6PDH |
| 74 |
2013 |
Characteristics of novel hair-based biomarker for the activity assessment of 11beta-hydroxysteroid dehydrogenase. |
--- |
| 75 |
2013 |
Environmental stress-induced testis differentiation: androgen as a by-product of cortisol inactivation. |
11-KT, TSD |
| 76 |
2013 |
Expression profiles of cortisol-inactivating enzyme, 11beta-hydroxysteroid dehydrogenase-2, in human epidermal tumors and its role in keratinocyte proliferation. |
BCC, SCC, SK, TPA |
| 77 |
2013 |
Main metabolic pathways of TAK-802, a novel drug candidate for voiding dysfunction, in humans: the involvement of carbonyl reduction by 11beta-hydroxysteroid dehydrogenase 1. |
--- |
| 78 |
2013 |
Ovarian 11beta-hydroxysteroid dehydrogenase (11betaHSD) activity is suppressed in women with anovulatory polycystic ovary syndrome (PCOS): apparent role for ovarian androgens. |
PCO, PCOS |
| 79 |
2013 |
Ovarian localization of 11beta-hydroxysteroid dehydrogenase (11betaHSD): effects of ACTH stimulation and its relationship with bovine cystic ovarian disease. |
COD |
| 80 |
2013 |
Primary male osteoporosis is associated with enhanced glucocorticoid availability. |
MO |
| 81 |
2013 |
Regulation of glucocorticoid metabolism in the boar testis and caput epididymidis by the gonadotrophin-cAMP signalling pathway. |
PKA |
| 82 |
2013 |
Remission of hypertension and electrolyte abnormalities following renal transplantation in a patient with apparent mineralocorticoid excess well documented throughout childhood. |
AME |
| 83 |
2013 |
Synthesis of sterically encumbered 11beta-aminoprogesterone derivatives and evaluation as 11beta-hydroxysteroid dehydrogenase inhibitors and mineralocorticoid receptor antagonists. |
MR |
| 84 |
2013 |
The expression of 11beta-HSDs, GR, and H6PDH in subcutaneous adipose tissue from polycystic ovary syndrome subjects. |
GR, H6PDH, HOMA-IR, HOMA-IS, PCOS, SAT, TNF-alpha |
| 85 |
2012 |
11beta-hydroxysteroid dehydrogenase type 1 is expressed in human sebaceous glands and regulates glucocorticoid-induced lipid synthesis and toll-like receptor 2 expression in SZ95 sebocytes. |
GCs, siRNA, SREBP-1, TLR2 |
| 86 |
2012 |
Distribution of glucocorticoid receptors and 11beta-hydroxysteroid dehydrogenase isoforms in the human inner ear. |
GCs, GRs, MD, SV |
| 87 |
2012 |
Expression of 11beta-hydroxysteroid dehydrogenase type 1 and glucocorticoid receptors in reproductive tissue of male horses at different stages of sexual maturity. |
GCR, GCs, IHC, NAD, qRT-PCR |
| 88 |
2012 |
Gene expression of ACTH, glucocorticoid receptors, 11betaHSD enzymes, LH-, FSH-, GH receptors and aromatase in equine epididymal and testicular tissue. |
FSHR, GAPDH, GCs, GHR, LHR, MC2R |
| 89 |
2012 |
IL-13-induced changes in endogenous glucocorticoid metabolism in the lung regulate the proasthmatic response. |
CBX, GC |
| 90 |
2012 |
Local amplification of glucocorticoids in the aging brain and impaired spatial memory. |
GCs, KO |
| 91 |
2012 |
Mediastinal adipose tissue expresses a pathogenic profile of 11 beta-hydroxysteroid dehydrogenase Type 1, glucocorticoid receptor, and CD68 in patients with coronary artery disease. |
CAD, CAD, GCR |
| 92 |
2012 |
Steroids and their metabolites in CSF from shunt as potential predictors of further disease progression in patients with hydrocephalus and the importance of 11beta-hydroxysteroid dehydrogenase. |
CSF |
| 93 |
2012 |
The effect of glycyrrhetinic acid on pharmacokinetics of cortisone and its metabolite cortisol in rats. |
GA |
| 94 |
2012 |
The in vitro metabolism of cortisol by ovarian follicles of rainbow trout (Oncorhynchus mykiss): comparison with ovulated oocytes and pre-hatch embryos. |
GST, YF |
| 95 |
2012 |
Validation and application of a highly specific and sensitive ELISA for the estimation of cortisone in saliva, urine and in vitro cell-culture media by using a novel antibody. |
--- |
| 96 |
2011 |
11β-Hydroxysteroid dehydrogenase type 1, but not type 2, deficiency worsens acute inflammation and experimental arthritis in mice. |
--- |
| 97 |
2011 |
Age-related changes in corticosteroid receptor expression and monoamine neurotransmitter concentrations in various brain regions of postnatal pigs. |
GR, MR |
| 98 |
2011 |
Cyclopeptide Alkaloids from Ziziphus apetala. |
--- |
| 99 |
2011 |
Distribution of glucocorticoid receptors and 11 beta-hydroxysteroid dehydrogenase isoforms in the rat inner ear. |
CN, DCs, GRs, IHCs, OHCs, PCR, RM, SGCs, SLib, SLig, SV, VHCs, VN |
| 100 |
2011 |
Elevated glucocorticoid metabolism in placental tissue from first trimester pregnancies at increased risk of pre-eclampsia. |
--- |
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