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Abbreviation : 12-HHT
Long Form : 12(S)-hydroxyheptadeca-5Z,8E,10E-trienoic acid
No. Year Title Co-occurring Abbreviation
2020 Cyp2c44 regulates prostaglandin synthesis, lymphangiogenesis, and metastasis in a mouse model of breast cancer. PG, PyMT, WDFY1
2017 Non-steroidal anti-inflammatory drug delays corneal wound healing by reducing production of 12-hydroxyheptadecatrienoic acid, a ligand for leukotriene B4 receptor 2. COXs, NSAIDs
2016 Leukotriene B4 receptor type 2 (BLT2) enhances skin barrier function by regulating tight junction proteins. CLDN4, LTB4, MDCK, TER
2016 The leukotriene B4 receptor BLT2 protects barrier function via actin polymerization with phosphorylation of myosin phosphatase target subunit 1 in human keratinocytes. LTB4, TER
2014 12-Hydroxyheptadecatrienoic acid promotes epidermal wound healing by accelerating keratinocyte migration via the BLT2 receptor. GPCR, LTB4, MMPs, TNF
2014 A turn on and a turn off: BLT1 and BLT2 mechanisms in the lung. LTB4
2013 Cytochrome P4502S1: a novel monocyte/macrophage fatty acid epoxygenase in human atherosclerotic plaques. PG
2013 Leukotriene B4 receptor BLT2 negatively regulates allergic airway eosinophilia. BAL, IFN, IL, LTB4, OVA
2013 Thromboxane A synthase-independent production of 12-hydroxyheptadecatrienoic acid, a BLT2 ligand. COX, TxAS
10  2010 Protective role of the leukotriene B4 receptor BLT2 in murine inflammatory colitis. CXCL9, DSS, IFN, IL, MDCKII, STAT3, TER
11  2008 12(S)-Hydroxyheptadeca-5Z, 8E, 10E-trienoic acid is a natural ligand for leukotriene B4 receptor 2. BLT2, BMMCs