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Abbreviation : 15-HETE
Long Form : 15-hydroxy-5,8,11,13-eicosatetraenoic acid
No. Year Title Co-occurring Abbreviation
2014 Involvement of p38 MAPK in haemozoin-dependent MMP-9 enhancement in human monocytes. MAPKs, MMP-9
2011 Enhancement by LDL of transfer of L-4F and oxidized lipids to HDL in C57BL/6J mice and human plasma. ---
2010 Role of the NF-kappaB transcription pathway in the haemozoin- and 15-HETE-mediated activation of matrix metalloproteinase-9 in human adherent monocytes. MMP-9
2002 The activity of PPAR gamma in primary human trophoblasts is enhanced by oxidized lipids. 13-HODE, 9-HODE
2000 Quantitation of arachidonic acid metabolites in small tissue biopsies by reversed-phase high-performance liquid chromatography. 12-HETE, LTB4, PGE2
1997 Altered responses of human macrophages to lipopolysaccharide by hydroperoxy eicosatetraenoic acid, hydroxy eicosatetraenoic acid, and arachidonic acid. Inhibition of tumor necrosis factor production. 15-HPETE, TNF
1996 Activation of NADPH oxidase required for macrophage-mediated oxidation of low-density lipoprotein. 13-HODE, CGD, HMDM, LDL, NADPH, PMA, SOD
1996 NO synthase and guanylate cyclase inhibitors block modulation of the plasticity of common snail cholinoreceptors by 15-hydroxy-eicosatetraenoic acid. cGMP, NO
1995 Roles of arachidonic acid, lipoxygenases and phosphatases in calcium-dependent modulation of M-current in bullfrog sympathetic neurons. 4-BPB, AA, ETI, LHRH, LO, NDGA
10  1995 The influence of an inhibitor of lipoxygenases on the modulation of the plasticity of cholinoreceptors by 15-HETE. ACh
11  1994 Acetylation of human prostaglandin endoperoxide synthase-2 (cyclooxygenase-2) by aspirin. PGHS
12  1994 Interactions of PGH synthase isozymes-1 and -2 with NSAIDs. NSAIDs, PGHS-1, PGHS-2
13  1994 Pharmacology of prostaglandin endoperoxide synthase isozymes-1 and -2. NSAIDs, PGHS-1, PGHS-2
14  1994 [The effect of a lipoxygenase inhibitor on the modulation of cholinoreceptor plasticity by 15-HETE]. ---
15  1993 Failure of frusemide to increase production of prostaglandin E2 in human nasal mucosa in vivo. PGE2
16  1993 Human alveolar macrophages have 15-lipoxygenase and generate 15(S)-hydroxy-5,8,11-cis-13-trans-eicosatetraenoic acid and lipoxins. HAM, IL-4, LO, LTA4, LTB4
17  1993 Protein kinase C-mediated phospholipase A2 activation, platelet-activating factor generation and prostacyclin release in spontaneously beating rat cardiomyocytes. lysoPC, PAF, PGE2, PKC, PLA2, PMA
18  1993 Release of chemical mediators and inflammatory cell influx during early allergic reaction in the nose: effect of furosemide. PGE2
19  1993 Transmembrane signaling in human polymorphonuclear neutrophils: 15(S)-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoic acid modulates receptor agonist-triggered cell activation. fMLP, G protein, PMN
20  1993 [The effect of a decrease in the mobilization of Ca+ and its chemo-controlled intake into the cytoplasm on the modulation of cholinoreceptor neuronal plasticity in Helix lucorum snails by 15-hydroxyeicosatetraenoic acid]. ChR
21  1992 Suggested mechanism for the formation of 15-hydroxyeicosatrienoic acid by rat epidermal microsomes. 13-HEpETrE, 15-HETrE, 15-HPETE, 15-KETE, 15-KETrE, GC-MS, HPLC
22  1991 Release of 15-hydroxy-5,8,11,13-eicosatetraenoic acid and cysteinyl-leukotrienes in carrageenin-induced inflammation: effect of non-steroidal anti-inflammatory drugs. LT, NSAID, PG, TX
23  1991 [Short and long latent effects of 15-hydroxyeicosatetraenoic acid on the extinction of the acetylcholine-induced inward current in neurons of the Helix lucorum]. ---
24  1990 15(S)-hydroxyeicosatetraenoic acid is the major arachidonic acid metabolite in human bronchi: association with airway epithelium. mono-HETEs
25  1990 Biosynthesis of platelet-activating factor (PAF) in human polymorphonuclear leucocytes. The role of lyso-PAF disposal and free arachidonic acid. 5-HETE, LTB4, MIX, PAF, PMN
26  1990 Effects of changes in oxygen tension on lipoxygenase metabolites. Serum 15-HETE is increased in kittens exposed to hyperoxia. ---
27  1990 Elevated formation of lipoxins in viral antibody-positive rat alveolar macrophages. AM, LX, LXA4, LXB4, RP-HPLC
28  1990 Lipoxygenase inhibitors suppress intracellular calcium rise induced by ionomycin in rat thymocytes. AA, BPB, LO, NDGA, PLA2
29  1990 Metabolism of 15-hydroxy-5,8,11,13-eicosatetraenoic acid by MOLT-4 cells and blood T-lymphocytes. ---
30  1990 Oxygenation of biological membranes by the reticulocyte lipoxygenase. Lack of stoichiometry between oxygen uptake and product formation. 13-HODE
31  1990 Oxygenation of mitochondrial membranes by the erythroid lipoxygenase. Consequences for membrane properties. 13-HODE
32  1990 Transformation of arachidonic acid by 5- and 15-lipoxygenase pathways in bovine adrenal fasciculata cells. 11,14,15-THET, 15-HPETE, 5-HETE
33  1989 Occurrence of the erythroid cell specific arachidonate 15-lipoxygenase in human reticulocytes. ---
34  1988 Ability of 15-hydroxyeicosatrienoic acid (15-OH-20:3) to modulate macrophage arachidonic acid metabolism. ---
35  1987 Arachidonic acid and 15(S)-hydroxy-5,8,11-cis-13-trans-eicosatetraenoic acid modulate human polymorphonuclear neutrophil activation by monocyte derived neutrophil activating factor. AA, LTB4, NAF, PMN
36  1987 Arachidonic acid and its lipoxygenase metabolites stimulate prolactin release in superfused pituitary cells. 5-HETE, LT, TRH
37  1987 Preparative HPLC purification of prostaglandin endoperoxides and isolation of novel cyclooxygenase-derived arachidonic acid metabolites. 15-HPETE, AA, PGG2, PGH2
38  1987 Stimulation of gonadotropin release by arachidonic acid and its lipoxygenase metabolites in superfused pituitary cells. 5-HETE
39  1986 Lipoxin A. Stereochemistry and biosynthesis. 15-HPETE, LXA
40  1986 The occurrence of a lipoxygenase pathway in reticulocytes of various species. SP-HPLC
41  1985 Cell damage unmasks 15-lipoxygenase activity in human neutrophils. ---
42  1985 Characterization and separation of the arachidonic acid 5-lipoxygenase and linoleic acid omega-6 lipoxygenase (arachidonic acid 15-lipoxygenase) of human polymorphonuclear leukocytes. 15-HPETE, 5-HETE, 5-HPETE, RP-HPLC
43  1985 Formation of 15-HETE as a major hydroxyeicosatetraenoic acid in the atherosclerotic vessel wall. ---
44  1985 Inhibition of platelet and neutrophil phospholipase A2 by hydroxyeicosatetraenoic acids (HETES). A novel pharmacological mechanism for regulating free fatty acid release. 12-HETE, 5-HETE, HETEs, PLA2
45  1984 Biosynthesis and metabolism of 15-hydroperoxy-5,8,11,13-eicosatetraenoic acid by human umbilical vein endothelial cells. 15-HPETE, 8,15-diHETE
46  1984 Characterization of lipoxygenase metabolites of arachidonic acid in cultured human skin fibroblasts. 11-HETE, HHT
47  1984 Comparative effects of indomethacin, acetylenic acids, 15-HETE, nordihydroguaiaretic acid and BW755C on the metabolism of arachidonic acid in human leukocytes and platelets. ETYA, HHT, NDGA, RP-HPLC
48  1983 Characterization of 11-HETE and 15-HETE, together with prostacyclin, as major products of the cyclooxygenase pathway in cultured rat aorta smooth muscle cells. 11-HETE, HHT, RSM
49  1983 Modulation of insulin secretion by lipoxygenase products of arachidonic acid. Relation to lipoxygenase activity of pancreatic islets. 12-HETE, 15-HPETE, 5-HETE, BHT, NDGA
50  1983 Non-chemokinetic neutrophil attractants derived from arachidonic acid. 15-HPETE
51  1982 Identification of prostaglandins and other arachidonic acid metabolites in experimental otitis media. AA, HHT, MEM, PGs
52  1981 15-hydroxy-5, 8, 11, 13-eicosatetraenoic acid (15-HETE) formation by rabbit peritoneal tissue. ---
53  1981 15-Hydroxy-5,8,11,13-eicosatetraenoic acid (15-HETE) formation by rabbit peritoneal tissue. ---
54  1981 Arachidonic acid 15-lipoxygenase from rabbit peritoneal polymorphonuclear leukocytes. Partial purification and properties. 15-HPETE, ETYA
55  1980 Identification of 15-hydroxy-5,8,11,13-eicosatetraenoic acid (15-HETE) as a major metabolite of arachidonic acid in human lung. ---
56  1980 Metabolism of linoleic and arachidonic acids in VX2 carcinoma tissue: identification of monohydroxy octadecadienoic acids and monohydroxy eicosatetraenoic acids. 13-HODD, 9-HODD, II-HETE