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Abbreviation : 2',5'-OAS
Long Form : 2',5'-oligoadenylate synthetase
No. Year Title Co-occurring Abbreviation
2012 Suppression of interferon-alpha signaling by hepatitis E virus. HEV, IFN, JAK-STAT, ORF, PKR, Tyk
2010 Evaluation of an attenuated vesicular stomatitis virus vector expressing interferon-beta for use in malignant pleural mesothelioma: heterogeneity in interferon responsiveness defines potential efficacy. IFN-beta, IFNARs, MxA, PKR, VSV
2010 Interferon-lambda induces G1 phase arrest or apoptosis in oesophageal carcinoma cells and produces anti-tumour effects in combination with anti-cancer agents. 5-FU, IFNAR, MHC, MxA, Rb
2009 Local expression of interferon-alpha and interferon receptors in cervical intraepithelial neoplasia. HPV, IFN-alpha
2008 Antiviral activity of type I interferons and interleukins 29 and 28a (type III interferons) against Apeu virus. APEUV, IFNs, IL
2008 In vitro effect of thymosin-alpha1 and interferon-alpha on Th1 and Th2 cytokine synthesis in patients with eAg-negative chronic hepatitis B. IFN-alpha, IL-2, PBMCs, Talpha1, Th1
2008 Novel controlled-release Lemna-derived IFN-alpha2b (Locteron): pharmacokinetics, pharmacodynamics, and tolerability in a phase I clinical trial. PEG-IFN-alpha2b
2007 On the discovery of interferon-inducible, double-stranded RNA activated enzymes: the 2'-5'oligoadenylate synthetases and the protein kinase PKR. ds
2004 Inhibition of infectious human herpesvirus 8 production by gamma interferon and alpha interferon in BCBL-1 cells. HHV-8, IFN-alpha, IFN-gamma, PKR
10  2004 Interferon-gamma-associated responses to woodchuck hepatitis virus infection in neonatal woodchucks and virus-infected hepatocytes. IDO, IFN-gamma, MHC1, pTNF-alpha, RI, TNF-alpha, WHV, WPH
11  2002 Different antiviral activities of IFN-alpha subtypes in human liver cell lines: synergism between IFN-alpha2 and IFN-alpha8. IFN-alpha
12  2002 IFN-beta gene transfer into the central nervous system using bone marrow cells as a delivery system. BBB, CNS, IFN-beta, MS
13  2002 Low expression of interferon-stimulated genes in active multiple sclerosis is linked to subnormal phosphorylation of STAT1. IRF-1, MNCs
14  2002 Relationship between 24-hour rhythm in antiviral effect of interferon-beta and interferon-alpha/beta receptor expression in mice. IFN-beta, IFNAR
15  2001 Geranylgeranylacetone induces antiviral gene expression in human hepatoma cells. GGA, ISGF3, PKR, STAT1, STAT2
16  2001 Structural and biologic characterization of pegylated recombinant IFN-alpha2b. CD, HPSEC, IFN-alpha, LAK, MALDI-MS, NK, PKR
17  2000 Effect of interferon treatment on serum 2',5'-oligoadenylate synthetase levels in hepatitis C-infected patients. IFN
18  2000 Effects of specific mutations in active site motifs of 2',5'-oligoadenylate synthetase on enzymatic activity. IFN
19  2000 Modulation of double-stranded RNA-mediated gene induction by interferon in human umbilical vein endothelial cells. dsRNA, HUVEC, ICAM-1, IFN, IL-6, PKR, TNF-alpha, VCAM-1
20  2000 Pharmacologic effect of recombinant human IFN-alpha, continuously released from a matrix prepared from a polyglycerol ester of fatty acids, on 2',5'-oligoadenylate synthetase activity in murine liver. PGEF, rHuIFN-alpha, TGDP
21  1999 A phase I study of recombinant interferon-beta in patients with advanced malignant disease. AEs, MIU, MTD
22  1999 Biologic and binding activities of IFN-alpha subtypes in ACHN human renal cell carcinoma cells and Daudi Burkitt's lymphoma cells. SFV, VSV
23  1999 Oral prostaglandin (PGE2) therapy for chronic viral hepatitis B and C. HBeAb, HBeAg, HCV, PCA, PGE2
24  1999 Suppression of late asthmatic response by low-dose oral administration of interferon-beta in the guinea pig model of asthma. EAR, IFN-beta, LAR, LDOA, OVA, Rrs
25  1999 The human 2',5'-oligoadenylate synthetase family: interferon-induced proteins with unique enzymatic properties. ds, IFN
26  1998 In vivo induction of the interferon-stimulated protein 2'5'-oligoadenylate synthetase in tumor and peripheral blood cells during IFN-alpha treatment of metastatic melanoma. IFN-alpha, PBMC
27  1998 Production of immunoreactive 2',5'-oligoadenylate synthetase in p48-deficient mice. IFN, ISGF3
28  1998 Ribavirin and interferon alfa-2b in chronic hepatitis C: assessment of possible pharmacokinetic and pharmacodynamic interactions. IFN
29  1998 The target cells of injected type I interferons in mouse liver. IFNs
30  1995 Action of quail and chicken interferons on a quail cell line, QT35. IFN
31  1994 Expression of alpha/beta interferons (IFN-alpha/beta) and their relationship to IFN-alpha/beta-induced genes in lymphocytic choriomeningitis. CNS, LCM
32  1991 In vitro and in vivo 2',5'-oligoadenylate synthetase activity induced by recombinant DNA-derived bovine interferon alpha I1 in bovine alveolar macrophages and blood mononuclear cells. ---