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Abbreviation : 5 alpha-R
Long Form : 5 alpha-reductase
No. Year Title Co-occurring Abbreviation
2004 Anatomical and cellular localization of neuroactive 5 alpha/3 alpha-reduced steroid-synthesizing enzymes in the spinal cord. 3 alpha-HSD, CNS, GM, SC, WM
2004 Quantitative analysis of 5 alpha-reductase inhibitors in DU145 cells using matrix-assisted laser desorption/ ionization time-of-flight mass spectrometry and high-performance liquid chromatography/tandem mass spectrometry. MALDI-TOF MS
2004 Selective non-steroidal inhibitors of 5 alpha-reductase type 1. BPH, DHT
2002 Hypothalamic 5 alpha-reductase and 3 alpha-oxidoreductase activity in the male rat. 3 alpha-OR, 3 alpha-Pr, 5 alpha-Pr, FSH, LH, PR
2001 Immunohistochemical localization of 3 beta-hydroxysteroid dehydrogenase and 5 alpha-reductase in the brain of the African lungfish Protopterus annectens. 3beta-HSD
2000 Elevation of steroid 5 alpha-reductase mRNA levels in rat cerebellum by toluene inhalation: possible relation to GFAP expression. GFAP
1998 5 alpha-reductase isozymes in the central nervous system. DHP, DHT, THP
1998 Activity of 5-alpha-reductase and 17-beta-hydroxysteroid dehydrogenase in the infrainfundibulum of subjects with and without acne vulgaris. 17beta-HSD
1997 5 alpha-reductase deficiency in patients with micropenis. 5 alpha RD, DHT, hCG
10  1997 Comparison between testosterone enanthate-induced azoospermia and oligozoospermia in a male contraceptive study. V. Localization of higher 5 alpha-reductase activity to the reproductive tract in oligozoospermic men administered supraphysiological doses of testosterone. AdiolG, DHT, PGE2, TE
11  1997 Effects of a new 5 alpha reductase inhibitor (epristeride) on human prostate cell cultures. DHT, PSA, RT-PCR, TGF-beta1
12  1997 Effects of finasteride, a type 2 5-alpha reductase inhibitor, on fetal development in the rhesus monkey (Macaca mulatta). DHT, GD, i.v
13  1997 Expression of rat steroid 5 alpha-reductase (isozyme-1) in Spodoptera frugiperda, SF21, insect cells: expression of rat steroid 5 alpha-reductase. 4MA, DHT, r5 alpha R 1
14  1997 Pharmacological and molecular evidence for the expression of the two steroid 5 alpha-reductase isozymes in normal and hyperplastic human prostatic cells in culture. RT-PCR
15  1996 5 alpha-reductase expression by prostate cancer cell lines and benign prostatic hyperplasia in vitro. BPH
16  1996 Comparison between testosterone enanthate-induced azoospermia and oligozoospermia in a male contraceptive study. III. Higher 5 alpha-reductase activity in oligozoospermic men administered supraphysiological doses of testosterone. AdiolG, CRT-DHT, DHT, MCRT, TE
17  1996 Evaluation of men on finasteride. DHT, DRE
18  1996 FCE 28260, a new 5 alpha-reductase inhibitor: in vitro and in vivo effects. DHT
19  1996 Human prostatic cells in culture: different testosterone metabolic profile in epithelial cells and fibroblasts from normal or hyperplastic prostates. 17 beta-OHSDHase
20  1996 In vitro inhibition of testicular delta 5-3 beta-hydroxysteroid dehydrogenase and prostatic 5 alpha-reductase activities in rats and humans by strogen forte extract. delta 5-3 beta-HSD
21  1996 Predominant expression of 5 alpha-reductase type 1 in pubic skin from normal subjects and hirsute patients. DHT
22  1995 Activin and inhibin have opposite effects on steroid 5 alpha-reductase activity in genital skin fibroblasts. DHT, TGF-beta
23  1995 Activity of the type 1 5 alpha-reductase exhibits regional differences in isolated sebaceous glands and whole skin. ---
24  1995 Molecular study of the 5 alpha-reductase type 2 gene in three European families with 5 alpha-reductase deficiency. ---
25  1995 Testosterone metabolism in primary cultures of human prostate epithelial cells and fibroblasts. 17beta-HSD, BPH, DHT
26  1995 [5-alpha-reductases: physiology and pathology]. ---
27  1994 Effect of the in vivo treatment with the synthetic steroid 17 beta-methoxy-17-methyl-(5 alpha)-1 H'-androstane-(3,2-c) pyrazole (17MM) on the in vitro formation of DHT in the epididymis of the rat. 14C-T, 17MM, s.c
28  1994 Inhibition of the activity of 'basic' 5 alpha-reductase (type 1) detected in DU 145 cells and expressed in insect cells. DHT, LSESR
29  1994 Mechanism of action of androgen in hair follicles. 17beta-HSD, DPC, EK, ORSC
30  1994 Photoaffinity labeling of rat liver microsomal steroid 5 alpha-reductase by 2-azido-NADP+. PEG
31  1993 Androgen induction of steroid 5 alpha-reductase may be mediated via insulin-like growth factor-I. DHT, IGF-I
32  1993 Azasteroids as inhibitors of testosterone 5 alpha-reductase in mammalian skin. 4-MA, MPB
33  1993 Effects of transforming growth factor beta and epidermal growth factor on steroid 5 alpha-reductase activity in genital skin fibroblasts. DHT, TGF-beta1
34  1993 Influence of steroid hormones on 5 alpha-reductase activity in female and male genital skin fibroblasts in culture. ---
35  1992 Androgen hydroxysteroid dehydrogenases under the influence of pyridoxine derivatives. ---
36  1992 In vitro study of rat prostate 5 alpha-reductase activity and its inhibition. ---
37  1990 Androgen receptors are differentially distributed between right and left cerebral hemispheres of the fetal male rhesus monkey. AR, AROM, FR, Rt, TMP
38  1989 5 alpha-reductase, aromatase, and androgen receptor levels in the monkey brain during fetal development. AMG, AR, AROM, CAL, CB, CNG, CTX, HRT, MBH, MUS
39  1988 Effect of a 4-methyl-4-aza steroid on androgen metabolism by rat ventral prostate epithelial and stromal cell cultures: selective inhibition of 5 alpha-reductase activity. 17 beta-HSORox, 3 alpha-HSORox, 3 beta-HSORox, DMAA
40  1986 Control of 5 alpha-reduction of testosterone in neuroendocrine tissues of female rats. ---
41  1986 Studies of androgen metabolism and action in cultured hair and skin cells. 17beta-HSD
42  1984 Partial androgen resistance associated with secondary 5 alpha-reductase deficiency: identification of a novel qualitative androgen receptor defect and clinical implications. DHT, GSF