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Abbreviation : AA
Long Form : adjuvant-induced arthritis
No. Year Title Co-occurring Abbreviation
2020 ASIC1a induces synovial inflammation via the Ca2+/NFATc3/ RANTES pathway. ASIC1a, NFATs, RA, RASF
2019 1,25-Dihydroxyvitamin D3 attenuates disease severity and induces synoviocyte apoptosis in a concentration-dependent manner in rats with adjuvant-induced arthritis by inactivating the NF-kappaB signaling pathway. AIASs, PWTL, RA
2019 Andrographolide Ameliorates Rheumatoid Arthritis by Regulating the Apoptosis-NETosis Balance of Neutrophils. AD, NETs, RA
2019 beta2-adrenoceptor signaling reduction is involved in the inflammatory response of fibroblast-like synoviocytes from adjuvant-induced arthritic rats. EPI, FLS, ISO, NE
2019 BMP9 inhibits the proliferation and migration of fibroblast-like synoviocytes in rheumatoid arthritis via the PI3K/AKT signaling pathway. BMP, FLSs, RA
2019 Changes in Radixin Expression and Interaction with Efflux Transporters in the Liver of Adjuvant-Induced Arthritic Rats. IL, p-radixin, SNP, TNF
2019 CP-25 combined with MTX/ LEF ameliorates the progression of adjuvant-induced arthritis by the inhibition on GRK2 translocation. FLS, GRK2, JNK, LEF, MTX, p-ERK
2019 CP-25 exerts anti-angiogenic effects on a rat model of adjuvant-induced arthritis by promoting GRK2-induced downregulation of CXCR4-ERK1/2 signaling in endothelial cells. CXCL12, CXCR4, GRK2, HUVECs, RA
2019 Effects of Qingluo Tongbi Decoction on Gut Flora of Rats with Adjuvant-Induced Arthritis and the Underlying Mechanism. LDA, QLT, RA, WB
10  2019 Emodin ameliorates rheumatoid arthritis by promoting neutrophil apoptosis and inhibiting neutrophil extracellular trap formation. RA
11  2019 In situ hexagonal liquid crystal for intra-articular delivery of sinomenine hydrochloride. ET, ISH, PT, SMH, VEA
12  2019 Methotrexate improves the anti-arthritic effects of Paeoniflorin-6'-O-benzene sulfonate by enhancing its pharmacokinetic properties in adjuvant-induced arthritis rats. Pae
13  2019 Therapeutic effects of gentiopicroside on adjuvant-induced arthritis by inhibiting inflammation and oxidative stress in rats. CFA, GPS, GSH-Px, IL, MDA, PCO, SOD, TNF
14  2018 Development of a Janus Kinase Inhibitor Prodrug for the Treatment of Rheumatoid Arthritis. HPMA, JAK, P-Tofa, RA
15  2018 Effect of phosphodiesterase-5 inhibition on joint and muscle damage in rats with adjuvant arthritis CFA, CL, MDA, PDE, TAC, TOS
16  2018 Fatty oil from Securidaca inappendiculata exerted therapeutic effects on adjuvant-induced arthritis in mice via suppression on fibroblast-like synoviocyte. RA
17  2018 Ferulic acid inhibits interleukin 17-dependent expression of nodal pathogenic mediators in fibroblast-like synoviocytes of rheumatoid arthritis. CYR61, FA, FLS, GM-CSF, IL-17, IL-17RA, OPG, RA, RANKL, STAT-3, Th, TLR3
18  2018 Inhibition of NF-kappaB pathway in fibroblast-like synoviocytes by alpha-mangostin implicated in protective effects on joints in rats suffering from adjuvant-induced arthritis. DR, MG
19  2018 Ketoprofen and MicroRNA-124 Co-loaded poly (lactic-co-glycolic acid) microspheres inhibit progression of Adjuvant-induced arthritis in rats. miR-124, RA, RANKL
20  2018 Metabolomic Analysis of Biochemical Changes in the Serum and Urine of Freund's Adjuvant-Induced Arthritis in Rats after Treatment with Silkworm Excrement. OPLS-DA, PLS-DA, SE, UPLC-Q-TOF-MS
21  2018 The Micro-RNA Expression Profiles of Autoimmune Arthritis Reveal Novel Biomarkers of the Disease and Therapeutic Response. miRNA, RA
22  2018 Triptolide inhibits the inflammatory activities of neutrophils to ameliorate chronic arthritis. RA, TP
23  2017 2K1C-activated Angiotensin II (Ang II) exacerbates vascular damage in a rat model of arthritis through the ATR/ERK1/2 signaling pathway. ACh, Ang II, HUVECs
24  2017 Co-administration of Magnesium Ion Prevents Indomethacin-Induced Intestinal Ulcerogenic Lesions in Adjuvant-Induced Arthritis Rats. IMC, iNOS, NO, RA
25  2017 Differential activation of endocrine-immune networks by arthritis challenge: Insights from colony-specific responses. CPCA, RA, SD
26  2017 Functional role of PPAR-gamma on the proliferation and migration of fibroblast-like synoviocytes in rheumatoid arthritis. FLSs, PPAR, RA
27  2017 Interleukin 17 regulates SHP-2 and IL-17RA/STAT-3 dependent Cyr61, IL-23 and GM-CSF expression and RANKL mediated osteoclastogenesis by fibroblast-like synoviocytes in rheumatoid arthritis. FLS, IL, RA
28  2017 Pharmacokinetics of Morphine in Rats with Adjuvant-induced Arthritis. ABCB1, UGT
29  2017 Protective Effect of Gentianine, a compound from Du Huo Ji Sheng Tang, against Freund's Complete Adjuvant-Induced Arthritis in Rats. DS, FCA, GE, IL-1beta, IL-6, TNF-alpha
30  2017 Stereoselective hepatic disposition of ibuprofen in the perfused liver of rat with adjuvant-induced arthritis. IB, IB-Glu
31  2017 Stereoselective Pharmacokinetics and Chiral Inversion of Ibuprofen in Adjuvant-induced Arthritic Rats. 2-APA, IB, rac
32  2017 Tanshinone IIA ameliorates chronic arthritis in mice by modulating neutrophil activities. NETs, PCR, RA, TIIA
33  2017 The anti-arthritic activity of total glycosides from Pterocephalus hookeri, a traditional Tibetan herbal medicine. MDA, NO, SOD
34  2017 The Impacts of Chrysanthemum indicum Extract on Oxidative Stress and Inflammatory Responses in Adjuvant-Induced Arthritic Rats. CIE, Ctrl, GSH-Px, MDA, MPO, SOD
35  2017 [Wuwei Wentong Chubi Capsule promotes the autophagy in synovial tissue of adjuvant-induced arthritis rats and its mechanism]. CFA, SD, TPT, WWWTCB
36  2017 [Xinfeng Capsule improves pulmonary function of rats with adjuvant-induced arthritis via regulating the expressions of autophagy-related proteins]. AI, Atg, IL, LC3-II, LEF, MC, NC, SD, TNF-alpha, XFC
37  2016 BAFF and its receptors involved in the inflammation progress in adjuvant induced arthritis rats. IL, TGF, TNF
38  2016 beta2-adrenoceptor signaling reduction in dendritic cells is involved in the inflammatory response in adjuvant-induced arthritic rats. AR, DC, ISO, RA
39  2016 Cobrotoxin extracted from Naja atra venom relieves arthritis symptoms through anti-inflammation and immunosuppression effects in rat arthritis model. CTX, FLS
40  2016 Control of autoimmune inflammation by celastrol, a natural triterpenoid. RA
41  2016 CP-25, a novel compound, protects against autoimmune arthritis by modulating immune mediators of inflammation and bone damage. MMP, Pae, RANKL, ROR-gammat
42  2016 Effect of N-Feruloylserotonin and Methotrexate on Severity of Experimental Arthritis and on Messenger RNA Expression of Key Proinflammatory Markers in Liver. AA-MTX, AA-N-f-5HT, CO, MTX, RA
43  2016 JAK1-STAT3 blockade by JAK inhibitor SHR0302 attenuates inflammatory responses of adjuvant-induced arthritis rats and decreases Th17 and total Bcells. ---
44  2016 LncRNAs expression in adjuvant-induced arthritis rats reveals the potential role of LncRNAs contributing to rheumatoid arthritis pathogenesis. CNC network, LncRNAs, RA, RT-PCR
45  2016 Mechanism of Xinfeng Capsule on Adjuvant-Induced Arthritis via Analysis of Urinary Metabolomic Profiles. OPLS-DA, PCA, PLS-DA, XFC
46  2016 MicroRNA-20a negatively regulates expression of NLRP3-inflammasome by targeting TXNIP in adjuvant-induced arthritis fibroblast-like synoviocytes. FLSs, miRNA-20a, RA
47  2016 Recombinant human endostatin inhibits TNF-alpha-induced receptor activator of NF-kappaB ligand expression in fibroblast-like synoviocytes in mice with adjuvant arthritis. FLSs, IkappaBalpha, NF-kappaB, OPG, RA, rh-endostatin, TNF-alpha
48  2016 Role of phyto-stabilised silver nanoparticles in suppressing adjuvant induced arthritis in rats. S-AgNPs, S-AgNPs
49  2016 Urinary metabolite profiling provides potential differentiation to explore the mechanisms of adjuvant-induced arthritis in rats. RA
50  2016 [Up-regulations of Bax and caspase-3 and down-regulation of Bcl-2 after Xinfeng capsule treatment in adjuvant-induced arthritis rats]. FCA, RT-PCR, SD, TGT, XFC
51  2015 Anti-inflammatory effects and pharmacokinetics study of geniposide on rats with adjuvant arthritis. ELISA, FCA, FLS, GE, GJ, IL, p-p38, p38 MAPKs, PK
52  2015 Antinociceptive and anti-inflammatory activities of Schefflera octophylla extracts. RA, RF
53  2015 APRIL promotes proliferation, secretion and invasion of fibroblast-like synoviocyte from rats with adjuvant induced arthritis. FLS, MMP, RA, RT-PCR
54  2015 Colony-Specific Differences in Endocrine and Immune Responses to an Inflammatory Challenge in Female Sprague Dawley Rats. KC/GRO, MCP-1
55  2015 Excessive Interleukin 18 Relate the Aggravation of Indomethacin-Induced Intestinal Ulcerogenic Lesions in Adjuvant-Induced Arthritis Rat. IL, NSAIDs
56  2015 Expression and effects of B-lymphocyte stimulator and its receptors in T cell-mediated autoimmune arthritis. BLyS, DC, IL, RA
57  2015 Pharmacokinetics and Antiinflammatory Effect of a Novel Gel System Containing Ketoprofen Solid Nanoparticles. KET
58  2015 Prenatal alcohol exposure alters steady-state and activated gene expression in the adult rat brain. HPC, PAE, PF, PFC
59  2015 Protective effect of apigenin on Freund's complete adjuvant-induced arthritis in rats via inhibiting P2X7/NF-kappaB pathway. AP, DS, FCA, IL-1beta, IL-6, NF-kappaB, TNF-alpha
60  2015 Suppressive effects of total alkaloids of Lycopodiastrum casuarinoides on adjuvant-induced arthritis in rats. ALC, CFA, COX-2, IL-6, NF, PGE2, SD, TNF-alpha
61  2015 [Effect of Different Processed Products and Extracts of Morinda officinalis Root on Adjuvant-Induced Arthritis in Rats]. IL-1beta, TGT, TNF-alpha
62  2015 [Effect of triptolide on expressions of Notch receptors and ligands in rats with adjuvant- induced arthritis and reduced pulmonary function]. AI, NC
63  2014 Decreased radixin function for ATP-binding cassette transporters in liver in adjuvant-induced arthritis rats. ABC, ERM
64  2014 Distinct alterations in ATP-binding cassette transporter expression in liver, kidney, small intestine, and brain in adjuvant-induced arthritic rats. ABC, P-gp
65  2014 Effect of solid nanoparticle of indomethacin on therapy for rheumatoid arthritis in adjuvant-induced arthritis rat. HP-beta-CD, IMC, MC
66  2014 Ginsenoside metabolite compound K attenuates inflammatory responses of adjuvant-induced arthritis rats. CK
67  2014 Grape polyphenols and propolis mixture inhibits inflammatory mediator release from human leukocytes and reduces clinical scores in experimental arthritis. GPE, IFN-gamma, PR
68  2014 Inhibition of adjuvant-induced arthritis by nasal administration of novel synthetic peptides from heat shock protein 65. ELISA, HSP, IL, PBS, RA, TNF
69  2014 Novel phosphoinositide 3-kinase delta,gamma inhibitor: potent anti-inflammatory effects and joint protection in models of rheumatoid arthritis. CIA, CII, MMP, RA
70  2014 Swertiamarin ameliorates inflammation and osteoclastogenesis intermediates in IL-1beta induced rat fibroblast-like synoviocytes. FLS
71  2014 Targeting alpha- and beta-Adrenergic Receptors Differentially Shifts Th1, Th2, and Inflammatory Cytokine Profiles in Immune Organs to Attenuate Adjuvant Arthritis. AR, DLN, PHEN, PT, RA, SNS, TERB, Th
72  2014 Therapeutic effects of dichloromethane fraction of Securidaca inappendiculata on adjuvant-induced arthritis in rat. ALP, ALT, AST, IL-1, MCP-1, MDA, NAG, NO, SA, SI, SOD, TNF-alpha, VEGF
73  2014 Therapeutic effects of gel ointments containing tranilast nanoparticles on paw edema in adjuvant-induced arthritis rats. TL
74  2014 Xanthones from Securidaca inappendiculata exert significant therapeutic efficacy on adjuvant-induced arthritis in mice. IL-1, MCP-1, MDA, NAG, SA, TNF-alpha, VEGF
75  2014 [Alterations in expression and function of ABC transporters and ERM proteins in inflammation]. ABC, ERM, P-gp
76  2013 Alteration in plasma protein binding properties of propranolol and flurbiprofen during development of adjuvant-induced arthritis in rats. FP, PL
77  2013 Altered sympathetic-to-immune cell signaling via beta₂-adrenergic receptors in adjuvant arthritis. beta-AR, DLNs, EIA
78  2013 Comparative pharmacokinetics study after oral administration of geniposide in normal rats and adjuvant-induced arthritis rats by UPLC-MS/MS. CL, GE, MRT
79  2013 Systemic delivery of small interfering RNA targeting the interleukin-2/15 receptor beta chain prevents disease progression in experimental arthritis. IL, IL-15R, PEI, RA
80  2013 Temporal cytokine expression and the target organ attributes unravel novel aspects of autoimmune arthritis. MHC, RA, WKY
81  2013 [Effect of Xinfeng Capsule on lung function in rats with adjuvant-induced arthritis and its mechanism]. AI, MC, MMF, MTX, NC, PEF, TPT, XFC
82  2013 [The reduced pulmonary function is related to the decreased expression of Treg and Foxp3 in adjuvant-induced arthritis rats]. MC, NC, Treg
83  2013 [Therapeutic effect and hepatotoxicity of Tripterygium wilfordii compound recipe gel on adjuvant-induced arthritis rat]. AST, IL-4, MMP-3, TNF-alpha, TWCG
84  2012 Celastrus treatment modulates antigen-induced gene expression in lymphoid cells of arthritic rats. Bhsp65, DEG, LNC, RA, Tc, Tc, Tw
85  2012 Co-administration of water containing magnesium ion prevents loxoprofen-induced lesions in gastric mucosa of adjuvant-induced arthritis rat. iNOS, NO, NSAIDs
86  2012 Inhibition of pro-inflammatory cytokines in tumour associated macrophages is a potential anti-cancer mechanism of carboxyamidotriazole. CAI, DEX, LLC, TNF-alpha
87  2012 Modified huo-luo-xiao-ling dan suppresses adjuvant arthritis by inhibiting chemokines and matrix-degrading enzymes. HLXL, LNC, MMPs, RA, SAC
88  2012 Norisoboldine, an alkaloid compound isolated from Radix Linderae, inhibits synovial angiogenesis in adjuvant-induced arthritis rats by moderating Notch1 pathway-related endothelial tip cell phenotype. CIA, NOR, RA
89  2012 Preclinical efficacy of sodium narcistatin to reduce inflammation and joint destruction in rats with adjuvant-induced arthritis. DLN, PMBC, RA, SNS, Th
90  2012 Prenatal alcohol exposure alters the course and severity of adjuvant-induced arthritis in female rats. HPA, PAE
91  2012 Prostaglandin E2 binding peptide: a potential modulatory agent which acts through suppressing NF-kappaB signaling in RA. ---
92  2012 Suppression of autoimmune arthritis by Celastrus-derived Celastrol through modulation of pro-inflammatory chemokines. i.p, RA
93  2012 [Fullerene C60 exhibits immunomodulatory activity during adjuvant-induced arthritis in rats]. FC60
94  2011 An altered peptide ligand corresponding to a novel epitope from heat-shock protein 60 induces regulatory T cells and suppresses pathogenic response in an animal model of adjuvant-induced arthritis. APL, HSP60, RA
95  2011 Prostaglandin E(2) binding peptide screened by phage displaying: a new therapeutic strategy in rheumatoid arthritis. ---
96  2011 Suppression of ongoing experimental arthritis by a chinese herbal formula (huo-luo-xiao-ling dan) involves changes in antigen-induced immunological and biochemical mediators of inflammation. Bhsp65, HLXL, RA
97  2011 TACI-Ig induces immune balance of Th cells in MLN via BLyS/APRIL-receptors signaling in rats with adjuvant-induced arthritis. BCMA, BLyS, IFN, IL, MLN, TACI-Ig, TGF, Th, Treg
98  2011 Therapeutic effects of TACI-Ig on rats with adjuvant-induced arthritis via attenuating inflammatory responses. BLyS, CD, Ig
99  2010 Development of a macromolecular prodrug for the treatment of inflammatory arthritis: mechanisms involved in arthrotropism and sustained therapeutic efficacy. FACS, HPMA
100  2010 Effect and mechanism of AR-6 in experimental rheumatoid arthritis. SD