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Abbreviation : ACOX1
Long Form : acyl-CoA oxidase 1
No. Year Title Co-occurring Abbreviation
2019 (5R)-5-hydroxytriptolide ameliorates liver lipid accumulation by suppressing lipid synthesis and promoting lipid oxidation in mice. AST, Cpt1a, FAO, FAs, HFHFr, NAFLD, PPARalpha, SCD1
2019 A microglial cell model for acyl-CoA oxidase 1 deficiency. TREM2, VLCFA
2019 ACOX1 destabilizes p73 to suppress intrinsic apoptosis pathway and regulates sensitivity to doxorubicin in lymphoma cells. ---
2019 Augmenter of liver regeneration protein deficiency promotes hepatic steatosis by inducing oxidative stress and microRNA-540 expression. ALR, miR-540, PMP70, PPAR, rALR
2019 Effect of divergence in residual feed intake on expression of lipid metabolism-related genes in the liver of meat-type ducks1. ACC, ADFI, CPT1A, FAS, FCR, FOXO1, HRFI, LRFI, PPARgamma, RFI, SIRT1, SREBP-1c
2019 Evaluation of the functional quality of rapeseed oil obtained by different extraction processes in a Sprague-Dawley rat model. AEE, AST, FAS, LDL-C, TC, TG
2019 MicroRNA-15a Regulates the Differentiation of Intramuscular Preadipocytes by Targeting ACAA1, ACOX1 and SCP2 in Chickens. ACAA1, IMF, miR-15a, SCP-2
2019 Protein and gene expression of relevant enzymes and nuclear receptor of hepatic lipid metabolism in grazing dairy cattle during the transition period. CPT1A, DGAT1, PPAR-alpha
2018 A PPAR Pan Agonist, MHY2013 Alleviates Age-Related Hepatic Lipid Accumulation by Promoting Fatty Acid Oxidation and Suppressing Inflammation. CPT1, FGF21, NAFLD, PPARs, SD
10  2018 Aerobic Exercise Increases Meteorin-Like Protein in Muscle and Adipose Tissue of Chronic High-Fat Diet-Induced Obese Mice. AMPK, HF, MGL, PGC-1alpha
11  2018 Central leptin regulates heart lipid content by selectively increasing PPAR beta/delta expression. DGAT1, i.c.v, PDK4, SCD1, TAG
12  2018 Effect of rumen-protected B vitamins and choline supplementation on health, production, and reproduction in transition dairy cows. RPBC
13  2018 Functional characterisation of peroxisomal beta-oxidation disorders in fibroblasts using lipidomics. ACBD5, DBP, PEDs
14  2018 SIRT5 inhibits peroxisomal ACOX1 to prevent oxidative damage and is downregulated in liver cancer. HCC, SIRT5
15  2017 Analysis of molecular mechanisms of 5-fluorouracil-induced steatosis and inflammation in vitro and in mice. 5-FU, HMOX1, JNK
16  2017 hsa-miR-29c-3p regulates biological function of colorectal cancer by targeting SPARC. ACAA1, COL12A1, COL1A1, COL1A2, COL4A1, COL5A2, CPT2, CRC, GEO, qRT-PCR, SQRDL, TST
17  2017 Impact of polyunsaturated and saturated fat overfeeding on the DNA-methylation pattern in human adipose tissue: a randomized controlled trial. CpG, FABP1, FABP2, FAT1, IL-6, INSR, MAPK7, MC2R, MCHR1, NEGR1, POMC, PPARGC1A, PUFAs, SFAs, TNF
18  2017 SIRT1 suppresses colorectal cancer metastasis by transcriptional repression of miR-15b-5p. CRC, FAO, SIRT1
19  2017 Specific Inhibition of Acyl-CoA Oxidase-1 by an Acetylenic Acid Improves Hepatic Lipid and Reactive Oxygen Species (ROS) Metabolism in Rats Fed a High Fat Diet. FAO, ROS
20  2016 Docosahexaenoic Acid Ameliorates Fructose-Induced Hepatic Steatosis Involving ER Stress Response in Primary Mouse Hepatocytes. ACC, DHA, ER, FAS, GRP78, NAFLD, PBA, TG, TM
21  2016 Expression of lipid metabolism-related proteins in breast phyllodes tumors. CPT-1, DFS, FABP4, FASN, HSL, OS, PT
22  2016 Maternal rumen-protected methionine supplementation and its effect on blood and liver biomarkers of energy metabolism, inflammation, and oxidative stress in neonatal Holstein calves. CON, CPT1A, FBP1, FOXO1, GR, INSR, MET, PCK1, RPM, SREBF1
23  2016 Structural characterization of acyl-CoA oxidases reveals a direct link between pheromone biosynthesis and metabolic state in Caenorhabditis elegans. ---
24  2015 A randomized, placebo-controlled phase III trial of masitinib plus gemcitabine in the treatment of advanced pancreatic cancer. HR, OS, PDAC
25  2015 Diet rich in Docosahexaenoic Acid/Eicosapentaenoic Acid robustly ameliorates hepatic steatosis and insulin resistance in seipin deficient lipodystrophy mice. ChREBP, CPT, DHA, EPA, FAS, GLU, HDL-C, IRS-1, n-3 PUFAs, NC, PPARalpha, SCD1, SKO, TC, TG
26  2015 Differential expression of lipid metabolism-related proteins in different breast cancer subtypes. FABP4, FASN, HER2, HSL, IHC, PLIN1, TNBC
27  2015 Effect of multiple binge alcohol on diet-induced liver injury in a mouse model of obesity. ALD, Col1, HFD, NAFLD, PPARalpha, Q-PCR, SCD-1, SREBP-1, TGF-beta, TNF-alpha
28  2015 Expression of Lipid Metabolism-Related Proteins in Metastatic Breast Cancer. FASN, HSL, PLIN1
29  2015 The peroxisomal protein import machinery displays a preference for monomeric substrates. UOX
30  2014 A simple and sensitive method for the determination of fibric acids in the liver by liquid chromatography. ---
31  2014 Decreased liver peroxisomal beta-oxidation accompanied by changes in brain fatty acid composition in aged rats. old, PPARalpha, VLCFAs
32  2014 Elevated tissue omega-3 fatty acid status prevents age-related glucose intolerance in fat-1 transgenic mice. ACC, FAS, G6Pase, PEPCK, PTT, PUFA
33  2014 Hugan Qingzhi medication ameliorates hepatic steatosis by activating AMPK and PPARalpha pathways in L02 cells and HepG2 cells. AMPK, AST, CPT-1, FFA, HQT, LDH, MDA, PPARalpha, qRT-PCR, SOD, SREBP-1, T-AOC, TG
34  2014 N-3 long-chain PUFA supplementation prevents high fat diet induced mouse liver steatosis and inflammation in relation to PPAR-alpha upregulation and NF-kappaB DNA binding abrogation. n-3 LCPUFAs, NF-kappaB, PPAR-alpha, TNF-alpha
35  2014 Uridine prevents fenofibrate-induced fatty liver. LCFA, VLCFA
36  2013 Breed and dietary linseed affect gene expression of enzymes and transcription factors involved in n-3 long chain polyunsaturated fatty acids synthesis in longissimus thoracis muscle of bulls. FA, L-PBE, LC, LT, LXR
37  2013 Conjugated linoleic acid isomers and their precursor fatty acids regulate peroxisome proliferator-activated receptor subtypes and major peroxisome proliferator responsive element-bearing target genes in HepG2 cell model. DMSO, FAs, FAT, GAPDH, GLUT2, L-FABP, PBE, PPAR, PPRE, qRT-PCR
38  2013 Exercise facilitates the action of dietary DHA on functional recovery after brain trauma. 4-HHE, BDNF, DHA, iPLA2, mFPI, STX3, TBI, TrkB
39  2013 Green tea polyphenols alleviate obesity in broiler chickens through the regulation of lipid-metabolism-related genes and transcription factor expression. ATGL, CPT I, GTPs, LPL, PPARalpha
40  2013 Tissue-specific transcriptional modulation of fatty acid-binding protein genes, fabp2, fabp3 and fabp6, by fatty acids and the peroxisome proliferator, clofibrate, in zebrafish (Danio rerio). FAs, PPAR, PPRE
41  2012 Sustained activation of PPARalpha by endogenous ligands increases hepatic fatty acid oxidation and prevents obesity in ob/ob mice. ER, PPARalpha
42  2010 Modulation of acute steroidogenesis, peroxisome proliferator-activated receptors and CYP3A/PXR in salmon interrenal tissues by tributyltin and the second messenger activator, forskolin. cAMP, PPAR, PXR
43  2010 Reversal of mouse Acyl-CoA oxidase 1 (ACOX1) null phenotype by human ACOX1b isoform [corrected]. PPARalpha
44  2009 Peroxisomal and mitochondrial status of two murine oligodendrocytic cell lines (158N, 158JP): potential models for the study of peroxisomal disorders associated with dysmyelination processes. ---
45  2007 Association of the polymorphism in GYS1 and ACOX1 genes with meat quality traits in pigs. QTL
46  2007 Biochemical characterization of two functional human liver acyl-CoA oxidase isoforms 1a and 1b encoded by a single gene. ---
47  2004 Hepatic gene expression profiles in a long-term high-fat diet-induced obesity mouse model. Acs2, FASN, GSTs, HFD, HSPs, LFD, SQLE