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Abbreviation : ACT
Long Form : 1-antichymotrypsin
No. Year Title Co-occurring Abbreviation
2019 Circulating inflammatory biomarkers are related to cerebrovascular disease in older adults. CI, CRP, CVD, IL-6, OR, WMH
2018 Acute-phase response and its biomarkers in acute and chronic urticaria. AGP, alpha 2M, APP, AT, AU, Cp, CRP, Hp, Tf
2018 alpha1-Antichymotrypsin Present in Therapeutic C1-Inhibitor Products Competes with Selectin-Sialyl LewisX Interaction. sLeX
2018 Label-Free Quantitative Proteomics Identifies Novel Plasma Biomarkers for Distinguishing Pulmonary Tuberculosis and Latent Infection. AGP1, CART, LC, PTB, TB
2017 Alpha-1 antichymotrypsin is involved in astrocyte injury in concert with arginine-vasopressin during the development of acute hepatic encephalopathy. ALF, AVP, BAL, EC, HE
2017 Circulating inflammatory biomarkers in relation to brain structural measurements in a non-demented elderly population. CRP, IL-6, MRI
2017 Sample preparation of serum to allow capillary electrophoresis analysis of prostate specific antigen isoforms. CD, CZE, fPSA, PSA
2017 Simvastatin ameliorate memory deficits and inflammation in clinical and mouse model of Alzheimer's disease via modulating the expression of miR-106b. AD, APP, BACE1, ELISA, IL-1beta, IL-6, LncRNA, MWM, TNF-alpha
2017 Urinary haptoglobin, alpha-1 anti-chymotrypsin and retinol binding protein identified by proteomics as potential biomarkers for lupus nephritis. ANR, AR, ELISA, HAP, ID, RBP, SLE, SLEDAI
10  2016 Low-grade inflammation predicts persistence of depressive symptoms. CES-D, CRP, IL
11  2016 Pancreatic-type Acinar Cell Carcinoma of the Stomach Included in Multiple Primary Carcinomas. ACC
12  2016 Serum protein profiling in diffuse large B-cell lymphoma. CD14, DLBCL, ECM1, WHO
13  2015 Association between alpha-1 antichymotrypsin gene A/T polymorphism and primary intracerebral hemorrhage: a meta-analysis. ORs, PICH, SCIE
14  2015 Design and characterization of a novel human Granzyme B inhibitor. GrB, RCL
15  2015 Is Alpha-1 Antichymotrypsin Gene Polymorphism a Risk Factor for Primary Intracerebral Hemorrhage? A Case-Control Study and Meta-Analysis. ---
16  2015 Markers of iron status are associated with stage of pregnancy and acute-phase response, but not with parity among pregnant women in Guinea-Bissau. CRP, sTfR
17  2014 Apolipoproteins E and J interfere with amyloid-beta uptake by primary human astrocytes and microglia in vitro. AAPs, AD, SAP-C1q
18  2014 Plasma levels of alpha-1-antichymotrypsin are elevated in patients with chronic heart failure, but are of limited prognostic value. HF
19  2013 Alpha 1-Antichymotrypsin, an Inflammatory Protein Overexpressed in the Brains of Patients with Alzheimer's Disease, Induces Tau Hyperphosphorylation through c-Jun N-Terminal Kinase Activation. AD, IL-1beta, JNK
20  2013 Genetic factors regulating inflammation and DNA methylation associated with prostate cancer. GNMT, IL, PCa, SNPs, VEGF
21  2013 Post-transcriptional regulation of alpha-1-antichymotrypsin by microRNA-137 in chronic heart failure and mechanical support. HF, LVADs, miRs
22  2013 Recurrent intracerebral hemorrhage in patients with hypertension is associated with APOE gene polymorphism: a preliminary study. APOE, ICH
23  2013 The association of ACT -17 A/T polymorphism with Alzheimer's disease: a meta-analysis. AD, OR, RE
24  2012 Association between alpha1-antichymotrypsin signal peptide -15A/T polymorphism and the risk of Alzheimer's disease: a meta-analysis. AD, CI, LOAD, ORs
25  2012 Combination of plasma biomarkers and clinical data for the detection of sporadic Alzheimer's disease. AD
26  2012 Novel application of Ag nanoclusters in fluorescent imaging of human serum proteins after native polyacrylamide gel electrophoresis (PAGE). PAGE
27  2012 The effect of amyloid associated proteins on the expression of genes involved in amyloid-beta clearance by adult human astrocytes. AAPs, AD, IDE, MARCO, NEP, SAP, SCARB1
28  2010 Altered glycosylation profile of purified plasma ACT from Alzheimer's disease. AD, CTR
29  2010 Astrocytic A beta 1-42 uptake is determined by A beta-aggregation state and the presence of amyloid-associated proteins. APOE, SAP
30  2010 Development of a sensitive detection method of cancer biomarkers in human serum (75%) using a quartz crystal microbalance sensor and nanoparticles amplification system. PSA
31  2010 Gene-gene and gene - clinical factors interaction in acute myocardial infarction: a new detailed risk chart. AMI, AutoCM, IFN, IL, SNP, TNF
32  2010 Homocysteine and inflammation: predictors of cognitive decline in older persons? CRP, IL-6
33  2010 Identification and characterization of a misfolded monomeric serpin formed at physiological temperature. ---
34  2010 Is there an association of regulatory region polymorphism in the alpha-1-antichymotrypsin gene with sporadic Alzheimer's disease in the northern Han-Chinese population? AD, SAD, SNP
35  2010 Potential biomarkers of muscle injury after eccentric exercise. C1 Inh
36  2010 Protein misfolding and obstructive lung disease. A1AT
37  2010 [Microarray analysis of human primary astrocytes activated by beta amyloid peptide and alpha1-antichymotrypsin]. IL-6, LPS, TNF-alpha
38  2009 A novel technique for simultaneous bilateral brain infusions in a mouse model of neurodegenerative disease. AD, APOE, APP
39  2009 Acute- phase response and iron status markers among pulmonary tuberculosis patients: a cross-sectional study in Mwanza, Tanzania. APR, PTB, sTfR
40  2009 APOE, ACT and CHRNA7 genes in the conversion from amnestic mild cognitive impairment to Alzheimer's disease. AD, MCI, OR
41  2009 Binding and uptake of A beta1-42 by primary human astrocytes in vitro. AD, CLSM
42  2009 CSF levels of PSA and PSA-ACT complexes in Alzheimer's disease. AD, CSF, FTLD, MCI, PSA, RT-PCR
43  2009 Different altered stage correlative expression of high abundance acute-phase proteins in sera of patients with epithelial ovarian carcinoma. AAT, APPs, CLU, EOCa, HAP, LRG
44  2009 The acute phase response to parturition: a cross-sectional study in Zimbabwe. CRP
45  2008 Alpha 1 antichymotrypsin genotype is associated with increased risk of prostate carcinoma and PSA levels. BHP, PCa, PSA, SNP
46  2008 Alpha-1 antichymotrypsin gene signal peptide a/t polymorphism and primary intracerebral hemorrhage. PICH
47  2008 Elevated plasma levels of alpha-1-anti-chymotrypsin in age-related cognitive decline and Alzheimer's disease: a potential therapeutic target. AD, APOE, CIND, CSF, ELISA
48  2008 Profiling of serum and tissue high abundance acute-phase proteins of patients with epithelial and germ line ovarian carcinoma. CLU
49  2008 Purification of alpha1-antichymotrypsin from human plasma with recombinant M. catarrhalis ubiquitous surface protein A1. Usp
50  2008 [The assessment of acute phase proteins as prognostic factors in patients surgically treated for non-small cell lung cancer]. AGP, APP, AT, Cp, CRP, Hp, NSCLC, Tf
51  2007 Contribution of metabolic syndrome components to cognition in older individuals. CRP
52  2007 Effects of Alzheimer's peptide and alpha1-antichymotrypsin on astrocyte gene expression. ---
53  2007 Identification and validation of novel CSF biomarkers for early stages of Alzheimer's disease. 2-D DIGE, AD, ATIII, CSF, ZAG
54  2007 Plasma levels of alpha1-antichymotrypsin and secretory leukocyte proteinase inhibitor in healthy and chronic obstructive pulmonary disease (COPD) subjects with and without severe alpha1-antitrypsin deficiency. AAT, COPD, SLPI
55  2007 Systemic markers of inflammation and cognitive decline in old age. APOE, CRP, IL-6
56  2006 Alpha-1-antichymotrypsin (ACT or SERPINA3) polymorphism may affect age-at-onset and disease duration of Alzheimer's disease. AAO, AD
57  2006 Alpha1-antichymotrypsin, an inflammatory protein overexpressed in Alzheimer's disease brain, induces tau phosphorylation in neurons. APP, ERK
58  2006 Failure of twice-weekly iron supplementation to increase blood haemoglobin and serum ferritin concentrations: results of a randomized controlled trial. Hb, SF
59  2006 Inflammatory markers and loss of muscle mass (sarcopenia) and strength. CRP, IL
60  2006 Microheterogeneity of acute phase proteins in patients with ulcerative colitis. AGP, CIAE, CRP, Tf, TIBC, UC
61  2006 Mutant recombinant serpins as highly specific inhibitors of human kallikrein 14. AAT, hK14, hK2, RCL
62  2006 Nuclear factor-1-X regulates astrocyte-specific expression of the alpha1-antichymotrypsin and glial fibrillary acidic protein genes. AP-1, GFAP
63  2006 Relationships between biochemical bone turnover markers, season, and inflammatory status indices in prepubertal Gambian boys. CRP
64  2006 Serum alpha-2-macroglobulin, antitrypsin and antichymotrypsin activities in patients receiving treatment with cyclosporine. AT
65  2006 The effects of macrophage migratory inhibitory factor on acute-phase protein production in primary human hepatocytes. CRP, MIF
66  2006 [Evaluation of chosen parameters of acute-phase reaction in children during pseudocroup according to their age]. AGP, AT, Cp, Hp, Tf
67  2006 [Evaluation of selected acute phase proteins in patients with metabolic syndrome]. AGP, alpha 2M, Cp, CRP, Hp
68  2006 [Glycosylation profile of selected acute phase proteins in children with chronic tonsillitis and allergic symptoms]. AGP
69  2005 A new promoter polymorphism in the alpha-1-antichymotrypsin gene is a disease modifier of Alzheimer's disease. AD, APOE, EOAD
70  2005 Acute phase proteins serum concentrations in children are related to urinary iodine excretion. A2m, AGP, APP, AT, beta2-MG, Cp, CRP, Hp, Tf
71  2005 Alpha-1-antichymotrypsin gene polymorphism and susceptibility to multiple system atrophy (MSA). MSA
72  2005 Astrocyte- and hepatocyte-specific expression of genes from the distal serpin subcluster at 14q32.1 associates with tissue-specific chromatin structures. DHSs, Kal, PCI
73  2005 Circadian rhythm of acute phase proteins under the influence of bright/dim light during the daytime. AGP, APP, Cp, CRP, Hp, Tf
74  2005 Ibuprofen suppresses interleukin-1beta induction of pro-amyloidogenic alpha1-antichymotrypsin to ameliorate beta-amyloid (Abeta) pathology in Alzheimer's models. AD, NSAIDs
75  2005 Post-stroke dementia is associated with alpha(1)-antichymotrypsin polymorphism. A/T, A/T, A/T, IQCODE, PRESD, PSD
76  2005 Tumor-host interactions contribute to the elevated expression level of alpha1-antichymotrypsin in metastatic breast tumor xenografts. ---
77  2005 [Study of alpha1-antichymotrypsin (ACT) in prostatic carcinoma]. PSA
78  2004 Aberrant expression of acute-phase reactant proteins in sera and breast lesions of patients with malignant and benign breast tumors. AAT, BC, ELISA, FDB
79  2004 Allele-specific overexpression in astrocytes of an Alzheimer's disease associated alpha-1-antichymotrypsin promoter polymorphism. AD, OSM, SP
80  2004 alpha-1-Antichymotrypsin polymorphism in the gene promoter region affects survival and synapsis loss in Alzheimer's disease. AD, Apo E, MF
81  2004 Cerebral amyloid angiopathy and gene polymorphisms. AD, APOE, CAA, NEP, PS1, TGF
82  2004 Identification of residual structure within denatured antichymotrypsin: implications for serpin folding and misfolding. GdnHCl
83  2004 mRNA expression level of estrogen-inducible gene, alpha 1-antichymotrypsin, is a predictor of early tumor recurrence in patients with invasive breast cancers. HR, STC2
84  2004 The homozygote AA genotype of the alpha1-antichymotrypsin gene may confer protection against early-onset Parkinson's disease in women. PD
85  2004 [ACT/AA polymorphism could duplicate the APOE*epsilon4-associated Alzheimer's disease risk]. AD, CI, OR
86  2004 [Significance of alpha1-antichymotrypsin (ACT) in early diagnosis of intra-amniotic infection (IAI)]. IAI
87  2003 Alzheimer's peptide and serine proteinase inhibitors in glaucoma and exfoliation syndrome. AAT, AD, PEX
88  2003 Apolipoprotein E, angiotensin-converting enzyme and alpha-1-antichymotrypsin genotypes are not associated with post-stroke dementia. ACE, PSD, VD
89  2003 Distribution and secretory pathways of prostate specific antigen, alpha1-antichymotrypsin and prostate secretory granules in prostate cancers. ANOVA, PSA, PSG
90  2003 Evaluation of an automated chemiluminescent immunoassay for complexed PSA on the Bayer ACS:180 system. cPSA, CV, fPSA, PSA
91  2003 Plasma and cerebrospinal fluid alpha1-antichymotrypsin levels in Alzheimer's disease: correlation with cognitive impairment. AD
92  2003 The expression of selected immunocytochemical diagnostic markers in the case of chondrosarcoma with a mesenchymal component. DChSa, MFH
93  2003 The selective inhibition of serpin aggregation by the molecular chaperone, alpha-crystallin, indicates a nucleation-dependent specificity. alpha 1-AT, sHsps
94  2003 The serpins alpha-1-antitrypsin and alpha-1-antichymotrypsin specifically interact with immunophilins. AT
95  2003 Three immunoassays based on monoclonal antibodies specific for prostate specific antigen (PSA), alpha-1-antichymotrypsin (ACT), and the PSA-ACT complex. BPH, ELISA, mAbs, PSA
96  2003 Use of biomarkers of sub-clinical infection, nutrition and neonatal maturity to interpret plasma retinol in Nigerian neonates. AGP, APP
97  2003 White cell scanning for inflammatory bowel disease: are biochemical markers useful referral criteria? AGP, CRP, IBD
98  2003 [Evaluation of acute phase proteins in hypertensive and obese patients]. AGP, APP, CRP, RC
99  2003 [Influence of tonsillectomy in adults on the concentration and glycosylation profile of acute phase proteins]. a.ph.s.p, AGP, alpha 2M, ch.t, Ig, Tf
100  2003 [Interaction of duodenase with human blood serpins]. alpha 1-PI