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Abbreviation : AICAR
Long Form : activator
No. Year Title Co-occurring Abbreviation
2021 Empagliflozin Alleviates Hepatic Steatosis by Activating the AMPK-TET2-Autophagy Pathway in vivo and in vitro. AMPK, MAFLD, T2DM, TET2
2020 AMPK activation ameliorates fine particulate matter-induced hepatic injury. BAT, FA, Shanghai-METAS
2020 Effect of central JAZF1 on glucose production is regulated by the PI3K-Akt-AMPK pathway. Ad-JAZF1, HFD, HGP, HVG, INSR, JAZF1, MBH, PIP3
2020 Metformin Suppresses Cancer Stem Cells through AMPK Activation and Inhibition of Protein Prenylation of the Mevalonate Pathway in Colorectal Cancer. AMPK, CRC, CSCs, MVA
2019 AMPK activation attenuates inflammatory response to reduce ambient PM2.5-induced metabolic disorders in healthy and diabetic mice. Shanghai-METAS, T2DM, VAT
2019 Anti-insulin resistance effects of salidroside through mitochondrial quality control. HFD, IR, MQC, ROS
2019 Elevated p70S6K phosphorylation in rat soleus muscle during the early stage of unloading: Causes and consequences. ---
2019 Gut ghrelin regulates hepatic glucose production and insulin signaling via a gut-brain-liver pathway. Ad-shNR1, AMPK, GIR, HGP, NMDA, NTS, PEC
2018 Combination therapy of lovastatin and AMP-activated protein kinase activator improves mitochondrial and peroxisomal functions and clinical disease in experimental autoimmune encephalomyelitis model. AMPK, MS
10  2018 Involvement of adenosine monophosphate activated kinase in interleukin-6 regulation of steroidogenic acute regulatory protein and cholesterol side chain cleavage enzyme in the bovine zona fasciculata and zona reticularis. AMP, IL-6, p-AMPK, SF-1, StAR, ZF, ZR
11  2017 AMPK improves gut epithelial differentiation and barrier function via regulating Cdx2 expression. AMPK, CDX2
12  2017 Rapid decline in MyHC I(beta) mRNA expression in rat soleus during hindlimb unloading is associated with AMPK dephosphorylation. AMPK, HDAC, HU, MyHC
13  2016 Cardiotrophin-1 decreases intestinal sugar uptake in mice and in Caco-2 cells. CT-1
14  2016 Deficiency in the anti-aging gene Klotho promotes aortic valve fibrosis through AMPKα-mediated activation of RUNX2. AVF, FAVD, HFD, KL
15  2016 Pretreatment of rats with increased bioavailable berberine attenuates cerebral ischemia-reperfusion injury via down regulation of adenosine-5'monophosphate kinase activity. BBR, IR
16  2014 AMPK activation ameliorates Alzheimer's disease-like pathology and spatial memory impairment in a streptozotocin-induced Alzheimer's disease model in rats. AD, ICV-STZ
17  2014 Novel strategy for successful long-term hematopoietic recovery after transplanting a limited number of hematopoietic stem/progenitor cells. AMPK, HSPCs, mTORC1
18  2012 Activation of AMP-activated protein kinase inhibits albumin-induced endoplasmic reticulum stress and apoptosis through inhibition of reactive oxygen species. AMPK, ER, PPARgamma, ROS
19  2011 Dynamic alteration of adiponectin/adiponectin receptor expression and its impact on myocardial ischemia/reperfusion in type 1 diabetic mice. AMPK, MI/R, T1DM
20  2010 AMPK enhances the expression of pancreatic duodenal homeobox-1 via PPARalpha, but not PPARgamma, in rat insulinoma cell line INS-1. AMPK, PDX-1
21  2010 Suppression effects of AICAR on insulin secretion involved in peroxisome proliferator-activated receptor gamma changes in INS-1 cells. AMPK, BADGE, GSIS, PPAR
22  2009 Metformin prevents progression of heart failure in dogs: role of AMP-activated protein kinase. AMPK