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Abbreviation : AP-2
Long Form : activator protein-2
No. Year Title Co-occurring Abbreviation
2021 In vitro and in silico assessment of the effect of WWOX expression on invasiveness pathways associated with AP-2 transcription factors in bladder cancer. WWOX
2019 The biological characteristics of transcription factors AP-2alpha and AP-2gamma and their importance in various types of cancers. lncRNA, TF
2018 Activator Protein-2beta Promotes Tumor Growth and Predicts Poor Prognosis in Breast Cancer. ---
2018 Conditional Deletion of AP-2alpha and AP-2beta in the Developing Murine Retina Leads to Altered Amacrine Cell Mosaics and Disrupted Visual Function. ---
2018 Functional characterization of the Sox2, c-Myc, and Oct4 promoters. ---
2018 Kahweol inhibits proliferation and induces apoptosis by suppressing fatty acid synthase in HER2-overexpressing cancer cells. FASN, HER2, mTOR, PEA3, SREBP-1c
2018 TFAP2C regulates transcription in human naive pluripotency by opening enhancers. ---
2016 Epigenetic programming of Dnmt3a mediated by AP2alpha is required for granting preadipocyte the ability to differentiate. AP2alpha, CI
2016 Use of molecular biomarkers to estimate manganese requirements for broiler chickens from 22 to 42 d of age. MnSOD, Sp1
10  2015 A Positive Feedback Loop between Glial Cells Missing 1 and Human Chorionic Gonadotropin (hCG) Regulates Placental hCGbeta Expression and Cell Differentiation. cAMP, GBS1, GCM1, hCG, PKA
11  2015 Analysis of genetic variations across regulatory and coding regions of kappa-casein gene of Indian native cattle (Bos indicus) and buffalo (Bubalus bubalis). kappa-CN, LD, PMF, TFBSs, TFs
12  2014 AP2 suppresses osteoblast differentiation and mineralization through down-regulation of Frizzled-1. BMSCs, FZD1, hFOB
13  2014 Silencing of CHD5 gene by promoter methylation in leukemia. CHD5, DAC
14  2013 Ectopic expression of transcription factor AP-2delta in developing retina: effect on PSA-NCAM and axon routing. PSA-NCAM
15  2013 PuF, an antimetastatic and developmental signaling protein, interacts with the Alzheimer's amyloid-beta precursor protein via a tissue-specific proximal regulatory element (PRE). AD, APP, EMSA, PRE, SNP, Sp1
16  2012 AP-2beta regulates amyloid beta-protein stimulation of apolipoprotein E transcription in astrocytes. AD, APOE, beta-AR
17  2012 Potential association of DCBLD2 polymorphisms with fall rates of FEV(1) by aspirin provocation in Korean asthmatics. AERD, ATA, DCBLD2, TFAP2A
18  2011 Transcription factor AP2 regulates human inhibin alpha subunit gene expression during in vitro trophoblast differentiation. ---
19  2010 Dietary manganese modulates expression of the manganese-containing superoxide dismutase gene in chickens. Mn, MnSOD, MnSOD-BP, Sp1
20  2010 Interference with activator protein-2 transcription factors leads to induction of apoptosis and an increase in chemo- and radiation-sensitivity in breast cancer cells. GO
21  2010 PACAP-regulated phenylethanolamine N-methyltransferase gene expression. PACAP, PNMT, Sp1
22  2010 Polymorphisms in the bovine lactoferrin promoter are associated with reproductive performance and somatic cell count. Sp1
23  2010 [Dual role of transcription factor AP-2 in carcinogenesis]. ---
24  2009 Activator protein-2 impairs the invasion of a human extravillous trophoblast cell line. EVTs
25  2009 c-FLIPL regulates PKC via AP-2 to inhibit Bax-mediated apoptosis induced by HIV-1 gp120 in Jurkat cells. PKC
26  2009 Identification of target genes of transcription factor activator protein 2 gamma in breast cancer cells. AP-2gamma, ChIP
27  2009 Ku proteins interact with activator protein-2 transcription factors and contribute to ERBB2 overexpression in breast cancer cell lines. ChIP, GST
28  2009 Transcription factor specificity protein 1 (SP1) and activating protein 2alpha (AP-2alpha) regulate expression of human KCTD10 gene by binding to proximal region of promoter. AP-2alpha, PDIP1, Sp1
29  2008 Cloning and functional characterization of the 5' regulatory region of ovine Hormone Sensitive Lipase (HSL) gene. 5'-UTR, ATGL, cAMP, CBFs, CRE, FSE, GR, GRE, HSL, IRE, ovHSL, PKA, Sp1
30  2008 Differential regulation of ErbB2 expression by cAMP-dependent protein kinase in tamoxifen-resistant breast cancer cells. PEA3, PKA, TAM, TAMR-MCF-7
31  2008 Epigenetic regulation of kappa opioid receptor gene in neuronal differentiation. KOR, NGF
32  2008 Mutations in the SOD2 promoter reveal a molecular basis for an activating protein 2-dependent dysregulation of manganese superoxide dismutase expression in cancer cells. MnSOD, Sp1
33  2008 PKC-dependent stimulation of the human MCT1 promoter involves transcription factor AP2. SCFA
34  2008 SCCRO (DCUN1D1) induces extracellular matrix invasion by activating matrix metalloproteinase 2. MMP-2
35  2008 The combined immunodetection of AP-2alpha and YY1 transcription factors is associated with ERBB2 gene overexpression in primary breast tumors. siRNA, YY1
36  2008 The insulin receptor: a new anticancer target for peroxisome proliferator-activated receptor-gamma (PPARgamma) and thiazolidinedione-PPARgamma agonists. IR, PPARgamma, TZDs
37  2007 Activator protein-2 in carcinogenesis with a special reference to breast cancer--a mini review. ER, HER2
38  2007 Analysis of specific transcriptional regulators as early predictors of independent prognostic relevance in resected colorectal cancer. ---
39  2007 AP-2 regulates the transcription of estrogen receptor (ER)-beta by acting through a methylation hotspot of the 0N promoter in prostate cancer cells. ER, PCa
40  2007 Cloning, characterization and computational analysis of the 5' regulatory region of ovine glucose 6-phosphate dehydrogenase gene. G6PD, GATA, HNF-4, HSF, MEP, RAR, RFX, Sp1, SREBP, STRE, USF
41  2007 Loss of AP-2alpha results in deregulation of E-cadherin and MMP-9 and an increase in tumorigenicity of colon cancer cells in vivo. MMP-9
42  2007 Rad51 overexpression contributes to chemoresistance in human soft tissue sarcoma cells: a role for p53/activator protein 2 transcriptional regulation. STS, wtp53
43  2007 Salbutamol increases tristetraprolin expression in macrophages. 3'-UTR, AREs, GM-CSF, IBMX, NF-kappaB, PDEs, TNF-alpha, TTP
44  2007 Transcriptional regulation of the cholesterol side chain cleavage cytochrome P450 gene (CYP11A1) revisited: binding of GATA, cyclic adenosine 3',5'-monophosphate response element-binding protein and activating protein (AP)-1 proteins to a distal novel cluster of cis-regulatory elements potentiates AP-2 and steroidogenic factor-1-dependent gene expression in the rodent placenta and ovary. AP, CRE
45  2006 A polymorphism in the EAAT2 promoter is associated with higher glutamate concentrations and higher frequency of progressing stroke. GCF2
46  2006 Activator protein-2 overexpression accounts for increased insulin receptor expression in human breast cancer. HMGA1, IR
47  2006 Analysis of transcription factor AP-2 expression and function during mouse preimplantation development. ---
48  2006 Dopamine D3 receptors regulate GABAA receptor function through a phospho-dependent endocytosis mechanism in nucleus accumbens. GABAAR, NAc, PKA
49  2006 NF-Y, AP2, Nrf1 and Sp1 regulate the fragile X-related gene 2 (FXR2). FMRP, FXR1P, FXR2
50  2006 Pathophysiologic and therapeutic implications of adrenomedullin in cardiovascular disorders. AM, NF-IL6
51  2006 Regulation of the human biotin transporter hSMVT promoter by KLF-4 and AP-2: confirmation of promoter activity in vivo. hSMVT, KLF4
52  2005 Activation of the insulin-like growth factor binding protein-5 promoter by parathyroid hormone in osteosarcoma cells requires activation of an activated protein-2 element. C/EBP, IGFBP-5, NF1, PTH
53  2005 Decrease in the AP-2 DNA-binding activity and in the protein expression of AP-2 alpha and AP-2 beta in frontal cortex of rats treated with lithium for 6 weeks. AA, AP-1, cPLA2, LiCl, PKC
54  2005 Gene regulation and physiological function of placental leucine aminopeptidase/oxytocinase during pregnancy. OT, OTase, P-LAP
55  2005 No apparent association between genetic polymorphisms (-102 C>T) and (-9 T>C) in the human manganese superoxide dismutase gene and gastric cancer(1). CI, MnSOD, OR
56  2005 Role of mitogen-activated protein kinase pathway in reactive oxygen species-mediated endothelin-1-induced beta-myosin heavy chain gene expression and cardiomyocyte hypertrophy. beta-MyHC, ET-1, MAPKs, ROS, Sp1
57  2005 Ultraviolet A-induced signaling involves a ceramide-mediated autocrine loop leading to ceramide de novo synthesis. ICAM-1, UVA
58  2005 Yin Yang 1 cooperates with activator protein 2 to stimulate ERBB2 gene expression in mammary cancer cells. YY1
59  2005 [AP-2 expression and significance in the lung cancer tissues]. NSCLC
60  2004 Differential expression of activator protein-2 isoforms in renal cell carcinoma. RCC
61  2004 Expression of HER2 and its association with AP-2 in breast cancer. BCRS, CISH, HER2, IHC, RFS
62  2004 Involvement of AP-2 binding sites in regulation of human beta-glucuronidase. ---
63  2004 Method for determination of (-102C>T) single nucleotide polymorphism in the human manganese superoxide dismutase promoter. MnSOD
64  2004 Regulation of sphingosine kinase 1 gene expression by protein kinase C in a human leukemia cell line, MEG-O1. EMSA, PKC, PMA, Sp1, SphK
65  2004 Requirement for proximal putative Sp1 and AP-2 cis-deoxyribonucleic acid elements in mediating basal and luteinizing hormone- and insulin-dependent in vitro transcriptional activation of the CYP17 gene in porcine theca cells. CYP17, Sp1
66  2004 Transcriptional regulation of the human chorionic gonadotropin beta gene during villous trophoblast differentiation. Sp
67  2004 YY1 is involved in RANKL-induced transcription of the tartrate-resistant acid phosphatase gene in osteoclast differentiation. NF-kappaB, TRAP, USF, YY1
68  2003 Activator protein-2gamma (AP-2gamma) expression is specifically induced by oestrogens through binding of the oestrogen receptor to a canonical element within the 5'-untranslated region. 5'-UTR, AP-2gamma, ERalpha
69  2003 AP-2 and HNK-1 define distinct populations of cranial neural crest cells. CNCC
70  2003 Associations of a polymorphic AP-2 binding site in the 5'-flanking region of the bovine beta-lactoglobulin gene with milk proteins. beta-LG, HF, SM, SNP
71  2003 Binding of AP-2 and ETS-domain family members is associated with enhancer activity in the hypersensitive site III region of the human growth hormone/chorionic somatomammotropin locus. AP
72  2003 Characterization of the human activator protein-2gamma (AP-2gamma) gene: control of expression by Sp1/Sp3 in breast tumour cells. AP-2gamma
73  2003 Cloning and characterization of porcine common gamma chain gene. IL-2R, NK, RH, TCF-1
74  2003 Functional characterization of the interacting domains of the positive coactivator PC4 with the transcription factor AP-2alpha. AD, PC4, PC4, ss
75  2003 GCF2: expression and molecular analysis of repression. EGFR, FISH, GCF2
76  2003 Kinetics of lipopolysaccharide-induced transcription factor activation/inactivation and relation to proinflammatory gene expression in the murine spleen. AP-1, C/EBP, CRE, EMSA, IL, LPS, NF-kappaB, Sp1, TNF-alpha
77  2003 Mitochondrial cytochrome c release mediates ceramide-induced activator protein 2 activation and gene expression in keratinocytes. cyt c, ICAM-1
78  2003 p21WAF1 expression in invasive breast cancer and its association with p53, AP-2, cell proliferation, and prognosis. BCRS, PR, RFS
79  2003 Phenelzine treatment increases transcription factor AP-2 levels in rat brain. MAO, NA, PLZ, TCA
80  2003 Placental leucine aminopeptidase/oxytocinase gene regulation by activator protein-2 in BeWo cell model of human trophoblast differentiation. FSK, P-LAP
81  2003 Positive influence of AP-2alpha transcription factor on cadherin gene expression and differentiation of the ocular surface. ---
82  2003 Variations of human adrenomedullin gene and its relation to cardiovascular diseases. AM, CA, HIF-1, NF-IL6
83  2003 [The study on the interleukin-8 (IL-8)]. AP-1, HNF1, IL-8, IL-8R, IRF-1
84  2002 Chronic citalopram treatment induces time-dependent changes in the expression and DNA-binding activity of transcription factor AP-2 in rat brain. ---
85  2002 Combinatorial interactions of p53, activating protein-2, and YB-1 with a single enhancer element regulate gelatinase A expression in neoplastic cells. ---
86  2002 Essential role of an activator protein-2 (AP-2)/specificity protein 1 (Sp1) cluster in the UVB-mediated induction of the human vascular endothelial growth factor in HaCaT keratinocytes. Sp1, VEGF
87  2002 Identification of HTF (HER2 transcription factor) as an AP-2 (activator protein-2) transcription factor and contribution of the HTF binding site to ERBB2 gene overexpression. ---
88  2002 Induction of cyclooxygenase-2 by staurosporine through the activation of nuclear factor for IL-6 (NF-IL6) and activator protein 2 (AP2) in an osteoblast-like cell line. COX-2, NF-IL6
89  2002 Modulation of the human protein kinase C alpha gene promoter by activator protein-2. GBM, PKCalpha
90  2002 No association between a transcription factor Activating Protein 2beta (AP-2beta) gene variant and schizophrenia. AP-2beta
91  2002 Penta-O-galloyl-beta-D-glucose inhibits the invasion of mouse melanoma by suppressing metalloproteinase-9 through down-regulation of activator protein-1. AP-1, EMSA, MMP, NF-kappaB, PEA-3, RT-PCR
92  2002 Reduced nuclear expression of transcription factor AP-2 associates with aggressive breast cancer. BCRS, RFS
93  2002 Structural and functional characterization of the human and mouse fibulin-1 gene promoters: role of Sp1 and Sp3. ---
94  2002 Transcriptional regulation of the human manganese superoxide dismutase gene: the role of specificity protein 1 (Sp1) and activating protein-2 (AP-2). AP, MnSOD, Sp1
95  2001 Cloning and functional analysis of SEL1L promoter region, a pancreas-specific gene. ---
96  2001 Constitutive activation of transcription factor AP-2 is associated with decreased MnSOD expression in transformed human lung fibroblasts. MnSOD, SOD2
97  2001 Estradiol upregulates mesangial cell MMP-2 activity via the transcription factor AP-2. ERK/MAPK, MMP-2
98  2001 Functional characterization of the basal promoter of the murine LH receptor gene in immortalized mouse Leydig tumor cells. bp, LHR
99  2001 Induction of transcription factor AP-2 by cytokines and prostaglandins in cultured mesangial cells. ---
100  2001 Lipopolysaccharide regulates constitutive and inducible transcription factor activities differentially in vivo in the rat. AP-1, CREB