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Abbreviation : APDC
Long Form : 4-aminopyrrolidine-2,4-dicarboxylate
No. Year Title Co-occurring Abbreviation
2016 Group II mGluRs suppress hyperexcitability in mouse and human nociceptors. DRG, PGE2
2013 Catalytic asymmetric construction of quaternary alpha-amino acid containing pyrrolidines through 1,3-dipolar cycloaddition of azomethine ylides to alpha-aminoacrylates. FOXAP
2010 Ameliorative effect of a hippocampal metabotropic glutamate- receptor agonist on histamine H1 receptor antagonist-induced memory deficit in rats. DHPG, L-AP4, mGlu
2010 Metabotropic glutamate receptors (mGluRs) regulate noxious stimulus-induced glutamate release in the spinal cord dorsal horn of rats with neuropathic and inflammatory pain. CCI, CFA, CPCCOEt, l-AP4, mGluR, mGluRs, MPEP
2010 [Group II metabotropic glutamate receptors is involved in the modulation of respiratory rhythmical discharge activity in neonatal rat medullary brain slices]. MKS, mNRF, RRDA
2009 Distinct roles of metabotropic glutamate receptor activation on inhibitory signaling in the ventral lateral geniculate nucleus. ACPD, DHPG, mGluR, sIPSC, TTX, vLGN
2009 Effects of repeated exposure to cocaine on group II metabotropic glutamate receptor function in the rat medial prefrontal cortex: behavioral and neurochemical studies. mGluR, mPFC
2008 Group II metabotropic glutamate receptor activation attenuates peripheral sensitization in inflammatory states. mGluR
2008 Strain differences in alcohol-induced neurochemical plasticity: a role for accumbens glutamate in alcohol intake. GABA, NAc, TBOA
10  2007 Intrathecal injection of glutamate receptor antagonists/agonist selectively attenuated rat pain-related behaviors induced by the venom of scorpion Buthus martensi Karsch. BmK, CNQX
11  2007 Involvement of group II metabotropic glutamate receptors in stress-induced behavioural sensitization. mGluR
12  2006 Metabotropic glutamate receptors differentially regulate GABAergic inhibition in thalamus. DHPG, dLGN, mGluRs, MPEP, sIPSCs, TRN
13  2006 Participation of peripheral group I and II metabotropic glutamate receptors in the development or maintenance of IL-1beta-induced mechanical allodynia in the orofacial area of conscious rats. CPCCOEt, IL, mGluRs, MPEP
14  2005 beta-Amyloid peptides impair PKC-dependent functions of metabotropic glutamate receptors in prefrontal cortical neurons. AD, DHPG, mGluRs, NMDA, NMDAR, PKC, sIPSC
15  2005 Group I and II metabotropic glutamate receptors alter brain cortical metabolic and glutamate/glutamine cycle activity: a 13C NMR spectroscopy and metabolomic study. CHPG, DHPG, mGluR
16  2004 Interactions of carbon monoxide and metabotropic glutamate receptor groups in the nucleus tractus solitarii of rats. DHPG, l-AP4
17  2004 Peripheral glutamate receptors contribute to mechanical hyperalgesia in a neuropathic pain model of the rat. DL-AP3, Glu, L5 DR, L5 SNL, mGlu, NBQX, NMDA, PWT
18  2003 Enhancement of low-voltage-activated calcium currents by group II metabotropic glutamate receptors in rat retinal ganglion cells. LVA, mGluR
19  2002 Different metabotropic glutamate receptors play opposite roles in synaptic plasticity of the rat medial vestibular nuclei. CHPG, DHPG, HFS, L-AP4, LTP, mGluRs, MPEP, MSOP, MSPG, MVN, PPF
20  2002 Group II metabotropic glutamate receptors modulate extracellular glutamate in the nucleus accumbens. PKA
21  2002 Modulation of group II metabotropic glutamate receptor signaling by chronic cocaine. PFC
22  2002 Peripheral group II metabotropic glutamate receptors (mGluR2/3) regulate prostaglandin E2-mediated sensitization of capsaicin responses and thermal nociception. mGluRs, PGE2
23  2002 Variation of CS salience reveals group II mGluR-dependent and -independent forms of conditioning in the rat. i.p, mGluRs
24  2000 2R,4R-4-Aminopyrrolidine-2,4-dicarboxylate (APDC) attenuates cortical EPSPs. ---
25  1999 Type I and II metabotropic glutamate receptors mediate depressor and bradycardic actions in the nucleus of the solitary tract of anaesthetized rats. DHPG, mGlu, RS
26  1997 Modulation of excitatory synaptic transmission in locus coeruleus by multiple presynaptic metabotropic glutamate receptors. 4C-3H-PG, AIDA, DHPG, L-AP4, MAP4, RS
27  1996 Synthesis of the four isomers of 4-aminopyrrolidine-2,4-dicarboxylate: identification of a potent, highly selective, and systemically-active agonist for metabotropic glutamate receptors negatively coupled to adenylate cyclase. mGluRs