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Abbreviation : AQP5
Long Form : aquaporin 5
No. Year Title Co-occurring Abbreviation
2019 Aquaporin 5 -1364A/C Promoter Polymorphism Is Associated with Pulmonary Inflammation and Survival in Acute Respiratory Distress Syndrome. ---
2019 Blockade of CD40-CD154 pathway interactions suppresses ectopic lymphoid structures and inhibits pathology in the NOD/ShiLtJ mouse model of Sjogren's syndrome. SGs, SS
2019 Effect of low temperature on the regulation of cell volume after hypotonic shock in gastric cancer cells. GC, RVD
2019 MicroRNA-325-3p inhibits cell proliferation and induces apoptosis in hepatitis B virus-related hepatocellular carcinoma by down-regulation of aquaporin 5. HBV, HCC, miRNAs, siRNA
2019 MIST1, an Inductive Signal for Salivary Amylase in Mesenchymal Stem Cells. AMY1, CK19, M3R, MET, MIST1, MSC, SjS, TFs
2019 Ovatodiolide suppresses inflammatory response in BEAS-2B cells by regulating the CREB/AQP5 pathway, and sensitizes nasopharyngeal carcinoma cells to radiation therapy. NPC, Ova
2019 Parasympathectomy increases resting secretion of the submandibular gland in minipigs in the long term. mAChR, SMG
2019 Potential forensic application of receptor for advanced glycation end products (RAGE) and aquaporin 5 (AQP5) as novel biomarkers for diagnosis of drowning. IL-1beta, IL-6, RAGE, SP-A
2019 Quantitative screening of the effects of hyper-osmotic stress on cancer cells cultured in 2- or 3-dimensional settings. ---
10  2019 Submandibular gland-specific inflammaging-induced hyposalivation in the male senescence-accelerated mouse prone -1line (SAM-P1). PG, SAM-P1, SMG
11  2019 Targeted TNF-alpha Overexpression Drives Salivary Gland Inflammation. ---
12  2019 Urinary AQP5 is independently associated with eGFR decline in patients with type 2 diabetes and nephropathy. eGFR
13  2019 Wnt signaling regulates trans-differentiation of stem cell like type 2 alveolar epithelial cells to type 1 epithelial cells. ANN, EMP2, ITGAV, TD, THBS1
14  2019 [Role and mechanism of muscarinic acetylcholine receptor in the regulation of submandibular gland secretion]. F-actin, mAChRs, SMG
15  2018 Anti-cancer effect of Aquaporin 5 silencing in colorectal cancer cells in association with inhibition of Wnt/beta-catenin pathway. EMT, MMP, TIMP, uPA
16  2018 Aquaporin 5 is degraded by autophagy in diabetic submandibular gland. HG
17  2018 Aquaporine-5 and epithelial sodium channel beta-subunit gene expression in gastric aspirates in human term newborns. betaENaC, GA
18  2018 Dexamethasone attenuates methacholine-mediated aquaporin 5 downregulation in human nasal epithelial cells via suppression of NF-kappaB activation. HNEpC, NF-kappaB
19  2018 Distribution of aquaporin-5, transforming growth factor-beta1 and laminin during regeneration of atrophic rat submandibular glands after duct ligation. DLSs, ICDs, TGF-beta1
20  2018 Ectopic expression of aquaporin-5 in noncancerous epithelial MDCK cells changes cellular morphology and actin fiber formation without inducing epithelial-to-mesenchymal transition. ---
21  2018 Effects of standardized isopropanolic black cohosh and estrogen on salivary function in ovariectomized rats. ---
22  2018 Evaluation of Anticancer Activity of Camellia Sinensis in the Caco-2 Colorectal Cancer Cell Line CRC
23  2018 Glycyrrhizin attenuates histamine-mediated MUC5AC upregulation, inflammatory cytokine production, and aquaporin 5 downregulation through suppressing the NF-kappaB pathway in human nasal epithelial cells. AR, HNEpCs, IL, MUC5AC, pCREB
24  2018 Ixeris dentata Extract Increases Salivary Secretion through the Regulation of Endoplasmic Reticulum Stress in a Diabetes-Induced Xerostomia Rat Model. DM, IXD
25  2018 Knockdown of aquaporin-5 sensitizes colorectal cancer cells to 5-fluorouracil via inhibition of the Wnt-beta-catenin signaling pathway. 5-FU, CRC
26  2018 Low-level laser therapy with 850 nm recovers salivary function via membrane redistribution of aquaporin 5 by reducing intracellular Ca2+ overload and ER stress during hyperglycemia. LLLT, STZ
27  2018 Mesenchymal stem cells overexpressing Ang1 attenuates phosgene-induced acute lung injury in rats. Ang-1, BALF, MSCs, P-ALI, SP-C
28  2018 Postnatal changes in the development of rat submandibular glands in offspring of diabetic mothers: Biochemical, histological and ultrastructural study. Bax, Bcl-2, CK5, EGF, PAS, PCNA, STZ
29  2018 Procaine stimulates aquaporin‑5 expression in human salivary gland ductal cells via the suppression of DNA methyltransferase‑1. DNMT
30  2018 Saquinavir plus methylprednisolone ameliorates experimental acute lung injury. ALI, GRalpha, HMGB1, HPMECs, LPS, MPO, MPS, pNF-kappaB, SQV, TLR4
31  2018 Silencing of aquaporin5 inhibits the growth of A549 lung cancer cells in vitro and in vivo. ---
32  2018 The aquaporin 5 -1364A/C promoter polymorphism impacts on resolution of acute kidney injury in pneumonia evoked ARDS. AKI
33  2018 [Comparison of the secretory related molecules expression in stem cells from the pulp of human exfoliated deciduous teeth and dental pulp stem cells]. beta1-AR, CCK-8, DPSC, MR1, qPCR, SHED
34  2018 [Novel tear secretion system - the effect and the mechanism of PACAP on tear secretion]. PACAP
35  2017 A novel organotypic 3D sweat gland model with physiological functionality. NKCC1
36  2017 AQP5 promotes hepatocellular carcinoma metastasis via NF-kappaB-regulated epithelial-mesenchymal transition. EMT, HCC
37  2017 Association of Gel-Forming Mucins and Aquaporin Gene Expression With Hearing Loss, Effusion Viscosity, and Inflammation in Otitis Media With Effusion. MUC2, MUC5AC, MUC5B, OM, OME
38  2017 Cellular distribution and function of ion channels involved in transport processes in rat tracheal epithelium. ANO1, CFTR
39  2017 Chlorpheniramine attenuates histamine-mediated aquaporin 5 downregulation in human nasal epithelial cells via suppression of NF-kappaB activation. HNEpC
40  2017 Differential expression of aquaporin-3 and aquaporin-5 in pancreatic ductal adenocarcinoma. PDA
41  2017 Down-regulation of aquaporin 5-mediated epithelial-mesenchymal transition and anti-metastatic effect by natural product Cairicoside E in colorectal cancer. CE, CRC, EMT
42  2017 Effects of AQP5 gene silencing on proliferation, migration and apoptosis of human glioma cells through regulating EGFR/ERK/ p38 MAPK signaling pathway. FCM
43  2017 Heat shock exerts anticancer effects on liver cancer via autophagic degradation of aquaporin 5. BafA1, CHX, IF, LC3B, WB
44  2017 Hyperosmolarity-induced AQP5 upregulation promotes inflammation and cell death via JNK1/2 Activation in human corneal epithelial cells. DED, HCECs
45  2017 Immunohistochemical evalulation of activated Ras and Rac1 as potential downstream effectors of aquaporin-5 in breast cancer invivo. ---
46  2017 Involvement of water channel Aquaporin 5 in H2S-induced pulmonary edema. ---
47  2017 Runx1 mediates the development of the granular convoluted tubules in the submandibular glands. CBFbeta, cKO, GCTs, SMG
48  2017 Temporal Expression Patterns of Clock Genes and Aquaporin 5/Anoctamin 1 in Rat Submandibular Gland Cells. SCN, SGs
49  2017 The effect of meconium exposure on the expression and differentiation of amniotic fluid mesenchymal stem cells. AF medium, AF-MSCs, mSAGM, SP-C
50  2017 Vasoactive Intestinal Peptide Protects Salivary Glands against Structural Injury and Secretory Dysfunction via IL-17A and AQP5 Regulation in a Model of Sjogren Syndrome. SS, VIP
51  2017 [Effects of the fermentation products of endophytes from Glycyrrhiza uralensis on inflammation-associated factors and Aquaporin in rat models with phlegm blocking in lung]. AQP1, COX-2, ICAM-1, NO
52  2017 [Role of aquaporin-5 in regulating colorectal cancer cell growth in vitro]. siRNA
53  2016 ALX/FPR2 Modulates Anti-Inflammatory Responses in Mouse Submandibular Gland. LPS, RvD1, SMG
54  2016 An Experimental Study on Botulinum Toxin Type A for the Treatment of Excessive Secretion after Submandibular Gland Transplantation in Rabbits. BTX-A, HE, SMG, TEM
55  2016 Aquaporin 5 expression is frequent in prostate cancer and shows a dichotomous correlation with tumor phenotype and PSA recurrence. PTEN
56  2016 Aquaporin-5: from structure to function and dysfunction in cancer. ---
57  2016 Combinations of differentiation markers distinguish subpopulations of alveolar epithelial cells in adult lung. AEC, HOPX
58  2016 Cyclic adenosine monophosphate-protein kinase A signal pathway may be involved in pulmonary aquaporin-5 expression in ischemia/reperfusion rats following deep hypothermia cardiac arrest. cAMP-PKA, I/R
59  2016 Investigation of age-related changes in the expression of aquaporin-1 and aquaporin-5 in the salivary glands of mice. AQP1
60  2016 Mechanisms Underlying Activation of alpha₁-Adrenergic Receptor-Induced Trafficking of AQP5 in Rat Parotid Acinar Cells under Isotonic or Hypotonic Conditions. APM, AR, cGMP, GC, LPM, NO, PK
61  2016 New Findings on the Mechanism of Perspiration Including Aquaporin-5 Water Channel. ---
62  2016 Overexpression of AQP5 Was Detected in Axillary Sweat Glands of Primary Focal Hyperhidrosis Patients. PFH
63  2016 PACAP suppresses dry eye signs by stimulating tear secretion. PACAP
64  2016 Plasma level of soluble receptor for advanced glycation end-products and aquaporin 5 in preterm infants with acute respiratory distress syndrome. RDS, sRAGE
65  2016 Prognostic Significance of Aquaporin 5 Expression in Non-small Cell Lung Cancer. ADC, DFS, NSCLC, SqCC
66  2016 Rat Aquaporin-5 Is pH-Gated Induced by Phosphorylation and Is Implicated in Oxidative Stress. ---
67  2016 Store-operated Ca2+ entry regulates Ca2+-activated chloride channels and eccrine sweat gland function. ---
68  2016 The Transcription Factor NMP4 Binds to the AQP5 Promoter and Is a Novel Transcriptional Regulator of the AQP5 Gene. NMP4, SNP
69  2016 [Influence of hot-humid stress and acclimation on airway mucus production in lungs of mice]. MUC5AC
70  2015 Activation of muscarinic receptors in rat parotid acinar cells induces AQP5 trafficking to nuclei and apical plasma membrane. APM, LPM, mAChR
71  2015 Aquaporin 5 expression in mouse mammary gland cells is not driven by promoter methylation. DEX, nGREs
72  2015 Aquaporin 5 Plays a Role in Estrogen-Induced Ectopic Implantation of Endometrial Stromal Cells in Endometriosis. EMSA, ERE, ES, PI3K
73  2015 Dexmedetomidine alleviates pulmonary edema by upregulating AQP1 and AQP5 expression in rats with acute lung injury induced by lipopolysaccharide. AQP1, ELISA, IL-1beta, LPS, NS, TNF-alpha
74  2015 Differential Regulation of Gene Expression of Alveolar Epithelial Cell Markers in Human Lung Adenocarcinoma-Derived A549 Clones. 8-BrcAMP, ATII, DEX, IBMX, KGF, SP-C, TTF-1
75  2015 Effect of dobutamine on lung aquaporin 5 in endotoxine shock-induced acute lung injury rabbit. ALI, cAMP
76  2015 Effect of emodin on Aquaporin 5 expression in rats with sepsis-induced acute lung injury. ---
77  2015 Effect of keratinocyte growth factor on growth and transdifferentiation of primary alveolar epithelial type II cells. AECIIs, KGF, SP-C, TTF-1
78  2015 Effect of Phenylephrine Pretreatment on the Expressions of Aquaporin 5 and c-Jun N-Terminal Kinase in Irradiated Submandibular Gland. JNK
79  2015 Epigallocatechin gallate stimulates the neuroreactive salivary secretomotor system in autoimmune sialadenitis of MRL-Fas(lpr) mice via activation of cAMP-dependent protein kinase A and inactivation of nuclear factor kappaB. APMs, EGCG, HDAC1, IkappaB, JNK, NF-kappaB, PKA, ROS
80  2015 Evaluation of the effects of quercetin on damaged salivary secretion. HSY, MAECs
81  2015 Expression of aquaporin-1, aquaporin-3, and aquaporin-5 correlates with nodal metastasis in colon cancer. AQP1, AQP3
82  2015 Expression of aquaporin5 in primary carcinoma and lymph node metastatic carcinoma of non-small cell lung cancer. NSCLC
83  2015 Histamine downregulates aquaporin 5 in human nasal epithelial cells. CREB, HNEpC, mRNA
84  2015 Low-intensity pulsed ultrasound rescues insufficient salivary secretion in autoimmune sialadenitis. LIPUS, NF-kappaB, SS
85  2015 Modulation by thyroid hormone of myosin light chain phosphorylation and aquaporin 5 protein expression in intact lung. HO, HR, MLCK, THs
86  2015 Opposing Effects of cAMP and T259 Phosphorylation on Plasma Membrane Diffusion of the Water Channel Aquaporin-5 in Madin-Darby Canine Kidney Cells. PKA
87  2015 Plasma Membrane Abundance of Human Aquaporin 5 Is Dynamically Regulated by Multiple Pathways. ---
88  2015 Pre- and Post-synaptic Effects of Botulinum Toxin A on Submandibular Glands. SMG, SNAP-25
89  2015 Retinoic acid promotes primary fetal alveolar epithelial type II cell proliferation and differentiation to alveolar epithelial type I cells. AECIs, fAECIIs, RA
90  2015 The role of dexamethasone in scorpion venom-induced deregulation of sodium and water transport in rat lungs. IL, TLR4
91  2015 [Activation of transient receptor potential vanilloid subtype 1 serves as a novel pathway to modulate secretion in submandibular gland]. MLC2, RT-PCR, TRPV1
92  2015 [AQP5 gene silencing inhibits proliferation and migration of ectopic endometrial glandular epithelial cells in endometriosis]. p-AKT
93  2015 [The changes of Wnt7b/beta-catenin signaling pathway molecules in the differentiation of fetal alveolar epithelial type II cells]. ---
94  2014 AQP5 expression predicts survival in patients with early breast cancer. EBC, ER, HER2, PR
95  2014 AQP5 silencing suppresses p38 MAPK signaling and improves drug resistance in colon cancer cells. 5-FU, CC, ERK, GST-pi, JNK, MAPK, MDR, P-gp, SRB, topo II, TS
96  2014 Aquaporin 5 expression is altered in ovarian tumors and ascites-derived ovarian tumor cells in the chicken model of ovarian tumor. COVCAR, ir, NOSE
97  2014 Aquaporin 5 increases keratinocyte-derived chemokine expression and NF-kappaB activity through ERK activation. KC
98  2014 Biocompatible tissue scaffold compliance promotes salivary gland morphogenesis and differentiation. SM alpha-actin
99  2014 Characterization of the effects of the vasopressin V2 receptor on sweating, fluid balance, and performance during exercise. AVP, V2R
100  2014 Correlation of apical fluid-regulating channel proteins with lung function in human COPD lungs. ATI, CFTR, COPD, ENaC