1 |
2020 |
Acid exposure disrupts mucus secretion and impairs mucociliary transport in neonatal piglet airways. |
CF, MUC5B |
2 |
2020 |
Acid-sensing ion channel 3 blockade inhibits durovascular and nitric oxide-mediated trigeminal pain. |
--- |
3 |
2020 |
Epigenetic upregulation of acid-sensing ion channel 1 contributes to gastric hypersensitivity in adult offspring rats with prenatal maternal stress. |
DRG, GHS, NF-kappaB, PMS |
4 |
2020 |
Heterologous expression of biologically active Mambalgin-1 peptide as a new potential anticancer, using a PVX-based viral vector in Nicotiana benthamiana. |
PVX |
5 |
2020 |
Histidine Residues Are Responsible for Bidirectional Effects of Zinc on Acid-Sensing Ion Channel 1a/3 Heteromeric Channels. |
--- |
6 |
2020 |
Insights into the molecular mechanisms underlying the inhibition of acid-sensing ion channel 3 gating by stomatin. |
STOM |
7 |
2020 |
Machaerium hirtum (Vell.) Stellfeld Alleviates Acute Pain and Inflammation: Potential Mechanisms of Action. |
HEMh, PGE2 |
8 |
2020 |
Stability of extemporaneously compounded amiloride nasal spray. |
AD, HPLC, USP |
9 |
2019 |
Amiloride does not protect retinal nerve fibre layer thickness in optic neuritis in a phase 2 randomised controlled trial. |
ITT, MS, OCT, ON, VEP |
10 |
2019 |
Chondroitin sulfate attenuates acid-induced augmentation of the mechanical response in rat thin-fiber muscle afferents in vitro. |
CS, EPR, TRPV1 |
11 |
2019 |
Endogenous Neuropeptide Nocistatin Is a Direct Agonist of Acid-Sensing Ion Channels (ASIC1, ASIC2 and ASIC3). |
--- |
12 |
2019 |
Inhibition on acid-sensing ion channels and analgesic activities of flavonoids isolated from dragon's blood resin. |
CFA, DRG |
13 |
2019 |
Inhibitory ASIC2-mediated calcineurin/NFAT against colorectal cancer by triterpenoids extracted from Rhus chinensis Mill. |
CRC, NFAT, TER |
14 |
2019 |
Involvement of the epithelial sodium channel in initiation of mechanically evoked swallows in anaesthetized rats. |
ENaC |
15 |
2019 |
Ion Channel Pharmacology for Pain Modulation. |
TRP, VGCC |
16 |
2019 |
Multiple modes of action of hydrophobic amines and their guanidine analogues on ASIC1a. |
CHO |
17 |
2019 |
Opioid-Mediated Modulation of Acid-Sensing Ion Channel Currents in Adult Rat Sensory Neurons. |
DRG, PAD |
18 |
2019 |
Sa12b Peptide from Solitary Wasp Inhibits ASIC Currents in Rat Dorsal Root Ganglion Neurons. |
DRG |
19 |
2019 |
The antitrypanosomal diarylamidines, diminazene and pentamidine, show anthelmintic activity against Haemonchus contortus in vitro. |
--- |
20 |
2019 |
Thin-fibre receptors expressing acid-sensing ion channel 3 contribute to muscular mechanical hypersensitivity after exercise. |
2.2muM, DOMS, LC |
21 |
2019 |
[New horizons for acute and prophylactic treatments of migraine]. |
CGRP, NPY, PACAP |
22 |
2018 |
Acid Sensing Ion Channel 1a (ASIC1a) Mediates Activity-induced Pain by Modulation of Heteromeric ASIC Channel Kinetics. |
ASIC1a |
23 |
2018 |
Dual role of acid-sensing ion channels 3 in rheumatoid arthritis: destruction or protection? |
--- |
24 |
2018 |
Effects of creatine supplementation on nociception in young male and female mice. |
--- |
25 |
2018 |
Neuroprotective Effects of Psalmotoxin-1, an Acid-Sensing Ion Channel (ASIC) Inhibitor, in Ischemia Reperfusion in Mouse Eyes. |
GPX4, HSP70, PERG, RBPMS, RGCs, SOD1 |
26 |
2018 |
PhcrTx2, a New Crab-Paralyzing Peptide Toxin from the Sea Anemone Phymanthus crucifer. |
DRG |
27 |
2018 |
Protons as Messengers of Intercellular Communication in the Nervous System. |
CNS |
28 |
2017 |
Acid-sensing ion channel (ASIC) structure and function: Insights from spider, snake and sea anemone venoms. |
ASICs |
29 |
2017 |
Acidity and Acid-Sensing Ion Channels in the Normal and Alzheimer's Disease Brain. |
--- |
30 |
2017 |
Biological Behavior of Human Nucleus Pulposus Mesenchymal Stem Cells in Response to Changes in the Acidic Environment During Intervertebral Disc Degeneration. |
IVDD, NPMSCs |
31 |
2017 |
Endomorphins potentiate acid-sensing ion channel currents and enhance the lactic acid-mediated increase in arterial blood pressure: effects amplified in hindlimb ischaemia. |
ASICs, DRG, MOR, PAD |
32 |
2017 |
Enhanced maximal exercise capacity, vasodilation to electrical muscle contraction, and hind limb vascular density in ASIC1a null mice. |
FVC |
33 |
2017 |
Involvement of Opioid System, TRPM8, and ASIC Receptors in Antinociceptive Effect of Arrabidaea brachypoda (DC) Bureau. |
DEAB, TRPA1, TRPM8, TRPV1 |
34 |
2017 |
Modulation of the FMRFamide-gated Na+ channel by external Ca2. |
FaNaC |
35 |
2017 |
Proton and non-proton activation of ASIC channels. |
--- |
36 |
2017 |
The acid-sensing ion channel, ASIC2, promotes invasion and metastasis of colorectal cancer under acidosis by activating the calcineurin/NFAT1 axis. |
CRC, CsA |
37 |
2016 |
Acid-sensing ion channel 3 or P2X2/3 is involved in the pain-like behavior under a high bone turnover state in ovariectomized mice. |
TRPV1 |
38 |
2016 |
Acidic pH promotes intervertebral disc degeneration: Acid-sensing ion channel -3 as a potential therapeutic target. |
IVD |
39 |
2016 |
ASIC1a Deficient Mice Show Unaltered Neurodegeneration in the Subacute MPTP Model of Parkinson Disease. |
MPTP |
40 |
2016 |
Characterization of cutaneous and articular sensory neurons. |
HPD, TRPA1, TRPM8, TRPV1 |
41 |
2016 |
Combination of Ambiguous and Unambiguous Data in the Restraint-driven Docking of Flexible Peptides with HADDOCK: The Binding of the Spider Toxin PcTx1 to the Acid Sensing Ion Channel (ASIC) 1a. |
--- |
42 |
2016 |
Potential Roles of Amiloride-Sensitive Sodium Channels in Cancer Development. |
ENaC |
43 |
2016 |
Therapeutic Effect Analysis of Sinomenine on Rat Cerebral Ischemia-Reperfusion Injury. |
BBB, IR, LD, LDH, MCAO, NSS, SIN |
44 |
2016 |
TRPV1, ASICs and P2X2/3 expressed in bone cells simultaneously regulate bone metabolic markers in ovariectomized mice. |
--- |
45 |
2015 |
Acid-sensing ion channel (ASIC) 4 predominantly localizes to an early endosome-related organelle upon heterologous expression. |
ASICs |
46 |
2015 |
Acid-sensing ion channel 2 (ASIC2) is selectively localized in the cilia of the non-sensory olfactory epithelium of adult zebrafish. |
ASIC2 |
47 |
2015 |
Acid-sensing ion channels: a novel therapeutic target for pain and anxiety. |
--- |
48 |
2015 |
Genetic mapping of ASIC4 and contrasting phenotype to ASIC1a in modulating innate fear and anxiety. |
CNS, CR, NG2, VIP |
49 |
2015 |
Ionic homeostasis in brain conditioning. |
NHE |
50 |
2015 |
Mechanotransduction of trigeminal ganglion neurons innervating inner walls of rat anterior eye chambers. |
MS, TG, TRPA1, TRPV4 |
51 |
2015 |
Molecular dynamics and functional studies define a hot spot of crystal contacts essential for PcTx1 inhibition of acid-sensing ion channel 1a. |
cASIC1, MD |
52 |
2015 |
Peripheral and spinal mechanisms of nociception in a rat reserpine-induced pain model. |
DRG |
53 |
2015 |
Physical and functional interactions between a glioma cation channel and integrin-beta1 require alpha-actinin. |
ENaC |
54 |
2015 |
Sensory nerves contribute to cutaneous vasodilator response to cathodal stimulation in healthy rats. |
CGRP, CIV, NK-1, SP, TRPV1 |
55 |
2015 |
Tarantula toxins use common surfaces for interacting with Kv and ASIC ion channels. |
--- |
56 |
2014 |
A novel sea anemone peptide that inhibits acid-sensing ion channels. |
DRG, ICK |
57 |
2014 |
Acid-sensing ion channel (ASIC) 1a/2a heteromers have a flexible 2:1/1:2 stoichiometry. |
ASICs |
58 |
2014 |
Acid-sensing ion channels 1a (ASIC1a) inhibit neuromuscular transmission in female mice. |
ASIC1a, MNTs |
59 |
2014 |
Effects of acid on vagal nociceptive afferent subtypes in guinea pig esophagus. |
AP |
60 |
2014 |
Evidence for role of acid-sensing ion channels in nucleus ambiguus neurons: essential differences in anesthetized versus awake rats. |
--- |
61 |
2014 |
Subunit-specific inhibition of acid sensing ion channels by stomatin-like protein 1. |
DRG, STOML1 |
62 |
2014 |
The expression profile of acid-sensing ion channel (ASIC) subunits ASIC1a, ASIC1b, ASIC2a, ASIC2b, and ASIC3 in the esophageal vagal afferent nerve subtypes. |
ASICs |
63 |
2013 |
2-Guanidine-4-methylquinazoline acts as a novel competitive antagonist of A type gamma-aminobutyric acid receptors. |
fEPSPs, GABAARs, GMQ |
64 |
2013 |
A rapid facilitation of acid-sensing ion channels current by corticosterone in cultured hippocampal neurons. |
CORT, PKC |
65 |
2013 |
Coupling of proton binding in extracellular domain to channel gating in acid-sensing ion channel. |
DTT, ECD, MTSET, TCEP |
66 |
2013 |
Cyclophosphamide-induced cystitis reduces ASIC channel but enhances TRPV1 receptor function in rat bladder sensory neurons. |
CYP, DRG, TRPV1 |
67 |
2013 |
Mechanisms involved in the nociception triggered by the venom of the armed spider Phoneutria nigriventer. |
ArAv, PNV |
68 |
2012 |
ENaCs and ASICs as therapeutic targets. |
ENaC |
69 |
2012 |
Eosinophil peroxidase induces the expression and function of acid-sensing ion channel-3 in allergic rhinitis: in vitro evidence in cultured epithelial cells. |
AR, EPO |
70 |
2012 |
Ginsenoside-Rd attenuates TRPM7 and ASIC1a but promotes ASIC2a expression in rats after focal cerebral ischemia. |
GS, MCAO, NMDA, TRPM |
71 |
2012 |
Lignan from thyme possesses inhibitory effect on ASIC3 channel current. |
--- |
72 |
2012 |
Modulation of ionotropic glutamate receptors and Acid-sensing ion channels by nitric oxide. |
iGluR, NO |
73 |
2012 |
Molecules to selectively target receptors for treatment of pain and neurogenic inflammation. |
TRP |
74 |
2012 |
Muscle afferent receptors engaged in augmented sympathetic responsiveness in peripheral artery disease. |
BP, EPR, PAD, SNA, TRPV1 |
75 |
2012 |
Putative binding sites, and pathways to them, for amidine and guanidine current inhibitors on acid-sensing ion channels (ASIC). A theoretical approach with hASIC1a homology model. |
--- |
76 |
2012 |
Subtype-specific modulation of acid-sensing ion channel (ASIC) function by 2-guanidine-4-methylquinazoline. |
ASICs, GMQ |
77 |
2011 |
Blockade of acid sensing ion channels attenuates the augmented exercise pressor reflex in rats with chronic femoral artery occlusion. |
--- |
78 |
2011 |
Chronic hypoxia-induced acid-sensitive ion channel expression in chemoafferent neurons contributes to chemoreceptor hypersensitivity. |
CH, CSN, PG, SCG |
79 |
2011 |
Heteromeric acid-sensing ion channels (ASICs) composed of ASIC2b and ASIC1a display novel channel properties and contribute to acidosis-induced neuronal death. |
ASICs |
80 |
2011 |
Human odontoblasts express transient receptor protein and acid-sensing ion channel mechanosensor proteins. |
TRP |
81 |
2011 |
Interaction of ASIC1 and ENaC subunits in human glioma cells and rat astrocytes. |
Deg, ENaC, GBM, TIRFM, YFP |
82 |
2010 |
Acid-sensing ion channel (ASIC) 1a undergoes a height transition in response to acidification. |
--- |
83 |
2010 |
ASIC1a channels are activated by endogenous protons during ischemia and contribute to synergistic potentiation of intracellular Ca(2+) overload during ischemia and acidosis. |
--- |
84 |
2010 |
Demonstration of a direct interaction between sigma-1 receptors and acid-sensing ion channels. |
--- |
85 |
2010 |
Expression and response of acid-sensing ion channels in urinary bladder to cyclophosphamide-induced cystitis. |
CYP |
86 |
2010 |
Extracellular acidosis activates ASIC-like channels in freshly isolated cerebral artery smooth muscle cells. |
VSMCs |
87 |
2010 |
Increased response of muscle sensory neurons to decreases in pH after muscle inflammation. |
DiI, DRG |
88 |
2010 |
Regulation of acid signaling in rat pulmonary sensory neurons by protease-activated receptor-2. |
TRPV1 |
89 |
2010 |
Synthesis, structure-activity relationship, and pharmacological profile of analogs of the ASIC-3 inhibitor A-317567. |
SAR |
90 |
2009 |
Acid sensing ion channel (ASIC) inhibitors exhibit anxiolytic-like activity in preclinical pharmacological models. |
ASICs |
91 |
2009 |
Acid-evoked Ca2+ signalling in rat sensory neurones: effects of anoxia and aglycaemia. |
--- |
92 |
2009 |
Acid-sensing ion channel 3 expression in mouse knee joint afferents and effects of carrageenan-induced arthritis. |
CGRP, DRG |
93 |
2009 |
Acid-sensing ionic-channel functional expression in the vestibular endorgans. |
ASA |
94 |
2009 |
Amiloride inhibits hydrogen peroxide-induced Ca2+ responses in human CNS pericytes. |
NHE |
95 |
2009 |
ASIC1 contributes to pulmonary vascular smooth muscle store-operated Ca(2+) entry. |
VSM |
96 |
2009 |
Functional TRP and ASIC-like channels in cultured urothelial cells from the rat. |
TRP |
97 |
2009 |
Knockdown of ASIC1 and epithelial sodium channel subunits inhibits glioblastoma whole cell current and cell migration. |
ENaC |
98 |
2009 |
Mice lacking acid-sensing ion channels (ASIC) 1 or 2, but not ASIC3, show increased pain behaviour in the formalin test. |
ASICs, CFA |
99 |
2009 |
The ion channel ASIC2 is required for baroreceptor and autonomic control of the circulation. |
--- |
100 |
2009 |
[Expression of acid-sensing ion channels in neurons of trapezoid body and lateral paragigantocellular nuclei in rat brain, and effects of intermittent hypoxia on their expression]. |
IH |