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Abbreviation : Ad12
Long Form : adenovirus type 12
No. Year Title Co-occurring Abbreviation
2018 Inheritable epigenetic response towards foreign DNA entry by mammalian host cells: a guardian of genomic stability. EBV
2013 The N terminus of orf virus-encoded protein 002 inhibits acetylation of NF-kappaB p65 by preventing Ser(276) phosphorylation. E1A-12, EGFP, MSK1, ORFV002
2010 The N terminus of adenovirus type 12 E1A inhibits major histocompatibility complex class I expression by preventing phosphorylation of NF-kappaB p65 Ser276 through direct binding. E1A-12, E1A-5, MHC-I, PKAc
2009 Activation of the interferon-induced STAT pathway during an adenovirus type 12 infection. Ad2, ISGs
2009 Epigenetic mechanisms in human adenovirus type 12 oncogenesis. ---
2009 Induction of neuronal and tumor-related genes by adenovirus type 12 E1A. E1A-12
2008 Human CAR gene expression in nonpermissive hamster cells boosts entry of type 12 adenovirions and nuclear import of viral DNA. HCAR, p.i
2008 Tumorigenic adenovirus type 12 E1A inhibits phosphorylation of NF-kappaB by PKAc, causing loss of DNA binding and transactivation. E1A, E1A-12, MHC-I
2007 Epigenetic status of an adenovirus type 12 transgenome upon long-term cultivation in hamster cells. ---
10  2007 Human adenovirus type 12: crossing species barriers to immortalize the viral genome. ---
11  2005 Identification of specific cellular genes up-regulated late in adenovirus type 12 infection. ---
12  2004 Localization of integrated adenovirus DNA in the hamster genome. ---
13  2003 Differential expression of tapasin and immunoproteasome subunits in adenovirus type 5- versus type 12-transformed cells. Ad5, BRK, MHC
14  2003 Intraperitoneal dissemination of Ad12-induced undifferentiated neuroectodermal hamster tumors: de novo methylation and transcription patterns of integrated viral and of cellular genes. IM, PNET, s.c
15  2003 The abortive infection of Syrian hamster cells with human adenovirus type 12. MLP, pTP
16  2002 In adenovirus type 12 tumorigenic cells, major histocompatibility complex class I transcription shutoff is overcome by induction of NF-kappaB and relief of COUP-TFII repression. CTLs, IL-1beta, TNF-alpha
17  2002 Integrative recombination between adenovirus type 12 DNA and mammalian DNA in a cell-free system: joining by short sequence homologies. ---
18  2001 Binding of PKA-RIIalpha to the Adenovirus E1A12S oncoprotein correlates with its nuclear translocation and an increase in PKA-dependent promoter activity. CR1, PKA
19  2001 Cellular and early viral factors in the interaction of adenovirus type 12 with hamster cells: the abortive response. GFP
20  2001 Foreign DNA integration--perturbations of the genome--oncogenesis. GFP
21  2001 Foreign DNA integration. Genome-wide perturbations of methylation and transcription in the recipient genomes. MS-RDA
22  2001 Overexpression of the adenovirus type 12 (Ad12) pTP or E1A gene facilitates Ad12 DNA replication in nonpermissive BHK21 hamster cells. DBP, pol, pTP
23  2001 The fate of foreign DNA in mammalian cells and organisms. ---
24  2000 Association of histone deacetylase with COUP-TF in tumorigenic Ad12-transformed cells and its potential role in shut-off of MHC class I transcription. COUP-TF, MHC
25  2000 E1B 55-kilodalton oncoproteins of adenovirus types 5 and 12 inactivate and relocalize p53, but not p51 or p73, and cooperate with E4orf6 proteins to destabilize p53. Ad5
26  1999 Coxsackievirus and adenovirus receptor amino-terminal immunoglobulin V-related domain binds adenovirus type 2 and fiber knob from adenovirus type 12. Ad2, CAR, Ig
27  1999 Insertion of foreign DNA into an established mammalian genome can alter the methylation of cellular DNA sequences. IAP, IAPI
28  1999 Integrated viral genomes can be lost from adenovirus type 12-induced hamster tumor cells in a clone-specific, multistep process with retention of the oncogenic phenotype. PCR
29  1999 Reduced phosphorylation of p50 is responsible for diminished NF-kappaB binding to the major histocompatibility complex class I enhancer in adenovirus type 12-transformed cells. CTL
30  1999 Two domains within the adenovirus type 12 E1A unique spacer have disparate effects on the interaction of E1A with P105-Rb and the transformation of primary mouse cells. CR, E1Awt
31  1998 Adenovirus type 12-induced fragility of the human RNU2 locus requires p53 function. Rb, snRNA
32  1997 Adenovirus type 12 DNA firmly associates with mammalian chromosomes early after virus infection or after DNA transfer by the addition of DNA to the cell culture medium. FISH
33  1997 Clonal origin of adenovirus type 12-induced hamster tumors: nonspecific chromosomal integration sites of viral DNA. ---
34  1997 E1A 12S and 13S of the transformation-defective adenovirus type 12 strain CS-1 inactivate proteins of the RB family, permitting transactivation of the E2F-dependent promoter. E1A
35  1997 Identification of specific amino acid residues of adenovirus 12 E1A involved in transformation and p300 binding. E1A
36  1996 Chromosomal distribution of the hamster intracisternal A-particle (IAP) retrotransposons. CHO, FISH, IAP, LTR
37  1996 Early stage of human adenovirus type 12-inoculated retinal tissue of F344 newborn rat. PCNA, Rb, Rb gene
38  1996 Evidence for the involvement of a nuclear NF-kappa B inhibitor in global down-regulation of the major histocompatibility complex class I enhancer in adenovirus type 12-transformed cells. ---
39  1996 Insufficient levels of NFIII and its low affinity for the origin of adenovirus type 12 (Ad12) DNA replication contribute to the abortive infection of BHK21 hamster cells by Ad12. ori
40  1996 The structure of adenovirus type 12 DNA integration sites in the hamster cell genome. ---
41  1995 Adenovirus type 12-induced fragility of the human RNU2 locus requires U2 small nuclear RNA transcriptional regulatory elements. snRNA
42  1995 Altered phosphorylation and oligomerization of p53 in adenovirus type 12-transformed cells. ---
43  1995 Chromosomal insertion of foreign (adenovirus type 12, plasmid, or bacteriophage lambda) DNA is associated with enhanced methylation of cellular DNA segments. ---
44  1995 Distinct modulation of p53 activity in transcription and cell-cycle regulation by the large (54 kDa) and small (21 kDa) adenovirus E1B proteins. ---
45  1995 On the insertion of foreign DNA into mammalian genomes: mechanism and consequences. FISH
46  1995 Selective loss of unmethylated segments of integrated Ad12 genomes in revertants of the adenovirus type 12-transformed cell line T637. ---
47  1995 The initiation of de novo methylation of foreign DNA integrated into a mammalian genome is not exclusively targeted by nucleotide sequence. ---
48  1994 A multimegabase cluster of snRNA and tRNA genes on chromosome 1p36 harbours an adenovirus/SV40 hybrid virus integration site. PFGE, YACs
49  1994 Altered host range phenotype of the transformation-defective Ad12 mutant CS-1 is due to deletions in the E1 region. ---
50  1994 Antibody response to adenovirus E1b-derived synthetic peptides and serum levels of p53 in patients with gastrointestinal and other malignant lymphomas. ---
51  1994 E1A oncogene of adenovirus-12 mediates trans-repression of MHC class I transcription in Ad5/Ad12 somatic hybrid transformed cells. MHC
52  1994 Late transcripts of adenovirus type 12 DNA are not translated in hamster cells expressing the E1 region of adenovirus type 5. ---
53  1994 Negative regulation by the R2 element of the MHC class I enhancer in adenovirus-12 transformed cells correlates with high levels of COUP-TF binding. MHC
54  1994 Nucleotide sequence of human adenovirus type 12 DNA: comparative functional analysis. ---
55  1994 Selective sites of adenovirus (foreign) DNA integration into the hamster genome: changes in integration patterns. ---
56  1994 Vitronectin receptor antibodies inhibit infection of HeLa and A549 cells by adenovirus type 12 but not by adenovirus type 2. ---
57  1993 A unique mitigator sequence determines the species specificity of the major late promoter in adenovirus type 12 DNA. MLP
58  1993 Adenovirus 12 and dermatitis herpetiformis. CD, DH, GSE
59  1993 Antipeptide antibodies to adenovirus E1b protein indicate enhanced risk of celiac disease and dermatitis herpetiformis. CD, DH, ELISA
60  1993 Fractionated nuclear extracts from hamster cells catalyze cell-free recombination at selective sequences between adenovirus DNA and a hamster preinsertion site. ---
61  1993 Generation of a new adenovirus type 12-inducible fragile site by insertion of an artificial U2 locus in the human genome. ---
62  1993 Non-homologous recombination between adenovirus and AcNPV DNA fragments in cell-free extracts from insect Spodoptera frugiperda nuclei. AcNPV, PCR
63  1992 Acceleration of adenovirus replication and increased virion production by treatment with the steroid hormone 17 beta-estradiol. ---
64  1992 Alterations in the levels of expression of specific cellular genes in adenovirus-infected and -transformed cells. Ad2
65  1992 Chromosome alterations contribute to neoplastic progression of transformed rat embryonal fibroblasts. Ad5, HPV16 E7, REFs
66  1992 Down-regulation of the major histocompatibility complex class I enhancer in adenovirus type 12-transformed cells is accompanied by an increase in factor binding. ---
67  1992 Driving adenovirus type 12-transformed BALB/c mouse cells to express high levels of class I major histocompatibility complex proteins enhances, rather than abrogates, their tumorigenicity. MHC
68  1992 Highly efficient focus formation by Rous sarcoma virus on adenovirus type 12 E1A-transformed rat 3Y1 cells. RSV, RSV3Y1, RSVE1AY
69  1992 Negative regulation of the major histocompatibility complex class I enhancer in adenovirus type 12-transformed cells via a retinoic acid response element. RA
70  1992 Recombinant human adenoviruses containing hybrid adenovirus type 5 (Ad5)/Ad12 E1A genes: characterization of hybrid E1A proteins and analysis of transforming activity and host range. Ad5
71  1992 Recombination between adenovirus type 12 DNA and a hamster preinsertion sequence in a cell-free system. Patch homologies and fractionation of nuclear extracts. ---
72  1991 Spreading of DNA methylation across integrated foreign (adenovirus type 12) genomes in mammalian cells. ---
73  1991 The use of beta-galactosidase fusion proteins encoding the early region 1 transforming proteins of adenovirus type 12 to examine the humoral response in tumour-bearing animals. WT
74  1991 Viral transformation increases vitamin K-dependent gamma-carboxylation of glutamate. Gla, HPC
75  1990 A mitigator sequence in the downstream region of the major late promoter of adenovirus type 12 DNA. ---
76  1990 Cloning of adenovirus type 12 E1 genes into a retroviral vector and their differential splicing in mouse cells. ---
77  1990 Extracts of hamster cells abortively infected with human adenovirus type 12 are competent to support initiation of viral DNA replication. ---
78  1989 Arrangement and expression of integrated adenovirus type 12 DNA in the transformed hamster cell line HA12/7: amplification of Ad12 and c-myc DNAs and evidence for hybrid viral-cellular transcripts. ---
79  1989 Chromatin structure and levels of expression and DNA methylation in the E3 region of chromosomally integrated adenovirus type 12 DNA. ---
80  1989 Defect of adenovirus type 12 replication in hamster cells: absence of transcription of viral virus-associated and L1 RNAs. VA
81  1989 Embryonal neuroepithelial tumors induced by human adenovirus type 12 in rodents. 1. Tumor induction in the peripheral nervous system. ---
82  1989 Embryonal neuroepithelial tumors induced by human adenovirus type 12 in rodents. 2. Tumor induction in the central nervous system. ---
83  1989 Modulation of major histocompatibility complex (MHC) class I genes in adenovirus 12 transformed cells: interferon-gamma increases class I expression by a mechanism that circumvents E1A induced-repression and tumor necrosis factor enhances the effect of interferon-gamma. IFN-gamma, MHC, TNF
84  1989 Recombination in hamster cell nuclear extracts between adenovirus type 12 DNA and two hamster preinsertion sequences. ---
85  1989 The high sensitivity of cells transformed by E1A gene of adenovirus type 12 to diacylglycerol-mediated cell killing. DLG
86  1989 Transgenic mouse model for human gastric carcinoma. ---
87  1988 A fragile site in the human U2 small nuclear RNA gene cluster is revealed by adenovirus type 12 infection. ---
88  1988 Activation of the human beta interferon gene by the adenovirus type 12 E1B gene. CEF, HEK
89  1988 Adenovirus type 12 E1A gene represses accumulation of MHC class I mRNAs at the level of transcription. MHC
90  1988 Analysis of an adenovirus type 12 temperature-sensitive mutant defective in interferon induction. IFN
91  1988 Expression of hamster MHC class I antigens in transformed cells and tumours induced by human adenoviruses. ---
92  1988 Integration of foreign DNA into mammalian genome can be associated with hypomethylation at site of insertion. ---
93  1988 Isolation and characterization of adenovirus type 12 E1 host-range mutants defective for growth in nontransformed human cells. hr
94  1988 Predominant association of adenovirus type 12 DNA with human chromosome 1 early in productive infection. ---
95  1988 Regulation of major histocompatibility class I gene expression at the level of transcription in highly oncogenic adenovirus transformed rat cells. MHC
96  1988 Selective cytotoxicity of phospholipids and diacylglycerols to rat 3Y1 fibroblasts transformed by adenovirus type 12 or its E1A gene. PC
97  1988 Suppression of block to entry into S phase in cell-cycle mutants of rat 3Y1 fibroblasts after transformation by adenovirus type 12. ts
98  1988 Tumorigenicity of adenovirus-transformed cells: collagen interaction and cell surface laminin are controlled by the serotype origin of the E1A and E1B genes. ---
99  1987 E1B functions of type C adenoviruses play a role in the complementation of blocked adenovirus type 12 DNA replication and late gene transcription in hamster cells. Ad2
100  1987 Induction of cellular DNA synthesis by adenovirus type 12 in a set of temperature-sensitive mutants of rat 3Y1 fibroblasts blocked in G1 phase. ts