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Abbreviation : BK
Long Form : bradykinin
No. Year Title Co-occurring Abbreviation
2020 3D Printed Multiplexed Competitive Migration Assays with Spatially Programmable Release Sources. EGF
2020 Angiotensin-Converting Enzyme Inhibitor Rapidly Ameliorates Depressive-Type Behaviors via Bradykinin-Dependent Activation of Mammalian Target of Rapamycin Complex 1. ACEIs
2020 Autocrine Bradykinin Release Promotes Ischemic Preconditioning-Induced Cytoprotection in Bovine Aortic Endothelial Cells. BAECs, BKR1, BKR2, PC
2020 Bradykinin Receptors Play a Critical Role in the Chronic Post-ischaemia Pain Model. CPIP, CRPS I, i.p, i.pl, i.t
2020 Evaluation of bradykinin, VEGF, and EGF biomarkers in gingival crevicular fluid and comparison of PhotoBioModulation with conventional techniques in periodontitis: a split-mouth randomized clinical trial. CP, EGF, PBM, PBM, VEGF
2020 Fine particulate matter increases airway hyperresponsiveness through kallikrein-bradykinin pathway. AHR, B2R, hASMCs, KLK14
2020 In Vitro Pharmacological Profile of a New Small Molecule Bradykinin B2 Receptor Antagonist. ---
2020 Increases in [IP3]i aggravates diastolic [Ca2+] and contractile dysfunction in Chagas' human cardiomyocytes. CC, IP3Rs, SR, Xest-C
2020 Measurement of Bradykinin Formation and Degradation in Blood Plasma: Relevance for Acquired Angioedema Associated With Angiotensin Converting Enzyme Inhibition and for Hereditary Angioedema Due to Factor XII or Plasminogen Gene Variants. ACE, AE, C1-INH, FXII, HAE, iBK, tPA
10  2020 Modulation of proteomic and inflammatory signals by Bradykinin in podocytes. PG
11  2020 Perioperative Management of Patients With Hereditary Angioedema With Special Considerations for Cardiopulmonary Bypass. ACE, C1-INH, HAE
12  2020 Pharmacological Effects of a Novel Bradykinin-Related Peptide (RR-18) from the Skin Secretion of the Hejiang Frog (Ordorrana hejiangensis) on Smooth Muscle. BRPs, HPLC, MS/MS
13  2020 PIP2 Mediated Inhibition of TREK Potassium Currents by Bradykinin in Mouse Sympathetic Neurons. 2-APB, IM, IRIL, mSCG, PKC, PLC, RIL, SCG, SFA, TWIK
14  2020 Roles for heterodimerization of APJ and B2R in promoting cell proliferation via ERK1/2-eNOS signaling pathway. B2R, Co-IP, eNOS, HEK, HUVECs, PLA
15  2020 Sensitization of small-diameter sensory neurons is controlled by TRPV1 and TRPA1 association. NGF, PGE2, PKA
16  2020 Understanding the Pathophysiology of COVID-19: Could the Contact System Be the Key? ACE, Ang II, CS, FXII, RAS
17  2020 Upregulation of Proinflammatory Bradykinin Peptides in Systemic Lupus Erythematosus and Rheumatoid Arthritis. SLE
18  2020 Vasomotor effects of 5-hydroxytryptamine, histamine, angiotensin II, acetylcholine, noradrenaline, and bradykinin on the cerebral artery of bottlenose dolphin (Tursiops truncatus). 5-HT, ACh, Ang, HIS, NA
19  2020 What would Sergio Ferreira say to your physician in this war against COVID-19: How about kallikrein/kinin system? ACE2, COVID-19, DABK, RAS
20  2020 [Application of intravenous injection of tranexamic acid combined with local use of tranexamic acid cocktail in intertrochanteric fracture fixation]. MA, PFNA, PGE2, TXA, VAS
21  2019 Acquired complement C1 esterase inhibitor deficiency in a patient with a rare SERPING1 variant with unknown significance. AE
22  2019 Activation of Kv7 Potassium Channels Inhibits Intracellular Ca2+ Increases Triggered By TRPV1-Mediated Pain-Inducing Stimuli in F11 Immortalized Sensory Neurons. CAP, TRPV1
23  2019 Altered Renal Vascular Responsiveness to Vasoactive Agents in Rats with Angiotensin II-Dependent Hypertension and Congestive Heart Failure. ACF, ACh, Ang II, CHF, EETs, NE, RBF, TGRs
24  2019 Angioedema: a rare and sometimes delayed side effect of angiotensin-converting enzyme inhibitors. ACE, AE
25  2019 Bradykinin alleviates DR retinal endothelial injury by regulating HMGB-1/NF-kappaB pathway. DR, ELISA, hRECs, IL-1beta, LDH, SOD, TNF-alpha, VEGF
26  2019 Bradykinin and interleukin-1beta synergistically increase the expression of cyclooxygenase-2 through the RNA-binding protein HuR in rat dorsal root ganglion cells. COX-2, DRG, IL-1beta
27  2019 Bradykinin contributes to immune liver injury via B2R receptor-mediated pathways in trichloroethylene sensitized mice: A role in Kupffer cell activation. KCs, KKS, OMLDT, TCE
28  2019 Bradykinin promotes proliferation, migration, and invasion of cervical cancer cells through STAT3 signaling pathways. B2R, CC
29  2019 Bradykinin sensitizes the cough reflex via a B2 receptor dependent activation of TRPV1 and TRPA1 channels through metabolites of cyclooxygenase and 12-lipoxygenase. 12-LOX, COX, i.c.v
30  2019 Calcium Release from Endoplasmic Reticulum Involves Calmodulin-Mediated NADPH Oxidase-Derived Reactive Oxygen Species Production in Endothelial Cells. CaMKII, ER, NOX, ROS
31  2019 Efficacy of a phenol derivative, isopropyl vanillate, as an anti-inflammatory agent: A new small molecule inhibitor of COX and neutrophil migration. COX-2, Dex, Hist, ISP-VT, MPO, PGE2
32  2019 Evidence against a crucial role of renal medullary perfusion in blood pressure control of hypertensive rats. MBF, SHR
33  2019 Excitatory effect of bradykinin on intrinsic neurons of the rat heart. Oxo-M
34  2019 Hereditary Angioedema: Insights into inflammation and allergy. HAE
35  2019 Heteromerization fingerprints between bradykinin B2 and thromboxane TP receptors in native cells. B2R, Co-IP, GPCRs, PLA, TP, TXA2, VSMC
36  2019 Increased expression of TRPV1 in patients with acute or chronic cough after lung cancer surgery. PGE2, VAS
37  2019 Intracellular Ca2+ mobilization pathway via bradykinin B1 receptor activation in rat trigeminal ganglion neurons. TG
38  2019 Mycoplasma hyopneumoniae surface-associated proteases cleave bradykinin, substance P, neurokinin A and neuropeptide Y. NKA, NPY, SP
39  2019 Neuroprotective Effects of Dehydroepiandrosterone Sulfate Through Inhibiting Expression of Matrix Metalloproteinase-9 from Bradykinin-Challenged Astroglia. CNS, DHEAS, MMPs, NOX, RBA, ROS
40  2019 Neuroprotective Effects of Kinin B2 Receptor in Organotypic Hippocampal Cultures of Middle-Aged Mice. KKS, OHCs
41  2019 Osteoarthritic pain model influences functional outcomes and spinal neuropeptidomics: A pilot study in female rats. CCLT, CGRP, COMBO, DMM, MIA, PWT, SP, SST, SWB
42  2019 Oxidative stress markers in patients with hereditary angioedema. AGEs, AOPPs
43  2019 Pulsatile antagonism on bradykinin 2-receptor (BK2R) by icatibant triggers the most effective kinin-dependent post-conditioning on rat hearts. BK2R, CF, DLVP, I/R, IM, PC, RISK, SD
44  2019 Retinal proteome associated with bradykinin-induced edema. DME, GO
45  2019 Serum bradykinin levels as a diagnostic marker in cervical cancer with a potential mechanism to promote VEGF expression via BDKRB2. BDKRB2, CC, HUVEC, SCCA, VEGF
46  2019 TGF-beta1 induced up-regulation of B1 kinin receptor promotes antifibrotic activity in rat cardiac myofibroblasts. CF, CMF, PKC, PLA2, PLC
47  2019 The expression of bradykinin and its receptors in spinal cord ischemia-reperfusion injury rat model. ELISA, RT-qPCR, SCII, SD
48  2018 Anti-hyperalgesic effects of two sphingosine derivatives in different acute and chronic models of hyperalgesia in mice. CFA, LPS, PGE2, PSNL
49  2018 Bifunctional fusion proteins containing the sequence of the bradykinin homologue maximakinin: activities at the rat bradykinin B2 receptor. B2R, EGFP, HSA, MK
50  2018 Bifunctional ligands of the bradykinin B2 and B1 receptors: An exercise in peptide hormone plasticity. B1R, B2R
51  2018 Blockade of Bradykinin receptors worsens the dystrophic phenotype of mdx mice: differential effects for B1 and B2 receptors. B1R, B2R, DMD, KKS
52  2018 Bradykinin B2 Receptor Contributes to Inflammatory Responses in Human Endothelial Cells by the Transactivation of the Fibroblast Growth Factor Receptor FGFR-1. B2R, FGF-2, FGFR1, HUVEC
53  2018 Bradykinin B2 receptors play a neuroprotective role in Hypoxia/reoxygenation injury related to pyroptosis pathway. B1R, B2R, GSDMD, PI, RT-qPCR
54  2018 Bradykinin mediates myogenic differentiation in murine myoblasts through the involvement of SK1/Spns2/S1P2 axis. S1P, SK, Spns2
55  2018 Bradykinin mediates the association of collecting duct cells to form migratory colonies, through B2 receptor activation. B2R, CD
56  2018 Bradykinin potentially stimulates cell proliferation in rabbit corneal endothelial cells through the ZO‑1/ZONAB pathway. CECs, PCNA, RCEC
57  2018 Bradykinin receptor in immune-mediated renal tubular injury in trichloroethylene-sensitized mice: Impact on NF-kappaB signaling pathway. Cr, KKS, TCE
58  2018 Bradykinin Receptors in Ischemic Injury. KKS
59  2018 Bradykinin Sequestration by Plasmodium berghei Infected Erythrocytes Conditions B2R Signaling and Parasite Uptake by Fetal Trophoblasts. B2R, IE, IL
60  2018 Bradykinin Stimulates Renal Na+ and K+ Excretion by Inhibiting the K+ Channel (Kir4.1) in the Distal Convoluted Tubule. DCT, NCC
61  2018 Bradykinin system is involved in endometriosis-related pain through endothelin-1 production. BKR, ESC
62  2018 Changes in coagulation factor XII and its function during aortic arch surgery for acute aortic dissection-a prospective observational study. AAD, CI, FFP, OR, PRBCs
63  2018 Comparing Pathways of Bradykinin Formation in Whole Blood From Healthy Volunteers and Patients With Hereditary Angioedema Due to C1 Inhibitor Deficiency. FXIIa, iBK, tPA
64  2018 D-Arg0-Bradykinin-Arg-Arg, a Latent Vasoactive Bradykinin B2 Receptor Agonist Metabolically Activated by Carboxypeptidases. ACE, B2R, CPs
65  2018 Effects of bradykinin on TGF‑beta1‑induced epithelial‑mesenchymal transition in ARPE‑19 cells. EMT, PVR, RPE, SMA
66  2018 Enhancement of bradykinin-induced relaxation by focal brain ischemia in the rat middle cerebral artery: Receptor expression upregulation and activation of multiple pathways. ChTX, MCA, NO
67  2018 Expression and function of TLR4- induced B1R bradykinin receptor on cardiac fibroblasts. CF, CMF, DAKD, ECM, TLR4
68  2018 Important role of endothelium-dependent hyperpolarization in the pulmonary microcirculation in male mice: implications for hypoxia-induced pulmonary hypertension. EDH, NO, PH
69  2018 Involvement of Bradykinin B2 Receptor in Pathological Vascularization in Oxygen-Induced Retinopathy in Mice and Rabbit Cornea. B2R, OIR
70  2018 Multiple Inhibitory Mechanisms of Lidocaine on Bradykinin Receptor Activity in Model Sensory Neurons. LAs
71  2018 N-methyl pyrrolidone promotes ankle fracture healing by inhibiting inflammation via suppression of the mitogen-activated protein kinase signaling pathway. COX-2, IL, iNOS, NMP, RT-qPCR
72  2018 Phosphorylation of epidermal growth factor receptor at serine 1047 in cultured lung alveolar epithelial cells by bradykinin B2 receptor stimulation. DUSP5, EGFR, ERK, GPCRs, p38 MAPK, Ser1047, TLR5, TNF-alpha
73  2018 Propofol Promotes Ankle Fracture Healing in Children by Inhibiting Inflammatory Response. IL, qRT-PCR
74  2018 Protocols to Assess Coagulation Following In Vitro Infection with Hemorrhagic Fever Viruses. DIC, FXII, HFV, HUVECs, PK, TF
75  2018 Sinomenine Regulates Inflammatory Response and Oxidative Stress via Nuclear Factor kappa B (NF-kappaB) and NF-E2-Related Factor 2 (Nrf2) Signaling Pathways in Ankle Fractures in Children. IL, NF-kappaB, Nrf2, TNF-alpha
76  2018 Sympatho-excitatory response to pulmonary chemosensitive spinal afferent activation in anesthetized, vagotomized rats. CAP, HR, MAP, RSNA
77  2018 Transforming growth factor-beta enhances Rho-kinase activity and contraction in airway smooth muscle via the nucleotide exchange factor ARHGEF1. hASMCs, SrcFK, TGF-beta
78  2018 Unraveling endothelin-1 induced hypercontractility of human pulmonary artery smooth muscle cells from patients with pulmonary arterial hypertension. ET-1, HPASMC, MMCPP, PAH
79  2018 [Microinjection of endomorphin-1 in the ventrolateral periaqueductal gray induces descending inhibition of cardiac nociception by activating mu-opioid receptor in rats]. EM1, EMG, vlPAG
80  2017 A kallikrein-targeting RNA aptamer inhibits the intrinsic pathway of coagulation and reduces bradykinin release. APTT, FXIIa, HK, SELEX
81  2017 An ABC of the Warning Signs of Hereditary Angioedema. HAE
82  2017 Bradykinin Promotes Cell Proliferation, Migration, Invasion, and Tumor Growth of Gastric Cancer Through ERK Signaling Pathway. B1R, B2R, GC, MMP
83  2017 Bradykinin stimulates protein kinase D-mediated colonic myofibroblast migration via cyclooxygenase-2 and heat shock protein 27. COX-2, HSP27, PKD
84  2017 Bradykinin/B2 receptor activation regulates renin in M-1 cells via protein kinase C and nitric oxide. B2R, CD, KKS, NO, PKA, PKC, RAS
85  2017 Cardiac sympathetic afferent reflex control of cardiac function in normal and chronic heart failure states. CHF, EDPVR, ESPVR, HR, LV, LVEDP, LVEDP, LVSP, MI, P-V
86  2017 Cellular basis of angiotensin-(1-7)-induced augmentation of left ventricular functional performance in heart failure. Ang II, HF, LV, NO
87  2017 Effects of Simvastatin Beyond Dyslipidemia: Exploring Its Antinociceptive Action in an Animal Model of Complex Regional Pain Syndrome-Type I. ASICs, CPIP, HMG-CoA, IR, PGE2, TRP
88  2017 Evaluation of anti-inflammatory potential of aqueous extract and polysaccharide fraction of Thuja occidentalis Linn. in mice. AE, COX, Dex, Hist, IL-6, iNOS, PGE2, PLS, TNF-alpha
89  2017 Factor XII-Driven Inflammatory Reactions with Implications for Anaphylaxis. FXII, HAE, polyP
90  2017 G Protein-Coupled Kinin Receptors and Immunity Against Pathogens. FXII, HK, KKS, PK
91  2017 Hypertension alters the endothelial-dependent biphasic response of bradykinin in isolated Microminipig basilar artery. Ang, MMPig
92  2017 Inhibition of platelet aggregation ex vivo is repressed in apolipoprotein E deficient mice. ET-1, WT
93  2017 Involvement of the Bradykinin B1 Receptor in Microglial Activation: In Vitro and In Vivo Studies. AD, B1R, B2R, NO, TNF-alpha
94  2017 Ipomoea pes-caprae (L.) R. Br (Convolvulaceae) relieved nociception and inflammation in mice - A topical herbal medicine against effects due to cnidarian venom-skin contact. ISA
95  2017 Mast Cell Coupling to the Kallikrein-Kinin System Fuels Intracardiac Parasitism and Worsens Heart Pathology in Experimental Chagas Disease. B2Rs, DXS, ETAR, ETBR, FXII, HCP, KKS, MCs, TLR2
96  2017 Modulation of cardiac vagal tone by bradykinin acting on nucleus ambiguus. ---
97  2017 Moving pieces in a cryptomic puzzle: Cryptide from Tityus serrulatus Ts3 Nav toxin as potential agonist of muscarinic receptors. ACEI, mAChRs, NO
98  2017 Nerve growth factor derivative NGF61/100 promotes outgrowth of primary sensory neurons with reduced signs of nociceptive sensitization. B2R, CGRP, DRG, NGF, SP, TRPV1
99  2017 Panicolytic-like action of bradykinin in the dorsal periaqueductal gray through mu-opioid and B2-kinin receptors. ACE, B2R, dPAG, MOR
100  2017 Relationship between Angiotensin Converting Enzyme, Apelin, and New-Onset Atrial Fibrillation after Off-Pump Coronary Artery Bypass Grafting. ACE, Ang II, CRP, MDA, OPCABG, POAF