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Abbreviation : BMP4
Long Form : bone morphogenetic protein 4
No. Year Title Co-occurring Abbreviation
2021 A Two-Step Protocol to Erase Human Skin Fibroblasts and Convert Them into Trophoblast-like Cells. 5-aza-CR
2021 Activin/Nodal/TGF-β Pathway Inhibitor Accelerates BMP4-Induced Cochlear Gap Junction Formation During in vitro Differentiation of Embryonic Stem Cells. Cx26, GJB2, iPSCs
2021 Anophthalmia, Global Developmental Delay, and Severe Dysphagia in a Young Girl With 14q22q23 Microdeletion Syndrome. OTX2, SIX1, SIX6
2021 BMP4 augments the survival of hepatocellular carcinoma (HCC) cells under hypoxia and hypoglycemia conditions by promoting the glycolysis pathway. HCC
2021 BMP4 overexpression induces the upregulation of APP/Tau and memory deficits in Alzheimer's disease. AD, NSE
2021 BMP4-mediated browning of perivascular adipose tissue governs an anti-inflammatory program and prevents atherosclerosis. BAT, PVAT
2021 BMP4-regulated human dental pulp stromal cells promote pulp-like tissue regeneration in a decellularized dental pulp matrix scaffold. dECM, DPSC, RT-PCR, SDS
2021 Bone morphogenetic protein 4 (BMP4) promotes hepatic glycogen accumulation and reduces glucose level in hepatocytes through mTORC2 signaling pathway. BMPs, NAFLD
2021 Bone morphogenetic protein 4 differently promotes distinct VE-cadherin+ precursor stages during the definitive hematopoietic development from embryonic stem cell-derived mesodermal cells. ESCs, Flk1, HECs
10  2021 Bronchial Variation: Anatomical Abnormality May Predispose Chronic Obstructive Pulmonary Disease. COPD, FGF10
11  2021 Chalcone-Supported Cardiac Mesoderm Induction in Human Pluripotent Stem Cells for Heart Muscle Engineering. EHM, hPSCs
12  2021 Combinatorial effect of radium-223 and irreversible electroporation on prostate cancer bone metastasis in mice. IRE, Ra-223
13  2021 Comparison of Genome-Wide DNA Methylation Profiles of Human Fetal Tissues Conceived by in vitro Fertilization and Natural Conception. ART, DMRs, ETP, GO, IL1B, IPA, IVF-ET, KEGG, MFPR, TPO
14  2021 Conophylline Suppresses Angiotensin II-Induced Myocardial Fibrosis In Vitro via the BMP4/JNK Pathway. alpha-SMA, JNK
15  2021 Depletion of aneuploid cells in human embryos and gastruloids. ---
16  2021 Derivation of Mouse Parthenogenetic Advanced Stem Cells. ASCs, EpiSCs, ESCs, LIF, paASCs
17  2021 Dietary Vitamin A Impacts Refractory Telogen. CRABP2, CYP26B1, HFSC, KRT6, WNT7A
18  2021 Divergent dynamics in systemic and tissue-specific metabolic and inflammatory responses during weight loss in subjects with obesity. CRP, GBS, IR, SAT
19  2021 Duloxetine suppresses BMP-4-induced release of osteoprotegerin via inhibition of the SMAD signaling pathway in osteoblasts. OPG, SSRI
20  2021 Effect of fibronectin, FGF-2, and BMP4 in the stemness maintenance of BMSCs and the metabolic and proteomic cues involved. BMSCs, FGF-2, FN, GC-MS, MSCs
21  2021 Endothelial cells exposed to atheroprotective flow secrete follistatin-like 1 protein which reduces transcytosis and inflammation. FSTL1, LDL, NF-kappaB, TNF-alpha
22  2021 Endothelial Nitric Oxide Synthase-Deficient Mice. CSVD, eNOS
23  2021 Fisetin promotes osteoblast differentiation and osteogenesis through GSK-3β phosphorylation at Ser9 and consequent β-catenin activation, inhibiting osteoporosis. ACP6, ALP, Col1alpha1, CTSK, DC-STAMP, GSK-3beta, NFATc1, OCN, Osx, PDS
24  2021 Gene expression pattern of trophoblast-specific transcription factors in trophectoderm by analysis of single-cell RNA-seq data of human blastocyst. hESCs, TB
25  2021 Generation of Trophoblast-Like Cells From Hypomethylated Porcine Adult Dermal Fibroblasts. TR
26  2021 Heparan sulfate promotes differentiation of white adipocytes to maintain insulin sensitivity and glucose homeostasis. HS
27  2021 Histidine decarboxylase deficiency inhibits NBP-induced extramedullary hematopoiesis by modifying bone marrow and spleen microenvironments. CXCL12, G-CSF, HDC, Hif1, N-BP, VCAM-1
28  2021 Identification of bone morphogenetic protein 4 in the saliva after the placement of fixed orthodontic appliance. OTM
29  2021 Intrinsic osteoinductivity of PCL-DA/PLLA semi-IPN shape memory polymer scaffolds. COL1A1, hMSCs, PCLDA, PD, PLLA, semi-IPN, SMPs
30  2021 Metallothionein 3 Promotes Osteoblast Differentiation in C2C12 Cells via Reduction of Oxidative Stress. Dlx5, MTs, ROS
31  2021 Msx1 Heterozygosity in Mice Enhances Susceptibility to Phenytoin-Induced Hypoxic Stress Causing Cleft Palate. ---
32  2021 Okadaic Acid Exposure Induced Neural Tube Defects in Chicken (Gallus gallus) Embryos. Fos, LBP, NTDs, OA, ROS, Shh, SOD
33  2021 Overexpression of Long Non-coding RNA 4933425B07Rik Causes Urinary Malformations in Mice. CAKUT, lncRNAs, PB, RT-PCR, UB
34  2021 Psoralen accelerates osteogenic differentiation of human bone marrow mesenchymal stem cells by activating the TGF-β/Smad3 pathway. ALP, BMSCs, hBMSCs, OPN, RI
35  2021 Recombinant human bone morphogenetic protein-4 enhances tendon-to-bone attachment healing in a murine model of rotator cuff tear. BL, SST, SSTHC, Tb.N, Tb.Sp, Tb.Th, TBA
36  2021 Role of bone morphogenic protein-4 in gestational diabetes mellitus-related hypertension. COX-2, GDM, HT, NADPH, SD, VCAM-1
37  2021 Roles of Melatonin in Goat Hair Follicle Stem Cell Proliferation and Pluripotency Through Regulating the Wnt Signaling Pathway. CTNNB1, gsHFSCs, RORalpha
38  2021 Single Nucleus RNA Sequence (snRNAseq) Analysis of the Spectrum of Trophoblast Lineages Generated From Human Pluripotent Stem Cells in vitro. snRNAseq, TB
39  2021 Spatial Stem Cell Fate Engineering via Facile Morphogen Localization. CM, EpiC, hPSCs
40  2021 Strategies for differentiation of hiPSCs into dental epithelial cell lineage. DECs, EBs, hDPSCs, hiPSCs, iPSCs, KSFM, RA
41  2021 Stromal cells in the tumor microenvironment promote the progression of oral squamous cell carcinoma. CXCL, CXCL1, FOS, HDFs, ICAM-1, IL, INS, MAPK3, NGF, OSCC, PIK3CA, TME
42  2021 TGFβ/cyclin D1/Smad-mediated inhibition of BMP4 promotes breast cancer stem cell self-renewal activity. TNBCs
43  2021 The Relationship Between Circulating Bone Morphogenetic Protein-4 and Inflammation Cytokines in Patients Undergoing Thoracic Surgery: A Prospective Randomized Study. IL, TNF-alpha
44  2021 Toll-Like Receptor 2 (TLR2) Knockout Abrogates Diabetic and Obese Phenotypes While Restoring Endothelial Function via Inhibition of NOX1. eNOS, T2DM, WT
45  2021 Zbtb7a and Zbtb7b: Opening naïve loci to reprogram ESCs. ESCs, PNT
46  2020 A Concise Review on Induced Pluripotent Stem Cell-Derived Cardiomyocytes for Personalized Regenerative Medicine. CMs, EBs, ESCs, iPSCs
47  2020 Actions of putative embryokines on development of the preimplantation bovine embryo to the blastocyst stage. CNP, JAK, LIF, STAT3
48  2020 Activation of Canonical BMP4-SMAD7 Signaling Suppresses Breast Cancer Metastasis. ---
49  2020 Analysis of Wnt7B and BMP4 expression patterns in congenital pulmonary airway malformation. CPAM, IHC, qRT-PCR, Wnt7B
50  2020 Basal characterization and in vitro differentiation of putative stem cells derived from the adult mouse ovary. AMH, RA
51  2020 BMP4 and perivascular cells promote hematopoietic differentiation of human pluripotent stem cells in a differentiation stage-specific manner. hPSCs, PVCs
52  2020 BMP4 gene therapy enhances insulin sensitivity but not adipose tissue browning in obese mice. AAV8, WAT
53  2020 BMP4 induces asymmetric cell division in human glioma stem-like cells. ACD, CSCs, GBM, GSCs, SCD
54  2020 BMP4 promotes the metastasis of gastric cancer by inducing epithelial-mesenchymal transition via ID1. EMT, GC
55  2020 BMP4-mediated autophagy is involved in the metastasis of hepatocellular carcinoma via JNK/Beclin1 signaling. HCC
56  2020 Bone Morphogenetic Protein 4 Gene Therapy in Mice Inhibits Myeloma Tumor Growth, But Has a Negative Impact on Bone. AAV8-BMP4
57  2020 Bone Morphogenetic Protein 4 Targeting Glioma Stem-Like Cells for Malignant Glioma Treatment: Latest Advances and Implications for Clinical Application. GSCs
58  2020 Correction for: Bone morphogenetic protein 4 (BMP4) alleviates hepatic steatosis by increasing hepatic lipid turnover and inhibiting the mTORC1 signaling axis in hepatocytes. ---
59  2020 Cytokines Induce Monkey Neural Stem Cell Differentiation through Notch Signaling. CNS, LIF, NSCs, RA
60  2020 Derivation of endothelial cells from porcine induced pluripotent stem cells by optimized single layer culture system. CD31, ECs, iPSCs, piPSCs, PSCs
61  2020 Derivation of oocyte-like cells from putative embryonic stem cells and parthenogenetically activated into blastocysts in goat. COCs, ESCs, RA
62  2020 Deriving Keratinocyte Progenitor Cells and Keratinocytes from Human-Induced Pluripotent Stem Cells. ATRA, EGF, FC, HF, HFBSCs, hiPSCs, hPSC, ICC, ITGA6, ITGB1, KPC, KRT14, KRT15, KRT19, L-AA
63  2020 Detection of circulating BMP5 as a risk factor for Barrett's esophagus. BE, EAC
64  2020 Effect of Human Testicular Cells Conditioned Medium on In Vitro Maturation and Morphology of Mouse Oocytes. ESCs, GDF9, GV, hTCCM, IVF, IVM, LIF, MII, PMSG, PVS, SCF, TCCM, TCs
65  2020 Effect of the Abnormal Expression of BMP-4 in the Blood of Diabetic Patients on the Osteogenic Differentiation Potential of Alveolar BMSCs and the Rescue Effect of Metformin: A Bioinformatics-Based Study. BMSCs, GO, KEGG, T2DM
66  2020 Expression and distribution of bone morphogenetic protein 4 and its antagonist Noggin in the skin of Kazakh sheep (Ovis aries) with a white and brown coat color. IHC, qPCR
67  2020 Functional study of novel PAX9 variants: The paired domain and non-syndromic oligodontia. PAX9
68  2020 GATA3 Mediates a Fast, Irreversible Commitment to BMP4-Driven Differentiation in Human Embryonic Stem Cells. hESCs
69  2020 Generation of Keratinocytes from Human Induced Pluripotent Stem Cells Under Defined Culture Conditions. hESCs, hiPSCs
70  2020 Grading TESI: Crypt and villus formation in tissue-engineered small intestine alters with stem/progenitor cell source. FOXF1, Ihh, SHH, TESI
71  2020 Human Caesarean scar-derived feeder cells: a novel feeder cell type for culturing human pluripotent stem cells without exogenous basic fibroblast growth factor supplementation. COL1A1, FGF-2, FN1, hPSCs, HSFs, INHBA, TGFB1
72  2020 Icariin Accelerates Fracture Healing via Activation of the WNT1/β-catenin Osteogenic Signaling Pathway. ALP, BAP, BMP-2, Cbfalpha1, OC, rBMSCs, TRACP-5b
73  2020 Impact of long-lasting spontaneous physical activity on bone morphogenetic protein 4 in the heart and tibia in murine model of heart failure. WT
74  2020 Increased mesodermal and mesendodermal populations by BMP4 treatment facilitates human iPSC line differentiation into a cardiac lineage. EBs, hiPS-CMs
75  2020 Inhibitory effect of the TSG-6 on the BMP-4/Smad signaling pathway and odonto/osteogenic differentiation of dental pulp stem cells. DPSCs, Smad
76  2020 Investigate the Odontogenic Differentiation and Dentin-Pulp Tissue Regeneration Potential of Neural Crest Cells. DMP1, DSPP, iPSC
77  2020 Investigation of Genetic Polymorphisms in BMP2, BMP4, SMAD6, and RUNX2 and Persistent Apical Periodontitis. BMP-2, PAP, SMAD6, SNPs
78  2020 MicroRNA‑431 inhibits the expression of surfactant proteins through the BMP4/activin/TGF‑β signaling pathway by targeting SMAD4. SMAD4, SPs
79  2020 miR-18a Inhibits BMP4 and HIF-1α Normalizing Brain Arteriovenous Malformations. ADAM10, ALK, AVMs, BECs, miR-18a, MMP-2, TSP-1, VEGF
80  2020 Modeling Klinefelter Syndrome Using Induced Pluripotent Stem Cells Reveals Impaired Germ Cell Differentiation. GDNF, iPSCs, KS, RA, SCF
81  2020 Overexpression of Fgf8 in the epidermis inhibits hair follicle development. FGF8, Shh
82  2020 Pantoprazole impairs fracture healing in aged mice. PPIs
83  2020 Regulation of bone morphogenetic protein 4 on epithelial tissue. BMPs
84  2020 Restoring BMP4 expression in vascular endothelial progenitors ameliorates maternal diabetes-induced apoptosis and neural tube defects. NTDs, Tg
85  2020 RNA sequencing reveals BMP4 as a basis for the dual-target treatment of diabetic retinopathy. 4-HNE, AGEs, DR, SMAD9, VEGF
86  2020 Sequential growth factor releasing double cryogel system for enhanced bone regeneration. DC, GC, GH, VEGF
87  2020 Stimulation of Epithelial Sodium Channels in Endothelial Cells by Bone Morphogenetic Protein-4 Contributes to Salt-Sensitive Hypertension in Rats. ENaC, Nedd4-2, p38 MAPK, SGK1, SS
88  2020 Stress erythropoiesis: definitions and models for its study. ---
89  2020 The Attenuating Effect of the Intraovarian Bone Morphogenetic Protein 4 on Age-Related Endoplasmic Reticulum Stress in Chicken Follicular Cells. ER, GCs, PHFs
90  2020 The differentiation effect of bone morphogenetic protein (BMP) on human amniotic epithelial stem cells to express ectodermal lineage markers. BMP, hAECs
91  2020 Thermoresponsive gel for sustained release of BMP4 to inhibit corneal neovascularization. CNV, EPL
92  2020 Tissue-specific mesenchymal stem cell-dependent osteogenesis in highly porous chitosan-based bone analogs. AD-MSCs, ALP, BM-MSCs, Col I, MSCs, OCN, SOST, WJ-MSCs
93  2020 Use of a human embryonic stem cell model to discover GABRP, WFDC2, VTCN1 and ACTC1 as markers of early first trimester human trophoblast. ACTC1, hESCs, WFDC2
94  2020 [Screen and Function Study of the Key Regulative Odontogenic Genes in Mice]. ALP, ALZ, FGF8, LEF1, SHH
95  2019 Acute upregulation of bone morphogenetic protein-4 regulates endogenous cell response and promotes cell death in spinal cord injury. CSPGs, NPCs, OPCs, SCI
96  2019 All-trans retinoic acid suppresses bone morphogenetic protein 4 in mouse diabetic nephropathy through a unique retinoic acid response element. ATRA, DN, RARalpha, RAREs, RXR
97  2019 An Improved Two-Step Protocol for Trophoblast Differentiation of Human Pluripotent Stem Cells. CTB, EVT, hCG, hPSCs, STB
98  2019 Analysis of MiRNA-17 and MiRNA-146 Expression During Differentiation of Spermatogonial Stem Like Cells Derived from Mouse Bone Marrow Mesenchymal Stem Cells. bFGF, BMSCs, LIF, miRNAs, PGC like cells, RA, SSC like cells
99  2019 Association between BMP4 expression and pathology, CT characteristics and prognosis of non-small cell lung cancer. CT, IHC, mRNA, NSCLC, OS, PFS, qPCR
100  2019 Association of growth performance and body conformational traits with BMP4 gene variation in Barki lambs. PCR-SSCP