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Abbreviation : BuChE
Long Form : butyrylcholinesterase
No. Year Title Co-occurring Abbreviation
2021 Amaryllidaceae Alkaloids of Norbelladine-Type as Inspiration for Development of Highly Selective Butyrylcholinesterase Inhibitors: Synthesis, Biological Activity Evaluation, and Docking Studies. AChE, AD, BBB, CNS, hBuChE
2021 Ameliorative Role of Cerium Oxide Nanoparticles Against Fipronil Impact on Brain Function, Oxidative Stress, and Apoptotic Cascades in Albino Rats. BCL-2, CeNPs, FIP, GFAP, GPx, Iba1, MDA, NO, NSE, ROS, SOD
2021 Aryl N-[ω-(6-Fluoroindol-1-yl)alkyl]carbamates as Inhibitors of Fatty Acid Amide Hydrolase, Monoacylglycerol Lipase, and Butyrylcholinesterase: Structure-Activity Relationships and Hydrolytic Stability. AChE, FAAH, MAGL
2021 Bee venom attenuates neurodegeneration and motor impairment and modulates the response to L-dopa or rasagiline in a mice model of Parkinson's disease. DA, MCP-1, MDA, NO, PD, PON1, TAC, TNF-alpha
2021 Biphenylalkoxyamine Derivatives-Histamine H3 Receptor Ligands with Butyrylcholinesterase Inhibitory Activity. AD, H3Rs
2021 Chemical Composition and Anticholinesterase Activity of the Essential Oil of Leaves and Flowers from the Ecuadorian Plant Lepechinia paniculata (Kunth) Epling. AChE, EO, GC-MS
2021 Children Environmentally Exposed to Agrochemicals in Rural Areas Present Changes in Oxidative Status and DNA Damage. Cr, GSH-Px, GST, MDA, MN, Ni
2021 Cholinesterase inhibitory activity of tinosporide and 8-hydroxytinosporide isolated from Tinospora cordifolia: In vitro and in silico studies targeting management of Alzheimer's disease. AChE
2021 Chromone-lipoic acid conjugate: Neuroprotective agent having acceptable butyrylcholinesterase inhibition, antioxidant and copper-chelation activities. AD, ROS
10  2021 Copper(II) complexes with meclofenamate ligands: Structure, interaction with DNA and albumins, antioxidant and anticholinergic activity. ABTS, AChE, CT, DPPH, EB, Na-mclf, py, SAs
11  2021 Design and synthesis of new carbamates as inhibitors for fatty acid amide hydrolase and cholinesterases: Molecular dynamic, in vitro and in vivo studies. ACh, AChE, AD, ChEIs, ChEs, FAAH
12  2021 Design, synthesis and biological assessment of new 1-benzyl-4-((4-oxoquinazolin-3(4H)-yl)methyl) pyridin-1-ium derivatives (BOPs) as potential dual inhibitors of acetylcholinesterase and butyrylcholinesterase. AChE, AD, BOP-1, BOPs
13  2021 Design, synthesis and biological evaluation of naringenin carbamate derivatives as potential multifunctional agents for the treatment of Alzheimer's disease. AChE, AD, CAS, PAS
14  2021 Design, synthesis and biological evaluation of novel deoxyvasicinone-indole as multi-target agents for Alzheimer's disease. AChE, AD
15  2021 Design, synthesis and evaluation of dihydropyranoindole derivatives as potential cholinesterase inhibitors against Alzheimer's disease. AChE, CAS, PAS
16  2021 Design, synthesis, and biological evaluation of new urolithin amides as multitarget agents against Alzheimer's disease. AChE, MAO-B
17  2021 Design, synthesis, and cholinesterase inhibition assay of liquiritigenin derivatives as anti-Alzheimer's activity. 3a-3p, AChE
18  2021 Discovery of multifunctional anti-Alzheimer's agents with a unique mechanism of action including inhibition of the enzyme butyrylcholinesterase and γ-aminobutyric acid transporters. GATs
19  2021 Discovery of new phenyl sulfonyl-pyrimidine carboxylate derivatives as the potential multi-target drugs with effective anti-Alzheimer's action: Design, synthesis, crystal structure and in-vitro biological evaluation. AChE, AD, BBB, DLS, MTDL
20  2021 Effect of N-acetylcysteine on attenuation of chlropyrifos and its methyl analogue toxicity in male rats. AChE, ATPase, CA, CAT, CPF-M, CYC-R, GST, LPO, MI, MNPCE, NAC, NCE, NO, PCE, PON
21  2021 Effects of Peroral Omega-3 Fatty Acid Supplementation on Cerebrospinal Fluid Biomarkers in Patients with Alzheimer's Disease: A Randomized Controlled Trial-The OmegAD Study. AChE, AD, CSF, MMSE, NfL, PUFAs, sIL-1RII
22  2021 Fatty acid composition, enzyme inhibitory effect, antioxidant and anticancer activity of extract from Saponaria prostrata WILLD. subsp. anatolica HEDGE. AChE, AG, FRAP, GC-MS, qRT-PCR, SPA
23  2021 Hydrazones of 4-(Trifluoromethyl)benzohydrazide as New Inhibitors of Acetyl- and Butyrylcholinesterase. AChE
24  2021 In-vitro evaluation of antioxidant and anticholinesterase activities of novel pyridine, quinoxaline and s-triazine derivatives. ACh, AChE, AD, CAS, CD, PAS
25  2021 Interactions between Ginkgo biloba L. and Scutellaria baicalensis Georgi in multicomponent mixtures towards cholinesterase inhibition and ROS scavenging. AChE, AD
26  2021 Late-Stage Modification of Medicine: Pd-Catalyzed Direct Synthesis and Biological Evaluation of N-Aryltacrine Derivatives. AChE
27  2021 Marine-Derived Compounds with Anti-Alzheimer's Disease Activities. AChE, AD
28  2021 Metabolic depletion of synaptosomal enzymes linked with neurotoxicity and ovarian dysfunction by phenolic antioxidants of Croton zambsicus leaves in rats exposed to chronic mixture of anthropogenic toxicant. 51ENT, AChE, C-ZAMB, HPLC, LDH, MAOA
29  2021 Modulatory effects of caffeic acid on purinergic and cholinergic systems and oxi-inflammatory parameters of streptozotocin-induced diabetic rats. AChE, ADA, CA, DM, E-NTPDase
30  2021 Molecular docking and dynamics studies of cigarette smoke carcinogens interacting with acetylcholinesterase and butyrylcholinesterase enzymes of the central nervous system. AChE, CNS, CSC, MDS, MM-PBSA, NNN
31  2021 New benzamide derivatives and their nicotinamide/cinnamamide analogs as cholinesterase inhibitors. AChE
32  2021 Novel 1,2,4-oxadiazole derivatives as selective butyrylcholinesterase inhibitors: Design, synthesis and biological evaluation. AChE, AD, Fig. 1
33  2021 Novel arylcarbamate-N-acylhydrazones derivatives as promising BuChE inhibitors: Design, synthesis, molecular modeling and biological evaluation. ---
34  2021 Novel chrysin derivatives as hidden multifunctional agents for anti-Alzheimer's disease: design, synthesis and in vitro evaluation. AD, BBB, CAS, PAS
35  2021 Novel hydroxybenzylamine-deoxyvasicinone hybrids as anticholinesterase therapeutics for Alzheimer's disease. AChE, AD
36  2021 Occupational use of agrochemicals results in inhibited cholinesterase activity and altered reproductive hormone levels in male farmers from Buea, Cameroon. AChE, FSH
37  2021 Organophosphorus pesticide exposure biomarkers in a Mexican population. AChE, AREase, DAP, OP
38  2021 Selective BuChE Inhibitory Activity, Chemical Composition, and Enantiomeric Content of the Essential Oil from Salvia leucantha Cav. Collected in Ecuador. AChE, EO
39  2021 Synthesis, molecular docking and molecular dynamics studies of novel tacrine-carbamate derivatives as potent cholinesterase inhibitors. AChE
40  2021 Tailored Modeling of Rivastigmine Derivatives as Dual Acetylcholinesterase and Butyrylcholinesterase Inhibitors for Alzheimer's Disease Treatment. AChE, AD, DFT, MD
41  2021 UPLC-PDA-ESI-QTOF-MS/MS fingerprint of purified flavonoid enriched fraction of Bryophyllum pinnatum; antioxidant properties, anticholinesterase activity and in silico studies. AChE, BPFRF, LP
42  2020 A Computational Study of Natural Compounds from Bacopa monnieri in the Treatment of Alzheimer's Disease. AChE, AD
43  2020 A Multi-layered Variable Selection Strategy for QSAR Modeling of Butyrylcholinesterase Inhibitors. ACh, AD, GA, OECD, PLS
44  2020 ABTS On-Line Antioxidant, alpha-Amylase, alpha-Glucosidase, Pancreatic Lipase, Acetyl- and Butyrylcholinesterase Inhibition Activity of Chaenomeles Fruits Determined by Polyphenols and other Chemical Compounds. 15-LOX, AChE
45  2020 Alkaloids of Phaedranassa dubia (Kunth) J.F. Macbr. and Phaedranassa brevifolia Meerow (Amaryllidaceae) from Ecuador and its cholinesterase-inhibitory activity. AChE, GC-MS
46  2020 Aminoalcoholate-driven tetracopper(II) cores as dual acetyl and butyrylcholinesterase inhibitors: Experimental and theoretical elucidation of mechanism of action. PAS
47  2020 An Isoquinolinium Dual Inhibitor of Cholinesterases and Amyloid β Aggregation Mitigates Neuropathological Changes in a Triple-Transgenic Mouse Model of Alzheimer's Disease. AChE, AD, BBB, ChEs
48  2020 Analogues of 2'-hydroxychalcone with modified C4-substituents as the inhibitors against human acetylcholinesterase. AChE, AD, CAS, PAS
49  2020 Anticholinesterase and Antioxidant Activities of Natural Abietane Diterpenoids with Molecular Docking Studies. AChE, AD
50  2020 Aromatic Esters of the Crinane Amaryllidaceae Alkaloid Ambelline as Selective Inhibitors of Butyrylcholinesterase. AChE, BBB, CNS, hBuChE, PAMPA
51  2020 Biochemical aspects of susceptibility to stressors in two small cyprinids Squalius laietanus and Barbus meridionalis from the NW Mediterranean. AChE, CAT, CE, CS, GPx, GR, GST, LDH, PFASs
52  2020 Brazilian native fruit extracts act as preventive agents modulating the purinergic and cholinergic signalling in blood cells and serum in a rat model of metabolic syndrome. AChE, ADA, HPD, IL-6, MetS
53  2020 Cerebrospinal fluid cholinergic biomarkers are associated with postoperative delirium in elderly patients undergoing Total hip/knee replacement: a prospective cohort study. AChE, ASA, AUC, BMI, CAM, ChAT, CSF, IL-6, MDAS, MMSE, PACU, POD, ROC, TNF-alpha
54  2020 Characterization of phenolic profile by LC-ESI-MS/MS and enzyme inhibitory activities of two wild edible garlic: Allium nigrum L. and Allium subhirsutum L. AChE, PCA
55  2020 Chemical composition and selective BuChE inhibitory activity of the essential oils from aromatic plants used to prepare the traditional Ecuadorian beverage horchata lojana. AChE, EOs
56  2020 Chemical Constituents, Antioxidant, Anticholinesterase and Antiproliferative Effects of Algerian Pistacia atlantica Desf. Extracts. AChE, BHA, BHT
57  2020 Chemical Profiling and Cholinesterase Inhibitory Activity of Five Phaedranassa Herb. (Amaryllidaceae) Species from Ecuador. AD
58  2020 Cholinergic Markers and Cytokines in OSA Patients. AChE, FoxP3, HC, OSA, RORc, TGF, Th, Treg
59  2020 Comparative Kinetics of Acetyl- and Butyryl-Cholinesterase Inhibition by Green Tea Catechins|Relevance to the Symptomatic Treatment of Alzheimer's Disease. AChE, AD, ECG, EGC, EGCG
60  2020 Correlation of plasma butyrylcholinesterase concentration with Acethylcholinesterase H353N polymorphism in the inflammatory response of Chagas disease patients. ACh, AChE
61  2020 Design and synthesis of multi-target directed 1,2,3-triazole-dimethylaminoacryloyl-chromenone derivatives with potential use in Alzheimer's disease. AChE, AD, CAS, PAS
62  2020 Design, synthesis and biological evaluation of 2,3-dihydro-5,6-dimethoxy-1H-inden-1-one and piperazinium salt hybrid derivatives as hAChE and hBuChE enzyme inhibitors. AChE
63  2020 Design, Synthesis and Biological Evaluation of Xanthone Derivatives for Possible Treatment of Alzheimer's Disease Based on Multi-Target Strategy. AChE, AChEIs, AD, BBB, CAS, PAS
64  2020 Design, synthesis and evaluation of new chromone-derived aminophosphonates as potential acetylcholinesterase inhibitor. AChE
65  2020 Discovery of 9-phenylacridinediones as highly selective butyrylcholinesterase inhibitors through structure-based virtual screening. 9-PAD, AD
66  2020 Dual Action of Dipyridothiazine and Quinobenzothiazine Derivatives-Anticancer and Cholinesterase-Inhibiting Activity. AChE, AD
67  2020 Exploration of dual fatty acid amide hydrolase and cholinesterase inhibitory potential of some 3-hydroxy-3-phenacyloxindole analogs. AChE, ChEs, FAAH
68  2020 Functionalized aromatic esters of the Amaryllidaceae alkaloid haemanthamine and their in vitro and in silico biological activity connected to Alzheimer's disease. AA, AChE, BBB, hAChE, hBuChE, PAMPA
69  2020 GC/MS Analysis of Alkaloids in Galanthus fosteri Baker and Determination of Its Anticholinesterase Activity. AChE
70  2020 Himalayan Nettle Girardinia diversifolia as a Candidate Ingredient for Pharmaceutical and Nutraceutical Applications-Phytochemical Analysis and In Vitro Bioassays. AChE, LDLR
71  2020 In silico modeling for dual inhibition of acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE) enzymes in Alzheimer's disease. AChE, PLS
72  2020 In Situ Generation of Prussian Blue by MIL-53 (Fe) for Point-of-Care Testing of Butyrylcholinesterase Activity Using a Portable High-Throughput Photothermal Device. PB, POCT, PT
73  2020 Insecticidal and Cholinesterase Activity of Dichloromethane Extracts of Tithonia diversifolia on Atta cephalotes Worker Ants (Formicidae: Myrmicinae). AChE
74  2020 Magnitude of behavioral deficits varies with job-related chlorpyrifos exposure levels among Egyptian pesticide workers. AChE, CPF, OPs, TCPy
75  2020 Multi-target approach for Alzheimer's disease treatment: computational biomolecular modeling of cholinesterase enzymes with a novel 4-N-phenylaminoquinoline derivative reveal promising potentials. AChE, DFT, MD
76  2020 N-1,2,3-triazole-isatin derivatives for cholinesterase and β-amyloid aggregation inhibition: A comprehensive bioassay study. ChE, eeAChE, eqBuChE, hBuChE
77  2020 N-Alkyl-2-[4-(trifluoromethyl)benzoyl]hydrazine-1-carboxamides and Their Analogues: Synthesis and Multitarget Biological Activity. AChE
78  2020 N-[3,5-Bis(trifluoromethyl)phenyl]-5-bromo-2-hydroxybenzamide Analogues: Novel Acetyl- and Butyrylcholinesterase Inhibitors. ---
79  2020 Novel Iodinated Hydrazide-hydrazones and their Analogues as Acetyl- and Butyrylcholinesterase Inhibitors. ---
80  2020 Novel N-benzylpiperidine derivatives of 5-arylisoxazole-3-carboxamides as anti-Alzheimer's agents. AChE, AD
81  2020 Potential Nutraceutical Properties of Leaves from Several Commonly Cultivated Plants. AChE, ChEIs, DPPH
82  2020 Rapalogues as hCES2A Inhibitors: In Vitro and In Silico Investigations. hCES1A, hCES2A
83  2020 Relationship between butyrylcholinesterase activity and lipid parameters in workers occupationally exposed to pesticides. OP
84  2020 Resveratrol oligomers from Paeonia suffruticosa protect mice against cognitive dysfunction by regulating cholinergic, antioxidant and anti-inflammatory pathways. ACh, AChE, CAT, ChAT, IL-1beta, IL-4, IL-6, OGD/R, PSCE, SOD, TNF-alpha
85  2020 Selective acetylcholinesterase inhibitors derived from muscle relaxant dantrolene. AChE
86  2020 Synthesis of Hantzsch Adducts as Cholinesterases and Calcium Flux inhibitors, Antioxidants and Neuroprotectives. AChE
87  2020 Targeting Cannabinoid Receptor Activation and BACE-1 Activity Counteracts TgAPP Mice Memory Impairment and Alzheimer's Disease Lymphoblast Alterations. AD, BACE1, CB
88  2020 The Volatile Chemical Compositions of the Essential Oil/SPME and Enzyme Inhibitory and Radical Scavenging Activities of Solvent Extracts and the Essential oils from Coronilla orientalis Miller and C. varia L. grows in Turkey. AChE, C. orientalis, C. varia, HD, SPME, VOCs
89  2020 Three-dimensional brain-on-chip model using human iPSC-derived GABAergic neurons and astrocytes: Butyrylcholinesterase post-treatment for acute malathion exposure. AChE, iPSC, MT, OPs
90  2020 TV 3326 for Alzheimer's dementia: a novel multimodal ChE and MAO inhibitors to mitigate Alzheimer's-like neuropathology. ACh, AChE, AD, MAO
91  2019 2-Hydroxy-N-phenylbenzamides and Their Esters Inhibit Acetylcholinesterase and Butyrylcholinesterase. AChE
92  2019 A caffeic acid-ferulic acid hybrid compound attenuates lipopolysaccharide-mediated inflammation in BV2 and RAW264.7 cells. CA, COX-2, iNOS, NO, PT, Trm
93  2019 A Simple 3D-Printed Enzyme Reactor Paper Spray Mass Spectrometry Platform for Detecting BuChE Activity in Human Serum. 3D ER-PS
94  2019 Alignment-independent 3D-QSAR and molecular docking studies of tacrine-4-oxo-4H-Chromene hybrids as anti-Alzheimer's agents. AChE, AD, GRIND
95  2019 Amaryllidaceae alkaloids from Narcissus pseudonarcissus L. cv. Dutch Master as potential drugs in treatment of Alzheimer's disease. AChE, GSK-3beta, POP
96  2019 Anti-Alzheimer's multitarget-directed ligands with serotonin 5-HT6 antagonist, butyrylcholinesterase inhibitory, and antioxidant activity. ---
97  2019 Anti-cholinesterase activities of constituents isolated from Lycopodiastrum casuarinoides. AChE
98  2019 Antidiabetic, Anticholinesterase and Antioxidant Activity vs. Terpenoids and Phenolic Compounds in Selected New Cultivars and Hybrids of Artichoke Cynara scolymus L. AChE, dw, UPLC-PDA
99  2019 Antioxidant and Anticholinesterase Activities of Macrosphyra Longistyla (DC) Hiern Relevant in the Management of Alzheimer's Disease. AChE, DPPH, GC-MS
100  2019 Biological Evaluation, Molecular Docking, and SAR Studies of Novel 2-(2,4-Dihydroxyphenyl)-1H- Benzimidazole Analogues. AChE