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Abbreviation : CAFs
Long Form : cancer-associated fibroblasts
No. Year Title Co-occurring Abbreviation
2021 Gold nanoparticles inhibit activation of cancer-associated fibroblasts by disrupting communication from tumor and microenvironmental cells. GNPs, OCs, TME
2020 3D Co-culture of Cancer-Associated Fibroblast with Oral Cancer Organoids. OSCC
2020 A centralized communication network: Recent insights into the role of the cancer associated fibroblast in the development of drug resistance in tumors. ECM
2020 A framework for advancing our understanding of cancer-associated fibroblasts. ---
2020 A new aggressive xenograft model of human colon cancer using cancer-associated fibroblasts. NF, VIM
2020 A new tandem peptide modified liposomal doxorubicin for tumor "ecological therapy". FN, RT-PCR, TAMs, TGI, TME, TMIE
2020 A paracrine activin A-mDia2 axis promotes squamous carcinogenesis via fibroblast reprogramming. ---
2020 A TRACER culture invasion assay to probe the impact of cancer associated fibroblasts on head and neck squamous cell carcinoma cell invasiveness. ECM, HNSCC, MMPs, TRACER
2020 Acidic fibroblast growth factor underlies microenvironmental regulation of MYC in pancreatic cancer. ---
10  2020 Adipose-derived mesenchymal stem cells differentiate into pancreatic cancer-associated fibroblasts invitro. AD-MSCs, iCAF, myCAF, PDAC, TME
11  2020 alpha1,6-Fucosyltransferase (FUT8) regulates the cancer-promoting capacity of cancer-associated fibroblasts (CAFs) by modifying EGFR core fucosylation (CF) in non-small cell lung cancer (NSCLC). CF, CF, NLFs, NSCLC, TME
12  2020 Alterations in the methylome of the stromal tumour microenvironment signal the presence and severity of prostate cancer. BPFs, DMRs, NPFs
13  2020 Altered expression of fibroblast activation protein-alpha (FAP) in colorectal adenoma-carcinoma sequence and in lymph node and liver metastases. BCAT, CRC, FAP, sFAP
14  2020 Angiotensin II type 1 receptor blocker telmisartan inhibits the development of transient hypoxia and improves tumour response to radiation. ---
15  2020 Anti-EGFR Therapy Induces EGF Secretion by Cancer-Associated Fibroblasts to Confer Colorectal Cancer Chemoresistance. EGFR, MAPK
16  2020 Anti-Metastatic Effects of Plant Sap-Derived Extracellular Vesicles in a 3D Microfluidic Cancer Metastasis Model. DMS-EVs, ECM
17  2020 Antifibrotic therapy to normalize the tumor microenvironment. ECM, TGF-beta, TME
18  2020 Antitumor immunity targeting fibroblast activation protein-alpha in a mouse Lewis lung carcinoma model. DCs, FAP-alpha, LLC, rAd-c DCs, rAd-FAP-alpha
19  2020 Architecture of Cancer-Associated Fibroblasts in Tumor Microenvironment: Mapping Their Origins, Heterogeneity, and Role in Cancer Therapy Resistance. ECM, TME
20  2020 Biotechnological approach to induce human fibroblast apoptosis using superparamagnetic iron oxide nanoparticles. FITC, PI, SPIONs, SPION_Cit
21  2020 Blockade of Stromal Gas6 Alters Cancer Cell Plasticity, Activates NK Cells, and Inhibits Pancreatic Cancer Metastasis. EMT, Gas6, PDA, TAMs
22  2020 Breast Tumor Cell Invasion and Pro-Invasive Activity of Cancer-Associated Fibroblasts Co-Targeted by Novel Urokinase-Derived Decapeptides. alpha-SMA, TIF
23  2020 Broadening Drug Design and Targets to Tumor Microenvironment? Cancer-Associated Fibroblast Marker Expression in Cancers and Relevance for Survival Outcomes. FAP-alpha, PDGFRbeta, TME
24  2020 Bromodomain and Extraterminal (BET) protein inhibition suppresses tumor progression and inhibits HGF-MET signaling through targeting cancer-associated fibroblasts in colorectal cancer. BET, CRC
25  2020 CAF secreted miR-522 suppresses ferroptosis and promotes acquired chemo-resistance in gastric cancer. ALOX15, GC, hnRNP A1, lipid-ROS, USP7
26  2020 CAF-induced placental growth factor facilitates neoangiogenesis in hepatocellular carcinoma. HCC, HSCs, PlGF
27  2020 CAFs-derived MFAP5 promotes bladder cancer malignant behavior through NOTCH2/HEY1 signaling. EMSA, MFAP5
28  2020 Cancer associated fibroblast FAK regulates malignant cell metabolism. ---
29  2020 Cancer associated fibroblast mediated chemoresistance: A paradigm shift in understanding the mechanism of tumor progression. TME
30  2020 Cancer Associated Fibroblasts and Senescent Thyroid Cells in the Invasive Front of Thyroid Carcinoma. GEO, LOX, TC
31  2020 Cancer associated fibroblasts as novel promising therapeutic targets in breast cancer. ---
32  2020 Cancer associated fibroblasts confer shear resistance to circulating tumor cells during prostate cancer metastatic progression. alpha-SMA, FAP, FSS, NF, PC
33  2020 Cancer associated fibroblasts-derived exosomes contribute to radioresistance through promoting colorectal cancer stem cells phenotype. CRC, CSCs, TGF-beta
34  2020 Cancer associated fibroblasts: phenotypic and functional heterogeneity. TME
35  2020 Cancer associated fibroblasts: role in breast cancer and potential as therapeutic targets. ---
36  2020 Cancer cell niche factors secreted from cancer-associated fibroblast by loss of H3K27me3. NCAFs
37  2020 Cancer cells with high-metastatic potential promote a glycolytic shift in activated fibroblasts. GC
38  2020 Cancer-Associated Fibroblast Mediated Inhibition of CD8+ Cytotoxic T Cell Accumulation in Tumours: Mechanisms and Therapeutic Opportunities. ECM, TME
39  2020 Cancer-associated fibroblast-derived WNT2 increases tumor angiogenesis in colon cancer. CRC, ECs
40  2020 Cancer-associated fibroblasts downregulate type I interferon receptor to stimulate intratumoral stromagenesis. ECM, FAP, TGF-beta
41  2020 Cancer-associated fibroblasts enhance the chemoresistance of CD73+ hepatocellular carcinoma cancer cells via HGF-Met-ERK1/2 pathway. alpha-SMA, ELISA, HCC, HGF, RT-PCR
42  2020 Cancer-associated fibroblasts in desmoplastic tumors: emerging role of integrins. ECM, TME
43  2020 Cancer-Associated Fibroblasts in Mycosis Fungoides Promote Tumor Cell Migration and Drug Resistance via CXCL12/CXCR4. MF
44  2020 Cancer-associated fibroblasts in therapeutic resistance of pancreatic cancer: Present situation, predicaments, and perspectives. ---
45  2020 Cancer-associated fibroblasts induce epithelial-mesenchymal transition and cisplatin resistance in ovarian cancer via CXCL12/CXCR4 axis. EMT, EOC
46  2020 Cancer-associated Fibroblasts induce epithelial-mesenchymal transition via the Transglutaminase 2-dependent IL-6/IL6R/STAT3 axis in Hepatocellular Carcinoma. EMT, H-CAFs, HCC
47  2020 Cancer-associated fibroblasts mediate cancer progression and remodel the tumouroid stroma. FBLN5, HGF, VE-cadherin, VEGF-A
48  2020 Cancer-associated fibroblasts of the prostate promote a compliant and more invasive phenotype in benign prostate epithelial cells. AFM, NPFs, RT-FDC
49  2020 Cancer-associated fibroblasts promote cell growth by activating ERK5/PD-L1 signaling axis in colorectal cancer. CRC, PD-L1
50  2020 Cancer-associated fibroblasts promote cell proliferation and invasion via paracrine Wnt/IL1beta signaling pathway in human bladder cancer. BC, CM-CAF, NFs
51  2020 Cancer-associated fibroblasts promote hepatocellular carcinoma progression through downregulation of exosomal miR-150-3p. HCC, miRNAs, NFs, TME
52  2020 Cancer-associated fibroblasts promote malignancy of gastric cancer cells via Nodal signalling. DOX, GC
53  2020 Cancer-associated fibroblasts promote prostate tumor growth and progression through upregulation of cholesterol and steroid biosynthesis. AKR1C3, HMGCS2, PCa
54  2020 Cancer-associated fibroblasts promote the migration and invasion of gastric cancer cells via activating IL-17a/JAK2/STAT3 signaling. alpha-SMA, DFS, DSS, GC, IL-17a
55  2020 Cancer-Associated Fibroblasts Provide a Stromal Niche for Liver Cancer Organoids That Confers Trophic Effects and Therapy Resistance. ---
56  2020 Cancer-associated fibroblasts stimulate primary tumor growth and metastatic spread in an orthotopic prostate cancer xenograft model. BPHFs, NCAFs, PCa
57  2020 Cancer-associated fibroblasts, matrix metalloproteinase-9 and lymphatic vessel density are associated with progression from adenocarcinoma in situ to invasive adenocarcinoma of the lung. AIS, IAC, LVD, MMP-9, OS
58  2020 Cancer-associated fibroblasts-derived exosomal miR-17-5p promotes colorectal cancer aggressive phenotype by initiating a RUNX3/MYC/TGF-beta1 positive feedback loop. CRC, MYC, NFs, RUNX3, TGF-beta1, TME, UTRs
59  2020 Cancer-associated fibroblasts-derived exosomes-mediated transfer of LINC00355 regulates bladder cancer cell proliferation and invasion. alpha-SMA, BC, FAP, NFs, qRT-PCR
60  2020 Cancer-associated fibroblasts-derived gamma-glutamyltransferase 5 promotes tumor growth and drug resistance in lung adenocarcinoma. GGT5
61  2020 Cancer-associated fibroblasts-derived VCAM1 induced by H. pylori infection facilitates tumor invasion in gastric cancer. BLI, NAFs, VCAM1, zCDX
62  2020 Cancer-associated fibroblasts: activin A adds another string to their bow. NMSC
63  2020 Cancer-associated fibroblasts: key determinants of tumor immunity and immunotherapy. TME
64  2020 Cancer-Associated Fibroblasts: Versatile Players in the Tumor Microenvironment. FDA
65  2020 CCBE1 promotes tumor lymphangiogenesis and is negatively regulated by TGFbeta signaling in colorectal cancer. CCBE1, CRC, HLECs, TGF-beta, VEGF-C
66  2020 CD38 in cancer-associated fibroblasts promotes pro-tumoral activity. ---
67  2020 CD66b+ neutrophils and alpha-SMA+ fibroblasts predict clinical outcomes and benefits from postoperative chemotherapy in gastric adenocarcinoma. alpha-SMA, GAC, HR, TANs, TME
68  2020 CD73 on cancer-associated fibroblasts enhanced by the A2B-mediated feedforward circuit enforces an immune checkpoint. ADO, CRCs, NT5E
69  2020 Characterization of Pancreatic and Biliary Cancer Stem Cells in Patient-derived Tissue. CSCs, ECC, FACS, PDAC
70  2020 Chemotherapy resistance and stromal targets in breast cancer treatment: a review. IGS
71  2020 Chemotherapy-induced release of circulating-tumor cells into the bloodstream in collective migration units with cancer-associated fibroblasts in metastatic cancer patients. CTC, Met-pa
72  2020 Cinnamaldehyde induces endogenous apoptosis of the prostate cancer-associated fibroblasts via interfering the Glutathione-associated mitochondria function. CA, MDSCs, ROS
73  2020 Cinnamaldehyde Treatment of Prostate Cancer-Associated Fibroblasts Prevents Their Inhibitory Effect on T Cells Through Toll-Like Receptor 4. ---
74  2020 Clinical and functional significance of tumor/stromal ATR expression in breast cancer patients. ---
75  2020 Collective Cancer Cell Invasion in Contact with Fibroblasts via Integrin-alpha5beta1/Fibronectin Interaction in Collagen Matrix. ---
76  2020 Conditioned medium of the osteosarcoma cell line U2OS induces hBMSCs to exhibit characteristics of carcinoma-associated fibroblasts via activation of IL-6/STAT3 signalling. BMSCs, hBMSCs, OS, U2OS
77  2020 Connective tissue growth factor produced by cancer‑associated fibroblasts correlates with poor prognosis in epithelioid malignant pleural mesothelioma. alpha-SMA, CTGF
78  2020 Core-shell nanoparticles suppress metastasis and modify the tumour-supportive activity of cancer-associated fibroblasts. ---
79  2020 Crosstalk between cancer-associated fibroblasts and immune cells in cancer. ---
80  2020 Crosstalk between Tumor and Stromal Cells in Pancreatic Ductal Adenocarcinoma. ECM, PDAC, TME
81  2020 CTL Attenuation Regulated by PS1 in Cancer-Associated Fibroblast. CTLs, IL, PS1, TME
82  2020 Curcumin promotes cancer-associated fibroblasts apoptosis via ROS-mediated endoplasmic reticulum stress. DeltaPsim
83  2020 Curcumin suppresses the proliferation and tumorigenicity of Cal27 by modulating cancer associated fibroblasts of TSCC. CM, MMP2, PTFs, SDF-1, TGF-beta1, TME
84  2020 CXCR2 signaling promotes secretory cancer-associated fibroblasts in pancreatic ductal adenocarcinoma. CXCR2, PDAC
85  2020 CXCR4/TGF-beta1 mediated hepatic stellate cells differentiation into carcinoma-associated fibroblasts and promoted liver metastasis of colon cancer. CRC, CY, HSCs, TME
86  2020 CXCR4/TGF-beta1 mediated self-differentiation of human mesenchymal stem cells to carcinoma-associated fibroblasts and promoted colorectal carcinoma development. CRC, CY, MSCs, SDF-1, TGF-beta1, TME
87  2020 Dangerous Liaisons: Circulating Tumor Cells (CTCs) and Cancer-Associated Fibroblasts (CAFs). CTCs, TME
88  2020 Deficiency in fibroblast PPARbeta/delta reduces nonmelanoma skin cancers in mice. NMSC
89  2020 Deficiency of the adrenomedullin-RAMP3 system suppresses metastasis through the modification of cancer-associated fibroblasts. AM, PDPN, RAMPs
90  2020 Deregulation of miR-27a may contribute to canine fibroblast activation after coculture with a mast cell tumour cell line. CCNG1, IL-6, miRNAs
91  2020 Design and validation of fibroblast activation protein alpha targeted imaging and therapeutic agents. FAP, FL
92  2020 Diminished CD68+ Cancer-Associated Fibroblast Subset Induces Regulatory T-Cell (Treg) Infiltration and Predicts Poor Prognosis of Oral Squamous Cell Carcinoma Patients. OSCC
93  2020 Distinct fibroblast functional states drive clinical outcomes in ovarian cancer and are regulated by TCF21. FAP
94  2020 Disulfiram/Copper Induces Antitumor Activity against Both Nasopharyngeal Cancer Cells and Cancer-Associated Fibroblasts through ROS/MAPK and Ferroptosis Pathways. ALDH, alpha-SMA, FACS, IHC, NAC, NPC
95  2020 Doxorubicin pretreatment enhances FAPalpha/survivin co-targeting DNA vaccine anti-tumor activity primarily through decreasing peripheral MDSCs in the 4T1 murine breast cancer model. DOX, FAPalpha, MDSCs, TME
96  2020 Dual Inhibitory Action of a Novel AKR1C3 Inhibitor on Both Full-Length AR and the Variant AR-V7 in Enzalutamide Resistant Metastatic Castration Resistant Prostate Cancer. AR, PSA
97  2020 Ectonucleotidase CD73 and CD39 expression in non-small cell lung cancer relates to hypoxia and immunosuppressive pathways. ATP, NSCLC, TILs
98  2020 Effects of pirfenidone targeting the tumor microenvironment and tumor-stroma interaction as a novel treatment for non-small cell lung cancer. CM, EMT, NSCLC, PFD
99  2020 Efficient Isolation, Culture, Purification and Stem Cell Expression Profiles of Primary Tumor Cells Derived from Uterine Cervical Squamous Cell Carcinoma. ALDH1, CSCC, CSCs, EpCAM, FCM, PDL1
100  2020 Emerging Nano Drug Delivery Systems Targeting Cancer-Associated Fibroblasts for Improved Antitumor Effect and Tumor Drug Penetration. IFP