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[Related PubMed/MEDLINE]
Total Number of Papers: 243
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| Abbreviation |
: CAVD |
| Long Form |
: Calcific aortic valve disease |
|
| No. |
Year |
Title |
Co-occurring Abbreviation |
| 1 |
2020 |
AGEs-RAGE axis causes endothelial-to-mesenchymal transition in early calcific aortic valve disease via TGF-beta1 and BMPR2 signaling. |
AGEs, ALP, alpha-SMA, EndMT, TGF-beta1, VE-cadherin |
| 2 |
2020 |
Aldo-keto reductase family 1 member B induces aortic valve calcification by activating hippo signaling in valvular interstitial cells. |
Akr1B1, RNA-Seq |
| 3 |
2020 |
AntagomiR-29b inhibits vascular and valvular calcification and improves heart function in rats. |
ALP |
| 4 |
2020 |
Antibody microarray analysis of serum inflammatory cytokines in patients with calcific aortic valve disease. |
BLC, CAD, IL, MIG, MIP |
| 5 |
2020 |
Bench to bedside defining calcific aortic valve disease: osteocardiology. |
--- |
| 6 |
2020 |
Caffeic Acid Phenethyl Ester Ameliorates Calcification by Inhibiting Activation of the AKT/NF-kappaB/NLRP3 Inflammasome Pathway in Human Aortic Valve Interstitial Cells. |
AVICs, CAPE, DEGs, OM |
| 7 |
2020 |
Calcific Aortic Valve Disease-Natural History and Future Therapeutic Strategies. |
--- |
| 8 |
2020 |
Celastrol Alleviates Aortic Valve Calcification Via Inhibition of NADPH Oxidase 2 in Valvular Interstitial Cells. |
AVICs, NOX2, ROS |
| 9 |
2020 |
Cell-Type Transcriptome Atlas of Human Aortic Valves Reveal Cell Heterogeneity and Endothelial to Mesenchymal Transition Involved in Calcific Aortic Valve Disease. |
--- |
| 10 |
2020 |
CircRNA TGFBR2/MiR-25-3p/TWIST1 axis regulates osteoblast differentiation of human aortic valve interstitial cells. |
ALP, VICs |
| 11 |
2020 |
Correlations between lipoprotein(a) gene polymorphisms and calcific aortic valve disease and coronary heart disease in Han Chinese. |
CHD, LPA |
| 12 |
2020 |
Curcumin inhibits calcification of human aortic valve interstitial cells by interfering NF-kappaB, AKT, and ERK pathways. |
CCM, hVICs, OM |
| 13 |
2020 |
Endothelial-to-Mesenchymal Transition in Calcific Aortic Valve Disease. |
EndMT, VECs |
| 14 |
2020 |
Global, Regional, and National Burden of Calcific Aortic Valve and Degenerative Mitral Valve Diseases, 1990-2017. |
DALYs, DMVD, GBD, NRVDs, UI |
| 15 |
2020 |
Identification of a peripheral blood gene signature predicting aortic valve calcification. |
--- |
| 16 |
2020 |
Identification of key genes in calcific aortic valve disease by integrated bioinformatics analysis. |
DEGs, ECM, MCC, PPI |
| 17 |
2020 |
Inhibition of PP2A enhances the osteogenic differentiation of human aortic valvular interstitial cells via ERK and p38 MAPK pathways. |
RT-PCR, VICs |
| 18 |
2020 |
Inorganic phosphate-osteogenic induction medium promotes osteogenic differentiation of valvular interstitial cells via the BMP-2/Smad1/5/9 and RhoA/ROCK-1 signaling pathways. |
IP-OIM, OIM, VICs |
| 19 |
2020 |
Integrative Multi-Omics Analysis in Calcific Aortic Valve Disease Reveals a Link to the Formation of Amyloid-Like Deposits. |
A2M, ApoA1, APP, HBB, IGKC, ITIH3, LBP, miRNA, SERPINA1, Tf, TGFBI, TTR |
| 20 |
2020 |
Interleukin 37 Suppresses M1 Macrophage Polarization Through Inhibition of the Notch1 and Nuclear Factor Kappa B Pathways. |
IFN-gamma, IL-37, iNOS, LPS, MCP-1, NF-kappaB, PMA |
| 21 |
2020 |
Label-free metabolic biomarkers for assessing valve interstitial cell calcific progression. |
TPEF, VICs |
| 22 |
2020 |
Lipoprotein(a): Expanding Our Knowledge of Aortic Valve Narrowing. |
AS, ASCVD |
| 23 |
2020 |
Mechanistic Roles of Matrilin-2 and Klotho in Modulating the Inflammatory Activity of Human Aortic Valve Cells. |
AVICs, ECM, PKR, TLR |
| 24 |
2020 |
Melatonin ameliorates aortic valve calcification via the regulation of circular RNA CircRIC3/miR-204-5p/DPP4 signaling in valvular interstitial cells. |
DPP4, HCD |
| 25 |
2020 |
MicroRNA-34c Inhibits Osteogenic Differentiation and Valvular Interstitial Cell Calcification via STC1-Mediated JNK Pathway in Calcific Aortic Valve Disease. |
ALP, BMP2, JNK, VICs |
| 26 |
2020 |
Molecular mechanisms involved in high glucose-induced valve calcification in a 3D valve model with human valvular cells. |
BMP, ECM, HG, MMPs, NG, VEC, VIC |
| 27 |
2020 |
Monocytes enhance the inflammatory response to TLR2 stimulation in aortic valve interstitial cells through paracrine up-regulation of TLR2 level. |
AVICs, TLRs |
| 28 |
2020 |
Nano-Polyplexes Mediated Transfection of Runx2-shRNA Mitigates the Osteodifferentiation of Human Valvular Interstitial Cells. |
sh, VIC |
| 29 |
2020 |
NFkappaB (Nuclear Factor kappa-Light-Chain Enhancer of Activated B Cells) Activity Regulates Cell-Type-Specific and Context-Specific Susceptibility to Calcification in the Aortic Valve. |
--- |
| 30 |
2020 |
Nucleotide ecto-enzyme metabolic pattern and spatial distribution in calcific aortic valve disease; its relation to pathological changes and clinical presentation. |
--- |
| 31 |
2020 |
Plasma lipoprotein(a) concentration as an independent predictor of hemodynamic progression of aortic valve stenosis. |
--- |
| 32 |
2020 |
Potential role of full-length and nonfull-length progranulin in affecting aortic valve calcification. |
AV, hVICs, OM, PGRN, pVICs, WT |
| 33 |
2020 |
Quantifying Apolipoprotein(a) in the era of Proteoforms and Precision Medicine. |
ASCVD |
| 34 |
2020 |
Sex-differences in echocardiographic assessment of aortic valve in young adult LDLr-/-/ApoB100/100/IGF-II+/- mice. |
--- |
| 35 |
2020 |
Sex-Specific Features of Calcific Aortic Valve Disease. |
AS |
| 36 |
2020 |
Statin treatment of patients with calcific aortic valve disease modulates extracellular adenosine metabolism on the cell surface of the aortic valve. |
E-ADA |
| 37 |
2020 |
The dedicated "Lp(a) clinic": A concept whose time has arrived? |
CVD |
| 38 |
2020 |
The impact of altered mechanobiology on aortic valve pathophysiology. |
--- |
| 39 |
2020 |
The natural compound andrographolide inhibits human aortic valve interstitial cell calcification via the NF-kappa B/Akt/ERK pathway. |
AGP, DEGs, hVICs, OM, VICs |
| 40 |
2020 |
The role of stress concentration in calcified bicuspid aortic valve. |
ATC, BAV, FE |
| 41 |
2020 |
The Ryanodine Receptor Contributes to the Lysophosphatidylcholine-Induced Mineralization in Valvular Interstitial Cells. |
VICs |
| 42 |
2020 |
TLR4 Stimulation Promotes Human AVIC Fibrogenic Activity through Upregulation of Neurotrophin 3 Production. |
AVIC, ECM, MMP-9, NT-3, Trk |
| 43 |
2020 |
Transforming growth factor-beta1 promotes fibrosis but attenuates calcification of valvular tissue applied as three-dimensional calcific aortic valve disease model. |
VICs |
| 44 |
2020 |
Ultrastructural Pathology of Atherosclerosis, Calcific Aortic Valve Disease, and Bioprosthetic Heart Valve Degeneration: Commonalities and Differences. |
ECM |
| 45 |
2020 |
Upregulation of microRNA-195 ameliorates calcific aortic valve disease by inhibiting VWF via suppression of the p38-MAPK signaling pathway. |
AVICs, DEGs, miRNAs |
| 46 |
2019 |
Activation of the calcium-sensing receptor in human valvular interstitial cells promotes calcification. |
CaSR, hVICs |
| 47 |
2019 |
Adaptive immune cells in calcific aortic valve disease. |
--- |
| 48 |
2019 |
Association Between Serum Leptin Level and Calcific Aortic Valve Disease. |
--- |
| 49 |
2019 |
Autotaxin and Lipoprotein Metabolism in Calcific Aortic Valve Disease. |
ATX, GWA, lysoPA, MR, OxPLs, PLPP3, VICs |
| 50 |
2019 |
Biomechanical modeling of transcatheter aortic valve replacement in a stenotic bicuspid aortic valve: deployments and paravalvular leakage. |
BAV, PVL, TAVR |
| 51 |
2019 |
Calcification and extracellular matrix dysregulation in human postmortem and surgical aortic valves. |
AoV, AS, ECM |
| 52 |
2019 |
Cardiovascular Effects and Molecular Mechanisms of Bisphenol A and Its Metabolite MBP in Zebrafish. |
BPA, ECM, ERE |
| 53 |
2019 |
CC chemokine receptor 2 functions in osteoblastic transformation of valvular interstitial cells. |
AVICs, CCRs |
| 54 |
2019 |
Characterizing valve dynamics in mice by high-resolution cine-MRI. |
EF, WD |
| 55 |
2019 |
Development of calcific aortic valve disease: Do we know enough for new clinical trials? |
VECM, VICs |
| 56 |
2019 |
Elastin-Dependent Aortic Heart Valve Leaflet Curvature Changes During Cyclic Flexure. |
ECM |
| 57 |
2019 |
Genetic variants in cardiac calcification in Northern Sweden. |
ABCC6, CCAD, NT5E, Pi |
| 58 |
2019 |
H19 is not hypomethylated or upregulated with age or sex in the aortic valves of mice. |
--- |
| 59 |
2019 |
Heat shock protein 90 is downregulated in calcific aortic valve disease. |
ANXA2, IPA, PDIA3 |
| 60 |
2019 |
Heterogeneous multi-laminar tissue constructs as a platform to evaluate aortic valve matrix-dependent pathogenicity. |
VICs |
| 61 |
2019 |
Hyperphosphatemia is required for initiation but not propagation of kidney failure-induced calcific aortic valve disease. |
--- |
| 62 |
2019 |
Identification of key genes and pathways in calcific aortic valve disease by bioinformatics analysis. |
CAMs, DEGs, GEO, GO, PPI |
| 63 |
2019 |
Increased mesenchymal podoplanin expression is associated with calcification in aortic valves. |
AS, RT-PCR |
| 64 |
2019 |
Knockdown of CD44 expression decreases valve interstitial cell calcification in vitro. |
ECM, HA, PAAm, RHAMM, VICs |
| 65 |
2019 |
Lipopolysaccharide and interferon-gamma team up to activate HIF-1alpha via STAT1 in normoxia and exhibit sex differences in human aortic valve interstitial cells. |
AVICs, HIF, IFN, JAK, LPS, STAT, TLR |
| 66 |
2019 |
Lipoprotein(a) Gene Polymorphism Increases a Risk Factor for Aortic Valve Calcification. |
--- |
| 67 |
2019 |
LncRNA OIP5-AS1 inhibits osteoblast differentiation of valve interstitial cells via miR-137/TWIST11 axis. |
lncRNA, qRT-PCR, RIP, TWIST1, VICs |
| 68 |
2019 |
Meis2 represses the osteoblastic transdifferentiation of aortic valve interstitial cells through the Notch1/Twist1 pathway. |
EMT, NCCs, VICs |
| 69 |
2019 |
MicroRNA-204 Deficiency in Human Aortic Valves Elevates Valvular Osteogenic Activity. |
ALP, AVICs, miR-204 |
| 70 |
2019 |
MicroRNA-214 promotes the calcification of human aortic valve interstitial cells through the acceleration of inflammatory reactions with activated MyD88/NF-kappaB signaling. |
AVICs, ELISA, LPS, miRs |
| 71 |
2019 |
MicroRNA-638 inhibits human aortic valve interstitial cell calcification by targeting Sp7. |
HAVICs, SP7 |
| 72 |
2019 |
MMP-12-Induced Pro-osteogenic Responses in Human Aortic Valve Interstitial Cells. |
ALP, AVICs, BMP-2, LRP-6, MAPK, MMP-12 |
| 73 |
2019 |
Native aortic valve derived extracellular matrix hydrogel for three dimensional culture analyses with improved biomimetic properties. |
AVdH, ECM |
| 74 |
2019 |
New Frontiers in Lp(a)-Targeted Therapies. |
ASCVD |
| 75 |
2019 |
Oxidized HDL, as a Novel Biomarker for Calcific Aortic Valve Disease, Promotes the Calcification of Aortic Valve Interstitial Cells. |
ALP, AVICs, CAD, oxHDL |
| 76 |
2019 |
Oxidized phospholipids as a unifying theory for lipoprotein(a) and cardiovascular disease. |
ASCVD |
| 77 |
2019 |
Predictive Roles of Neutrophil-to-Lymphocyte Ratio and C-Reactive Protein in Patients with Calcific Aortic Valve Disease. |
AVR, CPB, CRP, NLR |
| 78 |
2019 |
Spatiotemporal Complexity of the Aortic Sinus Vortex as a Function of Leaflet Calcification. |
--- |
| 79 |
2019 |
Standardization of Human Calcific Aortic Valve Disease in vitro Modeling Reveals Passage-Dependent Calcification. |
OM, PM, TNAP, VICs |
| 80 |
2019 |
The methylation of Notch1 promoter mediates the osteogenesis differentiation in human aortic valve interstitial cells through Wnt/beta-catenin signaling. |
AVICs, hAVICs, PCR |
| 81 |
2018 |
A New Growth Model for Aortic Valve Calcification. |
CT, RCT |
| 82 |
2018 |
Advances in Pathophysiology of Calcific Aortic Valve Disease Propose Novel Molecular Therapeutic Targets. |
--- |
| 83 |
2018 |
Association between homocysteine levels and calcific aortic valve disease: a systematic review and meta-analysis. |
Hcy, SMD |
| 84 |
2018 |
Calcific Aortic Valve Disease: a Developmental Biology Perspective. |
BMP, TGF-beta |
| 85 |
2018 |
CD39 and CD73 in the aortic valve-biochemical and immunohistochemical analysis in valve cell populations and its changes in valve mineralization. |
--- |
| 86 |
2018 |
Comparing the Role of Mechanical Forces in Vascular and Valvular Calcification Progression. |
ECM |
| 87 |
2018 |
Creation of disease-inspired biomaterial environments to mimic pathological events in early calcific aortic valve disease. |
CS, GAG, HA, oxLDL, VEGF, VICs |
| 88 |
2018 |
Crystallinity of hydroxyapatite drives myofibroblastic activation and calcification in aortic valves. |
HA |
| 89 |
2018 |
Deletion of calponin 2 attenuates the development of calcific aortic valve disease in ApoE-/- mice. |
KO, SMA, WT |
| 90 |
2018 |
DNA methylation of a PLPP3 MIR transposon-based enhancer promotes an osteogenic programme in calcific aortic valve disease. |
5-MeC, AV, dCas9-DNMT, lysoPA, MIR, PLPPs, VICs |
| 91 |
2018 |
Engineering a 3D-Bioprinted Model of Human Heart Valve Disease Using Nanoindentation-Based Biomechanics. |
AV, OM, VICs |
| 92 |
2018 |
Exploiting novel valve interstitial cell lines to study calcific aortic valve disease. |
MGP, VICs |
| 93 |
2018 |
In-vitro analysis of early calcification in aortic valvular interstitial cells using Laser-Induced Breakdown Spectroscopy (LIBS). |
LIBS, VICs |
| 94 |
2018 |
Increased Calcific Aortic Valve Disease in response to a diabetogenic, procalcific diet in the LDLr-/-ApoB100/100 mouse model. |
AS, DB diet, NC, VIC |
| 95 |
2018 |
Inflammatory and metabolic mechanisms underlying the calcific aortic valve disease. |
--- |
| 96 |
2018 |
Involvement of inflammatory responses in the early development of calcific aortic valve disease: lessons from statin therapy. |
--- |
| 97 |
2018 |
LncRNA TUG1 sponges miR-204-5p to promote osteoblast differentiation through upregulating Runx2 in aortic valve calcification. |
lncRNAs, shRNA, VICs |
| 98 |
2018 |
Mechanosensitive microRNA-181b Regulates Aortic Valve Endothelial Matrix Degradation by Targeting TIMP3. |
ECM, HAVECs |
| 99 |
2018 |
Metformin ameliorates TGF-beta1-induced osteoblastic differentiation of human aortic valve interstitial cells by inhibiting beta-catenin signaling. |
AVICs |
| 100 |
2018 |
Molecular imaging of calcific aortic valve disease. |
FDG |
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