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Abbreviation : CDO
Long Form : cysteine dioxygenase
No. Year Title Co-occurring Abbreviation
2019 A Structural and Functional Model for the Tris-Histidine Motif in Cysteine Dioxygenase. ---
2019 Alteration of dietary cysteine affects activities of genes of the transsulfuration and glutathione pathways, and development of skin tissues and feather follicles in chickens. CBS, CTL, GSS
2019 Cysteine Dioxygenase Regulates the Epithelial Morphogenesis of Mammary Gland via Cysteine Sulfinic Acid. CSA, KO
2019 Functional analysis of active amino acid residues of the mercaptosuccinate dioxygenase of Variovorax paradoxus B4. MS, Msdo
2019 Probing the Cys-Tyr Cofactor Biogenesis in Cysteine Dioxygenase by the Genetic Incorporation of Fluorotyrosine. ---
2018 A synthetic model of the nonheme iron-superoxo intermediate of cysteine dioxygenase. ---
2018 Cleavage of a carbon-fluorine bond by an engineered cysteine dioxygenase. ---
2018 Cysteine dioxygenase is essential for mouse sperm osmoadaptation and male fertility. ---
2018 Spectroscopic and Electronic Structure Study of ETHE1: Elucidating the Factors Influencing Sulfur Oxidation and Oxygenation in Mononuclear Nonheme Iron Enzymes. IPNS
10  2017 Antioxidant Effect of Barley Sprout Extract via Enhancement of Nuclear Factor-Erythroid 2 Related Factor 2 Activity and Glutathione Synthesis. 4-HNE, BSE, GCLC, HO-1, MDA, NQO1, Nrf2
11  2017 On the Dynamical Behavior of the Cysteine Dioxygenase-l-Cysteine Complex in the Presence of Free Dioxygen and l-Cysteine. MD, RAMD
12  2017 Spectroscopic and computational studies of reversible O2 binding by a cobalt complex of relevance to cysteine dioxygenase. EPR
13  2017 Taurine Biosynthesis in a Fish Liver Cell Line (ZFL) Adapted to a Serum-Free Medium. CSAD, ZFL
14  2017 Understanding human thiol dioxygenase enzymes: structure to function, and biology to pathology. Ado, Cys
15  2016 Differential regulation of taurine biosynthesis in rainbow trout and Japanese flounder. CSD
16  2016 Effects of a block in cysteine catabolism on energy balance and fat metabolism in mice. SCD1
17  2016 Heterogeneous behavior of metalloproteins toward metal ion binding and selectivity: insights from molecular dynamics studies. MD
18  2016 Non-chemical proton-dependent steps prior to O2-activation limit Azotobacter vinelandii 3-mercaptopropionic acid dioxygenase (MDO) catalysis. 3-MPA, 3spa, cys, MDO
19  2016 Structure-Based Insights into the Role of the Cys-Tyr Crosslink and Inhibitor Recognition by Mammalian Cysteine Dioxygenase. Hcy
20  2016 Synthesis, X-ray Structures, Electronic Properties, and O2/NO Reactivities of Thiol Dioxygenase Active-Site Models. CysAm, DFT, DNICs, EPR, IR, MCD, NO, TDOs
21  2015 Estradiol decreases taurine level by reducing cysteine sulfinic acid decarboxylase via the estrogen receptor-alpha in female mice liver. CSAD, ERalpha, ERbeta
22  2015 Involvement of the Cys-Tyr cofactor on iron binding in the active site of human cysteine dioxygenase. ---
23  2015 Ontogenetic taurine biosynthesis ability in rainbow trout (Oncorhynchus mykiss). CSD
24  2015 Spectroscopic and Computational Investigation of the H155A Variant of Cysteine Dioxygenase: Geometric and Electronic Consequences of a Third-Sphere Amino Acid Substitution. Cys, WT
25  2015 Steady-state substrate specificity and O₂-coupling efficiency of mouse cysteine dioxygenase. CSA, Cys
26  2015 Structures of Arg- and Gln-type bacterial cysteine dioxygenase homologs. BsCDO, ReCDOhom
27  2015 The "Gln-Type" Thiol Dioxygenase from Azotobacter vinelandii is a 3-Mercaptopropionic Acid Dioxygenase. Av, CA, cys, EPR, NO
28  2015 Utilizing the Trispyrazolyl Borate Ligand for the Mimicking of O2-Activating Mononuclear Nonheme Iron Enzymes. ACCO, Tp
29  2014 Altered hepatic sulfur metabolism in cystathionine beta-synthase-deficient homocystinuria: regulatory role of taurine on competing cysteine oxidation pathways. CSAD, HCU
30  2014 Branched-chain amino acids inhibit the TGF-beta-induced down-regulation of taurine biosynthetic enzyme cysteine dioxygenase in HepG2 cells. BCAA, TGF-beta
31  2014 Exposition of dermatophyte Trichophyton mentagrophytes to L-cystine induces expression and activation of cysteine dioxygenase. ---
32  2014 Oxidative uncoupling in cysteine dioxygenase is gated by a proton-sensitive intermediate. CSA, Cys
33  2014 Primary hepatocytes from mice lacking cysteine dioxygenase show increased cysteine concentrations and higher rates of metabolism of cysteine to hydrogen sulfide and thiosulfate. CBS, CTH
34  2014 Shifting redox states of the iron center partitions CDO between crosslink formation or cysteine oxidation. ---
35  2014 Spectroscopic and computational investigation of iron(III) cysteine dioxygenase: implications for the nature of the putative superoxo-Fe(III) intermediate. Cys, DFT
36  2014 The Cys-Tyr cross-link of cysteine dioxygenase changes the optimal pH of the reaction without a structural change. ---
37  2013 Cysteine dioxygenase structures from pH4 to 9: consistent cys-persulfenate formation at intermediate pH and a Cys-bound enzyme at higher pH. Cys
38  2013 Imposing function down a (cupin)-barrel: secondary structure and metal stereochemistry in the alphaKG-dependent oxygenases. alpha-KG, IPNS
39  2013 Metal vs. chalcogen competition in the catalytic mechanism of cysteine dioxygenase. Cys, Sec
40  2013 Second-sphere interactions between the C93-Y157 cross-link and the substrate-bound Fe site influence the O₂ coupling efficiency in mouse cysteine dioxygenase. CSA, EPR, l-Cys
41  2013 Spectroscopic and computational characterization of the NO adduct of substrate-bound Fe(II) cysteine dioxygenase: insights into the mechanism of O2 activation. Cys, Sec
42  2013 The cysteine dioxgenase knockout mouse: altered cysteine metabolism in nonhepatic tissues leads to excess H2S/HS(-) production and evidence of pancreatic and lung toxicity. CBS
43  2012 A chromium(III)-superoxo complex in oxygen atom transfer reactions as a chemical model of cysteine dioxygenase. OAT
44  2012 A strongly bound high-spin iron(II) coordinates cysteine and homocysteine in cysteine dioxygenase. ---
45  2012 Addition of an external electron donor to in vitro assays of cysteine dioxygenase precludes the need for exogenous iron. ---
46  2012 Addition of dioxygen to an N4S(thiolate) iron(II) cysteine dioxygenase model gives a structurally characterized sulfinato-iron(II) complex. ---
47  2012 Extrahepatic tissues compensate for loss of hepatic taurine synthesis in mice with liver-specific knockout of cysteine dioxygenase. ---
48  2011 Correlating crosslink formation with enzymatic activity in cysteine dioxygenase. ---
49  2011 Endogenous generation of sulfur dioxide in rat tissues. AAT
50  2011 Knockout of the murine cysteine dioxygenase gene results in severe impairment in ability to synthesize taurine and an increased catabolism of cysteine to hydrogen sulfide. ---
51  2011 O2 activation by bis(imino)pyridine iron(II)-thiolate complexes. ---
52  2011 Single turnover of substrate-bound ferric cysteine dioxygenase with superoxide anion: enzymatic reactivation, product formation, and a transient intermediate. CSA, Cys
53  2011 Theoretical study on the mechanism of the oxygen activation process in cysteine dioxygenase enzymes. QM/MM
54  2011 Thiol dioxygenases: unique families of cupin proteins. ---
55  2010 Iron(II)-thiolate S-oxygenation by O2: synthetic models of cysteine dioxygenase. ---
56  2010 Spectroscopic and computational characterization of substrate-bound mouse cysteine dioxygenase: nature of the ferrous and ferric cysteine adducts and mechanistic implications. Sec
57  2010 The three-his triad in Dke1: comparisons to the classical facial triad. alpha-KG, CS2, HPPD
58  2009 3T3-L1 adipocytes and rat adipose tissue have a high capacity for taurine synthesis by the cysteine dioxygenase/cysteinesulfinate decarboxylase and cysteamine dioxygenase pathways. CSAD, LP
59  2009 Cysteine dioxygenase: a robust system for regulation of cellular cysteine levels. ---
60  2009 Mass-spectrometric characterization of two posttranslational modifications of cysteine dioxygenase. ---
61  2009 Why do cysteine dioxygenase enzymes contain a 3-His ligand motif rather than a 2His/1Asp motif like most nonheme dioxygenases? TauD
62  2008 A putative Fe2+-bound persulfenate intermediate in cysteine dioxygenase. ---
63  2008 Synthesis of amino acid cofactor in cysteine dioxygenase is regulated by substrate and represents a novel post-translational regulation of activity. ---
64  2007 Ablation of the mammalian methionine sulfoxide reductase A affects the expression level of cysteine deoxygenase. MsrA, Msrs
65  2007 Characterization of the nitrosyl adduct of substrate-bound mouse cysteine dioxygenase by electron paramagnetic resonance: electronic structure of the active site and mechanistic implications. 2H1C
66  2007 Cysteine dioxygenase: structure and mechanism. ---
67  2007 Discovery and characterization of a second mammalian thiol dioxygenase, cysteamine dioxygenase. ---
68  2007 Enzymes of the taurine biosynthetic pathway are expressed in rat mammary gland. CSAD
69  2007 Overexpression of cysteine dioxygenase reduces intracellular cysteine and glutathione pools in HepG2/C3A cells. WT
70  2006 Copper deficiency does not lead to taurine deficiency in rats. BW, CSAD
71  2006 Identification and characterization of bacterial cysteine dioxygenases: a new route of cysteine degradation for eubacteria. ---
72  2006 Mammalian cysteine metabolism: new insights into regulation of cysteine metabolism. GCL
73  2006 Probes of the catalytic site of cysteine dioxygenase. ---
74  2006 Structure and mechanism of mouse cysteine dioxygenase. ---
75  2006 Taurine (2-aminoethanesulfonic acid) deficiency creates a vicious circle promoting obesity. ---
76  2005 Preparation, crystallization and X-ray diffraction analysis to 1.5 A resolution of rat cysteine dioxygenase, a mononuclear iron enzyme responsible for cysteine thiol oxidation. ---
77  2004 Evidence for expression of a single distinct form of mammalian cysteine dioxygenase. ---
78  2004 Lack of congruence between cysteine dioxygenase activity and S-carboxymethyl-L-cysteine S-oxidation activity in rat cytosol. S-CMC
79  2004 Physiological significance of the taurine transporter and taurine biosynthetic enzymes in 3T3-L1 adipocytes. TAUT
80  2004 Regulation of cysteine dioxygenase and gamma-glutamylcysteine synthetase is associated with hepatic cysteine level. GCS, HP, LP
81  2004 Taurine biosynthetic enzymes and taurine transporter: molecular identification and regulations. CSD, TAUT
82  2004 The ubiquitin-proteasome system is responsible for cysteine-responsive regulation of cysteine dioxygenase concentration in liver. ---
83  2003 Cysteine is the metabolic signal responsible for dietary regulation of hepatic cysteine dioxygenase and glutamate cysteine ligase in intact rats. GCL
84  2003 Effect of acute ethanol administration on S-amino acid metabolism: increased utilization of cysteine for synthesis of taurine rather than glutathione. CbetaS, CgammaL, GCS, MAT, SAH, SAM
85  2003 Expression of cysteine dioxygenase (EC and sulfite oxidase in the human lung: a potential role for sulfate production in the protection from airborne xenobiotica. SO
86  2003 Functional characterization and regulation of the taurine transporter and cysteine dioxygenase in human hepatoblastoma HepG2 cells. TAUT
87  2003 Taurine: new implications for an old amino acid. TauCl
88  2002 Cysteine dioxygenase: modulation of expression in human cell lines by cytokines and control of sulphate production. TGF-beta, TNF-alpha
89  2002 Enzymes and metabolites of cysteine metabolism in nonhepatic tissues of rats show little response to changes in dietary protein or sulfur amino acid levels. CSD, GCS
90  2001 Cysteine dioxygenase: regional localisation of protein and mRNA in rat brain. ---
91  2001 Cysteine regulates expression of cysteine dioxygenase and gamma-glutamylcysteine synthetase in cultured rat hepatocytes. GCS, GCS-HS
92  2001 Gene expression of the taurine transporter and taurine biosynthetic enzymes in rat kidney after antidiuresis and salt loading. AR, CSD, OS, RT-PCR, SMIT, TAUT
93  2001 Murine cysteine dioxygenase gene: structural organization, tissue-specific expression and promoter identification. ---
94  2000 Cysteine dioxygenase and gamma-glutamylcysteine synthetase activities in primary cultured hepatocytes respond to sulfur amino acid supplementation in a reciprocal manner. CSDC, GCS
95  2000 Development of an in vitro model for cysteine dioxygenase expression in the brain. NPA
96  2000 Gene expression of taurine transporter and taurine biosynthetic enzymes in brain of rats with acute or chronic hyperosmotic plasma. A comparative study with gene expression of myo-inositol transporter, betaine transporter and sorbitol biosynthetic enzyme. AR, CSD, TAUT
97  2000 Gene expression of the transporters and biosynthetic enzymes of the osmolytes in astrocyte primary cultures exposed to hyperosmotic conditions. AR, CSD
98  2000 Post-transcriptional regulation of cysteine dioxygenase in rat liver. ---
99  2000 Taurine down-regulates basal and osmolarity-induced gene expression of its transporter, but not the gene expression of its biosynthetic enzymes, in astrocyte primary cultures. CSD, TAUT
100  1999 Effects of nonsulfur and sulfur amino acids on the regulation of hepatic enzymes of cysteine metabolism. aa, CSDC, GCS, SAA