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Abbreviation : CE
Long Form : carboxylesterase
No. Year Title Co-occurring Abbreviation
2019 Biochar increases pesticide-detoxifying carboxylesterases along earthworm burrows. ---
2019 Exploring the potential enzymatic bioremediation of vermicompost through pesticide-detoxifying carboxylesterases. MC, OP
2019 Preliminary results on the uptake and biochemical response to water-exposure of Tamiflu (oseltamivir phosphate) in two marine bivalves. 1-NA, 1NB, OST-C
2019 Ratiometric two-photon fluorescent probe for in situ imaging of carboxylesterase (CE)-mediated mitochondrial acidification during medication. ---
2018 Assessment of mouse strain differences in baseline esterase activities and toxic response to sarin. AChE, BChE, MLD, NA, s.c
2018 Multibiomarker biomonitoring approach using three bivalve species in the Ebro Delta (Catalonia, Spain). ---
2018 Potent, Irreversible Inhibition of Human Carboxylesterases by Tanshinone Anhydrides Isolated from Salvia miltiorrhiza ("Danshen"). ---
2018 Pyrethroid Acaricide Resistance Is Proportional to P-450 Cytochrome Oxidase Expression in the Cattle Tick Rhipicephalus microplus. AChE, CYP, OP, Pyr, REU, XMEs
2018 Viral infection induces different detoxification enzyme activities in insecticide-resistant and -susceptible brown planthopper Nilaparvata lugens strains. BPH, GST, RGSV, RRSV
10  2016 Carboxylesterases: General detoxifying enzymes. ---
11  2016 Chlorpyrifos-induced biomarkers in Japanese medaka (Oryzias latipes). AChE, CHL, GST
12  2016 Human Neural Stem Cells Overexpressing a Carboxylesterase Inhibit Bladder Tumor Growth. ---
13  2016 In vitro and in vivo studies of cholinesterases and carboxylesterases in Planorbarius corneus exposed to a phosphorodithioate insecticide: Finding the most sensitive combination of enzymes, substrates, tissues and recovery capacity. ChEs, OPs
14  2015 An in vitro screening with emerging contaminants reveals inhibition of carboxylesterase activity in aquatic organisms. PPCPs
15  2015 Clinically applicable human adipose tissue-derived mesenchymal stem cells delivering therapeutic genes to brainstem gliomas. GMP, hAT-MSC, sTRAIL
16  2014 Co-treatment with therapeutic neural stem cells expressing carboxyl esterase and CPT-11 inhibit growth of primary and metastatic lung cancers in mice. NSCs
17  2014 Feeding and digestive responses to fatty acid intake in two South American passerines with different food habits. FA
18  2014 Key amino acid associated with acephate detoxification by Cydia pomonella carboxylesterase based on molecular dynamics with alanine scanning and site-directed mutagenesis. CAS, MD
19  2013 Cholinesterases and neurotoxicity as highly sensitive biomarkers for an organophosphate insecticide in a freshwater gastropod (Chilina gibbosa) with low sensitivity carboxylesterases. CAT, ChE, GST, SOD
20  2013 Inhibition of porcine liver carboxylesterase by phosphorylated flavonoids. AChE, CEase, CES
21  2013 Modulation of esterified drug metabolism by tanshinones from Salvia miltiorrhiza ("Danshen"). ---
22  2013 Neural stem cell-mediated CE/CPT-11 enzyme/prodrug therapy in transgenic mouse model of intracerebellar medulloblastoma. CPT-11, NSCs
23  2012 Effects of genetically engineered stem cells expressing cytosine deaminase and interferon-beta or carboxyl esterase on the growth of LNCaP rrostate cancer cells. 5-FC, 5-FU, CD, hNSCs, IFN-beta
24  2012 Mechanisms of aggregation inhibition by aspirin and nitrate-aspirin prodrugs in human platelets. BuChE, NO, PRP, WP
25  2011 Bioefficacy of Alpinia galanga (Zingiberaceae) rhizome extracts, (E)-p-acetoxycinnamyl alcohol, and (E)-p-coumaryl alcohol ethyl ether against Bactrocera dorsalis (Diptera: Tephritidae) and the impact on detoxification enzyme activities. GST
26  2011 Organ-specific carboxylesterase profiling identifies the small intestine and kidney as major contributors of activation of the anticancer prodrug CPT-11. ---
27  2011 Requirements for mammalian carboxylesterase inhibition by substituted ethane-1,2-diones. ---
28  2010 Genomic analysis of the carboxylesterases: identification and classification of novel forms. ---
29  2010 Influence of the prodrugs 5-fluorocytosine and CPT-11 on ovarian cancer cells using genetically engineered stem cells: tumor-tropic potential and inhibition of ovarian cancer cell growth. 5-FC, CD, CPT-11, GESTECs
30  2010 Inhibition, recovery and oxime-induced reactivation of muscle esterases following chlorpyrifos exposure in the earthworm Lumbricus terrestris. ChE, OP
31  2010 Inter-conversion of catalytic abilities in a bifunctional carboxyl/feruloyl-esterase from earthworm gut metagenome. FAE
32  2010 Tissue-specific inhibition and recovery of esterase activities in Lumbricus terrestris experimentally exposed to chlorpyrifos. ChE, OP
33  2009 Esterase activities in the blood, liver and intestine of several preclinical species and humans. BChE, PON
34  2009 Improved, selective, human intestinal carboxylesterase inhibitors designed to modulate 7-ethyl-10-[4-(1-piperidino)-1-piperidino]carbonyloxycamptothecin (Irinotecan; CPT-11) toxicity. hiCE
35  2008 An improved human carboxylesterase for enzyme/prodrug therapy with CPT-11. rCE
36  2008 Effect of buffer components and carrier solvents on in vitro activity of recombinant human carboxylesterases. ---
37  2008 Efficient one-cycle affinity selection of binding proteins or peptides specific for a small-molecule using a T7 phage display pool. AChE, FKBP12, QCM, RELIC, SAM, SLF
38  2008 Immune-related proteins induced in the hemolymph after aseptic and septic injury differ in honey bee worker larvae and adults. AMPs, PO
39  2007 Analysis of mammalian carboxylesterase inhibition by trifluoromethylketone-containing compounds. TFK
40  2007 Analysis of the inhibition of mammalian carboxylesterases by novel fluorobenzoins and fluorobenzils. ---
41  2007 Cholinesterase inhibition and alterations of hepatic metabolism by oral acute and repeated chlorpyrifos administration to mice. ChE, CPF, CPFO
42  2007 Hypoxia-targeted over-expression of carboxylesterase as a means of increasing tumour sensitivity to irinotecan (CPT-11). HIF-1, HREs, PGK-1, rCE
43  2007 Identification of rat and human cytochrome p450 isoforms and a rat serum esterase that metabolize the pyrethroid insecticides deltamethrin and esfenvalerate. ---
44  2007 Planarity and constraint of the carbonyl groups in 1,2-diones are determinants for selective inhibition of human carboxylesterase 1. hiCE
45  2007 Selective inhibition of carboxylesterases by isatins, indole-2,3-diones. ---
46  2006 Carboxylesterases--detoxifying enzymes and targets for drug therapy. ---
47  2006 Monitoring the effects of water pollution on Cyprinus carpio in Karakaya Dam Lake, Turkey. AChE, ACP, AST, CF, GST, KDL, LDH
48  2006 Phenolic extracts from various Algerian plants as strong inhibitors of porcine liver carboxylesterase. ---
49  2006 Schedule-dependent cytotoxicity of 5-fluorouracil and irinotecan in a colon cancer cell line. 5-FU
50  2005 Activation and antitumor activity of CPT-11 in plasma esterase-deficient mice. SN-38G
51  2005 Adenoviral vector-mediated expression of a gene encoding secreted, EpCAM-targeted carboxylesterase-2 sensitises colon cancer spheroids to CPT-11. EpCAM
52  2005 Effect of carboxylesterase inhibition on the anti-tumour effects of irinotecan. BNPP
53  2005 Gene-directed enzyme prodrug therapy with carboxylesterase enhances the anticancer efficacy of the conditionally replicating adenovirus AdDelta24. CRAds, GDEPT, TK/GCV
54  2005 Identification and characterization of novel benzil (diphenylethane-1,2-dione) analogues as inhibitors of mammalian carboxylesterases. TRAP
55  2005 Inhibition of acetylcholinesterase by the anticancer prodrug CPT-11. AChE
56  2005 Malathion detoxification by human hepatic carboxylesterases and its inhibition by isomalathion and other pesticides. CPF, CPFO, MAL, MOx, OPT, PAR
57  2004 Discovery of novel selective inhibitors of human intestinal carboxylesterase for the amelioration of irinotecan-induced diarrhea: synthesis, quantitative structure-activity relationship analysis, and biological activity. QSAR
58  2004 Effect of chlorpromazine on human and murine intracellular carboxylesterases. CPZ
59  2004 Induction of apoptosis by AN-152, a cytotoxic analog of luteinizing hormone-releasing hormone (LHRH), in LHRH-R positive human breast cancer cells is independent of multidrug resistance-1 (MDR-1) system. FCS, LHRH, LHRH-R, MDR1
60  2004 Interactive toxicity of the organophosphorus insecticides chlorpyrifos and methyl parathion in adult rats. CPF, CPO, MPO, OP
61  2004 Mechanism of differential inhibition of hepatic and pancreatic fatty acid ethyl ester synthase by inhibitors of serine-esterases: in vitro and cell culture studies. 3-BCP, CBDP, ChE, FAEE, PN, TOTP
62  2003 Activation of a camptothecin prodrug by specific carboxylesterases as predicted by quantitative structure-activity relationship and molecular docking studies. hiCE, rCE
63  2003 Combined forced running stress and subclinical paraoxon exposure have little effect on pyridostigmine-induced acute toxicity in rats. ChE
64  2003 p53-mediated regulation of expression of a rabbit liver carboxylesterase confers sensitivity to 7-ethyl-10-[4-(1-piperidino)-1-piperidino]carbonyloxycamptothecin (CPT-11). WT
65  2003 Pharmacological and clinical properties of Xeloda (Capecitabine), a new oral active derivative of fluoropyrimidine. 5'-DFCR, 5'-DFUR, CD, TP
66  2001 Inhibition of the UCI-107 human ovarian carcinoma cell line by a targeted cytotoxic analog of somatostatin, AN-238. SST
67  2001 Sensitization of human tumor cells to CPT-11 via adenoviral-mediated delivery of a rabbit liver carboxylesterase. ---
68  2001 Structural constraints affect the metabolism of 7-ethyl-10-[4-(1-piperidino)-1-piperidino]carbonyloxycamptothecin (CPT-11) by carboxylesterases. ---
69  2000 Proficient metabolism of irinotecan by a human intestinal carboxylesterase. ---
70  2000 Use of the ornithine decarboxylase promoter to achieve N-MYC-mediated overexpression of a rabbit carboxylesterase to sensitize neuroblastoma cells to CPT-11. ODC
71  1999 In vivo and ex vivo gene therapy strategies to treat tumors using adenovirus gene transfer vectors. VEGF
72  1999 Metabolic inactivation of 2-oxiranylmethyl 2-ethyl-2,5-dimethylhexanoate (C10GE) in skin, lung and liver of human, rat and mouse. EH, GST
73  1999 [Antiesterase activity and toxicity of O,O-dialkyl-S-ethoxycarbonylbromomethylthiophosphates]. ACE, BCE
74  1998 Determinants of CPT-11 and SN-38 activities in human lung cancer cells. HPLC, NSCLC, SCLC
75  1998 Reversal of CPT-11 resistance of lung cancer cells by adenovirus-mediated gene transfer of the human carboxylesterase cDNA. ---
76  1997 Purification and characterization of rat liver microsomal fatty acid ethyl and 2-chloroethyl ester synthase and their relationship with carboxylesterase (pI 6.1). ChE, FACEES, FAEES
77  1996 [A comparative study of the cholinesterase and carboxylesterase sensitivities of mammals and arthropods to new phenyl and glycidyl esters of dialkyl thiophosphoric acid]. AChE, BuChE
78  1995 Localization of an isoform of carboxylesterase in rat brain differs from that in human brain. ---
79  1994 Blood esterase inhibition in birds as an index of organophosphorus contamination: field and laboratory studies. AChE, BChE
80  1994 Comparative localization of carboxylesterase in F344 rat, beagle dog, and human nasal tissue. ---
81  1994 Immunohistochemistry with an antibody to human liver carboxylesterase in human brain tissues. AD, ALS
82  1994 Studies on a novel series of acyl ester prodrugs of prostaglandin F2 alpha. AChE, BuChE, PGF2 alpha
83  1994 [A comparative study of carboxylesterase in the white mouse and in the caterpillar of the cotton bollworm Heliothes armigera]. IPhAc, p-NPhAc
84  1991 Cloning and analysis of a cDNA encoding a human liver carboxylesterase. aa
85  1986 Species and tissue characteristic carboxyesterases (CE) pattern of chimaeric embryos. ---
86  1985 Aprophen: a substrate and inhibitor of butyrylcholinesterase and carboxylesterases. BTC, BuChE
87  1984 Isoelectrically focused carboxyesterases as a biological marker in chimeras. IEF
88  1983 Kinetic and structural relationships of transition monomeric and oligomeric carboxyl- and choline-esterases. ChE, mCE, oCE
89  1975 The influence of phenobarbitone on maternal and perinatal hepatic drug-metabolizing enzymes in the rat. OD, PB