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Abbreviation : CG
Long Form : cathepsin G
No. Year Title Co-occurring Abbreviation
2019 Cathepsin G Activity as a New Marker for Detecting Airway Inflammation by Microscopy and Flow Cytometry. ---
2019 Cathepsin G cleaves and activates IL-36gamma and promotes the inflammation of psoriasis. FL, NE, NETs
2019 Neutrophil Cathepsin G Regulates Dendritic Cell Production of IL-12 during Development of CD4 T Cell Responses to Antigens in the Skin. CHS, DNFB, WT
2019 Peptidomimetic inhibitors targeting the membrane-binding site of the neutrophil proteinase 3. mbPR3, NE, PR3
2019 The effect of neutrophil serine proteases on human nasal epithelial cell barrier function. CBF, ELISA, HNEC-ALI, IL-6, NE, PE, PR3, TER, ZO-1
2018 Lung tissue destruction by proteinase 3 and cathepsin G mediated elastin degradation is elevated in chronic obstructive pulmonary disease. COPD, ELISA, PR3
2018 Molecular network, pathway, and functional analysis of time-dependent gene changes related to cathepsin G exposure in neonatal rat cardiomyocytes. IPA, NRCMs
2017 Cathepsin G Is Expressed by Acute Lymphoblastic Leukemia and Is a Potential Immunotherapeutic Target. ALL, AML, RPPA
2017 Insulin-like growth factor-1 signaling is responsible for cathepsin G-induced aggregation of breast cancer MCF-7 cells. IGF-1
10  2017 Neutrophils and neutrophil serine proteases are increased in the spleens of estrogen-treated C57BL/6 mice and several strains of spontaneous lupus-prone mice. MPO, NE, NSPs, PR3
11  2017 Neutrophils can disarm NK cell response through cleavage of NKp46. CF, MS, PMNs, PR3
12  2016 Disequilibrium of Blood Coagulation and Fibrinolytic System in Patients With Coronary Artery Ectasia. alpha1-AT, alpha2-MG, alpha2-PI, CAD, CAE, HNE, PR3
13  2016 Neutrophil serine proteases and their endogenous inhibitors in coronary artery ectasia patients. alpha1-PI, alpha2-MG, CAD, CAE, HNE, IL-8, NSPs, PR3, sElastin, SLPI, TNF-alpha
14  2015 Cathepsin G in Experimental Tuberculosis: Relevance for Antibacterial Protection and Potential for Immunotherapy. NE
15  2015 Processing of Neutrophil alpha-Defensins Does Not Rely on Serine Proteases In Vivo. HNPs, NE, PR3
16  2015 Thrombospondin-1 restrains neutrophil granule serine protease function and regulates the innate immune response during Klebsiella pneumoniae infection. NE, TSP-1, WT
17  2014 Mechanism of neutrophil dysfunction: neutrophil serine proteases cleave and inactivate the C5a receptor. CF, NE, NSP
18  2013 A novel HLA-A*0201 restricted peptide derived from cathepsin G is an effective immunotherapeutic target in acute myeloid leukemia. AML, CTL
19  2013 Global substrate profiling of proteases in human neutrophil extracellular traps reveals consensus motif predominantly contributed by elastase. NE, NETs, NSP4, PMA, PR3
20  2013 Identification of a 14 kDa endocan fragment generated by cathepsin G, a novel circulating biomarker in patients with sepsis. ICU, NE, PR3
21  2013 SerpinB1 is critical for neutrophil survival through cell-autonomous inhibition of cathepsin G. BM, NE, PMNs
22  2013 Study about correlation of anti-neutrophil cytoplasmic antibodies and anticardiolipin antibodies with thromboangiitis obliterans. ACA, ANCA, ASO, BPI, ELISA, IIF, LF, MPO, PR3, TAO
23  2013 Targeting cathepsin G in myeloid leukemia. ---
24  2012 Cathepsin G and neutrophil elastase contribute to lung-protective immunity against mycobacterial infections in mice. BCG, NE
25  2012 Cathepsin G induces cell aggregation of human breast cancer MCF-7 cells via a 2-step mechanism: catalytic site-independent binding to the cell surface and enzymatic activity-dependent induction of the cell aggregation. ---
26  2012 High fidelity processing and activation of the human alpha-defensin HNP1 precursor by neutrophil elastase and proteinase 3. NE, PR3
27  2012 NSP4, an elastase-related protease in human neutrophils with arginine specificity. NE, NSPs, PR3
28  2012 The action of neutrophil serine proteases on elastin and its precursor. HLE, PR3
29  2011 Antineutrophil cytoplasmic antibodies against myeloperoxidase, proteinase 3, elastase, cathepsin G and lactoferrin in Japanese patients with rheumatoid arthritis. ANCAs, EL, JS, LF, MPO, PR3, RA
30  2011 Cathepsin G and neutrophil elastase play critical and nonredundant roles in lung-protective immunity against Streptococcus pneumoniae in mice. FRET, KO, NE, PR3
31  2011 Discriminating between the activities of human cathepsin G and chymase using fluorogenic substrates. ---
32  2011 Tailor-made inflammation: how neutrophil serine proteases modulate the inflammatory response. NE, NSPs, PR3
33  2011 Tamm-Horsfall glycoprotein enhances PMN phagocytosis by binding to cell surface-expressed lactoferrin and cathepsin G that activates MAP kinase pathway. LF, PEA, PMN, THP
34  2010 Study of interaction of ceruloplasmin with serprocidins. Cp, NE, PR3
35  2008 In vitro activation of the rhesus macaque myeloid alpha-defensin precursor proRMAD-4 by neutrophil serine proteinases. NE
36  2008 Modulation of tissue factor and tissue factor pathway inhibitor-1 by neutrophil proteases. PR3, TF, TFPI
37  2008 Single residue determines the specificity of neutrophil elastase for Shigella virulence factors. NE
38  2007 The sulfate groups of chondroitin sulfate- and heparan sulfate-containing proteoglycans in neutrophil plasma membranes are novel binding sites for human leukocyte elastase and cathepsin G. HLE, PMSF
39  2005 Antineutrophil cytoplasmic antibodies in Bulgarian patients with rheumatoid arthritis: characterization and clinical associations. ANCA, BPI, ELISA, Ig, LE, LF, MPO, PR3, RA
40  2005 Effects of elastase and cathepsin G on the levels of membrane and soluble TNFalpha. iNOS, mTNF-alpha, NE, PMN, proTNFalpha, sTNFalpha
41  2004 Characterization of hematopoietic progenitor mobilization in protease-deficient mice. G-CSF, HPC, MMP-9, NE, VCAM-1
42  2004 Neutrophil-derived MMP-9 mediates synergistic mobilization of hematopoietic stem and progenitor cells by the combination of G-CSF and the chemokines GRObeta/CXCL2 and GRObetaT/CXCL2delta4. G-CSF, MMP-9, NE, PBSCs, PMN
43  2003 Prevalence of ANCA in mixed cryoglobulinemia and chronic hepatitis C virus infection. ANCA, BPI, CV, ELISA, HCV, IFT, MC
44  2003 Regulation of protease-activated receptor-1 in mononuclear cells by neutrophil proteases. COPD, NE, PARs
45  2003 The major cold shock gene, cspA, is involved in the susceptibility of Staphylococcus aureus to an antimicrobial peptide of human cathepsin G. CspA
46  2003 [Antineutrophil cytoplasmic antibody associated vasculitis induced by antithyroid agents]. ANA, ANCA, AZU, BPI, HLE, IIF, LF, MMI, MPO, PR3, PTU
47  2002 Dipeptidyl peptidase I activates neutrophil-derived serine proteases and regulates the development of acute experimental arthritis. DPPI, NE, PR3
48  2002 [Clinicopathological characteristics of propylthiouracil-induced antineutrophil cytoplasmic antibodies-positive vasculitis and their target antigens: a report of 4 cases and literature review]. ANCA, AZU, BPI, HLE, LF, MPO, PR3, PTU
49  2000 Human neutrophil cathepsin G down-regulates LPS-mediated monocyte activation through CD14 proteolysis. LPS, TNF-alpha
50  2000 Phosphoinositide 3-kinase inhibition reverses platelet aggregation triggered by the combination of the neutrophil proteinases elastase and cathepsin G without impairing alpha(IIb)beta(3) integrin activation. IIb, NE, PI 3-K
51  1999 Generation of PSA-ACT-specific monoclonal antibodies and their application in a sandwich immunoassay. ACT, AUC, BPH, fPSA, mAb, MG, PCa, PSA
52  1999 Purification and N-terminal amino acid sequence of sheep neutrophil cathepsin G and elastase. NE
53  1999 [The diagnostic significance of antineutrophil cytoplasmic antibodies in ulcerative colitis]. ANCA, BPI, ELISA, IIF, LF, MPO, PR3, UC
54  1997 Anti-neutrophil cytoplasmic antibody (ANCA) in malaria is directed against cathepsin G. a-ANCA, ANCA, HLE, IIF, LF, MPO, PR3
55  1996 Antineutrophil cytoplasmic antibodies in rheumatoid arthritis patients. ANCAs, DI-LE, ELISA, Ely RA, HLE, IIF, LF, LSRA, MPO, Pso, RA, RAV, SLE
56  1996 Antineutrophil cytoplasmic antibodies in systemic lupus erythematosus. ANA, ANCA, IIF, LF, MPO, PR3, SLE
57  1996 Proteolysis of thrombospondin during cathepsin-G-induced platelet aggregation: functional role of the 165-kDa carboxy-terminal fragment. Fg, HBD, TSP-1
58  1994 Early myeloid cell-specific expression of the human cathepsin G gene in transgenic mice. ---
59  1994 Granulocyte proteases and hydrogen peroxide synergistically inactivate thrombomodulin of endothelial cells in vitro. GE, HUVECs, TM
60  1994 Neutrophil proteinase cathepsin G is proteolytically active on the human platelet glycoprotein Ib-IX receptor: characterization of the cleavage sites within the glycoprotein Ib alpha subunit. GP
61  1994 Regulation of the structure and activity of platelet adhesion receptors by leukocyte proteinases. EL
62  1993 Antineutrophil cytoplasmic antibodies in rheumatoid arthritis. Characterization and clinical correlations. ANCA, ELISA, LF, MPO, RA
63  1993 Molecular cloning, chromosomal location, and tissue-specific expression of the murine cathepsin G gene. hCG, pre
64  1992 A-T-rich scaffold attachment regions flank the hematopoietic serine protease genes clustered on chromosome 14q11.2. ARS, SARs, topo II
65  1990 Characteristics of the chemotactic activity of heparin cofactor II proteolysis products. alpha 1-PI, fMLP, HCII
66  1990 Mechanisms of extracellular matrix proteoglycan degradation by human neutrophils. CB, ECM, fMLP, LF, NE, PG, PMN, SMC
67  1990 [Effect of the products released from the activated human neutrophils and endotoxin on bovine pulmonary endothelial cells]. ET, HNE, HX, XO
68  1989 Elastase and cathepsin G of human monocytes. Quantification of cellular content, release in response to stimuli, and heterogeneity in elastase-mediated proteolytic activity. HLE, PMN
69  1989 Heparin cofactor II-proteinase reaction products exhibit neutrophil chemoattractant activity. HCII
70  1989 Neutrophil cathepsin G increases calcium flux and inositol polyphosphate production in cultured endothelial cells. ENDO