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Abbreviation : CG
Long Form : cycloguanil
No. Year Title Co-occurring Abbreviation
2014 The antimalarial drug proguanil is an antagonist at 5-HT3 receptors. CPB, mCPBG
2006 Sensitive method for the quantitative determination of proguanil and its metabolites in rat blood and plasma by liquid chromatography-mass spectrometry. 4CPB, PG
2003 Pregnancy and use of oral contraceptives reduces the biotransformation of proguanil to cycloguanil. OCP, PG
2000 In vitro proguanil activation to cycloguanil is mediated by CYP2C19 and CYP3A4 in adult Chinese liver microsomes. PG
1996 Pharmacokinetic evaluation of proguanil: a probe phenotyping drug for the mephenytoin hydroxylase polymorphism. PG
1996 Simultaneous measurement of proguanil and its metabolites in human plasma and urine by reversed-phase high-performance liquid chromatography, and its preliminary application in relation to genetically determined S-mephenytoin 4'-hydroxylation status. CPB, HPLC, PG
1995 Metabolic disposition of proguanil in extensive and poor metabolisers of S-mephenytoin 4'-hydroxylation recruited from an Indonesian population. CPB, PG
1991 The activation of the biguanide antimalarial proguanil co-segregates with the mephenytoin oxidation polymorphism--a panel study. EMs, PG
1990 In vitro metabolism of the biguanide antimalarials in human liver microsomes: evidence for a role of the mephenytoin hydroxylase (P450 MP) enzyme. CCG, CPG, PG
10  1987 Single dose pharmacokinetics of proguanil and its metabolites in healthy subjects. CPB