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Abbreviation : CGI-58
Long Form : comparative gene identification-58
No. Year Title Co-occurring Abbreviation
2020 The Gene and Protein Expression of the Main Components of the Lipolytic System in Human Myocardium and Heart Perivascular Adipose Tissue. Effect of Coronary Atherosclerosis. ATGL, CAD, DG, G0S2, TG
2020 Western diet induces severe nonalcoholic steatohepatitis, ductular reaction, and hepatic fibrosis in liver CGI-58 knockout mice. LDs, LivKO, NAFLD, NASH
2019 Assessment of the Main Compounds of the Lipolytic System in Treadmill Running Rats: Different Response Patterns between the Right and Left Ventricle. ATGL, DG, FFA, G0S2, HSL, PGC-1alpha, TG
2019 ATGL/CGI-58-Dependent Hydrolysis of a Lipid Storage Pool in Murine Enterocytes. ATGL, cLDs, iDKO
2019 Bariatric Surgery in Rats Upregulates FSP27 Expression in Fat Tissue to Affect Fat Hydrolysis and Metabolism. ATGL, HSL, LDs, RYGB, SG, WAT
2019 Effect of acute exercise on mRNA and protein expression of main components of the lipolytic complex in different skeletal muscle types in the rat. ATGL, G0S2, RG
2019 Effects of short-term prednisolone treatment on indices of lipolysis and lipase signaling in abdominal adipose tissue in healthy humans. ANGPTL4, G0S2, GC, PKA
2019 Hepatic lipid droplet breakdown through lipolysis during hibernation in Chinese Soft-Shelled Turtle (Pelodiscus sinensis). ATGL, cAMP, FAs, LD, PKA, TG
2019 PNPLA3, CGI-58, and Inhibition of Hepatic Triglyceride Hydrolysis in Mice. ATGL, KO, LDs, PNPLA3, TG, WT
10  2017 Adipocyte STAT5 deficiency promotes adiposity and impairs lipid mobilisation in mice. JAK
11  2017 Critical roles for alpha/beta hydrolase domain 5 (ABHD5)/comparative gene identification-58 (CGI-58) at the lipid droplet interface and beyond. ABHD5, ABHD5, ATGL, NLSDI, TAG
12  2017 Effects of insulin-induced hypoglycaemia on lipolysis rate, lipid oxidation and adipose tissue signalling in human volunteers: a randomised clinical study. ATGL, G0S2, HE, HH, HSL, PKA
13  2017 G0S2: A small giant controller of lipolysis and adipose-liver fatty acid flux. ATGL, FA, G0S2
14  2017 Increased Triacylglycerol Lipase Activity in Adipose Tissue of Lean and Obese Men During Endurance Exercise. ATGL, HSL
15  2017 Lipases and lipid droplet-associated protein expression in subcutaneous white adipose tissue of cachectic patients with cancer. ATGL, CC, HSL, IC, TC, TNF-alpha, WSC
16  2017 Lipolysis in Brown Adipocytes Is Not Essential for Cold-Induced Thermogenesis in Mice. BAT, LD, WAT
17  2017 Minimal alteration in muscle lipid genes following stabilized weight loss. ATGL, CPT-1, CWL, EWL, IMCL, LDS, mRNA, PGC-1alpha, PLIN2
18  2017 Skin Barrier Development Depends on CGI-58 Protein Expression during Late-Stage Keratinocyte Differentiation. ATGL
19  2016 Combined Insulin Deficiency and Endotoxin Exposure Stimulate Lipid Mobilization and Alter Adipose Tissue Signaling in an Experimental Model of Ketoacidosis in Subjects With Type 1 Diabetes: A Randomized Controlled Crossover Trial. ATGL, DKA, G0S2
20  2016 Effects of abhydrolase domain containing 5 gene (ABHD5) expression and variations on chicken fat metabolism. ABHD5, ATGL
21  2016 Macrophage CGI-58 Attenuates Inflammatory Responsiveness via Promotion of PPARgamma Signaling. ATGL, HDAC, HFD, LPS, PPAR, TG, TG, WT
22  2016 Pronounced expression of the lipolytic inhibitor G0/G1 Switch Gene 2 (G0S2) in adipose tissue from brown bears (Ursus arctos) prior to hibernation. ATGL, CIDE, FFA, G0S2
23  2016 Reassessing the Potential Activities of Plant CGI-58 Protein. ATGL, TAG
24  2016 Regulation of Hepatic Triacylglycerol Metabolism by CGI-58 Does Not Require ATGL Co-activation. ATGL, DAG, TAG
25  2015 ATGL and CGI-58 are lipid droplet proteins of the hepatic stellate cell line HSC-T6. ATGL, HSCs, LDs, REs
26  2015 Characterization of lipolytic inhibitor G(0)/G(1) switch gene-2 protein (G0S2) expression in male Sprague-Dawley rat skeletal muscle compared to relative content of adipose triglyceride lipase (ATGL) and comparitive gene identification-58 (CGI-58). ATGL, G0S2, G0S2, RG, SOL, WG
27  2015 Dynamic subcellular localization of aquaporin-7 in white adipocytes. AQP7
28  2015 Effect of Bariatric Weight Loss on the Adipose Lipolytic Transcriptome in Obese Humans. ATGL, HbA1C, HSL, TG
29  2015 Fasting-induced G0/G1 switch gene 2 and FGF21 expression in the liver are under regulation of adipose tissue derived fatty acids. AT, FAs, G0S2, TG
30  2015 Fatty Acid-binding Proteins Interact with Comparative Gene Identification-58 Linking Lipolysis with Lipid Ligand Shuttling. A-FABP, ATGL, FABP, TG
31  2015 Macrophage CGI-58 deficiency promotes IL-1beta transcription by activating the SOCS3-FOXO1 pathway. FOXO1, HFD, IL, LPS, NEFA, SOCS3
32  2015 Muscle-specific deletion of comparative gene identification-58 (CGI-58) causes muscle steatosis but improves insulin sensitivity in male mice. TG
33  2015 Perilipin 5 improves hepatic lipotoxicity by inhibiting lipolysis. ATGL, LDs, NEFAs, Plin5, TG
34  2015 Piecing together the puzzle of perilipin proteins and skeletal muscle lipolysis. ATGL
35  2015 Structure of a CGI-58 motif provides the molecular basis of lipid droplet anchoring. ATGL, LDs, TGs
36  2015 Topiramate effects lipolysis in 3T3-L1 adipocytes. ATGL, CNS, HSL, PKA, TPM
37  2014 CGI-58, a key regulator of lipid homeostasis and signaling in plants, also regulates polyamine metabolism. SPDS1
38  2014 Comparative gene identification 58/alpha/beta hydrolase domain 5 lacks lysophosphatidic acid acyltransferase activity. ABHD5, ATGL, LPAAT
39  2014 Comparative gene identification-58 (CGI-58) promotes autophagy as a putative lysophosphatidylglycerol acyltransferase. PG
40  2014 Comparative gene identification-58/alpha/beta hydrolase domain 5: more than just an adipose triglyceride lipase activator? ATGL, LPAAT
41  2014 Deletion of CGI-58 or adipose triglyceride lipase differently affects macrophage function and atherosclerosis. ATGL, DKO
42  2014 Differential expressions of G0/G1 switch gene 2 and comparative gene identification-58 are associated with fat content in bovine muscle. G0S2, IMF, LM
43  2014 Intestinal Cgi-58 deficiency reduces postprandial lipid absorption. LD, TG
44  2014 Loss of abhd5 promotes colorectal tumor development and progression by inducing aerobic glycolysis and epithelial-mesenchymal transition. Abhd5, CRCs
45  2014 Placental lipases in pregnancies complicated by gestational diabetes mellitus (GDM). ATGL, EL, GDM, HSL, LPL
46  2014 Regulation of adipocyte lipolysis. HSL
47  2014 The effect of inhibition of endoplasmic reticulum stress on lipolysis in white adipose tissue in a rat model of chronic kidney disease. ATGL, CKD, eIF, ER, HSL, RRM
48  2014 The hepatitis C virus core protein inhibits adipose triglyceride lipase (ATGL)-mediated lipid mobilization and enhances the ATGL interaction with comparative gene identification 58 (CGI-58) and lipid droplets. ATGL, HCV, LDs, TG
49  2014 Transgenic CGI-58 expression in macrophages alleviates the atherosclerotic lesion development in ApoE knockout mice. ATGL, BM, Mac-CGI-58 Tg, TG, WT
50  2013 Biochemistry and pathophysiology of intravascular and intracellular lipolysis. ATGL, FAs, GPIHBP1, TGs
51  2013 Cardiac-specific overexpression of perilipin 5 provokes severe cardiac steatosis via the formation of a lipolytic barrier. ATGL, CM, CM-Plin5, FA, LD, Plin5, TG
52  2013 CGI-58 knockdown sequesters diacylglycerols in lipid droplets/ER-preventing diacylglycerol-mediated hepatic insulin resistance. ASO, DAG
53  2013 Deficiency of liver Comparative Gene Identification-58 causes steatohepatitis and fibrosis in mice. LivKO, NAFLDs, TG
54  2013 Downregulation of adipose triglyceride lipase in the heart aggravates diabetic cardiomyopathy in db/db mice. ATGL, TG
55  2013 Functional cardiac lipolysis in mice critically depends on comparative gene identification-58. ATGL, TG
56  2013 IL-6 and epinephrine have divergent fiber type effects on intramuscular lipolysis. ATGL, EDL, rIL-6
57  2013 Skeletal muscle PLIN proteins, ATGL and CGI-58, interactions at rest and following stimulated contraction. ATGL
58  2013 The alpha/beta hydrolase CGI-58 and peroxisomal transport protein PXA1 coregulate lipid homeostasis and signaling in Arabidopsis. PXA1, TAG
59  2013 [Function of comparative gene identification-58 (CGI-58) on lipid metabolism in animals]. ATGL, LDs, LPAAT
60  2012 Alternative splicing and developmental and hormonal regulation of porcine comparative gene identification-58 (CGI-58) mRNA. ATGL, LPAAT, ORF, S-V
61  2012 CGI-58/ABHD5-derived signaling lipids regulate systemic inflammation and insulin action. LPA, TAG
62  2012 Effects of lipoic acid on lipolysis in 3T3-L1 adipocytes. G0S2, HSL, LA
63  2012 G0/G1 switch gene-2 regulates human adipocyte lipolysis by affecting activity and localization of adipose triglyceride lipase. ATGL, G0S2
64  2012 Steatohepatitis and liver cirrhosis in Chanarin-Dorfman syndrome with a new ABDH5 mutation. CDS
65  2011 Acute up-regulation of adipose triglyceride lipase and release of non-esterified fatty acids by dexamethasone in chicken adipose tissue. ATGL, G0S2, NEFA
66  2011 Adipose triglyceride lipase expression in human adipose tissue and muscle. Role in insulin resistance and response to training and pioglitazone. ATGL, mRNA
67  2011 Cloning of comparative gene identification-58 gene in avian species and investigation of its developmental and nutritional regulation in chicken adipose tissue. ATGL
68  2011 Recent insights into the structure and function of comparative gene identification-58. ---
69  2011 The minimal domain of adipose triglyceride lipase (ATGL) ranges until leucine 254 and can be activated and inhibited by CGI-58 and G0S2, respectively. ATGL, G0S2, TGs
70  2010 CGI-58 knockdown in mice causes hepatic steatosis but prevents diet-induced obesity and glucose intolerance. ASOs, HFD, TG
71  2010 Dysregulation of lipolysis and lipid metabolism in visceral and subcutaneous adipocytes by high-fat diet: role of ATGL, HSL, and AMPK. AMPK, ATGL, HFD, HSL
72  2010 Growth retardation, impaired triacylglycerol catabolism, hepatic steatosis, and lethal skin barrier defect in mice lacking comparative gene identification-58 (CGI-58). ABHD-5, ATGL, TG
73  2010 Hormone-sensitive lipase is critical mediators of acute exercise-induced regulation of lipolysis in rat adipocytes. HSL
74  2010 Identification of a novel splicing isoform of murine CGI-58. ---
75  2010 The N-terminal region of comparative gene identification-58 (CGI-58) is important for lipid droplet binding and activation of adipose triglyceride lipase. ATGL
76  2009 Adipose triglyceride lipase in human skeletal muscle is upregulated by exercise training. ATGL, DGAT1, HSL, IMTG, TG
77  2008 Lipid droplets in lipogenesis and lipolysis. ADRP, ATGL, LSDP5, MLDP, OXPAT, SNAREs, TIP47
78  2007 CGI-58 facilitates lipolysis on lipid droplets but is not involved in the vesiculation of lipid droplets caused by hormonal stimulation. LD
79  2007 CGI-58 facilitates the mobilization of cytoplasmic triglyceride for lipoprotein secretion in hepatoma cells. TG