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Abbreviation : CHX
Long Form : cycloheximide
No. Year Title Co-occurring Abbreviation
2020 Andrias davidianus ranavirus 1R encoding a delayed-early protein promotes cell proliferation by driving cell cycle progression into S phase. ADRV-1R, DE, GSTCs, hpi, VLTF3 like, vTF
2020 CAPN1 promotes malignant behavior and erlotinib resistance mediated by phosphorylation of c-Met and PIK3R2 via degrading PTPN1 in lung adenocarcinoma. CAPN1, CCK-8, IHC, LUAD, qRT-PCR
2020 Comparative analysis of cell-free DNA content in culture medium and mitochondrial DNA copy number in porcine parthenogenetically activated embryos. CB, mtDNA, SCM
2020 EGFR-ERK pathway regulates CSN6 to contribute to PD-L1 expression in glioblastoma. CSN6, EGF, GBM
2020 EIF3H promotes aggressiveness of esophageal squamous cell carcinoma by modulating Snail stability. co-IP, EIF3H, ESCC, IHC
2020 Fluoxetine Induces Apoptotic and Oxidative Neuronal Death Associated with The Influx of Copper Ions in Cultured Neuronal Cells. BCPS, ROS
2020 Forget the stress: retrograde amnesia for the stress-induced impairment of extinction retrieval. ---
2020 NR4A1 promotes TNF‑alpha‑induced chondrocyte death and migration injury via activating theAMPK/Drp1/mitochondrial fission pathway. AMPK, Drp1, mPTP, NR4A1
2020 Production of collared peccary (Pecari tajacu Linnaeus, 1758) parthenogenic embryos following different oocyte chemical activation and invitro maturation conditions. ARTs, COC, EGF, IVM
10  2020 Regulation of SRF protein stability by an autophagy-dependent pathway. ALP, SRF, UPS
11  2020 SHCBP1 promotes tumor cell proliferation, migration, and invasion, and is associated with poor prostate cancer prognosis. LATS1, MDM2, PCa, SHCBP1, TP53
12  2020 Stabilization of the histone acetyltransferase Tip60 by deubiquitinating enzyme USP7 stimulates the release of pro-inflammatory mediators in acute lung injury. ALI, LPS, MPO, Tip60, USP7
13  2020 Thalidomide targets EGFL6 to inhibit EGFL6/PAX6 axis-driven angiogenesis in small bowel vascular malformation. OGIB, SBVM
14  2020 The mitochondrial K-ATP channel opener diazoxide upregulates STIM1 and Orai1 via ROS and the MAPK pathway in adult rat cardiomyocytes. 5-HD, NAC, qRT-PCR, ROS
15  2020 The SUMO Conjugase Ubc9 Protects Dopaminergic Cells from Cytotoxicity and Enhances the Stability of alpha-Synuclein in Parkinson's Disease Models. EGFP, PD, PFFs, PTM, qRT-PCR, ROS, SUMO, WT
16  2019 Activation of EGFR-DNA-PKcs pathway by IGFBP2 protects esophageal adenocarcinoma cells from acidic bile salts-induced DNA damage. ABS, BE, EAC, GERD, IGFBP-2
17  2019 Antiapoptotic activity of Chlamydia trachomatis Pgp3 protein involves activation of the ERK1/2 pathway mediated by upregulation of DJ-1 protein. si-DJ-1
18  2019 Curcumin Promotes Connexin 43 Degradation and Temozolomide-Induced Apoptosis in Glioblastoma Cells. ABC transporters, Cx43, EMT, GBM, TMZ
19  2019 Effect of single and combined treatments with MPF or MAPK inhibitors on parthenogenetic haploid activation of bovine oocytes. DhL, Io, PN, Rosc
20  2019 Evidence of necroptosis in osteoarthritic disease: investigation of blunt mechanical impact as possible trigger in regulated necrosis. IHC, PTOA
21  2019 Expression of mutant mRNA and protein in pancreatic cells derived from MODY3- iPS cells. HNF1A, MODY, MODY3-iPS, NMD, PTC, SeV, WB
22  2019 Global translation inhibition yields condition-dependent de-repression of ribosome biogenesis mRNAs. Ribi
23  2019 Glucose causes primary necrosis in exponentially grown yeast Saccharomyces cerevisiae. PS, SICD
24  2019 Long non-coding RNA MEG3 inhibits cervical cancer cell growth by promoting degradation of P-STAT3 protein via ubiquitination. p-STAT3, RIP
25  2019 MiR-29b/Sp1/FUT4 axis modulates the malignancy of leukemia stem cells by regulating fucosylation via Wnt/beta-catenin pathway in acute myeloid leukemia. ActD, AML, LSCs
26  2019 Novel Drug Delivery Approach via Self-Microemulsifying Drug Delivery System for Enhancing Oral Bioavailability of Asenapine Maleate: Optimization, Characterization, Cell Uptake, and In Vivo Pharmacokinetic Studies. AM
27  2019 Nrf2⁻ARE Signaling Acts as Master Pathway for the Cellular Antioxidant Activity of Fisetin. ARE, GCLC, GCLM, HO-1, Keap1, NQO1, Nrf2
28  2019 Optimization of parthenogenetic activation of rabbit oocytes and development of rabbit embryo by somatic cell nuclear transfer. 6-DMAP, DC, FBS, ION, PA, RFFs, SCNT
29  2019 Ribosome queuing enables non-AUG translation to be resistant to multiple protein synthesis inhibitors. PICs
30  2019 The beta-galactoside alpha2,6-sialyltranferase 1 (ST6GAL1) inhibits the colorectal cancer metastasis by stabilizing intercellular adhesion molecule-1 via sialylation. CRC, ICAM-1, MS
31  2019 The host cell ubiquitin ligase protein CHIP is a potent suppressor of HIV-1 replication. HIV-1, LTR
32  2019 Tylophorine reduces protein biosynthesis and rapidly decreases cyclin D1, inhibiting vascular smooth muscle cell proliferation in vitro and in organ culture. TYL, VSMC
33  2019 Versatile Synthetic Route to Cycloheximide and Analogues That Potently Inhibit Translation Elongation. SAR
34  2018 5-Azacytidine specifically inhibits the NIH-3T3 PCD process induced by TNF-alpha and cycloheximide via affecting BCL-XL. 5-AC, PCD
35  2018 A Cycloheximide-Sensitive Step in Transverse Microtubule Array Patterning. ---
36  2018 A Proteomic-Based Approach to Study the Mechanism of Cytotoxicity Induced by Interleukin-1alpha and Cycloheximide. ELISA, IL-1alpha, MS, PDI, TNF-alpha
37  2018 Alteration of Androgen Receptor Protein Stability by Triptolide in LNCaP Cells. AR, PCa
38  2018 Basic fibroblast growth factor regulates phosphate/pyrophosphate regulatory genes in stem cells isolated from human exfoliated deciduous teeth. ALPL, bFGF, COL1A1, DMP1, FGFR, Osx, Pi, SHEDs
39  2018 Characterization of Non-amyloidogenic G101S Transthyretin. TTR, WT
40  2018 Circular RNA‑MTO1 suppresses breast cancer cell viability and reverses monastrol resistance through regulating the TRAF4/Eg5 axis. circRNAs, TRAF4
41  2018 Distinct mechanistic responses to replication fork stalling induced by either nucleotide or protein deprivation. ---
42  2018 Genetic and functional analysis of two missense DUOX2 mutations in congenital hypothyroidism and goiter. CH, DUOX2
43  2018 Green Fluorescent Protein-Based Viability Assay in a Multiparametric Configuration. GFP, OTA, PI
44  2018 Increase in anti-apoptotic molecules, nucleolin, and heat shock protein 70, against upregulated LRRK2 kinase activity. dSY5Y, HSP70, LRRK2, NCL, PD
45  2018 Knockdown of REGgamma inhibits the proliferation and migration and promotes the apoptosis of multiple myeloma cells by downregulating NF-kappaB signal pathway. Bcl-xL, CCK-8, MM, MMP2, p-p65, XIAP
46  2018 Long Non-Coding RNA CYP4B1-PS1-001 Inhibits Proliferation and Fibrosis in Diabetic Nephropathy by Interacting with Nucleolin. MMCs, NCL
47  2018 Mitoxantrone is More Toxic than Doxorubicin in SH-SY5Y Human Cells: A 'Chemobrain' In Vitro Study. DOX, MTX, NAC, NR
48  2018 Molecular mechanisms of cutis laxa- and distal renal tubular acidosis-causing mutations in V-ATPase a subunits, ATP6V0A2 and ATP6V0A4. V-ATPase
49  2018 New use for CETSA: monitoring innate immune receptor stability via post-translational modification by OGT. CETSA, Nod2, OGT
50  2018 Reconsolidation of appetitive odor discrimination requires protein synthesis only when reactivation includes prediction error. CHX/PE, VEH, VEH
51  2018 RNA helicase DDX5 participates in oxLDL-induced macrophage scavenger receptor 1 expression by suppressing mRNA degradation. ActD, IPs, oxLDL, qRT-PCR, R-IPs
52  2018 Scutellaria baicalensis targets the hypoxia-inducible factor-1alpha and enhances cisplatin efficacy in ovarian cancer. HIF-1alpha, OC, SB, TCM
53  2018 Soluble TNF-like weak inducer of apoptosis (TWEAK) enhances poly(I:C)-induced RIPK1-mediated necroptosis. TWEAK
54  2018 [Mutations of G38R and D40G cause amyotrophic lateral sclerosis by reducing Annexin A11 protein stability]. ALS, ANXA11
55  2017 A novel puromycin decorporation method to quantify skeletal muscle protein breakdown: A proof-of-concept study. DEX, MPB, TNF-alpha
56  2017 Adenylyl cyclase mRNA localizes to the posterior of polarized DICTYOSTELIUM cells during chemotaxis. ACA, cAMP, FISH
57  2017 Communication or Toxicity: What Is the Effect of Cycloheximide on Leaf-Cutting Ant Workers? ---
58  2017 Comparison of whole animal costs of protein synthesis among polar and temperate populations of the same species of gammarid amphipod. ---
59  2017 Cten promotes epithelial-mesenchymal transition through the post-transcriptional stabilization of Snail. CRC, EMT
60  2017 Cx32 inhibits TNFalpha-induced extrinsic apoptosis with and without EGFR suppression. 18alpha-GA, Cx32, Dox, EGFR, GJIC, TNF-alpha, TRAIL
61  2017 Delayed Degradation and Impaired Dendritic Delivery of Intron-Lacking EGFP-Arc/Arg3.1 mRNA in EGFP-Arc Transgenic Mice. EJC, IEG, NMD
62  2017 Detection and Quantification of Nuclear Morphology Changes in Apoptotic Cells by Fluorescence Microscopy and Subsequent Analysis of Visualized Fluorescent Signals. TUNEL
63  2017 Differential Effects of CORM-2 and CORM-401 in Murine Intestinal Epithelial MODE-K Cells under Oxidative Stress. CO, IECs, NOX, ROS, TNF
64  2017 Heat shock exerts anticancer effects on liver cancer via autophagic degradation of aquaporin 5. AQP5, BafA1, IF, LC3B, WB
65  2017 Kaempferol Modulates DNA Methylation and Downregulates DNMT3B in Bladder Cancer. dDMPs, DNMTs, Kae
66  2017 Luteolin inhibits colorectal cancer cell epithelial-to-mesenchymal transition by suppressing CREB1 expression revealed by comparative proteomics study. cAMP, EMT
67  2017 Maternal RNA regulates Aurora C kinase during mouse oocyte maturation in a translation-independent fashion. AURKC, CPC, K-MT, Met I
68  2017 Novel Mutations in PRPF31 Causing Retinitis Pigmentosa Identified Using Whole-Exome Sequencing. GFP, GFP-PRPF31, GFP-PRPF31sg, PRPF31, RP, WES, WT
69  2017 p.Val19Glyfs*21 and p.Leu228* variants in the survival of motor neuron 1 trigger nonsense-mediated mRNA decay causing the SMN1 PTC+ transcripts degradation. FL, NMD, PTCs, SMA, SMN1
70  2017 Proteome analysis reveals an energy-dependent central process for Populuscanadensis seed germination. ABA
71  2017 Single-nucleotide substitution T to A in the polypyrimidine stretch at the splice acceptor site of intron 9 causes exon 10 skipping in the ACAT1 gene. NMD
72  2017 Stabilization of 4E-BP1 by PI3K kinase and its involvement in CHK2 phosphorylation in the cellular response to radiation. 4E-BPs, IR
73  2017 Synthesis and evaluation of modified chalcone based p53 stabilizing agents. ---
74  2017 The Deubiquitinating Enzyme USP14 Regulates Leukemic Chemotherapy Drugs-Induced Cell Apoptosis by Suppressing Ubiquitination of Aurora Kinase B. ---
75  2017 The duck enteritis virus early protein, UL13, found in both nucleus and cytoplasm, influences viral replication in cell culture. CHPK, DEV, GCV
76  2017 The ISG15-specific protease USP18 regulates stability of PTEN. DUB, ISG15, PTEN, RPPAs, USP18
77  2017 The ubiquitin ligase TRIM25 inhibits hepatocellular carcinoma progression by targeting metastasis associated 1 protein. HCC, MTA1
78  2017 TNF-alpha Induced the Enhanced Apoptosis of Mesenchymal Stem Cells in Ankylosing Spondylitis by Overexpressing TRAIL-R2. AS, AS, MSCs, TNF-alpha
79  2017 Zinc chloride rapidly stimulates efflux transporters in renal proximal tubules of killifish (Fundulus heteroclitus). BCRP, ETB, MRP2, mTOR, NOS, P-gp, PI3K, PKC, SGK1, TR
80  2016 Assessment of the Incidence of Posttreatment Endodontic Flare-ups in Patients undergoing Single-sitting Root Canal Therapies: A Clinical Study. EDTA
81  2016 Autophagy Plays a Protective Role in Tumor Necrosis Factor-alpha-Induced Apoptosis of Bone Marrow-Derived Mesenchymal Stem Cells. BECN1, BMSCs, LC3B, TNF-alpha
82  2016 Auxin flow-mediated competition between axillary buds to restore apical dominance. NPA, TIBA
83  2016 Curcumin inhibits HIV-1 by promoting Tat protein degradation. ---
84  2016 Cycloheximide Inhibits Actin Cytoskeletal Dynamics by Suppressing Signaling via RhoA. TGF-beta1
85  2016 DspA/E Contributes to Apoplastic Accumulation of ROS in Non-host A. thaliana. ROS, TEM
86  2016 Effect of anisomycin, a protein synthesis inhibitor, on the in vitro developmental potential, ploidy and embryo quality of bovine ICSI embryos. ANY, DMAP, ICM, ICSI, IVF, TE, TUNEL
87  2016 Ethanol attenuates vasorelaxation via inhibition of inducible nitric oxide synthase in rat artery exposed to interleukin-1beta. EtOH, IL, IM, iNOS, SMAs
88  2016 Giant seaperch iridovirus (GSIV) induces mitochondria-mediated cell death that is suppressed by bongkrekic acid and cycloheximide in a fish cell line. BKA, dpi, GSIV, PS
89  2016 Hairy and Groucho mediate the action of juvenile hormone receptor Methoprene-tolerant in gene repression. Gro, JH, Met, RNAi
90  2016 Heterocellular Contacts with Mouse Brain Endothelial Cells Via Laminin and alpha6beta1 Integrin Sustain Subventricular Zone (SVZ) Stem/Progenitor Cells Properties. BEC, NSCs, SVZ
91  2016 Identification of embryo proteins associated with seed germination and seedling establishment in germinating rice seeds. ---
92  2016 Methanolic leaf extract of Gymnema sylvestre augments glucose uptake and ameliorates insulin resistance by upregulating glucose transporter-4, peroxisome proliferator-activated receptor-gamma, adiponectin, and leptin levels in vitro. GLUT, MLGS, PPARgamma
93  2016 Overproduction of lactimidomycin by cross-overexpression of genes encoding Streptomyces antibiotic regulatory proteins. iso-MGS, LTM, SARPs
94  2016 Regulation and the Mechanism of Estrogen on Cav1.2 Gene in Rat-Cultured Cortical Astrocytes. ActD, DPN, ER, LTCC, PPT
95  2016 Regulation of Apoptosis by miR-122 in Pterygium via Targeting Bcl-w. mi, miR-122
96  2016 Rex Rabbit Somatic Cell Nuclear Transfer with In Vitro-Matured Oocytes. 6-DMAP, CCs, FFCs, GV, IVC, SCNT, SFCs
97  2016 Smac mimetic with TNF-alpha targets Pim-1 isoforms and reactive oxygen species production to abrogate transformation from blebbishields. FasL, ROS, TNF-alpha
98  2016 Sulforaphane increases the efficacy of anti-androgens by rapidly decreasing androgen receptor levels in prostate cancer cells. ADT, AR, BIC, CFUs, CRPC, ENZ, PCa, PSA, SFN
99  2016 The protein level and transcription activity of activating transcription factor 1 is regulated by prolyl isomerase Pin1 in nasopharyngeal carcinoma progression. ATF1, NPC
100  2016 WNK3 Kinase Enhances the Sodium Chloride Cotransporter Expression via an ERK 1/2 Signaling Pathway. ---