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Abbreviation : CRD
Long Form : colorectal distension
No. Year Title Co-occurring Abbreviation
2020 Attenuation of Visceral and Somatic Nociception by Ghrelin Mimetics. VMR
2020 Blockade of BDNF signalling attenuates chronic visceral hypersensitivity in an IBS-like rat model. AMPAR, BDNF, EMG, IBS, NMS, PKMzeta, SDH, sEPSCs, TrkB
2020 Chain length of dietary fatty acids determines gastrointestinal motility and visceromotor function in mice in a fatty acid binding protein 4-dependent manner. BW, FABP4, FAs, GI, LCFAs, MCFAs, STD, VMR
2020 Disinhibition of PVN-projecting GABAergic neurons in AV region in BNST participates in visceral hypersensitivity in rats. AV, BNST, CRH, ELS, PVN, sIPSC
2020 Lactobacillus plantarum PS128 Ameliorated Visceral Hypersensitivity in Rats Through the Gut-Brain Axis. 5-HTP, IBS, VH
2020 Paradoxical effects of continuous high dose gabapentin treatment on autonomic dysreflexia after complete spinal cord injury. AD, GBP, SCI
2020 [Effect of electroacupuncture of "Hegu" (LI4) and "Zusanli" (ST36) on intestinal sensitivity and motility in irritable bowel syndrome rats]. 5-HT3AR, AWR, EA, IBS
2019 Activating metabotropic glutamate receptor‑7 attenuates visceral hypersensitivity in neonatal maternally separated rats. IBS, mGluR7, NF, NMS
2019 Activation of cannabinoid 2 receptor relieves colonic hypermotility in a rat model of irritable bowel syndrome. CB2, FWC, GI, IBS, ITT, NO, VMR, WAS
10  2019 Brain corticotropin-releasing factor signaling: Involvement in acute stress-induced visceral analgesia in male rats. i.c.v, SIVA, VMR, WAS
11  2019 Decreased miR-325-5p Contributes to Visceral Hypersensitivity Through Post-transcriptional Upregulation of CCL2 in Rat Dorsal Root Ganglia. CCL2, DRGs, NCI
12  2019 Depression Promotes the Onset of Irritable Bowel Syndrome through Unique Dysbiosis in Rats. IBS, PTSD
13  2019 Development of a decerebrate model for investigating mechanisms mediating viscero-sympathetic reflexes in the spinalized rat. AD, HR, MAP, RSNA, SCI
14  2019 Development of Cardiovascular Dysfunction in a Rat Spinal Cord Crush Model and Responses to Serotonergic Interventions. AD, DA, DOI, HR, i.t, MAP, s.c, SCI
15  2019 Distinct roles of angiotensin receptors in autonomic dysreflexia following high-level spinal cord injury in mice. AD, Ang, HR, MAP, RAS, SCI
16  2019 Effect of moxibustion on the expression of GDNF and its receptor GFRalpha3 in the colon and spinal cord of rats with irritable bowel syndrome. AWR, IBS
17  2019 Effects of Deoxyschisandrin on Visceral Sensitivity of Mice with Inflammatory Bowel Disease. AWR, BDNF, DAI
18  2019 Electroacupuncture Alleviated Referral Hindpaw Hyperalgesia via Suppressing Spinal Long-Term Potentiation (LTP) in TNBS-Induced Colitis Rats. CFEFP, EA, IBS, LTP, VMR
19  2019 EphrinB2/ephB2-mediated myenteric synaptic plasticity: mechanisms underlying the persistent muscle hypercontractility and pain in postinfectious IBS. arc, c-fos, IBS, p.i
20  2019 Exploring the Potential of RET Kinase Inhibition for Irritable Bowel Syndrome: A Preclinical Investigation in Rodent Models of Colonic Hypersensitivity. IBS, RET
21  2019 Hydrogen sulfide downregulates colonic afferent sensitivity by a nitric oxide synthase-dependent mechanism in mice. AWR
22  2019 Inhibition of electroacupuncture on nociceptive responses of dorsal horn neurons evoked by noxious colorectal distention in an intensity-dependent manner. EA, WDR
23  2019 Invivo evaluation of post-operative pain reduction on rat model after implantation of intraperitoneal PET meshes functionalised with cyclodextrins and loaded with ropivacaine. ---
24  2019 Mas-related G protein-coupled receptor C11 (Mrgprc11) induces visceral hypersensitivity in the mouse colon: A novel target in gut nociception? Mrgprc11
25  2019 Sex differences in insular functional connectivity in response to noxious visceral stimulation in rats. A-P, FC, INS, ROIs
26  2019 Systemic administration of serotonin exacerbates abdominal pain and colitis via interaction with the endocannabinoid system. AEA, CB, NAPE-PLD
27  2019 The comprehensive pathophysiological changes in a novel rat model of postinflammatory visceral hypersensitivity. 5-HT, 5-HT3AR, CRHR, CUMS, IBS, TNBS, VH
28  2019 Tong-Xie-Yao-Fang improves intestinal permeability in diarrhoea-predominant irritable bowel syndrome rats by inhibiting the NF-kappaB and notch signalling pathways. CECs, ELISAs, FWC, HE, IBS-D, TXYF
29  2019 Vagal Transient Receptor Potential Ankyrin 1 Mediates Stress-exacerbated Visceral Mechanonociception After Antral Cold Exposure. IBS-D, VMR
30  2018 A rat model for studying electroacupuncture analgesia on acute visceral hyperalgesia. AA, AWR, EA, EMG
31  2018 Adherent-Invasive E. coli enhances colonic hypersensitivity and P2X receptors expression during post-infectious period. AIEC, CD, CHS, IBD, IBS, VMR
32  2018 Bifidobacterium longum and Lactobacillus helveticus Synergistically Suppress Stress-related Visceral Hypersensitivity Through Hypothalamic-Pituitary-Adrenal Axis Modulation. HPA, IBS
33  2018 Blockage of High-Affinity Choline Transporter Increases Visceral Hypersensitivity in Rats with Chronic Stress. AWR, DRGs, HC-3, WAS
34  2018 Colitis-induced alterations in response properties of visceral nociceptive neurons in the rat caudal medulla oblongata and their modulation by 5-HT3 receptor blockade. CVLM, NTS
35  2018 Colonic Hypermotility in a Rat Model of Irritable Bowel Syndrome Is Associated with Upregulation of TMEM16A in Myenteric Plexus. CaCC, FWC, IBS, ITT, MP, NFA, VMR, WAS
36  2018 Electroacupuncture Inhibits Visceral Nociception via Somatovisceral Interaction at Subnucleus Reticularis Dorsalis Neurons in the Rat Medulla. EA, SRD
37  2018 Gut microbiota was modulated by moxibustion stimulation in rats with irritable bowel syndrome. AWR, BTVC, EA, IBS, PB
38  2018 Involvement of dopamine system in the regulation of the brain corticotropin-releasing hormone in paraventricular nucleus in a rat model of chronic visceral pain. AWR, CRH, PVN, SD, VTA
39  2018 Linaclotide Attenuates Visceral Organ Crosstalk: Role of Guanylate Cyclase-C Activation in Reversing Bladder-Colon Cross-Sensitization. BPS, GCC, IBS, IBS-C, PS, TEER
40  2018 Opioid Receptors Contribute to Antinociceptive Effect of Tianeptine on Colorectal Distension-Induced Visceral Pain in Rats. NLX, NLXM
41  2018 Oxytocin inhibited stress induced visceral hypersensitivity, enteric glial cells activation, and release of proinflammatory cytokines in maternal separated rats. CNS, EGCs, GFAP, GI, IBS, MS, OT, PBS, TLR, VH, VMR, WAS
42  2018 Pharmacological modulation of colorectal distension evoked potentials in conscious rats. CEP
43  2018 Protective effect and mechanism of injection of glutamate into cerebellum fastigial nucleus on chronic visceral hypersensitivity in rats. 3-MPA, AWR, BIC, CVH, EMG, FN, Glu, LHA
44  2018 Rapamycin Exacerbates Cardiovascular Dysfunction after Complete High-Thoracic Spinal Cord Injury. AD, mTOR, RAP, SCI
45  2018 Roles of noradrenergic transmission within the ventral part of the bed nucleus of the stria terminalis in bidirectional brain-intestine interactions. BNST, GI, vBNST
46  2018 Small-Conductance Ca2+-Activated K+ Channel 2 in the Dorsal Horn of Spinal Cord Participates in Visceral Hypersensitivity in Rats. DH
47  2018 The central effects of buspirone on abdominal pain in rats. 5-HT1a R, VLM
48  2018 Upregulation of the high-affinity choline transporter in colon relieves stress-induced hyperalgesia. ACh, AWR, IBS, VMR, WAS
49  2018 [Electroacupuncture Relieves Visceral Hypersensitivity by Down-regulating Mast Cell Number,PAR-2/TRPV 1 Signaling, etc. in Colonic Tissue of Rats with Irritable Bowel Syndrome]. AWR, CGRP, EA, IBS, PAR2, Try
50  2017 alpha-Conotoxin Vc1.1 inhibits human dorsal root ganglion neuroexcitability and mouse colonic nociception via GABAB receptors. CVH, CVP, DRG, GABABR
51  2017 Alpha-lipoic Acid suppresses P2X receptor activities and visceral hypersensitivity to colorectal distention in diabetic rats. ALA, AWR, DRG, STZ
52  2017 Altered intrinsic and synaptic properties of lumbosacral dorsal horn neurons in a mouse model of colitis. SDH, SDH
53  2017 Ameliorative effect of chlorpromazine hydrochloride on visceral hypersensitivity in rats: possible involvement of 5-HT2A receptor. IBS
54  2017 Aminophylline suppresses stress-induced visceral hypersensitivity and defecation in irritable bowel syndrome. ARs, IBS, IBS-D, PDEs, WRS
55  2017 Analgesic effect of ADX71441, a positive allosteric modulator (PAM) of GABAB receptor in a rat model of bladder pain. CMG, GERD, i.c.v, i.t, LS, OAB, PAM, PNA, UBD, VMR
56  2017 Antinociceptive Effect of Ghrelin in a Rat Model of Irritable Bowel Syndrome Involves TRPV1/Opioid Systems. AWR, DRG, GHS-R1alpha, IBS, MD, qRT-PCR, TRPV1
57  2017 Downregulation of the spinal NMDA receptor NR2B subunit during electro-acupuncture relief of chronic visceral hyperalgesia. AWR, EA, EA, IBS, NMDA
58  2017 Luminal contents from the gut of colicky infants induce visceral hypersensitivity in mice. EMG, FS
59  2017 Mu and delta opioid receptor knockout mice show increased colonic sensitivity. DSS, KO, Penk
60  2017 Neonatal Maternal Deprivation Enhances Presynaptic P2X7 Receptor Transmission in Insular Cortex in an Adult Rat Model of Visceral Hypersensitivity. IC, mEPSC, NMD, P2X7Rs, sEPSC
61  2017 P2X3 receptor-mediated visceral hyperalgesia and neuronal sensitization following exposure to PTSD-like stress in the dorsal root ganglia of rats. AWR, DRG, PTSD, SPS, VMR
62  2017 Probiotics reduce repeated water avoidance stress-induced colonic microinflammation in Wistar rats in a sex-specific manner. IFNR, IL, RT-PCR, rWAS, TNFA, VMR
63  2017 Prokinetic effects of LD02GIFRO on functional gastrointestinal disorder in rats. GIT, POI, VMR
64  2017 Regulation of transient receptor potential cation channel subfamily V1 protein synthesis by the phosphoinositide 3-kinase/Akt pathway in colonic hypersensitivity. 4E-BP, DRG, NGF, PI3K, TRPV1, VR1
65  2017 Toll-Like Receptor 4 in Paraventricular Nucleus Mediates Visceral Hypersensitivity Induced by Maternal Separation. CRF, CRFR1, MS, PVN, TLR4
66  2016 Activation of corticotropin-releasing factor neurons and microglia in paraventricular nucleus precipitates visceral hypersensitivity induced by colorectal distension in rats. CRDs, CRF, IL-1beta, MyD88, NF-kappaB, PVN, TLR4, TNF-alpha
67  2016 Changes in mast cell infiltration: a possible mechanism in detrusor overactivity induced by visceral hypersensitivity. AWR, DO, MC, VH
68  2016 Colonic mucosal N-methyl-D-aspartate receptor mediated visceral hypersensitivity in a mouse model of irritable bowel syndrome. AWR, IBS, NMDAR, TNBS
69  2016 Comparative effects of alpha2delta-1 ligands in mouse models of colonic hypersensitivity. CHS, DSS, NH, NMS, VMR
70  2016 Comparison of Electroacupuncture and Moxibustion for Relieving Visceral Hypersensitivity in Rats with Constipation-Predominant Irritable Bowel Syndrome. AWR, C-IBS, EA, MC, Mox
71  2016 Early life stress elicits visceral hyperalgesia and functional reorganization of pain circuits in adult rats. ELS, ELS, EMG, LC/LPB
72  2016 Effect of estrogen on visceral sensory function in a non-inflammatory colonic hypersensitivity rat model. BUT, Sham-P, VMR
73  2016 Effect of nonsteroidal anti-inflammatory drugs on colorectal distension-induced visceral pain. i.p, VMR
74  2016 Electroacupuncture analgesia with different frequencies is mediated via different opioid pathways in acute visceral hyperalgesia rats. AA, AWR, EA, EMGs
75  2016 Elevated H2 O2 levels in trinitrobenzene sulfate-induced colitis rats contributes to visceral hyperalgesia through interaction with the transient receptor potential ankyrin 1 cation channel. TNBS, TRPA1, VMR
76  2016 Estrous cycle influences excitatory amino acid transport and visceral pain sensitivity in the rat: effects of early-life stress. ACC, EAATs, ELS, MS, NS
77  2016 Gender-related differential effect of tachykinin NK2 receptor-mediated visceral hyperalgesia in guinea pig colon. ---
78  2016 In vivo characterization of colorectal and cutaneous inputs to lumbosacral dorsal horn neurons in the mouse spinal cord. SDH
79  2016 Neonatal maternal separation increases susceptibility to experimental colitis and acute stress exposure in male mice. CRF, MPO, NMS, TNBS, VMR, WAS
80  2016 Repeated Water Avoidance Stress Alters Mucosal Mast Cell Counts, Interleukin-1beta Levels with Sex Differences in the Distal Colon of Wistar Rats. rWAS, VMR
81  2016 Role of transient receptor potential melastatin 2 (TRPM2) channels in visceral nociception and hypersensitivity. DRG, TRPM2, VMR
82  2016 Zeta Inhibitory Peptide as a Novel Therapy to Control Chronic Visceral Hypersensitivity in a Rat Model. EMG, IBS, NMS, p-PKMzeta, PKMzeta, ZIP
83  2016 [Effect of Electroacupuncture and Moxibustion on Visceral Pain and Expression of VR 1 and HSP 70 of "Tianshu" (ST 25) Region in Colorectal Distension-induced Visceral Hypersensitivity Rats]. AWR, EA, HSP, Moxi, VHS, VR 1
84  2016 [Expression profiles of brain-derived neurotrophic factor in the spinal dorsal horn of young rats with visceral hypersensitivity]. BDNF, IHS, NMS
85  2015 Activation of p38 MAPK in the rostral ventromedial medulla by visceral noxious inputs transmitted via the dorsal columns may contribute to pelvic organ cross-sensitization in rats with endometriosis. AWR, DC, MAPK, RVM
86  2015 Acute sacral nerve stimulation reduces visceral mechanosensitivity in Rat through spinal opioid pathway. MOR, SNS
87  2015 Colorectal distention induces acute and delayed visceral hypersensitivity: role of peripheral corticotropin-releasing factor and interleukin-1 in rats. VMR
88  2015 Corticotrophin-releasing factor 1 activation in the central amygdale and visceral hyperalgesia. CeA, CRF
89  2015 Differential Contribution of TRPA1, TRPV4 and TRPM8 to Colonic Nociception in Mice. TRP, VMR, WT
90  2015 Effect of electroacupuncture on P2X3 receptor regulation in the peripheral and central nervous systems of rats with visceral pain caused by irritable bowel syndrome. AWR, DRG, EA, HANS, IBS, mRNA, SD
91  2015 Function of Nucleus Ventralis Posterior Lateralis Thalami in Acupoint Sensitization Phenomena. EA, VPL
92  2015 Impairments of the primary afferent nerves in a rat model of diabetic visceral hyposensitivity. CGRP, GI, PGP
93  2015 Increased VGLUT3 involved in visceral hyperalgesia in a rat model of irritable bowel syndrome. ACRS, MCs, p.i, VGLUT3
94  2015 Inhibitory effects of SKI3246, the rhizome extract of Atractylodes japonica, on visceral hypersensitivity in experimental irritable bowel syndrome rat models. AWR
95  2015 Injection of corticotropin-releasing hormone into the amygdala aggravates visceral nociception and induces noradrenaline release in rats. CeA, CRH
96  2015 Role of the potassium chloride cotransporter isoform 2-mediated spinal chloride homeostasis in a rat model of visceral hypersensitivity. CCC, IBS, KCC2, WAS
97  2015 The effect of FAAH, MAGL, and Dual FAAH/MAGL inhibition on inflammatory and colorectal distension-induced visceral pain models in Rodents. FAAH, MAGL, VMR
98  2015 The inhibitory effect of granisetron on ventrolateral medulla neuron responses to colorectal distension in rats. IBS, VLM
99  2015 The roles of neurotensin and its analogues in pain. BBB, NT, NTS1, NTS2, PAG, RVM, SIAN
100  2015 Vagal afferent-dependent cholecystokinin modulation of visceral pain requires central amygdala NMDA-NR2B receptors in rats. CCK, CeA, NMDA, siRNA, VMR