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Abbreviation : CRHR1
Long Form : corticotropin-releasing hormone receptor 1
No. Year Title Co-occurring Abbreviation
2022 Auricular Vagus Nerve Stimulation Ameliorates Functional Dyspepsia with Depressive-Like Behavior and Inhibits the Hypothalamus-Pituitary-Adrenal Axis in a Rat Model. ACTH, aVNS, CRF, FD
2022 Genetic Variants Associated With Resilience in Human and Animal Studies. APOE, BDNF, COMT, FKBP5, OPRM1, OXTR
2022 LncRNA NEAT1 Inhibits Neuronal Apoptosis and Induces Neuronal Viability of Depressed Rats Via microRNA-320-3p/CRHR1 Axis. CORT, miR, NEAT1
2022 Social Isolation Stress Modulates Pregnancy Outcomes and the Inflammatory Profile of Rat Uterus. IL, MG, PTB, SIS, TG
2022 The role of maternal exercise on placental, behavioral and genetic alterations induced by prenatal stress. 5-HT1AR, BDNF I, CON, GR, MR, OXTr1, PNS
2021 Heat stress affects fetal brain and intestinal function associated with the alterations of placental barrier in late pregnant mouse. CD36, DGAT2, HS, HSD11B2, hsp90b1, Htr1d, hyou1, TC, TG, TN
2021 Prenatally traumatized mice reveal hippocampal methylation and expression changes of the stress-related genes Crhr1 and Fkbp5. dHPC, FKBP5, PT
2021 The role of rs242941, rs1876828, rs242939 and rs110402 polymorphisms of CRHR1 gene and the depression: systematic review and meta-analysis. ---
2020 Aneurysmal subarachnoid haemorrhage: effect of CRHR1 genotype on fatigue and depression. aSAH, SNPs
10  2020 Aneurysmal subarachnoid haemorrhage: Effect of CRHR1 genotype on mental health-related quality of life. aSAH, QoL
11  2020 Bioelectronic sensor mimicking the human neuroendocrine system for the detection of hypothalamic-pituitary-adrenal axis hormones in human blood. ACTH, CNTFET, CRH, HPA, MC2R, ND
12  2020 Chronic stress impairs male spermatogenesis function and Nectin-3 protein expression in the testis. CRH
13  2020 Gene-environment interactions between HPA-axis genes and childhood maltreatment in depression: a systematic review. ACE, AVP, CM, CRH, CRHR2, FKBP5, HPA axis, NR3C1, NR3C2
14  2020 Hypothalamic-pituitary-adrenal axis suppression in asthma: A glucocorticoid receptor polymorphism may protect. HPAS, SNPs
15  2020 Lack of association of common polymorphisms linked to empathic behavior with self-reported trait empathy in healthy volunteers. COMT, IRI, OXTR
16  2020 Sex- and Brain Region-specific Changes in Gene Expression in Male and Female Rats as Consequences of Methamphetamine Self-administration and Abstinence. Crhr2, Hcrtr1, HCRTR2, HIP, METH SA, Oprk1, PDYN, PFC
17  2020 Short treatment with antalarmin alters adrenal gland receptors in the rat model of endometriosis. HPA
18  2020 The Neuropeptide System and Colorectal Cancer Liver Metastases: Mechanisms and Management. CGRP, CRC, LM, NPY, NT, Nts, SP, VIP
19  2019 A Candidate Gene Association Study of FKBP5 and CRHR1 Polymorphisms in Relation to War-Related Posttraumatic Stress Disorder. BSI, CAPS, FKBP5, MINI, PTSD, SEE
20  2019 Assessing real-time signaling and agonist-induced CRHR1 internalization by optical methods. FRET
21  2019 Association of Corticotropin-Releasing Hormone Receptor-1 Gene Polymorphisms and Personality Traits with Violent Aggression in Male Adolescents. SNP, SSP
22  2019 Cancer-Specific Loss of Urocortin3 in Human Renal Cancer. CRH, CRHBP, RCC, UCN3
23  2019 Crosstalk of BMP-4 and RA signaling pathways on Pomc gene regulation in corticotrophs. BMP4, POMC, RA
24  2019 Effects of maternal separation on serotonergic systems in the dorsal and median raphe nuclei of adult male Tph2-deficient mice. ---
25  2019 Exchange protein directly activated by cAMP 2 is required for corticotropin-releasing hormone-mediated spine loss. ---
26  2019 Gene-environment interactions between HPA-axis genes and stressful life events in depression: a systematic review. ACE, AVP, CRH, CRHR2, FKBP5, GE, HPA axis, NR3C1, NR3C2, SLEs, SNPs
27  2019 Genome-wide Association Study of Maximum Habitual Alcohol Intake in >140,000 U.S. European and African American Veterans Yields Novel Risk Loci. ---
28  2019 Interactive effects of corticotropin-releasing hormone receptor 1 gene and work stress on burnout in medical professionals in a Chinese Han population. HPA
29  2019 The effects of childhood maltreatment on epigenetic regulation of stress-response associated genes: an intergenerational approach. CM, FKBP5
30  2018 A fluorescence nanoscopy marker for corticotropin-releasing hormone type 1 receptor: computer design, synthesis, signaling effects, super-resolved fluorescence imaging, and in situ affinity constant in cells. GPCRs, STORM
31  2018 Family environment interacts with CRHR1 rs17689918 to predict mental health and behavioral outcomes. ECPBHS
32  2018 Genes involved in stress response influence lithium efficacy in bipolar patients. ACP1, Avpr1b, BAG-1, DUSP1, GLCC1, HPA, SRSF, STIP1
33  2018 Genetic association of human Corticotropin-Releasing Hormone Receptor 1 (CRHR1) with Internet gaming addiction in Korean male adolescents. IGA
34  2018 HPA-axis genes as potential risk variants for neurocognitive decline in trauma-exposed, HIV-positive females. CRHBP, HPA, NCI, SNPs
35  2018 Influence of CRHR1 Polymorphisms and Childhood Abuse on Suicide Attempts in Affective Disorders: A GxE Approach. HPA axis, SNPs
36  2018 Interactive effects of prenatal alcohol exposure and chronic stress in adulthood on anxiety-like behavior and central stress-related receptor mRNA expression: Sex- and time-dependent effects. CUS, GR, HPA, mPFC, MR, PAE, PF
37  2018 Low resilience to stress is associated with candidate gene expression alterations in the dopaminergic signalling pathway. BDNF, DAT, DBH, DDC, DRD1, DRD2, DRD3, DRD4, DRD5, GDNF, MAOM, TH
38  2018 Placebo Effects Across Self-Report, Clinician Rating, and Objective Performance Tasks Among Women With Post-Traumatic Stress Disorder: Investigation of Placebo Response in a Pharmacological Treatment Study of Post-Traumatic Stress Disorder. PTSD
39  2018 Possible mechanisms of prenatal cold stress induced-anxiety-like behavior depression in offspring rats. BDNF, DA, GABAB2, GFAP, GR, HPA, IGF1R, MR, NE, NeuN
40  2018 Role of HPA and the HPG Axis Interaction in Testosterone-Mediated Learned Helpless Behavior. AR, ChIP, CRH, CRHR2, ERbeta, FKBP5, HPA, HPG, LH, TC
41  2018 Sevoflurane-induced learning deficits and spine loss via nectin-1/corticotrophin-releasing hormone receptor type 1 signaling. ---
42  2017 cAMP-dependent cell differentiation triggered by activated CRHR1 in hippocampal neuronal cells. CRH, GPCR, sAC, tmACs
43  2017 CRHR1 exacerbates the glial inflammatory response and alters BDNF/TrkB/pCREB signaling in a rat model of global cerebral ischemia: implications for neuroprotection and cognitive recovery. ANT, BDNF, IR, NeuN, TrkB
44  2017 CRHR1 promoter hypomethylation: An epigenetic readout of panic disorder? BAI
45  2017 DNA methylation and expression of stress related genes in PBMC of MDD patients with and without serious suicidal ideation. BDNF, CRHBP, FKBP5, MDD, NR3C1, PBMC
46  2017 Effects of crack cocaine addiction and stress-related genes on peripheral BDNF levels. BDNF
47  2017 Effects of genetic factors to inhaled corticosteroid response in children with asthma: a literature review. DUSP1, GLCCI1, ICS, NR3C1, ORMDL3, STIP1, TBX21, VEGF
48  2017 Epigenetic Changes in the CRH Gene are Related to Severity of Suicide Attempt and a General Psychiatric Risk Score in Adolescents. CRH, CRHBP, CRHR2, FKBP5, HPA
49  2017 Hypothalamo‑hypophysial system in rats with autotransplantation of the adrenal cortex. ---
50  2017 Methylation of HPA axis related genes in men with hypersexual disorder. CRH, CRHBP, CRHR2, HD, HPA
51  2017 miR-34b attenuates trauma-induced anxiety-like behavior by targeting CRHR1. HPA, PVN
52  2017 Peri-adolescent asthma symptoms cause adult anxiety-related behavior and neurobiological processes in mice. SERT
53  2017 Sex-specific gene-environment interactions underlying ASD-like behaviors. ASDs, CNTNAP2
54  2017 The behavioral and molecular evaluation of effects of social instability stress as a model of stress-related disorders in adult female rats. CON, CSIS, OXTR, PFC, POMC
55  2016 Corticotropin-releasing hormone receptor 1 (CRH-R1) polymorphisms are associated with irritable bowel syndrome and acoustic startle response. ASR, GI, HCs, IBS
56  2016 Different cAMP sources are critically involved in G protein-coupled receptor CRHR1 signaling. cAMP, sAC, tmACs
57  2016 Effects of corticotropin-releasing hormone receptor 1 SNPs on major depressive disorder are influenced by sex and smoking status. MDD
58  2016 Genetic associations of the response to inhaled corticosteroids in children during an asthma exacerbation. ICSs, TBX21
59  2016 Genome-wide analysis of over 106 000 individuals identifies 9 neuroticism-associated loci. CELF4, EPQR-S, GRIK3, GWAS, KLHL2, MAPT, MDD, QIMR
60  2016 Hsa-miR-34a mediated repression of corticotrophin releasing hormone receptor 1 regulates pro-opiomelanocortin expression in patients with complex regional pain syndrome. BMI, CRH, CRPS, POMC
61  2016 The sex-dependent role of the glucocorticoid receptor in depression: variations in the NR3C1 gene are associated with major depressive disorder in women but not in men. FKBP5, GR, MDD, MR, SNPs
62  2015 Corticotropin-Releasing Hormone Receptor Type 1 (CRHR1) Clustering with MAGUKs Is Mediated via Its C-Terminal PDZ Binding Motif. MAGI2, MAGUK, PSD-95, SAP97
63  2015 CRHBP polymorphisms predict chronic pain development following motor vehicle collision. CRHBP, HPA, MSP, MVC
64  2015 CRHR1 Gene SNPs and Response to Systemic Corticosteroids in Indian Asthmatic Children During Acute Exacerbation. CNR, CR, SNPs
65  2015 Epidemiological support for genetic variability at hypothalamic-pituitary-adrenal axis and serotonergic system as risk factors for major depression. HTR2A, MDD, SNPs, TPH1
66  2015 Ethnic-specific genetic association of variants in the corticotropin-releasing hormone receptor 1 gene with nicotine dependence. AA, EA, FTND, HSI, SNPs, SQ
67  2015 Family Economic Hardship, Corticotropin-Releasing Hormone Receptor Polymorphisms, and Depressive Symptoms in Rural African-American Youths. ---
68  2015 Genetic moderation of interpersonal psychotherapy efficacy for low-income mothers with major depressive disorder: implications for differential susceptibility. IPT
69  2015 Human fear acquisition deficits in relation to genetic variants of the corticotropin-releasing hormone receptor 1 and the serotonin transporter--revisited. ---
70  2015 Investigating the role of early childhood abuse and HPA axis genes in suicide attempters with bipolar disorder. HPA
71  2015 Programming of stress-related behavior and epigenetic neural gene regulation in mice offspring through maternal exposure to predator odor. BDNF, CORT
72  2015 Serotonergic systems in the balance: CRHR1 and CRHR2 differentially control stress-induced serotonin synthesis. 5-HTP, DR, PnC
73  2014 A novel genotyping method for detection of the CRHR1 (rs1396862: C>T) gene variation among North Indian population. ---
74  2014 Bidirectional rescue of extreme genetic predispositions to anxiety: impact of CRH receptor 1 as epigenetic plasticity gene in the amygdala. BLA, YY1
75  2014 Blockade of corticotropin-releasing hormone receptor 1 attenuates early-life stress-induced synaptic abnormalities in the neonatal hippocampus. GRs
76  2014 Blunted HPA axis reactivity reveals glucocorticoid system dysbalance in a mouse model of high anxiety-related behavior. CORT, HPA
77  2014 Environmental manipulations generate bidirectional shifts in both behavior and gene regulation in a crossbred mouse model of extremes in trait anxiety. CMS, EE, HAB, Hmgn3
78  2014 Genetic moderation of child maltreatment effects on depression and internalizing symptoms by serotonin transporter linked polymorphic region (5-HTTLPR), brain-derived neurotrophic factor (BDNF), norepinephrine transporter (NET), and corticotropin releasing hormone receptor 1 (CRHR1) genes in African American children. BDNF, GE, NET
79  2014 Histone modifications of the Crhr1 gene in a rat model of depression following chronic stress. CRH, CUMS, HPA
80  2014 Indirect effect of corticotropin-releasing hormone receptor 1 gene variation on negative emotionality and alcohol use via right ventrolateral prefrontal cortex. rVLPFC
81  2014 Influence of genetic polymorphisms involved in the hypothalamic-pituitary-adrenal axis and their interactions with environmental factors on antidepressant response. CTQ-SF, SNPs
82  2014 Variation in the corticotropin-releasing hormone receptor 1 (CRHR1) gene modulates age effects on working memory. CRH, WM
83  2013 Association of CRHR1 variants and posttraumatic stress symptoms in hurricane exposed adults. EA, HPA, PTSD, SNPs
84  2013 Association of glucocorticoid and type 1 corticotropin-releasing hormone receptors gene variants and risk for depression during pregnancy and post-partum. EPDS, HPA, PND, SNPs
85  2013 Family-based study of AVPR1B association and interaction with stressful life events on depression and anxiety in suicide attempts. ACTH, AVPR1B, SA, SLEs, SNPs
86  2013 HPA axis genetic variation, cortisol and psychosis in major depression. GR, HCs, HPA, NPMD, PMD
87  2013 Influence of social environment on loneliness in older adults: Moderation by polymorphism in the CRHR1. ---
88  2013 Nectin-3 links CRHR1 signaling to stress-induced memory deficits and spine loss. CRH
89  2013 Negative life events and corticotropin-releasing-hormone receptor1 gene in recurrent major depressive disorder. MDD
90  2013 The CRHR1 gene contributes to genetic susceptibility of aggressive behavior towards others in Chinese southwest Han population. HPA, iMLDR, SNPs
91  2013 [Expression of corticotropin-releasing hormone receptor type-1 in intrahepatic cholestatic placental tissue]. ICP
92  2012 Association of hypothalamic-pituitary-adrenal axis-related polymorphisms with stress in asthmatic children on inhaled corticosteroids. GR, HPA, ICS, MC2R, SNPs
93  2012 Depression and anxiety symptoms among women who carry the FMR1 premutation: impact of raising a child with fragile X syndrome is moderated by CRHR1 polymorphisms. CES-D, FXS, PANAS, SNPs, SPAI, STAI
94  2012 Genotyping the CRHR1 rs242939 (A>G) polymorphism by a one-step tetra primer-amplification refractory mutation system-polymerase chain reaction. RFLP, SNPs, T-ARMS-PCR
95  2012 Interactive effects of corticotropin-releasing hormone receptor 1 gene and childhood adversity on depressive symptoms in young adults: findings from a longitudinal study. ---
96  2012 Pharmacogenetic investigation of response to duloxetine treatment in generalized anxiety disorder. DRD3, GAD, MDD, PDE1A, SNPs
97  2012 Transgenerational effects of early experience on behavioral, hormonal and gene expression responses to acute stress in the precocial chicken. Egr-1, HPA
98  2012 Upregulation of PVN CRHR1 by gestational intermittent hypoxia selectively triggers a male-specific anxiogenic effect in rat offspring. EPM, GIH, OF, PVN
99  2012 Variation in the corticotropin-releasing hormone receptor 1 (CRHR1) gene influences fMRI signal responses during emotional stimulus processing. BOLD, CRH, MDD
100  2011 A CRHR1 haplotype moderates the effect of adverse childhood experiences on lifetime risk of major depressive episode in African-American women. AAs, ACEs, AD, EAs, MDE