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Abbreviation : Cas9
Long Form : CRISPR-associated protein 9
No. Year Title Co-occurring Abbreviation
2020 A biotechnology-based male-sterility system for hybrid seed production in tomato. CRISPR
2020 A CRISPR-Cas9 system for multiple genome editing and pathway assembly in Candida tropicalis. CRISPR
2020 A Single "All-in-One" Helper-Dependent Adenovirus to Deliver Donor DNA and CRISPR/Cas9 for Efficient Homology-Directed Repair. gRNA, HDAd, iPSCs
2020 Anti-RDL and Anti-mGlutR1 Receptors Antibody Testing in Honeybee Brain Sections using CRISPR-Cas9. CRISPR, RDL
2020 Application and prospects of CRISPR/Cas9-based methods to trace defined genomic sequences in living and fixed plant cells. CRISPR, TALE, ZFP
2020 Base Editing: The Ever Expanding Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) Tool Kit for Precise Genome Editing in Plants. CRISPR
2020 CRISPR-PCD and CRISPR-PCRep: Two novel technologies for simultaneous multiple segmental chromosomal deletion/replacement in Saccharomyces cerevisiae. CRISPR
2020 CRISPR/Cas9 mediated GFP-Human Dentin Matrix Protein 1 (DMP1) Promoter knock-in at the ROSA26 locus in mesenchymal stem cell for monitoring osteoblast differentiation. CRISPR, DMP1, MSCs
2020 Designing Safer CRISPR/Cas9 Therapeutics for HIV: Defining Factors That Regulate and Technologies Used to Detect Off-Target Editing. BLISS, CIRCLE-seq, CRISPR, DISCOVER-Seq, DSB, GUIDE-Seq, HIV-1, NGS, WGS
10  2020 Disruption of miRNA sequences by TALENs and CRISPR/Cas9 induces varied lengths of miRNA production. CRISPR, miRNAs, nt, SAM
11  2020 Disruption of mosGILT in Anopheles gambiae impairs ovarian development and Plasmodium infection. mosGILT, TEP1, Vg
12  2020 Effect of CRISPR/Cas9-Mediated PD-1-Disrupted Primary Human Third-Generation CAR-T Cells Targeting EGFRvIII on In Vitro Human Glioblastoma Cell Growth. CAR, CRISPR, EvCAR-T, GBM
13  2020 Efficient genome editing in the olive fruit fly, Bactrocera oleae. CRISPR
14  2020 Engineering abiotic stress tolerance via CRISPR/ Cas-mediated genome editing. CRISPR
15  2020 Exploring alternative catalytic mechanisms of the Cas9 HNH domain. ---
16  2020 Facilitating gene editing in potato: a Single-Nucleotide Polymorphism (SNP) map of the Solanum tuberosum L. cv. Desiree genome. CRISPR, DM, SNP
17  2020 Fusion of the Cas9 endonuclease and the VirD2 relaxase facilitates homology-directed repair for precise genome engineering in rice. Cas9-VirD2, CRISPR, DSBs, HDR
18  2020 Generalizable sgRNA design for improved CRISPR/Cas9 editing efficiency. CRISPR, sgRNA
19  2020 Generation and Characterization of a CRISPR/Cas9 -Induced 3-mst Deficient Zebrafish. 3-MP, 3-MST, CRISPR
20  2020 Generation of an Induced Pluripotent Stem Cell Line with the Constitutive EGFP Reporter. AAVS1, CRISPR, iPSC
21  2020 Genome editing of mutant KRAS through supramolecular polymer-mediated delivery of Cas9 ribonucleoprotein for colorectal cancer therapy. CP, CRC, HA, RNP
22  2020 Genome editing of rodents by electroporation of CRISPR/Cas9 into frozen-warmed pronuclear-stage embryos. CRISPR, TAKE
23  2020 Haploinsufficiency of the Primary Familial Brain Calcification Gene SLC20A2 Mediated by Disruption of a Regulatory Element. CRISPR, HEK293, PFBC, RT-ddPCR
24  2020 Highly efficient 'hit-and-run' genome editing with unconcentrated lentivectors carrying Vpr.Prot.Cas9 protein produced from RRE-containing transcripts. ---
25  2020 Human Papillomavirus Oncogene Manipulation Using Clustered Regularly Interspersed Short Palindromic Repeats/Cas9 Delivered by pH-Sensitive Cationic Liposomes. CRISPR, HPV
26  2020 Improving Horticultural Crops via CRISPR/Cas9: Current Successes and Prospects. CRISPR
27  2020 Invertase inhibitors in potato: towards a biochemical and molecular understanding of cold-induced sweetening. CIS, CRISPR
28  2020 Liver Kinase B1 Fine-Tunes Lineage Commitment of Human Fetal Synovium-Derived Stem Cells. KO, LKB1, OE, qPCR, SDSCs
29  2020 Livestock Gene Editing by One-step Embryo Manipulation. CRISPR
30  2020 Marek's disease virus as a CRISPR/Cas9 delivery system to defend against avian leukosis virus infection in chickens. ALV-J, gRNA, MDV
31  2020 PDK1 regulates auxin transport and Arabidopsis vascular development through AGC1 kinase PAX. CRISPR, PAX
32  2020 Potential Therapeutic Approaches Against Brain Diseases Associated with Cytomegalovirus Infections. CMV, CRISPR, EGSs, HCMV, TALENs
33  2020 Precise editing of myostatin signal peptide by CRISPR/Cas9 increases the muscle mass of Liang Guang Small Spotted pigs. CRISPR, MSTN
34  2020 Proteinase-Activated Receptor 4 Activation Triggers Cell Membrane Blebbing through RhoA and beta-Arrestin. PARs, RhoA
35  2020 Rapid Evaluation of CRISPR Guides and Donors for Engineering Mice. CRISPR, KI, KO
36  2020 Role of RS-1 derivatives in homology-directed repair at the human genome ATG5 locus. CRISPR, HDR, NHEJ
37  2020 Synthetic Biology and Genome-Editing Tools for Improving PHA Metabolic Engineering. CRISPR, PHAs, RBS
38  2020 Targeting human cytomegalovirus IE genes by CRISPR/Cas9 nuclease effectively inhibits viral replication and reactivation. CRISPR, HCMV, IE, sgRNAs
39  2020 The Arabidopsis R-SNARE protein YKT61 is essential for gametophyte development. CRISPR
40  2020 Use Of FlashGel™ DNA Cassettes For Separations In Gene Editing Workflows. CRISPR, sgRNA, ssDNA
41  2019 A Rationally Designed Semiconducting Polymer Brush for NIR-II Imaging-Guided Light-Triggered Remote Control of CRISPR/Cas9 Genome Editing. CRISPR
42  2019 Adenomatous Polyposis Coli as a Major Regulator of Human Embryonic Stem Cells Self-Renewal. APC, CRISPR, FAP, hESCs, PGD, WT
43  2019 Advances in CRISPR/Cas9 Technology for in Vivo Translation. CRISPR
44  2019 An Essential Role for miRNA167 in Maternal Control of Embryonic and Seed Development. ARF6, CRISPR, MIR167
45  2019 Antiviral Agents as Therapeutic Strategies Against Cytomegalovirus Infections. ACT, CMV, CRISPR, EGSs, HCMV, TALENs
46  2019 Application of the CRISPRi system to repress sepF expression in Mycobacterium smegmatis. CRISPRi, sgRNA
47  2019 Applications of the CRISPR/Cas9 System for Rice Grain Quality Improvement: Perspectives and Opportunities. CRISPR, GETs
48  2019 Cas9 Contributes to Group B Streptococcal Colonization and Disease. GBS, TCS
49  2019 Cationic Polymer-Mediated CRISPR/Cas9 Plasmid Delivery for Genome Editing. PC, sgRNA
50  2019 Ceruloplasmin deficiency does not induce macrophagic iron overload: lessons from a new rat model of hereditary aceruloplasminemia. Cp, CRISPR, HA
51  2019 Chromosomal deletions mediated by CRISPR/Cas9 in Helicoverpa armigera. CRISPR, sgRNA
52  2019 Circular RNA profile in liver tissue of EpCAM knockout mice. circRNAs, CRISPRs, EpCAM
53  2019 Construction of an efficient genomic editing system with CRISPR/Cas9 in the vector mosquito Aedes albopictus. CRISPR, kh
54  2019 CRISPR-Based Assessment of Gene Specialization in the Gibberellin Metabolic Pathway in Rice. CRISPR, LOF
55  2019 CRISPR-Cpf1-mediated genome editing and gene regulation in human cells. Cpf1, CRISPR, crRNAs, PAM
56  2019 CRISPR/Cas9 Ribonucleoprotein-mediated Precise Gene Editing by Tube Electroporation. DeepSeq, EGFR, HBB, IL2RG, RNP, SPR, ssODN, TE
57  2019 CRISPR/Cas9-mediated ebony knockout results in puparium melanism in Spodoptera litura. CRISPR
58  2019 CRISPR/Cas9-Mediated Knock-Out of KrasG12D Mutated Pancreatic Cancer Cell Lines. Cas, CRISPR
59  2019 CRISPR/Cas9-targeted mutagenesis of Os8N3 in rice to confer resistance to Xanthomonas oryzae pv. oryzae. CRISPR, T-DNA, Xoo
60  2019 Detection of unamplified target genes via CRISPR-Cas9 immobilized on a graphene field-effect transistor. CRISPR
61  2019 Developing Heritable Mutations in Arabidopsis thaliana Using a Modified CRISPR/Cas9 Toolkit Comprising PAM-Altered Cas9 Variants and gRNAs. CRISPR, gRNA, PAM
62  2019 Development of Improved Fruit, Vegetable, and Ornamental Crops Using the CRISPR/Cas9 Genome Editing Technique. CRISPR
63  2019 Down-regulation of ATF1 leads to early neuroectoderm differentiation of human embryonic stem cells by increasing the expression level of SOX2. ATF1, CRISPR, hESCs, NE, PAX6, shRNA, siRNA, SOX
64  2019 Effective genome editing and identification of a regiospecific gallic acid 4-O-glycosyltransferase in pomegranate (Punica granatum L.). CRISPR, HTs, sgRNAs, UGTs
65  2019 Efficient gene correction of an aberrant splice site in beta-thalassaemia iPSCs by CRISPR/Cas9 and single-strand oligodeoxynucleotides. CRISPR, DSB, HBB, ssODN
66  2019 Favorable Alleles of GRAIN-FILLING RATE1 Increase the Grain-Filling Rate and Yield of Rice. CRISPR, GFR1
67  2019 FBXW7 mutations reduce binding of NOTCH1, leading to cleaved NOTCH1 accumulation and target gene activation in CLL. CLL, CRISPR, FBXW7
68  2019 Fibronectin is up-regulated in podocytes by mechanical stress. CRISPR, Fn1 KD, KO
69  2019 Gene Editing Preserves Visual Functions in a Mouse Model of Retinal Degeneration. CRISPR, HDR, IRDs, rd10
70  2019 Genome Editing in Cowpea Vigna unguiculata Using CRISPR-Cas9. CRISPR, gRNAs, SNF, SYMRK
71  2019 Genome-wide identification of long non-coding RNA targets of the tomato MADS box transcription factor RIN and function analysis. ChIP-seq, CRISPR, lncRNAs, RIN, VIGS
72  2019 Genome-wide target specificity of CRISPR RNA-guided adenine base editors. ---
73  2019 Harnessing CRISPR/Cas 9 System for manipulation of DNA virus genome. CRISPR
74  2019 Immune-orthogonal orthologues of AAV capsids and of Cas9 circumvent the immune response to the administration of gene therapy. AAVs, MHC
75  2019 Injecting Gryllus bimaculatus Eggs. CRISPR, dsRNA, mRNA
76  2019 Insight into Nephrocan Function in Mouse Endoderm Patterning. KO, mESC, Nepn
77  2019 Involvement of BIG1 and BIG2 in regulating VEGF expression and angiogenesis. ARF, BFA, CRISPR, EC, GFP
78  2019 Ku80 gene knockdown by the CRISPR/Cas9 technique affects the biological functions of human thyroid carcinoma cells. CRISPR, TC
79  2019 MicroRNA-375 Suppresses the Growth and Invasion of Fibrolamellar Carcinoma. DNAJB1, FLC, miRNAs, smRNA-seq
80  2019 Multiplex CRISPR Mutagenesis of the Serine/Arginine-Rich (SR) Gene Family in Rice. CRISPR, gRNA, SR
81  2019 Mutation of RGG2, which encodes a type B heterotrimeric G protein gamma subunit, increases grain size and yield production in rice. CRISPR, NIP, ZS97
82  2019 NAPE-PLD controls OEA synthesis and fat absorption by regulating lipoprotein synthesis in an in vitro model of intestinal epithelial cells. CRISPR, FAE, NAPE, NAPE-PLD, OEA
83  2019 Overcoming Self-Incompatibility in Diploid Potato Using CRISPR-Cas9. KOs, sgRNA
84  2019 Pooled CRISPR/Cas9 reveals redundant roles of plastidial phosphoglycerate kinases in carbon fixation and metabolism. CRISPR, PGK
85  2019 Programmable activation of Bombyx gene expression using CRISPR/dCas9 fusion systems. Cpf1, CRISPR, CRISPRa, SpCas9
86  2019 Rapid and efficient production of genome-edited animals by electroporation into oocytes injected with frozen or freeze-dried sperm. CRISPR, ICSI
87  2019 Rapid Screening of CRISPR/Cas9-Induced Mutants Using the ACT-PCR Method. ACT-PCR, CRISPR, PCR
88  2019 Regulation of steroidogenic function of luteal cells by thrombospondin and insulin in water buffalo (Bubalus bubalis). CD36, CRISPR, TSP-1, vWF
89  2019 Restoration of FVIII expression by targeted gene insertion in the FVIII locus in hemophilia A patient-derived iPSCs. CRISPR, EF-1alpha, FVIII, HDR, iPSCs, TALEN, ZFN
90  2019 Scleraxis genes are required for normal musculoskeletal development and for rib growth and mineralization in zebrafish. CRISPR, scx
91  2019 Sequential disruption of ALV host receptor genes reveals no sharing of receptors between ALV subgroups A, B, and J. ALV, chNHE1, CRISPR, wtTVA
92  2019 Single crossover-mediated targeted nucleotide substitution and knock-in strategies with CRISPR/Cas9 system in the rice blast fungus. CRISPR, HR
93  2019 Syntaxin-17-Dependent Mitochondrial Dynamics is Essential for Protection Against Oxidative-Stress-Induced Apoptosis. CRISPR, ER, ERGIC, KO, mRFP, ROS, STX17, TBH
94  2019 Targeted gene insertion into Z chromosome of chicken primordial germ cells for avian sexing model development. CRISPR, PGCs
95  2019 The ABCs of CRISPR in Tephritidae: developing methods for inducing heritable mutations in the genera Anastrepha, Bactrocera and Ceratitis. ---
96  2019 The implication of CRISPR/Cas9 genome editing technology in combating human oncoviruses. CRISPR
97  2019 The length of guide RNA and target DNA heteroduplex effects on CRISPR/Cas9 mediated genome editing efficiency in porcine cells. CRISPR, nt
98  2019 The Masc gene product controls masculinization in the black cutworm, Agrotis ipsilon. CRISPR, Masc
99  2019 The N-Terminal Domain of Spike Protein Is Not the Enteric Tropism Determinant for Transmissible Gastroenteritis Virus in Piglets. CRISPR, TGEV
100  2019 The potential application of genome editing by using CRISPR/Cas9, and its engineered and ortholog variants for studying the transcription factors involved in the maintenance of phosphate homeostasis in model plants. CRISPR, GM, TFs