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Abbreviation : Cx43
Long Form : connexin 43
No. Year Title Co-occurring Abbreviation
2020 A role for connexin-43 in Duchenne muscular dystrophy cardiomyopathy. DMD
2020 Acellular Human Amniotic Membrane Scaffold with 15d-PGJ2 Nanoparticles in Postinfarct Rat Model. LVEDV, LVEF, LVESV
2020 Activation of Astroglial Connexin is Involved in Concentration-Dependent Double-Edged Sword Clinical Action of Clozapine. CLZ, VPA
2020 Adenoviral transduction of EGFR into pregnancy-adapted uterine artery endothelial cells remaps growth factor induction of endothelial dysfunction. GJC, PE
2020 Alcohol consumption combined with dietary low-carbohydrate/high-protein intake increased the left ventricular systolic dysfunction risk and lethal ventricular arrhythmia susceptibility in apolipoprotein E/low-density lipoprotein receptor double-knockout mice. ADRB, AL, LCHP, LV
2020 alpha1AMP-Activated Protein Kinase Protects against Lipopolysaccharide-Induced Endothelial Barrier Disruption via Junctional Reinforcement and Activation of the p38 MAPK/HSP27 Pathway. AMPK, HSP27, LPS, VE-cad, ZO-1
2020 Amphiphilic aminoglycosides with increased selectivity for inhibition of connexin 43 (Cx43) hemichannels. ---
2020 Amyloid-beta regulates gap junction protein Connexin 43 trafficking in cultured primary astrocytes. AD
2020 An Alternatively Translated Connexin 43 Isoform, GJA1-11k, Localizes to the Nucleus and Can Inhibit Cell Cycle Progression. GJ
10  2020 Androgen Indirectly Regulates Gap Junction Component Connexin 43 Through Wilms Tumor-1 in Sertoli Cells. WT1
11  2020 Angiotensin II induces RAW264.7 macrophage polarization to the M1‑type through the connexin 43/NF‑kappaB pathway. Ang II, iNOS, TNF
12  2020 Anti-Arrhythmic Effects of Linalool via Cx43 Expression in a Rat Model of Myocardial Infarction. LAD
13  2020 Antiarrhythmic Effects of Melatonin and Omega-3 Are Linked with Protection of Myocardial Cx43 Topology and Suppression of Fibrosis in Catecholamine Stressed Normotensive and Hypertensive Rats. ISO, VF
14  2020 Apelin-13 regulates angiotensin II-induced Cx43 downregulation and autophagy via the AMPK/mTOR signaling pathway in HL-1 cells. AMPK, BNP
15  2020 Apocynin Treatment Prevents Cardiac Connexin 43 Hemichannels Hyperactivity by Reducing Nitroso-Redox Stress in Mdx Mice. DMD
16  2020 Association of vascular endothelial growth factor A polymorphisms and aberrant expression of connexin 43 and VEGFA with idiopathic recurrent spontaneous miscarriage. IRSM, VEGF-A
17  2020 Astroglial Connexin 43 Deficiency Protects against LPS-Induced Neuroinflammation: A TSPO Brain PET Study with [18F]FEPPA. LPS, PET
18  2020 Automatic Quantification of Cardiomyocyte Dimensions and Connexin 43 Lateralization in Fluorescence Images. ---
19  2020 Auxiliary trafficking subunit GJA1-20k protects connexin-43 from degradation and limits ventricular arrhythmias. ---
20  2020 beta2-Adrenergic Receptor Stimulation Upregulates Cx43 Expression on Glioblastoma Multiforme and Olfactory Ensheathing Cells. beta2AR, GBM, GJIC, OECs
21  2020 Blocking Connexin-43 mediated hemichannel activity protects against early tubular injury in experimental chronic kidney disease. ATP, CKD, EMT, GJIC, HC, hPTECs, NLR, PTECs, TGF-beta1, UUO, ZO-1
22  2020 Bone marrow regeneration requires mitochondrial transfer from donor Cx43-expressing hematopoietic progenitors to stroma. BM, BMT, HSPC, ME, MSC
23  2020 Caduet enhances connexin 43 phosphorylation in left ventricular and thoracic aorta of SH model rats. BP, HR, LVMI, SH, SHR, SHR-AM, WKY
24  2020 Canonical and Non-Canonical Roles of Connexin43 in Cardioprotection. I/R
25  2020 Cardiac beta-adrenergic receptor activation mediates distinct and cell type-dependent changes in the expression and distribution of connexin 43. beta-ARs
26  2020 Cisplatin-Induced Stria Vascularis Damage Is Associated with Inflammation and Fibrosis. ABR, BCs, Cx26, ECs, EP, HC, IL-1beta, MCs, SV, TEM, ZO-1
27  2020 Collective invasion induced by an autocrine purinergic loop through connexin-43 hemichannels. ---
28  2020 Connexin 43 gap junctional intercellular communication inhibits evx1 expression and joint formation in regenerating fins. GJIC
29  2020 Connexin 43 Knockdown Induces Mitochondrial Dysfunction and Affects Early Developmental Competence in Porcine Embryos. ROS
30  2020 Connexin 43 Modulates the Cellular Resistance to Paclitaxel via Targeting beta-Tubulin in Triple-Negative Breast Cancer. Co-IP, PLA
31  2020 Connexin 43 plays a role in proliferation and migration of pulmonary arterial fibroblasts in response to hypoxia. MAPK, PAFs, PH, rPAFs, rPASMCs
32  2020 Connexin 43 upregulation in burns promotes burn conversion through spread of apoptotic death signals. HSP47
33  2020 Connexin 43: A novel ginsenoside Rg1-sensitive target in a rat model of depression. ---
34  2020 Connexin-43 reduction prevents muscle defects in a mouse model of manifesting Duchenne muscular dystrophy female carriers. DMD, ESCs, WT
35  2020 Connexin43 peptide, TAT-Cx43266-283, selectively targets glioma cells, impairs malignant growth, and enhances survival in mouse models in vivo. ---
36  2020 Cx43 and AKAP95 regulate G1/S conversion by competitively binding to cyclin E1/E2 in lung cancer cells. AKAP95
37  2020 Cx43 and Associated Cell Signaling Pathways Regulate Tunneling Nanotubes in Breast Cancer Cells. FAK, KO, PKA, TNTs, WT
38  2020 Cx43 in Neural Progenitors Promotes Glioma Invasion in a 3D Culture System. ---
39  2020 Cx43 promotes SHF-DPCs proliferation in the hair follicle of Albas cashmere goats from anagen to telogen. SHF, SHF-DPCs
40  2020 Danegaptide Enhances Astrocyte Gap Junctional Coupling and Reduces Ischemic Reperfusion Brain Injury in Mice. GJ, MALDI IMS
41  2020 Design and characterization of an electroconductive scaffold for cardiomyocytes based biomedical assays. CG, cTnT, CVD, ECM, GAGs, NMCM, pCG, PPy, Py
42  2020 Dexmedetomidine Attenuates LPS-Induced Monocyte-Endothelial Adherence via Inhibiting Cx43/PKC-alpha/NOX2/ROS Signaling Pathway in Monocytes. HUVECs
43  2020 Dexmedetomidine Attenuates Monocyte-Endothelial Adherence via Inhibiting Connexin43 on Vascular Endothelial Cells. HUVECs, sICAM-1, sVCAM-1
44  2020 Dexmedetomidine Exerted Anti-arrhythmic Effects in Rat With Ischemic Cardiomyopathy via Upregulation of Connexin 43 and Reduction of Fibrosis and Inflammation. AMPK, BML, DEX, ICM
45  2020 Differential expression of cell-cell junction proteins in the testis, epididymis, and ductus deferens of domestic turkeys (Meleagris gallopavo) with white and yellow semen. WNS, YSS, ZO-1
46  2020 Downregulation of gap junctional intercellular communication and connexin 43 expression by bisphenol A in human granulosa cells. BPA, GCs, GJIC
47  2020 Effect of ischemic postconditioning on cell apoptosis and expression of relevant genes in non-culprit coronary arteries. AT1, qRT-PCR, TUNEL
48  2020 Effect of seasonal variance on intestinal epithelial barriers and the associated innate immune response of the small intestine of the Chinese soft-shelled turtles. ACs, GCs, MGs, TLR2 and 4, ZO-1
49  2020 Effects of Carbamazepine, Lacosamide and Zonisamide on Gliotransmitter Release Associated with Activated Astroglial Hemichannels. ATP, CBX, CBZ, LCM, OFC, ZNS
50  2020 Effects of Electroacupuncture on Ovarian Expression of the Androgen Receptor and Connexin 43 in Rats with Letrozole-Induced Polycystic Ovaries. AMH, AR, EA, ELISA, FAI, FBG, FINS, FSH, INHB, INS, LE, LH, PCOS, SHBG
51  2020 Effects of Reduced Connexin43 Function on Mandibular Morphology and Osteogenesis in Mutant Mouse Models of Oculodentodigital Dysplasia. ODDD
52  2020 Effects of reduced connexin43 function on skull development in the Cx43I130T/+ mutant mouse that models oculodentodigital dysplasia. ODDD
53  2020 Endocrine-disrupting chemicals rapidly affect intercellular signaling in Leydig cells. EDCs, GJIC
54  2020 Epithelial tissue geometry directs emergence of bioelectric field and pattern of proliferation. Vm
55  2020 Establishment and functional characterization of a murine primary Sertoli cell line deficient of connexin43. BTB, IF, KO, SC, WB, WT
56  2020 Examination of sulfonamide-based inhibitors of MMP3 using the conditioned media of invasive glioma cells. GBM
57  2020 Expression and functional regulation of gap junction protein connexin 43 in dermal mesenchymal stem cells from psoriasis patients. DMSCs, GJIC, MSCs
58  2020 Gap junction connexin43 is a key element in mediating phagocytosis activity in human trabecular meshwork cells. TM
59  2020 Gap junctions amplify TRPV4 activation-initiated cell injury via modification of intracellular Ca2+ and Ca2+-dependent regulation of TXNIP. GJ
60  2020 Gap-134, a Connexin43 activator, prevents age-related development of ventricular fibrosis in Scn5a+/- mice. ---
61  2020 Granulocyte colony-stimulating factor attenuates myocardial remodeling and ventricular arrhythmia susceptibility via the JAK2-STAT3 pathway in a rabbit model of coronary microembolization. CME, G-CSF, G-CSFR, LAD, VERP
62  2020 High Glucose Downregulates Connexin 43 Expression and Its Gap Junction and Hemichannel Function in Osteocyte-like MLO-Y4 Cells Through Activation of the p38MAPK/ERK Signal Pathway. mCx43
63  2020 High-mobility group box-1 induces mechanical pain hypersensitivity through astrocytic connexin 43 via the toll-like receptor-4/JNK signaling pathway. EtBr, HMGB-1, TLR4
64  2020 HIV gp120 Protein Increases the Function of Connexin 43 Hemichannels and Pannexin-1 Channels in Astrocytes: Repercussions on Astroglial Function. HAND, HIV
65  2020 Human Endometrial Stromal Cell Differentiation is Stimulated by PPARbeta/delta Activation: New Targets for Infertility? ERalpha, ESCs, IL, VEGF
66  2020 Human Induced Pluripotent Stem Cell-Derived Non-Cardiomyocytes Modulate Cardiac Electrophysiological Maturation Through Connexin 43-Mediated Cell-Cell Interactions. AP, hiPSC-CMs, non-CMs, shRNA
67  2020 Human-iPSC-Derived Cardiac Stromal Cells Enhance Maturation in 3D Cardiac Microtissues and Reveal Non-cardiomyocyte Contributions to Heart Disease. cAMP, CFs, CMs, hiPSCs, MTs
68  2020 Hyperactive reactive oxygen species impair function of porcine Sertoli cells via suppression of surface protein ITGB1 and connexin-43. ROS, SSCs
69  2020 Hyperbaric oxygen therapy relieved pruritus and pain of keloid patients. HBO, RT-qPCR, TPH1, TRPV1
70  2020 Impact of perinatal bisphenol A and 17beta estradiol exposure: Comparing hormone receptor response. BPA, ERalpha, MG, PgR, VC
71  2020 Inhibition of connexin 43 attenuates oxidative stress and apoptosis in human umbilical vein endothelial cells. ATOX1, CYBB, GSS, GSTZ1, HMOX1, HUVECs, LPS, mtCx43, qPCR, ROS
72  2020 Inhibition of Gap Junction-Mediated Intercellular Communication by Poly(I:C) in Cultured Human Corneal Fibroblasts. GJIC, HCFs, JNK, MAPK, NAC, SOD
73  2020 Inhibition of MicroRNA-206 Ameliorates Ischemia-Reperfusion Arrhythmia in a Mouse Model by Targeting Connexin43. cTnI, HR, IR, MAP, miR-206, RA, RPP
74  2020 Inhibition of P2X7R in the amygdala ameliorates symptoms of neuropathic pain after spared nerve injury in rats. FST, GAP43, GFAP, IBA1, MWT, NP, OFT, P2X7R, SNI, SPT, TST, TWD
75  2020 Interleukin-8 drives CD38 to form NAADP from NADP+ and NAAD in the endolysosomes to mobilize Ca2+ and effect cell migration. IL-8, LAK, NA, NAAD, NAADP, NAPRT, NMNAT
76  2020 Isoflurane Postconditioning Upregulates Phosphorylated Connexin 43 in the Middle Cerebral Artery Occlusion Model and Is Probably Associated with the TGF-beta1/Smad2/3 Signaling Pathway. I/R, ISPOC, MCAO, p-Cx43
77  2020 Levo-corydalmine Attenuates Vincristine-Induced Neuropathic Pain in Mice by Upregulating the Nrf2/HO-1/CO Pathway to Inhibit Connexin 43 Expression. CO, HO-1, Nrf2
78  2020 Liraglutide Effect on Ventricular Transient Outward K +  Channel and Connexin-43 Protein Expression. QUICKI index
79  2020 Loss of Cx43 in Murine Sertoli Cells Leads to Altered Prepubertal Sertoli Cell Maturation and Impairment of the Mitosis-Meiosis Switch. GCs, NGS, SC
80  2020 Lycopene Protects against Smoking-Induced Lung Cancer by Inducing Base Excision Repair. ATRA, BC
81  2020 Mechanisms underlying astrocytic connexin-43 autophagy degradation during cerebral ischemia injury and the effect on neuroinflammation and cell apoptosis. ---
82  2020 Metformin ameliorates cardiac conduction delay by regulating microRNA-1 in mice. APD, CV, MET, MI, miR-1, Tg
83  2020 Metoprolol protects against myocardial infarction by inhibiting miR-1 expression in rats. LAD, MI
84  2020 MicroRNA-1298-5p inhibits cell proliferation and the invasiveness of bladder cancer cells via down-regulation of connexin 43. BC, miR
85  2020 miR-130b regulates gap junctional intercellular communication through connexin 43 in granulosa cells from patients with polycystic ovary syndrome. GJIC, miRNAs, PCOS
86  2020 Morphokinetic analysis of cleavage stage embryos and assessment of specific gene expression in cumulus cells independently predict human embryo development to expanded blastocyst: a preliminary study. BMP15, CCs, COXII, HO-1
87  2020 Muscular atrophy, impaired epithelial autophagy and UCHL1 increase in androgen-deficient cauda epididymis. AR, UPS
88  2020 Neutrophil Swarming in Damaged Tissue Is Orchestrated by Connexins and Cooperative Calcium Alarm Signals. LTB4
89  2020 Pirfenidone attenuates homocysteine‑induced apoptosis by regulating the connexin 43 pathway in H9C2 cells. Hcy, PFD
90  2020 Prevention of connexin-43 remodeling protects against Duchenne muscular dystrophy cardiomyopathy. DMD, NOX2
91  2020 Propofol protects against oxygen/glucose deprivation‑induced cell injury via gap junction inhibition in astrocytes. OGD, OGD/R
92  2020 Pulpal upregulation of connexin 43 during pulpitis. ---
93  2020 Redistribution of metabolic resources through astrocyte networks mitigates neurodegenerative stress. ---
94  2020 Regular Exercise Participation Contributes to Better Proteostasis, Inflammatory Profile, and Vasoactive Profile in Patients With Hypertension. eNOS, FTIR, HSP70, IL, MMP-2, SF-36, SOD3, TIMP-2
95  2020 Regulation of calcium dynamics and propagation velocity by tissue microstructure in engineered strands of cardiac tissue. ---
96  2020 Relationship Between Hematoma Expansion Induced by Hypertension and Hyperglycemia and Blood-brain Barrier Disruption in Mice and Its Possible Mechanism: Role of Aquaporin-4 and Connexin43. AQP4, BBB, HE, HH-HE
97  2020 RhoA/ROCK Regulates Prion Pathogenesis by Controlling Connexin 43 Activity. ROCK
98  2020 Salidroside Attenuates Hypoxia-Induced Expression of Connexin 43 in Corpus Cavernosum Smooth Muscle Cells. HIF-1alpha
99  2020 Senolytic activity of small molecular polyphenols from olive restores chondrocyte redifferentiation and promotes a pro-regenerative environment in osteoarthritis. OA, OACs
100  2020 Simplified method to quantify valve back-leak uncovers severe mesenteric lymphatic valve dysfunction in mice deficient in connexins 43 and 37. ---