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Abbreviation : Cxs
Long Form : connexins
No. Year Title Co-occurring Abbreviation
2021 Mast Cell and Astrocyte Hemichannels and Their Role in Alzheimer's Disease, ALS, and Harmful Stress Conditions. AD, ALS, APOE, ATP, HCs, MCs
2020 A Conserved LIR Motif in Connexins Mediates Ubiquitin-Independent Binding to LC3/GABARAP Proteins. GJ
2020 Altered Expression of Glial Gap Junction Proteins Cx43, Cx30, and Cx47 in the 5XFAD Model of Alzheimer's Disease. AD, CNS, MS, OPCs
2020 Connexin Signaling in the Juxtaglomerular Apparatus (JGA) of Developing, Postnatal Healthy and Nephrotic Human Kidneys. EM, JC, JGA, RAS
2020 Efficacy of THN201, a Combination of Donepezil and Mefloquine, to Reverse Neurocognitive Deficits in Alzheimer's Disease. DPZ, MEF
2020 Expression of Connexins 37, 43 and 45 in Developing Human Spinal Cord and Ganglia. DRG, SC
2020 Genetic and pharmacological inactivation of astroglial connexin 43 differentially influences the acute response of antidepressant and anxiolytic drugs. CBX, KD
2020 Role of Connexins 30, 36, and 43 in Brain Tumors, Neurodegenerative Diseases, and Neuroprotection. CNS, GJ
2020 The role of connexins and pannexins in orofacial pain. ---
10  2019 beta‑estradiol alleviates hypertension‑ and concanavalin A‑mediated inflammatory responses via modulation of connexins in peripheral blood lymphocytes. CD, Con A, GJs, SHR, WKY
11  2019 Carbenoxolone decreases monocrotaline‑induced pulmonary inflammation and pulmonary arteriolar remodeling in rats by decreasing the expression of connexins in T lymphocytes. CBX, i.p, MCT, RVHI
12  2019 Connexin43 Is Required for the Effective Activation of Spleen Cells and Immunoglobulin Production. Cx43, Gjs, LPS, NOX2
13  2019 Gap Junction Intercellular Communication in the Carcinogenesis Hallmarks: Is This a Phenomenon or Epiphenomenon? GJIC, GJs
14  2019 High-Content Screening Identifies New Inhibitors of Connexin 43 Gap Junctions. Cx43, GJs
15  2019 Hypoxia‑induced internalization of connexin 26 and connexin43 in pulmonary epithelial cells is involved in the occurrence of non‑small cell lung cancer via the P53/MDM2 signaling pathway. EMT, MDM2, NSCLC
16  2019 Neuronal Activity Drives Astroglial Connexin 30 in Perisynaptic Processes and Shapes Its Functions. GJ
17  2019 Neuroprotective effects of Rosmarinus officinalis L. extract in oxygen glucose deprivation (OGD)-injured human neural-like cells. GJ, OGD, SDROE
18  2019 Role of Connexins in Chronic Pain and Their Potential as Therapeutic Targets for Next-Generation Analgesics. ---
19  2019 Transient receptor potential vanilloid 4 is involved in the upregulation of connexin expression following pilocarpine-induced status epilepticus in mice. PISE, TRPV4
20  2018 Conditioned Media From Glial Cells Promote a Neural-Like Connexin Expression in Human Adipose-Derived Mesenchymal Stem Cells. ASCs, CM, OECs, SCs
21  2018 Connexin 30 Deficiency Attenuates Chronic but Not Acute Phases of Experimental Autoimmune Encephalomyelitis Through Induction of Neuroprotective Microglia. CNS, EAE, KO, MS
22  2018 Dileucine-like motifs in the C-terminal tail of connexin32 control its endocytosis and assembly into gap junctions. ---
23  2018 Hydrogen Sulfide Attenuates Hypertensive Inflammation via Regulating Connexin Expression in Spontaneously Hypertensive Rats. SHR, WKYs
24  2018 The Complex Subtype-Dependent Role of Connexin 43 (GJA1) in Breast Cancer. Cx43
25  2017 Bioelectrical signals improve cardiac function and modify gene expression of extracellular matrix components. IL, LVEF, MMP, SHRs, TGF, TIMP3
26  2017 Connexins, important players in the dissemination of prostate cancer cells. GJIC, PCa
27  2017 Correlation between connexin and traumatic brain injury in patients. MAPK, PKC, TBI
28  2017 Inhibition of Cx43 mediates protective effects on hypoxic/reoxygenated human neuroblastoma cells. Cx43, GJs, HCs, OEC-CM, OECs
29  2017 On Biophysical Properties and Sensitivity to Gap Junction Blockers of Connexin 39 Hemichannels Expressed in HeLa Cells. DCFS, GJCs, HCs, HeLa-Cx39 cells, RMPs
30  2017 Permeant-specific gating of connexin 30 hemichannels. MTS-ET, SCAM
31  2017 Regulation of Connexin-Based Channels by Fatty Acids. FAs, GJCs, HCs
32  2017 TNF‑alpha regulates apoptosis of human vascular smooth muscle cells through gap junctions. VSMCs
33  2016 Carbon Monoxide Modulates Connexin Function through a Lipid Peroxidation-Dependent Process: A Hypothesis. CO
34  2016 Communication Through Gap Junctions in the Endothelium. ---
35  2016 Connexin 43 Acts as a Proapoptotic Modulator in Cisplatin-Induced Auditory Cell Death. 18alpha-GA, BFA, CT, siRNA
36  2016 Connexins, E-cadherin, Claudin-7 and beta-catenin transiently form junctional nexuses during the post-natal mammary gland development. ---
37  2016 Dexamethasone and levetiracetam reduce hetero-cellular gap-junctional coupling between F98 glioma cells and glial cells in vitro. DEX, GJs, H-GJC, LEV
38  2016 GAP junctional communication in brain secondary organizers. GJs
39  2016 The Role of Pannexin 3 in Bone Biology. ER, KO, MMP, OA, VEGF
40  2015 Carbon monoxide: A new player in the redox regulation of connexin hemichannels. CO
41  2015 Cx43 and mechanotransduction in bone. Cx43
42  2015 Diseases associated with leaky hemichannels. GJCs, HCs
43  2015 Early disruption of glial communication via connexin gap junction in multiple sclerosis, Balo's disease and neuromyelitis optica. anti-AQP4, BD, GJs, MS, NMO
44  2015 Helicobacter pylori VacA induces apoptosis by accumulation of connexin 43 in autophagic vesicles via a Rac1/ERK-dependent pathway. GJs, H. pylori, VacA
45  2015 Involvement of calpain in 4-hydroxynonenal-induced disruption of gap junction-mediated intercellular communication among fibrocytes in primary cultures derived from the cochlear spiral ligament. 4-HNE, GJ-IC
46  2015 Left-sided Noninvasive Vagus Nerve Stimulation Suppresses Atrial Fibrillation by Upregulating Atrial Gap Junctions in Canines. AF, LL-TS, RAP
47  2015 MMP-9- and NMDA receptor-mediated mechanism of diabetic renovascular remodeling and kidney dysfunction: hydrogen sulfide is a key modulator. DKO, ECM, MMP-9, RI
48  2015 Mouse Hepatitis Virus Infection Remodels Connexin43-Mediated Gap Junction Intercellular Communication In Vitro and In Vivo. CNS, EAE, ER/ERGIC, GJIC, GJs, MHV, MS
49  2015 Post-transcriptional regulation of connexins. HuR, IRES, RBPs
50  2015 Study on connexin gene and protein expression and cellular distribution in relation to real-time proliferation of porcine granulosa cells. GCs, GJCs, RTCA
51  2015 Targeting connexin 43 with alpha-connexin carboxyl-terminal (ACT1) peptide enhances the activity of the targeted inhibitors, tamoxifen and lapatinib, in breast cancer: clinical implication for ACT1. ---
52  2015 The impact of caffeine on connexin expression in the embryonic chick cardiomyocyte micromass culture system. ---
53  2014 A new angle on blood-CNS interfaces: a role for connexins? BBB, BCSFB, CPE, ECs, GJ
54  2014 AMSH-mediated deubiquitination of Cx43 regulates internalization and degradation of gap junctions. DUBs, GJs
55  2014 Connexins-mediated glia networking impacts myelination and remyelination in the central nervous system. ASTs, CNS, OLs
56  2014 Extracellular gentamicin reduces the activity of connexin hemichannels and interferes with purinergic Ca(2+) signaling in HeLa cells. GJCs, HCs
57  2014 Neuronal involvement in muscular atrophy. ACh, BDNF, HCs, Lrp4, MuSK, P2X7Rs, TRPV2
58  2014 Possible role of hemichannels in cancer. ---
59  2014 Regulation of hemichannels and gap junction channels by cytokines in antigen-presenting cells. APCs, GJCs, HCs
60  2014 Spatiotemporal changes in Cx30 and Cx43 expression during neuronal differentiation of P19 EC and NT2/D1 cells. ---
61  2014 The connexin 30.3 of zebrafish homologue of human connexin 26 may play similar role in the inner ear. IHC, RT-PCR, WISH
62  2014 The connexin43 mimetic peptide Gap19 inhibits hemichannels without altering gap junctional communication in astrocytes. ---
63  2014 [Molecular pathology of multiple sclerosis and neuromyelitis optica]. AQP4, CNS, GFAP, MS, NMO
64  2013 17-beta-Estradiol counteracts the effects of high frequency electromagnetic fields on trophoblastic connexins and integrins. ER, HFEMFs, Ints
65  2013 A mechanism of gap junction docking revealed by functional rescue of a human-disease-linked connexin mutant. ---
66  2013 Connexin a check-point component of cell apoptosis in normal and physiopathological conditions. ---
67  2013 Connexin and pannexin hemichannels in brain glial cells: properties, pharmacology, and roles. ---
68  2013 Connexin expression patterns in arrhythmogenic right ventricular cardiomyopathy. ARVC
69  2013 Connexin32 inhibits gastric carcinogenesis through cell cycle arrest and altered expression of p21Cip1 and p27Kip1. Cip1, Cip1
70  2013 Contribution of intracellular calcium and pH in ischemic uncoupling of cardiac gap junction channels formed of connexins 43, 40, and 45: a critical function of C-terminal domain. CT, GJ, OGD
71  2013 Human articular chondrocytes express multiple gap junction proteins: differential expression of connexins in normal and osteoarthritic cartilage. OA
72  2013 Involvement of connexins 43 and 45 in functional mechanism of human detrusor overactivity in neurogenic bladder. NDO
73  2013 Overexpression of CXCL12 chemokine up-regulates connexin and integrin expression in mesenchymal stem cells through PI3K/Akt pathway. ECM
74  2013 Phosphorylation on Ser-279 and Ser-282 of connexin43 regulates endocytosis and gap junction assembly in pancreatic cancer cells. ---
75  2013 Role of gap junctions and hemichannels in parasitic infections. ---
76  2012 Action of db-cAMP on the bystander effect and chemosensitivity through connexin 43 and Bcl-2-mediated pathways in medulloblastoma cells. BE, dbcAMP, GCV, GJIC, MB
77  2012 Connexin 36 is expressed in beta and connexins 26 and 32 in acinar cells at the end of the secondary transition of mouse pancreatic development and increase during fetal and perinatal life. dpc, dpp
78  2012 Curious and contradictory roles of glial connexins and pannexins in epilepsy. GJC
79  2012 Epidermal growth factor regulates connexin 43 in the human epididymis: role of gap junctions in azoospermia. EGF, EGFR, GJs, PI3K
80  2012 Exogenous CXCL12 activates protein kinase C to phosphorylate connexin 43 for gap junctional intercellular communication among confluent breast cancer cells. BC, BCCs, GJIC
81  2012 Expression of connexin 26 and bovine papillomavirus E5 in cutaneous fibropapillomas of cattle. BPVs
82  2012 Expression of connexin 30 and connexin 32 in hippocampus of rat during epileptogenesis in a kindling model of epilepsy. GJs
83  2012 Glomerular expression of connexin 40 and connexin 43 in rat experimental glomerulonephritis. GN, SMA
84  2011 Atrial tachycardia/fibrillation in the connexin 43 G60S mutant (Oculodentodigital dysplasia) mouse. AF, AT/F, CCh, WT
85  2011 Connexin implication in the control of the murine beta-cell mass. ---
86  2011 Connexin37 and Connexin43 deficiencies in mice disrupt lymphatic valve development and result in lymphatic disorders including lymphedema and chylothorax. ---
87  2011 Connexin43 signaling contributes to spontaneous apoptosis in cultures of primary hepatocytes. ---
88  2011 Connexins and the gap in context. GJ
89  2011 Connexins as therapeutic targets in lung disease. GJIC
90  2011 Glial connexin expression and function in the context of Alzheimer's disease. ---
91  2011 Increased myoendothelial gap junctions mediate the enhanced response to epoxyeicosatrienoic acid and acetylcholine in mesenteric arterial vessels of cirrhotic rats. 18alpha-GA, ACh, EET, GJ
92  2011 Iroquois homeobox gene 3 establishes fast conduction in the cardiac His-Purkinje network. Irx3
93  2011 Mutation screening of the GJA7 (Cx45) gene in a large international series of probands with nonsyndromic hearing impairment. ---
94  2010 Altered expression and localization of connexin32 in human and murine gastric carcinogenesis. ---
95  2010 Assembly of connexin43 into gap junctions is regulated differentially by E-cadherin and N-cadherin in rat liver epithelial cells. E-cad, GJs, NCAD
96  2010 Astroglial connexin immunoreactivity is specifically altered at beta-amyloid plaques in beta-amyloid precursor protein/presenilin1 mice. AD, APP, PS1
97  2010 Changes in hippocampal connexin 36 mRNA and protein levels during epileptogenesis in the kindling model of epilepsy. ---
98  2010 Clinical significance of the expression of connexin26 in colorectal cancer. Cx26, TUNEL
99  2010 Compartmentalized connexin 43 s-nitrosylation/denitrosylation regulates heterocellular communication in the vessel wall. ---
100  2010 Connexin channel-dependent signaling pathways in inflammation. ---