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Abbreviation : D1R
Long Form : D1 receptor
No. Year Title Co-occurring Abbreviation
2020 A Neurofunctional Domains Approach to Evaluate D1/D5 Dopamine Receptor Partial Agonism on Cognition and Motivation in Healthy Volunteers With Low Working Memory Capacity. AEs
2020 Atopic dermatitis induces anxiety- and depressive-like behaviors with concomitant neuronal adaptations in brain reward circuits in mice. AD, BDNF, CREB, DARPP32, DS, NAc, TH, VTA
2020 Binding of Dopamine D1 Receptor and Noradrenaline Transporter in Individuals with Autism Spectrum Disorder: A PET Study. ASD, DA, NA, NAT
2020 Blockade of the dopaminergic neurotransmission with AMPT and reserpine induces a differential expression of genes of the dopaminergic phenotype in substantia nigra. SN
2020 Cardiac dopamine D1 receptor triggers ventricular arrhythmia in chronic heart failure. CMs
2020 Chemogenetic Inhibition of Dopamine D1-expressing Neurons in the Dorsal Striatum does not alter Methamphetamine Intake in either Male or Female Long Evans Rats. CNO, METH, SA
2020 Cortical Foxp2 Supports Behavioral Flexibility and Developmental Dopamine D1 Receptor Expression. NDDs
2020 Cross-talk between dopamine D1 and corticotropin releasing factor type 2 receptors leads to occlusion of their ERK1/2 signaling. CRF2alpha
2020 D1 receptors in the anterior cingulate cortex modulate basal mechanical sensitivity threshold and glutamatergic synaptic transmission. ACC, AMPAR, DA
10  2020 Dopamine D1 receptor availability is not associated with delusional ideation measures of psychosis proneness. ---
11  2020 Dopamine D1 receptor in the NAc shell is involved in delayed emergence from isoflurane anesthesia in aged mice. EEG, MSNs, NAc
12  2020 Dopamine D1 receptor signalling in dyskinetic Parkinsonian rats revealed by fiber photometry using FRET-based biosensors. FRET, GPCRs, LID, PD, PKA
13  2020 Dopamine D1 Receptors Regulate Spines in Striatal Direct-Pathway and Indirect-Pathway Neurons. EGFP
14  2020 Dopamine D1R-neuron cacna1c deficiency: a new model of extinction therapy-resistant post-traumatic stress. PTSD
15  2020 Dopamine receptor cooperativity synergistically drives dyskinesia, motor behavior, and striatal GABA neurotransmission in hemiparkinsonian rats. AIMs, D2R, DA, FAS, GABA, LID, PD
16  2020 Dopamine-Dependent QR2 Pathway Activation in CA1 Interneurons Enhances Novel Memory Formation. miR-182, QR2
17  2020 Early diabetes impairs ON sustained ganglion cell light responses and adaptation without cell death or dopamine insensitivity. EPSCs, IPSCs
18  2020 Environmental enrichment reduces behavioural sensitization in mice previously exposed to toluene: The role of D1 receptors. EE
19  2020 Genetic variants in dopamine receptors influence on heterodimerization in the context of antipsychotic drug action. D2R
20  2020 In vivo imaging of dopamine D1 receptor and activated microglia in attention-deficit/hyperactivity disorder: a positron emission tomography study. ACC, ADHD, DLPFC, OFC, PET, TD
21  2020 In vivo reduction of striatal D1R by RNA interference alters expression of D1R signaling-related proteins and enhances methamphetamine addiction in male rats. Cav-1, DAT, DS, shRNA
22  2020 Injection of D1 receptor antagonist SCH23390 into the periaqueductal gray attenuates morphine withdrawal symptoms in rats. CaMKII, CREB, p-ERK, PAG
23  2020 Modulation of dopamine D1 receptors via histamine H3 receptors is a novel therapeutic target for Huntington's disease. H3R, HD
24  2020 On the G Protein-Coupled Receptor Neuromodulation of the Claustrum. DA, DEn, IR, KOR, PLA, SSTR2, TH
25  2020 Phosphorylation barcode-dependent signal bias of the dopamine D1 receptor. GPCRs
26  2020 Prenatal disruption of D1R-SynGAP complex causes cognitive deficits in adulthood. GABA, SynGAP
27  2020 Reciprocal cross-sensitization of D1 and D3 receptors following pharmacological stimulation in the hemiparkinsonian rat. AIMs, D3R, DA, PD
28  2020 Recovery of BDNF and CB1R in the Prefrontal Cortex Underlying Improvement of Working Memory in Prenatal DEHP-Exposed Male Rats after Aerobic Exercise. BDNF, CB1R, DEHP, FAAH
29  2020 Signaling models for dopamine-dependent temporal contiguity in striatal synaptic plasticity. AC1, CaMKII, DA, PKA, RP
30  2020 SKF83959, an agonist of phosphatidylinositol-linked dopamine receptors, prevents renewal of extinguished conditioned fear and facilitates extinction. BDNF, CREB, D1 receptor, PI
31  2020 Specific Hippocampal Interneurons Shape Consolidation of Recognition Memory. LTP, NOR
32  2019 5alpha-reductase inhibitors dampen L-DOPA-induced dyskinesia via normalization of dopamine D1-receptor signaling pathway and D1-D3 receptor interaction. 5AR, DUTA, ERK, FIN, LID, PD
33  2019 A novel dopamine D1 receptor agonist excites delay-dependent working memory-related neuronal firing in primate dorsolateral prefrontal cortex. DA, DLPFC
34  2019 Advances in Dopamine D1 Receptor Ligands for Neurotherapeutics. ---
35  2019 Balance between dopamine and adenosine signals regulates the PKA/Rap1 pathway in striatal medium spiny neurons. A2AR, D2R, MSNs, PKA
36  2019 Biased G Protein-Independent Signaling of Dopamine D1-D3 Receptor Heteromers in the Nucleus Accumbens. D3R
37  2019 Competitive ability during mate competition relates to unique patterns of dopamine-related gene expression in the social decision-making network of male zebra finches. DA, HCA, LCA
38  2019 D1 receptor hypersensitivity in mice with low striatal D2 receptors facilitates select cocaine behaviors. D2R
39  2019 Defining Structure-Functional Selectivity Relationships (SFSR) for a Class of Non-Catechol Dopamine D1 Receptor Agonists. GPCRs, SFSR
40  2019 Differential enhancement of ERK, PKA and Ca2+ signaling in direct and indirect striatal neurons of Parkinsonian mice. AMPA, DA, ERK, PD, PKA
41  2019 Disruption of SynGAP-dopamine D1 receptor complexes alters actin and microtubule dynamics and impairs GABAergic interneuron migration. GABA, SynGAP
42  2019 Distinct roles of striatal direct and indirect pathways in value-based decision making. D2R
43  2019 Divergent medial amygdala projections regulate approach-avoidance conflict behavior. ---
44  2019 Dopamine D1 and D2 receptors mediate analgesic and hypnotic effects of l-tetrahydropalmatine in a mouse neuropathic pain model. EEG, l-THP, PSNL
45  2019 Dopamine D1 and D3 receptor modulators restore morphine analgesia and prevent opioid preference in a model of neuropathic pain. D3R, SCI
46  2019 Dopamine D1 Receptor (D1R) Expression Is Controlled by a Transcriptional Repressor Complex Containing DISC1. DISC1, KLF16
47  2019 Dopamine D1-like receptors in the dorsomedial prefrontal cortex regulate contextual fear conditioning. dmPFC, NAc, VH
48  2019 Effects of Electroacupuncture on Expression of D1 Receptor (D1R), Phosphorylation of Extracellular-Regulated Protein Kinase 1/2 (p-ERK1/2), and c-Fos in the Insular Cortex of Ketamine-Addicted Rats. EA, IC, KET, NS
49  2019 GPR88 in D1R-Type and D2R-Type Medium Spiny Neurons Differentially Regulates Affective and Motor Behavior. KO
50  2019 Human Autoantibodies Against N-Methyl-D-Aspartate Receptor Modestly Alter Dopamine D1 Receptor Surface Dynamics. ---
51  2019 Hypoactivity of the lateral habenula contributes to negative symptoms and cognitive dysfunction of schizophrenia in rats. COX, DAergic, DRN, LHb, mPFC, TH, TPH2
52  2019 Morphine Differentially Alters the Synaptic and Intrinsic Properties of D1R- and D2R-Expressing Medium Spiny Neurons in the Nucleus Accumbens. D2R, mEPSC, mIPSC, MSNs
53  2019 Opiate-associated contextual memory formation and retrieval are differentially modulated by dopamine D1 and D2 signaling in hippocampal-prefrontal connectivity. CPP, CREB, D2R, DA, ERK, GSK-3, mPFC, vHIP
54  2019 PET radioligands for the dopamine D1-receptor: Application in psychiatric disorders. D2R, DA, PET
55  2019 Phosphorylation of Npas4 by MAPK Regulates Reward-Related Gene Expression and Behaviors. BDNF, CREB, DA, MAPK, MSNs, NAc, Npas4, PKA, WT
56  2019 Role of Helix 8 in Dopamine Receptor Signaling. D2R, GPCRs
57  2019 Striatal overexpression of beta-arrestin2 counteracts L-dopa-induced dyskinesia in 6-hydroxydopamine lesioned Parkinson's disease rats. FFT, L-dopa, LID, MSNs
58  2019 Targeting the receptor-based interactome of the dopamine D1 receptor: looking for heteromer-selective drugs. GPCRs
59  2019 The allosteric dopamine D1 receptor potentiator, DETQ, ameliorates subchronic phencyclidine-induced object recognition memory deficits and enhances cortical acetylcholine efflux in male humanized D1 receptor knock-in mice. NOR, PAMs
60  2019 The Fat Mass and Obesity-Associated Protein (FTO) Regulates Locomotor Responses to Novelty via D2R Medium Spiny Neurons. D2-MSNs, FTO, GPe
61  2019 Three divisions of the mouse caudal striatum differ in the proportions of dopamine D1 and D2 receptor-expressing cells, distribution of dopaminergic axons, and composition of cholinergic and GABAergic interneurons. D2R
62  2019 Transient Chemogenetic Inhibition of D1-MSNs in the Dorsal Striatum Enhances Methamphetamine Self-Administration. CaMKII, CNO, DREADDs
63  2019 Type 2beta Corticotrophin Releasing Factor Receptor Forms a Heteromeric Complex With Dopamine D1 Receptor in Living Cells. CRF, CRF2alpha, GPCR
64  2018 A Schizophrenia-Related Deletion Leads to KCNQ2-Dependent Abnormal Dopaminergic Modulation of Prefrontal Cortical Interneuron Activity. D2R, DA, E/I, PV, SCZ
65  2018 Baicalin reverses the impairment of synaptogenesis induced by dopamine burden via the stimulation of GABAAR-TrkB interaction in minimal hepatic encephalopathy. BAI, GABAAR, MHE
66  2018 cJun N-terminal kinase (JNK) mediates cortico-striatal signaling in a model of Parkinson's disease. DARPP-32, JNK, NMDA, PD
67  2018 Differential and Overlapping Pattern of Foxp1 and Foxp2 Expression in the Striatum of Adult Mouse Brain. D2R, SPNs
68  2018 Differential behavioral phenotypes of dopamine D1 receptor knockdown mice at the embryonic, postnatal, and adult stages. KD, KO
69  2018 Differential Dopamine D1 and D3 Receptor Modulation and Expression in the Spinal Cord of Two Mouse Models of Restless Legs Syndrome. D3R, RLS, WT
70  2018 Distinctive Changes of L-Type Calcium Channels and Dopamine Receptors in the Dorsomedial and Dorsolateral Striatum after the Expression of Habitual Cocaine-Seeking Behavior in Rats. D2R, DA, DLS, DMS, DS, FI, LTCCs, SA
71  2018 Dopamine D1 receptor-mediated upregulation of BKCa currents modifies Muller cell gliosis in a rat chronic ocular hypertension model. COH, DA, GFAP
72  2018 Gs-versus Golf-dependent functional selectivity mediated by the dopamine D1 receptor. Golf, Gs
73  2018 Hyperactive Response of Direct Pathway Striatal Projection Neurons to L-dopa and D1 Agonism in Freely Moving Parkinsonian Mice. DA, PD, Pitx3Null
74  2018 In Utero Exposure to Fine Particulate Matter Causes Hypertension Due to Impaired Renal Dopamine D1 Receptor in Offspring. GRK4, ROS
75  2018 Is dopamine D1 receptor availability related to social behavior? A positron emission tomography replication study. PET, SSP
76  2018 Large-scale transcriptomic analysis reveals that pridopidine reverses aberrant gene expression and activates neuroprotective pathways in the YAC128 HD mouse. BDNF, GR, HD, mHTT
77  2018 Muscarinic M4 Receptors on Cholinergic and Dopamine D1 Receptor-Expressing Neurons Have Opposing Functionality for Positive Reinforcement and Influence Impulsivity. 5-CSRTT, CPP, IEG, M4Rs, PRs
78  2018 Nucleus accumbens controls wakefulness by a subpopulation of neurons expressing dopamine D1 receptors. NAc
79  2018 Parkinson's Disease-Linked LRRK2-G2019S Mutation Alters Synaptic Plasticity and Promotes Resilience to Chronic Social Stress in Young Adulthood. CSDS, LRRK2, LTP, PD, SPNs
80  2018 Prefronto-cortical dopamine D1 receptor sensitivity can critically influence working memory maintenance during delayed response tasks. DA, PFC, WM
81  2018 Region-specific changes in markers of neuroplasticity revealed in HIV-1 transgenic rats by low-dose methamphetamine. ERK, MAPK, NA, Tg, VP
82  2018 Signal transduction in L-DOPA-induced dyskinesia: from receptor sensitization to abnormal gene expression. LID, SPN
83  2018 Transcriptomic context of DRD1 is associated with prefrontal activity and behavior during working memory. PFC, SNPs, WM
84  2018 Trx-1 ameliorates learning and memory deficits in MPTP-induced Parkinson's disease model in mice. CREB, MPTP, MWM, NR2B, PD, SNpc, Tg, TH, Trx-1
85  2017 Anatomical and molecular characterization of dopamine D1 receptor-expressing neurons of the mouse CA1 dorsal hippocampus. ---
86  2017 Antagonism of Muscarinic Acetylcholine Receptors Alters Synaptic ERK Phosphorylation in the Rat Forebrain. ACh, ERK, mAChR, mPFC
87  2017 Characterizing the differential roles of striatal 5-HT1A auto- and hetero-receptors in the reduction of l-DOPA-induced dyskinesia. 5-HT1AR, LID, PD
88  2017 Dopamine D1 receptor agonist treatment attenuates extinction of morphine conditioned place preference while increasing dendritic complexity in the nucleus accumbens core. CPP, NAc
89  2017 Dopamine D1 Receptor Immunoreactivity on Fine Processes of GFAP-Positive Astrocytes in the Substantia Nigra Pars Reticulata of Adult Mouse. GFAP, SNr
90  2017 Effect of optogenetic manipulation of accumbal medium spiny neurons expressing dopamine D2 receptors in cocaine-induced behavioral sensitization. D2R, D2R-MSNs, DA, MSNs, NAc
91  2017 Effects of pair bonding on dopamine D1 receptors in monogamous male titi monkeys (Callicebus cupreus). ---
92  2017 Extinction of Contextual Cocaine Memories Requires Cav1.2 within D1R-Expressing Cells and Recruits Hippocampal Cav1.2-Dependent Signaling Mechanisms. CPP, PSD
93  2017 Fyn Signaling Is Compartmentalized to Dopamine D1 Receptor Expressing Neurons in the Dorsal Medial Striatum. D2R, DLS, DMS, FLEX, MSNs, NAc
94  2017 GSK-3beta Interacts with Dopamine D1 Receptor to Regulate Receptor Function: Implication for Prefrontal Cortical D1 Receptor Dysfunction in Schizophrenia. PFC
95  2017 Levodopa/Benserazide Loaded Microspheres Alleviate L-dopa Induced Dyskinesia through Preventing the Over-Expression of D1R/Shp-2/ERK1/2 Signaling Pathway in a Rat Model of Parkinson's Disease. CDS, L-dopa, LID, PD
96  2017 Long-term treatment with dopamine D3 receptor agonists induces a behavioral switch that can be rescued by blocking the dopamine D1 receptor. RLS
97  2017 Nicotine-induced and D1-receptor-dependent dendritic remodeling in a subset of dorsolateral striatum medium spiny neurons. DLS, DMS, MSNs
98  2017 Novel Dopamine Therapeutics for Cognitive Deficits in Schizophrenia. DLPFC
99  2017 Parallel role for the dopamine D1 receptor in gambling and amphetamine reinforcement in healthy volunteers. AMPH, FLU, HAL
100  2017 Striatal dopamine D1 receptor suppression impairs reward-associative learning. AAV, DA, shRNA