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Abbreviation : DA
Long Form : decursinol angelate
No. Year Title Co-occurring Abbreviation
2019 Bio- Fortification of Angelica gigas Nakai Nano-Powder Using Bio-Polymer by Hot Melt Extrusion to Enhance the Bioaccessibility and Functionality of Nutraceutical Compounds. AA, AGN, AGNC, DeltaH, DPPH, DSC, EAGN, FAGN, FRAP, FTIR, HME, HP, HPMC, Tg
2019 Decursin and Decursinol Angelate Suppress Adipogenesis through Activation of beta-catenin Signaling Pathway in Human Visceral Adipose-Derived Stem Cells. ACC, ADM, AGN, ASCs, FAS, GSK, PPARgamma, VAT
2019 Decursinol angelate ameliorates 12-O-tetradecanoyl phorbol-13-acetate (TPA) -induced NF-kappaB activation on mice ears by inhibiting exaggerated inflammatory cell infiltration, oxidative stress and pro-inflammatory cytokine production. TPA
2019 Decursinol Angelate Ameliorates Dextran Sodium Sulfate-Induced Colitis by Modulating Type 17 Helper T Cell Responses. DSS, Th17
2019 Rapid and Efficient Separation of Decursin and Decursinol Angelate from Angelica gigas Nakai using Ionic Liquid, (BMIm)BF4, Combined with Crystallization. A. gigas, DW, ILs, RSM
2018 Decursin and decursinol angelate: molecular mechanism and therapeutic potential in inflammatory diseases. ---
2018 Decursinol Angelate Inhibits LPS-Induced Macrophage Polarization through Modulation of the NFkappaB and MAPK Signaling Pathways. iNOS, LPS, NOX, PMA
2018 Development of Resveratrol-Loaded Herbal Extract-Based Nanocomposites and Their Application to the Therapy of Ovarian Cancer. NPs, RSV
2018 Polydopamine-coated nanocomposites of Angelica gigas Nakai extract and their therapeutic potential for triple-negative breast cancer cells. NCs, PD, UV, XPS
10  2018 Simultaneous Determination of Decursin, Decursinol Angelate, Nodakenin, and Decursinol of Angelica gigas Nakai in Human Plasma by UHPLC-MS/MS: Application to Pharmacokinetic Study. AGN
11  2017 Fabrication of polymer matrix-free nanocomposites based on Angelica gigas Nakai extract and their application to breast cancer therapy. NCs
12  2017 Natural Korean Medicine Dang-Gui: Biosynthesis, Effective Extraction and Formulations of Major Active Pyranocoumarins, Their Molecular Action Mechanism in Cancer, and Other Biological Activities. AGN, ROS
13  2017 Prostate Cancer Xenograft Inhibitory Activity and Pharmacokinetics of Decursinol, a Metabolite of Angelica gigas Pyranocoumarins, in Mouse Models. AGN, AR, AUC, TRAMP
14  2016 Decursinol angelate inhibits PGE2-induced survival of the human leukemia HL-60 cell line via regulation of the EP2 receptor and NFkappaB pathway. PGE2
15  2016 Nanocomposites based on Soluplus and Angelica gigas Nakai extract fabricated by an electrohydrodynamic method for oral administration. AGN, AGN, EHD, NCs, SP, XRD
16  2016 Omega-3 fatty acids incorporated colloidal systems for the delivery of Angelica gigas Nakai extract. AGN, EXT, ME
17  2016 Pyranocoumarin Tissue Distribution, Plasma Metabolome and Prostate Transcriptome Impacts of Sub-Chronic Exposure to Korean Angelica Supplement in Mice. AGN
18  2015 Angelica gigas Nakai and Soluplus-Based Solid Formulations Prepared by Hot-Melting Extrusion: Oral Absorption Enhancing and Memory Ameliorating Effects. AGN, EXT, HME
19  2015 Cancer Chemoprevention with Korean Angelica: Active Compounds, Pharmacokinetics, and Human Translational Considerations. AGN, PK
20  2015 Chemopreventive Effects of Korean Angelica versus Its Major Pyranocoumarins on Two Lineages of Transgenic Adenocarcinoma of Mouse Prostate Carcinogenesis. AGN, DLP, NECA, TRAMP
21  2015 Cytochrome P450 Isoforms in the Metabolism of Decursin and Decursinol Angelate from Korean Angelica. ABT, CES, HLM, PK
22  2015 Single oral dose pharmacokinetics of decursin and decursinol angelate in healthy adult men and women. AGN
23  2012 A synthetic decursin analog with increased in vivo stability suppresses androgen receptor signaling in vitro and in vivo. AR, DPTC, PCa, PSA
24  2012 Anti-cancer and other bioactivities of Korean Angelica gigas Nakai (AGN) and its major pyranocoumarin compounds. AGN
25  2012 Overexpression of cinnamate 4-hydroxylase gene enhances biosynthesis of decursinol angelate in Angelica gigas hairy roots. AgPAL, CaMV
26  2012 Quantitative determination of decursin, decursinol angelate, and decursinol in mouse plasma and tumor tissue using liquid-liquid extraction and HPLC. LLOQ
27  2011 Protective effects of decursin and decursinol angelate against amyloid beta-protein-induced oxidative stress in the PC12 cell line: the role of Nrf2 and antioxidant enzymes. AD
28  2010 Decursinol angelate blocks transmigration and inflammatory activation of cancer cells through inhibition of PI3K, ERK and NF-kappaB activation. ECM, MMP
29  2009 In vivo anti-cancer activity of Korean Angelica gigas and its major pyranocoumarin decursin. AGN, LLC
30  2008 In vitro inhibitory potential of decursin and decursinol angelate on the catalytic activity of cytochrome P-450 1A1/2, 2D15, and 3A12 isoforms in canine hepatic microsomes. DC
31  2007 Decursin and decursinol angelate inhibit estrogen-stimulated and estrogen-independent growth and survival of breast cancer cells. ER
32  2007 Transport of decursin and decursinol angelate across Caco-2 and MDR-MDCK cell monolayers: in vitro models for intestinal and blood-brain barrier permeability. BBB, DE, Ly