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Abbreviation : DAGLalpha
Long Form : diacylglycerol lipase alpha
No. Year Title Co-occurring Abbreviation
2020 Adolescent binge-ethanol accelerates cognitive impairment and β-amyloid production and dysregulates endocannabinoid signaling in the hippocampus of APP/PSE mice. AD, CB2, ECS, EtOH, MAGL
2020 An optimized spectrophotometric assay reveals increased activity of enzymes involved in 2-arachidonoyl glycerol turnover in the cerebral cortex of a rat model of Alzheimer's disease. 2-AG, 4-NPB, AD, MAGL
2020 Bisphenol A Deranges the Endocannabinoid System of Primary Sertoli Cells with an Impact on Inhibin B Production. BPA, eCB, TRPV1
2020 Brain region-dependent changes in the expression of endocannabinoid-metabolizing enzymes in rats following antidepressant drugs. eCB, FAAH, MAGL, NAPE-PLD
2020 Hypoxia training improves hepatic steatosis partly by downregulation of CB1 receptor in obese mice. 2-AG, AEA, ATGL, CPT-1, ECS, HT, MAGL, PPARgamma, SREBP-1
2020 Impact of tetrahydrocannabinol on the endocannabinoid 2-arachidonoylglycerol metabolism: ABHD6 and ABHD12 as novel players in human placenta. 2-AG, ABHD6, AEA, MAGL
2019 Diacylglycerol Lipase-Alpha Regulates Hippocampal-Dependent Learning and Memory Processes in Mice. 2-AG, MWM
2019 Early intervention with electroacupuncture prevents PTSD-like behaviors in rats through enhancing hippocampal endocannabinoid signaling. BDNF, CB1R, EA, ESPS, PSD-95, PTSD, shRNA, SYN
2019 Glucose Increase DAGLalpha Levels in Tanycytes and Its Inhibition Alters Orexigenic and Anorexigenic Neuropeptides Expression in Response to Glucose. 2-AG, AEA, ARC, ECS
10  2019 Repetitive high-frequency transcranial magnetic stimulation reverses depressive-like behaviors and protein expression at hippocampal synapses in chronic unpredictable stress-treated rats by enhancing endocannabinoid signaling. CB1R, CUS, ECS, rMS, rTMS
11  2018 The Endocannabinoid System across Postnatal Development in Transmembrane Domain Neuregulin 1 Mutant Mice. ABHD6, CB1R, MGLL, NRG-1, PNDs
12  2016 A chemical proteomic atlas of brain serine hydrolases identifies cell type-specific pathways regulating neuroinflammation. eCB
13  2016 A novel live cell assay to measure diacylglycerol lipase alpha activity. 2-AG, CB, DAGL, DiFMUO, eCB, PNPB
14  2016 Cocaine-induced behavioral sensitization decreases the expression of endocannabinoid signaling-related proteins in the mouse hippocampus. CB1, NAPE-PLD
15  2016 Identification of an endocannabinoid system in the rat pars tuberalis-a possible interface in the hypothalamic-pituitary-adrenal system? ACTH, COX-2, CRF, ECs, FAAH, IR, NAPE-PLD, POMC, PT
16  2016 Regulated endosomal trafficking of Diacylglycerol lipase alpha (DAGLalpha) generates distinct cellular pools; implications for endocannabinoid signaling. 2-AG, eCB
17  2015 A natural substrate-based fluorescence assay for inhibitor screening on diacylglycerol lipase α. 2-AG
18  2015 Anxiety, Stress, and Fear Response in Mice With Reduced Endocannabinoid Levels. 2-AG
19  2015 Cannabinoid-induced chemotaxis in bovine corneal epithelial cells. 2-AG, B-CECs, CECs, MAPK, WIN
20  2015 Comprehensive Analysis of Structure-Activity Relationships of alpha-Ketoheterocycles as sn-1-Diacylglycerol Lipase alpha Inhibitors. 2-AG
21  2015 Inhibiting endocannabinoid biosynthesis: a novel approach to the treatment of constipation. 2-AG, GI
22  2015 Modulation of sweet taste sensitivities by endogenous leptin and endocannabinoids in mice. CT, DIO, LA
23  2014 Discovery of glycine sulfonamides as dual inhibitors of sn-1-diacylglycerol lipase alpha and alpha/beta-hydrolase domain 6. ABHD6, ABPP
24  2014 Genetic disruption of 2-arachidonoylglycerol synthesis reveals a key role for endocannabinoid signaling in anxiety modulation. 2-AG, eCB
25  2014 Nuclear diacylglycerol lipase-alpha in rat brain cortical neurons: evidence of 2-arachidonoylglycerol production in concert with phospholipase C-beta activity. 2-AG, LC-MS, PLCbeta
26  2013 Developmental pattern of diacylglycerol lipase-alpha (DAGLalpha) immunoreactivity in brain regions important for song learning and control in the zebra finch (Taeniopygia guttata). ---
27  2013 Diacylglycerol lipasealpha (DAGLalpha) and DAGLbeta cooperatively regulate the production of 2-arachidonoyl glycerol in autaptic hippocampal neurons. 2-AG, DSE
28  2013 Subcellular localization of NAPE-PLD and DAGL-alpha in the ventromedial nucleus of the hypothalamus by a preembedding immunogold method. NAPE-PLD, VMH
29  2011 Distribution of diacylglycerol lipase alpha, an endocannabinoid synthesizing enzyme, in the rat forebrain. 2-AG, FAAH, MAGL
30  2011 Endocannabinoids generated by Ca2+ or by metabotropic glutamate receptors appear to arise from different pools of diacylglycerol lipase. eCBs, GPCRs
31  2011 Endocannabinoids regulate the migration of subventricular zone-derived neuroblasts in the postnatal brain. 2-AG, eCB, RMS
32  2010 Effects of cannabinoids and cannabinoid-enriched Cannabis extracts on TRP channels and endocannabinoid metabolic enzymes. ACU, BDS, CBC, CBD, CBG, CBN, FAAH, MAGL, NAAA, THCVA, TRP
33  2010 Loss of retrograde endocannabinoid signaling and reduced adult neurogenesis in diacylglycerol lipase knock-out mice. 2-AG, eCBs
34  2010 The constitutive production of the endocannabinoid 2-arachidonoylglycerol participates in oligodendrocyte differentiation. 2-AG, MAGL, OPCs
35  2010 Tonic modulation of spinal hyperexcitability by the endocannabinoid receptor system in a rat model of osteoarthritis pain. 2-AG, MIA, NAPE-PLD, OA, WDR
36  2008 Tetrahydrolipstatin analogues as modulators of endocannabinoid 2-arachidonoylglycerol metabolism. 2-AG, FAAH, MAGL
37  2007 Compartmentalization of endocannabinoids into lipid rafts in a dorsal root ganglion cell line. 2-AG, AEA
38  2006 Localization of diacylglycerol lipase-alpha around postsynaptic spine suggests close proximity between production site of an endocannabinoid, 2-arachidonoyl-glycerol, and presynaptic cannabinoid CB1 receptor. 2-AG