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Abbreviation : DBTC
Long Form : dibutyltin dichloride
No. Year Title Co-occurring Abbreviation
2022 Methods of a New Chronic Pancreatitis and Spontaneous Pancreatic Cancer Mouse Model Using Retrograde Pancreatic Duct Injection of Dibutyltin Dichloride. CP
2022 YAP activates pancreatic stellate cells and enhances pancreatic fibrosis. alpha-SMA, Ccn1, CP, PSCs, TGF-beta1, YAP
2021 Role of NLR family pyrin domain-containing 3 inflammasome in the activation of pancreatic stellate cells. CP, PSCs
2021 Simulated gastric hydrolysis and developmental toxicity of dibutyltin bis(2-ethylhexyl thioglycolate) in rats. DBTE, DBTEC, GD5, NMR, NOAEL
2020 Adipose‑derived mesenchymal stem cells ameliorate dibutyltin dichloride‑induced chronic pancreatitis by inhibiting the PI3K/AKT/mTOR signaling pathway. ASCs, CP
2019 Decreased Glutamatergic Synaptic Strength in the Periaqueductal Gray Contributes to Maintenance of Visceral Pain in Male Rats with Experimental Pancreatitis. vlPAG
2018 Increased heat shock protein 70 expression attenuates pancreatic fibrosis induced by dibutyltin dichloride. HSP
2018 Inhibiting autophagy promotes collagen degradation by regulating matrix metalloproteinases in pancreatic stellate cells. CP, ECM
2017 Amygdalin improves microcirculatory disturbance and attenuates pancreatic fibrosis by regulating the expression of endothelin-1 and calcitonin gene-related peptide in rats. alpha-SMA, CGRP, CP, ET-1, PDGF-BB, PSCs, TGF-beta1
10  2017 Influence of daily oral prophylactic selenium treatment on the dibutyltin dichloride (DBTC)-induced pancreatitis in rats. BW, ERCP, MDA, p.o
11  2016 Inflammatory stimuli promote growth and invasion of pancreatic cancer cells through NF-kappaB pathway dependent repression of PP2Ac. LPS, MCM, NF-kappaB, PP2A, PP2Ac
12  2016 Multiorgan chronic inflammatory hepatobiliary pancreatic murine model deficient in tumor necrosis factor receptors 1 and 2. ---
13  2016 Pathophysiology of chronic pancreatitis induced by dibutyltin dichloride joint ethanol in mice. FN, MMP-1, TIMP-1
14  2016 [Effect of DaChaiHu Decoction on pancreatic fibrosis induced by DBTC combined with alcohol and the mechanism of TGF-beta/Smad signaling pathway]. CON group, CP, DCHD group, TGF-beta
15  2016 [The role of oxidative inflammatory cascade on pancreatic fibrosis progression in mice induced by DBTC plus ethanol]. CP, MDA, MPO, SOD
16  2015 Expression of Smad7 and Smad ubiquitin regulatory factor 2 in a rat model of chronic pancreatitis. alpha-SMA, CP, PSC, RT-PCR, Smurf2, TGF
17  2014 A sustained prostacyclin analog, ONO-1301, attenuates pancreatic fibrosis in experimental chronic pancreatitis induced by dibutyltin dichloride in rats. CP, HGF, PSCs
18  2013 Protective effects of edaravone on experimental chronic pancreatitis induced by dibutyltin dichloride in rats. alpha-SMA, CP, MDA, NF, PSCs, SOD
19  2013 Reduction of fibrosis in dibutyltin dichloride-induced chronic pancreatitis using rat umbilical mesenchymal stem cells from Wharton's jelly. CP, UC-MSCs
20  2012 Effect of taurine on acinar cell apoptosis and pancreatic fibrosis in dibutyltin dichloride-induced chronic pancreatitis. TUNEL
21  2012 Gene expression profiling and endothelin in acute experimental pancreatitis. DRG, ET
22  2012 Treatment of pancreatic fibrosis with siRNA against a collagen-specific chaperone in vitamin A-coupled liposomes. aPSCs, FACS
23  2011 Comparison of antioxidative and antifibrotic effects of alpha-tocopherol with those of tocotrienol-rich fraction in a rat model of chronic pancreatitis. CP, TGF-beta1, TRF
24  2010 Analgesic effects of gabapentin on mechanical hypersensitivity in a rat model of chronic pancreatitis. ---
25  2010 Attenuation of persistent experimental pancreatitis pain by a bradykinin b2 receptor antagonist. BK
26  2010 Bone marrow-derived pancreatic stellate cells in rats. BM, EGFP, PSCs
27  2010 Reversal of pancreatitis-induced pain by an orally available, small molecule interleukin-6 receptor antagonist. DRG, IL-6
28  2008 An organotin mixture found in polyvinyl chloride (PVC) pipe is not immunotoxic to adult Sprague-Dawley rats. DMTC, EPA, MBT, MMT, PVC
29  2008 Developmental Exposure to 1.0 or 2.5 mg/kg of Dibutyltin Dichloride Does Not Impair Immune Function in Sprague-Dawley Rats. BW, DTH, GD, NK, PND, PVC
30  2008 Immune responses in sprague-dawley rats exposed to dibutyltin dichloride in drinking water as adults. BW, DTH, NK, PVC
31  2008 RAS inhibitors decrease apoptosis of acinar cells and increase elimination of pancreatic stellate cells after in the course of experimental chronic pancreatitis induced by dibutyltin dichloride. CP, PSCs
32  2007 Ascorbic acid alleviates pancreatic damage induced by dibutyltin dichloride (DBTC) in rats. CP, MDA, SOD
33  2007 NADPH oxidase plays a crucial role in the activation of pancreatic stellate cells. DPI, PSCs, ROS
34  2007 Oral administration of taurine improves experimental pancreatic fibrosis. ---
35  2007 Role of fibrosis-related genes and pancreatic duct obstruction in rat pancreatitis models: implications for chronic pancreatitis. BDL
36  2007 Treatment of inflamed pancreas with enkephalin encoding HSV-1 recombinant vector reduces inflammatory damage and behavioral sequelae. cDNA, ENK, HSV-1, met-ENK, RANTES, VEH
37  2006 Influence of selenium treatment on the acute toxicity of dibutyltin dichloride in rats. MDA
38  2005 Anti-monocyte chemoattractant protein 1 gene therapy attenuates experimental chronic pancreatitis induced by dibutyltin dichloride in rats. MCP-1
39  2005 Interleukin-4 gene transfer into rat pancreas by recombinant adenovirus. Adbeta-gal, IL, RT-PCR
40  2004 Camostat mesilate attenuates pancreatic fibrosis via inhibition of monocytes and pancreatic stellate cells activity. CM, MCP-1, PSCs, TNF-alpha
41  2004 In vivo characterization of developing chronic pancreatitis in rats. ---
42  2003 Comparison of hepatotoxicity and metabolism of butyltin compounds in the liver of mice, rats and guinea pigs. TBTC
43  2003 Effects of butyltin compounds on mitochondrial respiration and its relation to hepatotoxicity in mice and Guinea pigs. TBTC
44  2003 Immunologic characterization of acute pancreatitis in rats induced by dibutyltin dichloride (DBTC). ---
45  2002 Dibutyltin dichloride modifies amylase release from isolated rat pancreatic acini. PKC
46  2002 Electron microscopic detection of tin accumulation in biliopancreatic concrements after induction of chronic pancreatitis in rats by di-n-butyltin dichloride. AAS, EDX, EELS, ESI
47  2002 Identification by DNA macroarray of nur77 as a gene induced by di-n-butyltin dichloride: its role in organotin-induced apoptosis. TBTC
48  2002 Organotin-induced apoptosis occurs in small CD4(+)CD8(+) thymocytes and is accompanied by an increase in RNA synthesis. TBTC
49  2002 Persistence of memory type lymphocytes in an experimental model of chronic pancreatitis in rats. RT-PCR
50  2002 The role of monocyte chemoattractant protein-1 in experimental chronic pancreatitis model induced by dibutyltin dichloride in rats. MCP-1
51  2001 Cytokine mRNA levels and lymphocyte infiltration in pancreatic tissue during experimental chronic pancreatitis induced by dibutyltin dichloride. ---
52  2001 Heat shock response is associated with protection against acute interstitial pancreatitis in rats. HSPs, TGF-beta1
53  2001 Repeated administration of a mild acute toxic dose of di-n-butyltin dichloride at intervals of 3 weeks induces severe lesions in pancreas and liver of rats. i.v
54  2000 Antidotal effects of 2,3-dimercaptopropane-1-sulfonic acid (DMPS) and meso-2,3-dimercaptosuccinic acid (DMSA) on the organotoxicity of dibutyltin dichloride (DBTC) in rats. DMPS, DMSA
55  2000 Organotins induce apoptosis by disturbance of [Ca(2+)](i) and mitochondrial activity, causing oxidative stress and activation of caspases in rat thymocytes. ROS, TBTC
56  1999 Some sulfur-containing metabolites of tri-n-butyltin chloride in male rats. MBTC, T3CO, TBTC, TBTO
57  1999 The course of pancreatic fibrosis induced by dibutyltin dichloride (DBTC). ---
58  1998 Organotin-induced apoptosis as observed in vitro is not relevant for induction of thymus atrophy at antiproliferative doses. TBTC
59  1998 The influence of ethanol on long-term effects of dibutyltin dichloride (DBTC) in pancreas and liver of rats. ---
60  1997 Acute interstitial pancreatitis in rats induced by dibutyltin dichloride (DBTC): pathogenesis and natural course of lesions. ---
61  1997 Effect of SKF-525A on liver metabolism and hepatotoxicity of tri- and dibutyltin compounds in mice. MBTC, TBTC, TCOOH
62  1996 Collection and analysis of butyltin compounds in air at nanogram-per-cubic-meter levels. MBTC, TBTC
63  1995 Dysmorphogenic effects of di-n-butyltin dichloride in cultured rat embryos. ---
64  1995 Role of cytochrome P450 in hepatotoxicity induced by di- and tributyltin compounds in mice. PB, TBTC
65  1995 The SCID-hu mouse as a tool in immunotoxicological risk assessment: effects of 2-acetyl-4(5)-tetrahydroxybutyl-imidazole (THI) and di-n-butyltin dichloride (DBTC) on the human thymus in SCID-hu mice. THI
66  1995 The thymus atrophy-inducing organotin compound DBTC inhibits the binding of thymocytes to thymic epithelial cells. TEC
67  1994 Cellular and molecular aspects of organotin-induced thymus atrophy. ---
68  1994 Comparison of hepatotoxicity caused by mono-, di- and tributyltin compounds in mice. MBTC, TBTC
69  1994 Selective inhibition of immature CD4-CD8+ thymocyte proliferation, but not differentiation, by the thymus atrophy-inducing compound di-n-butyltin dichloride. PHA
70  1994 Ultracytochemistry of thymic epithelial cells in rats given organotin. ---
71  1993 Recovery from chemically induced thymus atrophy starts with CD4- CD8- CD2high TcR alpha beta-/low thymocytes and results in an increased formation of CD4- CD8- TcR alpha beta high thymocytes. TCR
72  1992 Acute toxicity of tri-n-butyltin chloride (TBTC) in the Syrian golden hamster. TBTC
73  1992 The organotin-induced thymus atrophy, characterized by depletion of CD4+ CD8+ thymocytes, is preceded by a reduction of the immature CD4- CD8+ TcR alpha beta-/low CD2high thymoblast subset. TCR
74  1989 Acute pancreatitis and bile duct lesions in rat induced by dibutyltin dichloride. ---
75  1989 Organotin-induced thymus atrophy concerns the OX-44+ immature thymocytes. Relation to the interaction between early thymocytes and thymic epithelial cells? ---
76  1988 Dibutyltin and tributyltin compounds induce thymus atrophy in rats due to a selective action on thymic lymphoblasts. MBTC, TBTC
77  1985 Meso-2,3-dimercaptosuccinic acid increases the inhibition of glutathione S-transferase activity from rat liver cytosol supernatants by di-n-butyltin dichloride. TCHTC
78  1983 Di-n-butyltindichloride uncouples oxidative phosphorylation in rat liver mitochondria. ---
79  1982 Comparative toxicity of alkyltin and estertin stabilizers. CBETC, CETC, CMETC, DOTC
80  1980 Immunotoxic effects of dialkyltins used for stabilization of plastics. DOTC
81  1980 Toxicity of organotin compounds in chicken and rats. DMTC, DOTC
82  1979 Lymphocytotoxicity and immunosuppression by organotin compounds. Suppression of graft-versus-host reactivity, blast transformation, and E-rosette formation by di-n-butyltindichloride and di-n-octyltindichloride. DOTC