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Abbreviation : DMN
Long Form : dimethylnitrosamine
No. Year Title Co-occurring Abbreviation
2020 A novel model of non-alcoholic steatohepatitis with fibrosis and carcinogenesis in connexin 32 dominant-negative transgenic rats. Cx32, GST-P, HFD, IR, MCDD, NASH, WT
2020 Determination of atmospheric amines at Seoul, South Korea via gas chromatography/tandem mass spectrometry. DEA, DEN, DMA, ECF, HS-SPME, MRM, NDEA, NDMA, NPF, SOA
2020 Effects of Fuzheng Huayu recipe on entecavir pharmacokinetics in normal and dimethylnitrosamine-induced hepatic fibrosis rats. CHB, ETV, FZHY
2020 Fugan Wan alleviates hepatic fibrosis by inhibiting ACE/Ang II/AT-1R signaling pathway and enhancing ACE2/Ang 1-7/Mas signaling pathway in hepatic fibrosis rat models. ACE2, AT1R, ERK, FGW, HE, p-c-Jun, pERK, qRT-PCR, TGF-beta1
2020 MR-Based Electrical Conductivity Imaging of Liver Fibrosis in an Experimental Rat Model. ANOVA, ROI
2020 Selonsertib Inhibits Liver Fibrosis via Downregulation of ASK1/ MAPK Pathway of Hepatic Stellate Cells. alpha-SMA, ASK1, HSCs, JNK, MAPK
2019 A novel role of glutathione S-transferase A3 in inhibiting hepatic stellate cell activation and rat hepatic fibrosis. alpha-SMA, FN, GSK-3beta, GSTA3, HSCs, JNK, MDA, p38 MAPK, ROS, WB
2019 Down-regulation of LncRNA UCA1 alleviates liver injury in rats with liver cirrhosis. ALT, AST, lncRNA HULC, MDA, NC, SOD
2019 Fuzhenghuayu Decoction ameliorates hepatic fibrosis by attenuating experimental sinusoidal capillarization and liver angiogenesis. FZHY, HHSEC, HUVEC
10  2019 Graptopetalum paraguayense Inhibits Liver Fibrosis by Blocking TGF-beta Signaling In Vivo and In Vitro. DEN, ECM, GP
11  2019 Influence of resveratrol on liver fibrosis induced by dimethylnitrosamine in male rats. ALP, AST, MDA
12  2019 Protective effect of cultured bear bile powder against dimethylnitrosamine-induced hepatic fibrosis in rats. CBBP, DHA, EPA, PPARs
13  2019 Short-term detection of gastric genotoxicity using the DNA double-strand break marker gamma-H2AX. DMAB, DMH, MNU, pga5
14  2019 The protective effect of Pentoxifylline on testopathy in male rats following Dimethyl Nitrosamine administration: An experimental study. PX
15  2019 Yinchenhao decoction suppresses rat liver fibrosis involved in an apoptosis regulation mechanism based on network pharmacology and transcriptomic analysis. TCM, TdT, YCHD
16  2018 Biochemical and Molecular Mechanisms of Platelet-Rich Plasma in Ameliorating Liver Fibrosis Induced by Dimethylnitrosurea. alpha-SMA, PRP
17  2018 Decoy receptor 3 alleviates hepatic fibrosis through suppressing inflammation activated by NF-kappaB signaling pathway. DcR3, ELISA, i.p, qRT-PCR, TL1A
18  2018 Evaluation of Hepatoprotective Effect of Curcumin on Liver Cirrhosis Using a Combination of Biochemical Analysis and Magnetic Resonance-Based Electrical Conductivity Imaging. ---
19  2018 Gallic Acid Attenuates Dimethylnitrosamine-Induced Liver Fibrosis by Alteration of Smad Phosphoisoform Signaling in Rats. GA
20  2018 Hepatoprotective Principles and Other Chemical Constituents from the Mycelium of Phellinus linteus. HSCs, PLE
21  2018 S-allyl-glutathione improves experimental liver fibrosis by regulating Kupffer cell activation in rats. COL1A1, DAS, HSCs, HSP47, KCs, SAG
22  2018 Salvianolate Reduces Glucose Metabolism Disorders in Dimethylnitrosamine-Induced Cirrhotic Rats. alpha-SMA, AUC, FINS, FPG, GIR, HE, Hyp, OGTT
23  2018 Yinchenhao Decoction Alleviates Liver Fibrosis by Regulating Bile Acid Metabolism and TGF-beta/Smad/ERK Signalling Pathway. CDCA, HSCs, YCHD
24  2018 Zinc oxide nanoparticles inhibit dimethylnitrosamine induced liver injury in rat. ALT, AST, LDH, Zn-MT
25  2017 Antifibrotic effect of total flavonoids of Astmgali Radix on dimethylnitrosamine-induced liver cirrhosis in rats. FXR, HE, PCR, PPARgamma, TFA, UCP2
26  2017 Antioxidant, antiapoptotic and amino acid balance regulating activities of 1,7-dihydroxy-3,4,8-trimethoxyxanthone against dimethylnitrosamine-induced liver fibrosis. alpha-SMA, CIV, HA, Hyp, TGF-1beta
27  2017 beta-Amyrin, a pentacyclic triterpene, exhibits anti-fibrotic, anti-inflammatory, and anti-apoptotic effects on dimethyl nitrosamine-induced hepatic fibrosis in male rats. TIMP-1, TNF-alpha
28  2017 Bovine milk-derived alpha-lactalbumin prevents hepatic fibrosis induced by dimethylnitrosamine via nitric oxide pathway in rats. alpha-LA
29  2017 Capsaicin Inhibits Dimethylnitrosamine-Induced Hepatic Fibrosis by Inhibiting the TGF-beta1/Smad Pathway via Peroxisome Proliferator-Activated Receptor Gamma Activation. CPS, HSCs
30  2017 Differential Proteomic Analysis of Dimethylnitrosamine (DMN)-Induced Liver Fibrosis. iTRAQ
31  2017 Effect of Yi Guan Jian decoction on differentiation of bone marrow mesenchymalstem cells into hepatocyte-like cells in dimethylnitrosamine-induced liver cirrhosis in mice. BMSCs, CXCR4, HLCs, YGD
32  2017 Expression of pro-fibrotic and anti-fibrotic molecules in dimethylnitrosamine-induced hepatic fibrosis. alpha-SMA, CTGF, ECM, KO, mTOR, PPARgamma, TGF-beta, WT
33  2017 Herbal Formula, Baogan Yihao (BGYH), Prevented Dimethylnitrosamine(DMN)-Induced Liver Injury in Rats. BGYH
34  2017 N-nitrosamines induced infertility and hepatotoxicity in male rabbits. 17beta-HSD, CAT, DEN, DPN, GR, MEN, SOD, TBARS
35  2017 Oxidative stress, histopathological and electron microscopic alterations induced by dimethylnitrosamine in renal male mice and the protective effect of alpha-lipoic acid. ALA
36  2017 Protective effect of alpha-lipoic acid against spleen toxicity of dimethylnitrosamine in male mice: Antioxidant and ultrastructure approaches. ALA
37  2017 Structural transition of kidney cystatin in dimethylnitrosamine-induced renal cancer in rats: identification as a novel biomarker for kidney cancer and prognosis. CD, CRKC, RKC
38  2017 Temsirolimus induced structural transition of cancerous renal cystatin to normal form in rats: In vitro mechanistic approach underlying renal cancer prevention. CD, mRCC, RCCs
39  2017 The photodissociation of N,N-dimethylnitrosamine at 355 nm: The effect of excited-state conformational changes on product vector correlations. ---
40  2016 Adenovirus-mediated expression of orphan nuclear receptor NR4A2 targeting hepatic stellate cell attenuates liver fibrosis in rats. ECM, HSCs
41  2016 Chinese medicine CGA formula ameliorates DMN-induced liver fibrosis in rats via inhibiting MMP2/9, TIMP1/2 and the TGF-beta/Smad signaling pathways. CS-PS, FZHY
42  2016 Comparison of TGF-beta, PDGF, and CTGF in hepatic fibrosis models using DMN, CCl4, and TAA. TAA
43  2016 Dicliptera Chinensis polysaccharides target TGF-beta/Smad pathway and inhibit stellate cells activation in rats with dimethylnitrosamine-induced hepatic fibrosis. DCP, HF, HSCs
44  2016 Dioscin alleviates dimethylnitrosamine-induced acute liver injury through regulating apoptosis, oxidative stress and inflammation. ---
45  2016 Ethyl Acetate Fraction of Amomum xanthioides Exerts Antihepatofibrotic Actions via the Regulation of Fibrogenic Cytokines in a Dimethylnitrosamine-Induced Rat Model. CTGF, EFAX, PDGF-beta, TGF-beta
46  2016 Fibroblast growth factor 21 attenuates hepatic fibrogenesis through TGF-beta/smad2/3 and NF-kappaB signaling pathways. FGF21, HSCs
47  2016 Glycoproteomics analysis of plasma proteins associated with Opisthorchis viverrini infection-induced cholangiocarcinoma in hamster model. Con A, FETUB, NDRG1, NSFL1C, OV
48  2016 Hepatoprotective effects of Dicliptera chinensis polysaccharides on dimethylnitrosamine-induced hepatic fibrosis rats and its underlying mechanism. ALB, AST, Col I, DCP, HA, HF, IL-6, LN, NF-kappaB, TBIL, TGF-beta l, TNF-alpha
49  2016 Hepatoprotective effects of zingerone on carbon tetrachloride- and dimethylnitrosamine-induced liver injuries in rats. MAPKs, NF-kappaB
50  2016 Huangqi decoction alleviates dimethylnitrosamine-induced liver fibrosis: An analysis of bile acids metabolic mechanism. AS, CDCA, GA, HQD, HSCs, TCM
51  2016 Localization of Xenobiotic Transporter OCTN1/SLC22A4 in Hepatic Stellate Cells and Its Protective Role in Liver Fibrosis. ERGO
52  2016 Novel matrine derivative MD-1 attenuates hepatic fibrosis by inhibiting EGFR activation of hepatic stellate cells. EGFR, HSCs, MT
53  2016 Protective effects of Centellaasiatica leaf extract on dimethylnitrosamine‑induced liver injury in rats. DW, IL
54  2016 Serum Metabolomic Characterization of Liver Fibrosis in Rats and Anti-Fibrotic Effects of Yin-Chen-Hao-Tang. lysoPCs, PLS-DA, UPLC-TOF-MS, YCHT
55  2016 Swertiamarin Attenuates Experimental Rat Hepatic Fibrosis by Suppressing Angiotensin II-Angiotensin Type 1 Receptor-Extracellular Signal-Regulated Kinase Signaling. Ang II, AT1R, ERK, HSCs, RAS, Swe
56  2016 Synergistic anti-liver fibrosis actions of total astragalus saponins and glycyrrhizic acid via TGF-beta1/Smads signaling pathway modulation. AST, BDL, CCK-8, GA, HQD, Hyp
57  2016 The Dimethylnitrosamine Induced Liver Fibrosis Model in the Rat. AST
58  2016 Thyroid and reproductive hormones disruption as well as kallikrein-3 level in dimethyl nitrosamine-induced toxicity: Effects of ascorbate treatment in male wistar rats. LH, TSH, TST
59  2016 Umbilical cord-derived mesenchymal stem cells alleviate liver fibrosis in rats. IL, KCs, UC-MSCs
60  2016 [Effect of Fuzheng Huayu capsule on serum metabolomics in rats with liver fibrosis induced by dimethylnitrosamine]. FHC, PCA, PLS-DA
61  2015 Actions of Huangqi decoction against rat liver fibrosis: a gene expression profiling analysis. DEGs, HQD, Hyp, PPI
62  2015 An HNF1alpha-regulated feedback circuit modulates hepatic fibrogenesis via the crosstalk between hepatocytes and hepatic stellate cells. BDL, HNF1alpha, HSCs, SHP-1
63  2015 Anticancer Activity of Atractylodes lancea (Thunb.) DC in a Hamster Model and Application of PET-CT for Early Detection and Monitoring Progression of Cholangiocarcinoma. 18F-FDG, CCA, OV, PET-CT
64  2015 Antifibrotic effects of luteolin on hepatic stellate cells and liver fibrosis by targeting AKT/mTOR/p70S6K and TGFbeta/Smad signalling pathways. BDL, HSCs, PDGF, TGF-beta1
65  2015 Combination of sorafenib and gadolinium chloride (GdCl3) attenuates dimethylnitrosamine(DMN)-induced liver fibrosis in rats. HSCs, Hyp, KCs, SECs, vWF
66  2015 Comparative pharmacokinetic and tissue distribution profiles of four major bioactive components in normal and hepatic fibrosis rats after oral administration of Fuzheng Huayu recipe. AMY, DSS, FZHY, ROS, SAB, SFDA
67  2015 Diethylnitrosamine (DEN)-induced carcinogenic liver injury in mice. DEN
68  2015 Evaluation of a repeated dose liver micronucleus assay in rats treated with two genotoxic hepatocarcinogens, dimethylnitrosamine and 2-acetylaminofluorene: the possibility of integrating micronucleus tests with multiple tissues into a repeated dose general toxicity study. 2-AAF, BM, CSGMT, GI, JEMS, MMS, MN, RDLMN
69  2015 Hepatoprotective effect of juglone on dimethylnitrosamine-induced liver fibrosis and its effect on hepatic antioxidant defence and the expression levels of alpha-SMA and collagen III. Col, HSCs, SOD
70  2015 Herbal formula, Scutellariae radix and Rhei rhizoma attenuate dimethylnitrosamine-induced liver fibrosis in a rat model. SR
71  2015 Protective effect of theaflavin-enriched black tea extracts against dimethylnitrosamine-induced liver fibrosis in rats. alpha-SMA, GOT, GPT, HCC, SD, TF-BTE, TGF-beta1
72  2015 Reduction of Dimethylnitrosamine-Induced Liver Fibrosis by the Novel Gene Regulator PI Polyamide Targeting Transforming Growth Factor beta1 Gene. AP-1, PCR, PI, TGF-beta
73  2015 [Effect of Fuzheng Huayu recipe on CYP450 isozymes in normal and liver fibrosis rats]. CYP450, FZHY
74  2015 [Role of opisthorchis felineus on induction of bile duct cancer]. ---
75  2014 Acute liver injury induced by low dose dimethylnitrosamine alters mediators of hepatic vascular flow. HSC, NO, vWF
76  2014 Alleviation of Dimethylnitrosamine-Induced Liver Injury and Fibrosis by Supplementation of Anabasis articulata Extract in Rats. CAT, GR, IL-10, MDA, NO, TGF-beta1
77  2014 Bioactive compound reveals a novel function for ribosomal protein S5 in hepatic stellate cell activation and hepatic fibrosis. BDL, de, HSCs, RPS5
78  2014 Dimethylnitrosamine-induced reduction in the level of poly-ADP-ribosylation of histone proteins of blood lymphocytes--a sensitive and reliable biomarker for early detection of cancer. PAR
79  2014 Early detection of liver fibrosis in rats using 3-D ultrasound Nakagami imaging: a feasibility evaluation. ---
80  2014 Effect of Fuzheng Huayu capsule combined with Pegasys on genotype 1 hepatitis C fibrosis and cell apoptosis. ---
81  2014 Effects of beta-sitosterol derived from Artemisia capillaris on the activated human hepatic stellate cells and dimethylnitrosamine-induced mouse liver fibrosis. alpha-SMA, HSC, TGF-beta
82  2014 Hepatoprotective effects of loach (Misgurnus anguillicaudatus) lyophilized powder on dimethylnitrosamine-induced liver fibrosis in rats. ALB, alpha-SMA, ALT, AST, CIV, ECM, HA, HSCs, Hyp, LN, MMP-2, MMP-9, PCIII, TGF-beta1, TIMP-1, TP
83  2014 Lactoferrin protects against chemical-induced rat liver fibrosis by inhibiting stellate cell activation. ColIalpha-1, LF
84  2014 Liposomal oxymatrine in hepatic fibrosis treatment: formulation, in vitro and in vivo assessment. ---
85  2014 Pin1 induction in the fibrotic liver and its roles in TGF-beta1 expression and Smad2/3 phosphorylation. alpha-SMA, AP-1, ERK, HSC, MEF, RT-PCR, TGF-beta1
86  2014 Protective effects of garcinol on dimethylnitrosamine-induced liver fibrosis in rats. alpha-SMA, AST, ECM, TGF-beta1
87  2014 The role of phospholipase D1 in liver fibrosis induced by dimethylnitrosamine in vivo. MEA, PLD
88  2014 Two xanthones from Swertia punicea with hepatoprotective activities in vitro and in vivo. ALB, ALT, APAP, AST, LDH, MDA, ROS, SOD, TBIL
89  2014 Whey-hydrolyzed peptide-enriched immunomodulating diet prevents progression of liver cirrhosis in rats. IMD
90  2014 [Reverse effect of Yinchenhao decoction in dimethyl nitrosamine-induced hepatic fibrosis in rats]. AST, CIV, HA, LN, YCHD
91  2014 [Role of zinc finger protein 1 in rat liver fibrosis and as related to TGFb expression]. TGFb
92  2013 (18)F-FBHGal for asialoglycoprotein receptor imaging in a hepatic fibrosis mouse model. ASGPR
93  2013 A new style of dimethylnitrosamine induced fulminant hepatitis in mice. ---
94  2013 Effect of sinapic acid against dimethylnitrosamine-induced hepatic fibrosis in rats. TGF-beta1
95  2013 Evaluation of chemicals requiring metabolic activation in the EpiDerm™ 3D human reconstructed skin micronucleus (RSMN) assay. 4NQO, BaP, CP, DBA, DMBA, ECVAM, RSMN
96  2013 Graptopetalum paraguayense ameliorates chemical-induced rat hepatic fibrosis in vivo and inactivates stellate cells and Kupffer cells in vitro. alpha-SMA, GP, HSCs, MGP
97  2013 High-frequency ultrasound imaging to evaluate liver fibrosis progression in rats and yi guan jian herbal therapeutic effects. YGJ
98  2013 Investigation of metabolite alteration in dimethylnitrosamine-induced liver fibrosis by GC-MS. AST
99  2013 Non-invasive assessment of liver fibrosis in a rat model: shear wave elasticity imaging versus real-time elastography. LF, RTE, SWEI
100  2013 Phyto-power dietary supplement potently inhibits dimethylnitrosamine-induced liver fibrosis in rats. alpha-SMA, MMP2, TGF-beta1