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Abbreviation : EBP50
Long Form : ezrin-radixin-moesin-binding phosphoprotein 50
No. Year Title Co-occurring Abbreviation
2019 Ezrin-Radixin-Moesin Binding Phosphoprotein 50: A Potential Novel Biomarker in Human Papilloma Virus-Associated Head and Neck Squamous Cell Carcinomas. HNSCC, HR-HPV
2018 EBP50 suppresses the proliferation of MCF-7 human breast cancer cells via promoting Beclin-1/p62-mediated lysosomal degradation of c-Myc. ---
2017 Ezrin-Radixin-Moesin Binding Phosphoprotein 50 (EBP50) Suppresses the Metastasis of Breast Cancer and HeLa Cells by Inhibiting Matrix Metalloproteinase-2 Activity. MMP-2
2017 Reduced EBP50 expression levels are correlated with unfavorable clinicopathological features of extrahepatic bile duct carcinoma and promote the proliferation and migration of QBC939 cells. CC, si
2016 Binding of EBP50 to Nox organizing subunit p47phox is pivotal to cellular reactive species generation and altered vascular phenotype. Ang II, LPS, NOX, NoxO1, ROS, VSMC
2016 EBP50 interacts with EGFR and regulates EGFR signaling to affect the prognosis of cervical cancer patients. CC, CNV, EGFR
2016 Ezrin-radixin-moesin-binding phosphoprotein-50 regulates EGF-induced AKT activation through interaction with EGFR and PTEN. EGFR, PDGFR, PTEN
2015 Different conformational dynamics of PDZ1 and PDZ2 in full-length EBP50 analyzed by hydrogen/deuterium exchange mass spectrometry. EB, HDX-MS, PDZ
2015 Phosphorylation of ezrin-radixin-moesin-binding phosphoprotein 50 (EBP50) by Akt promotes stability and mitogenic function of S-phase kinase-associated protein-2 (Skp2). Cip1, Skp2
10  2014 Reduced EBP50 expression or mis-localization of the EBP50 protein is associated with the malignant progression of esophageal squamous cell carcinoma. ESCC, LN
11  2013 Clinical significance of EBP50 overexpression assessed by quantum dot analysis in gastric cancer. GC, IHC, PDZ, QD
12  2013 Ezrin-radixin-moesin-binding phosphoprotein 50 (EBP50) and nuclear factor-kappaB (NF-kappaB): a feed-forward loop for systemic and vascular inflammation. NF-kappaB, VSMC
13  2013 Tumor suppressor function of ezrin-radixin-moesin-binding phosphoprotein-50 through beta-catenin/E-cadherin pathway in human hepatocellular cancer. CCK-8, HCC
14  2012 EBP50 gene transfection promotes 5-fluorouracil-induced apoptosis in gastric cancer cells through Bax- and Bcl-2-triggered mitochondrial pathways. 5-FU, RT-PCR
15  2012 EBP50 inhibits EGF-induced breast cancer cell proliferation by blocking EGFR phosphorylation. EGFR
16  2012 EBP50 promotes focal adhesion turnover and vascular smooth muscle cells migration. EGF, FAK, KO, VSMC, WT
17  2012 Loss of EBP50 stimulates EGFR activity to induce EMT phenotypic features in biliary cancer cells. EGFR
18  2012 Temporal and spatial regulation of ezrin-radixin-moesin-binding phosphoprotein-50-kDa (EBP50) during embryo implantation in mouse uterus. IS
19  2012 The detection of EBP50 expression using quantum dot immunohistochemistry in pancreatic cancer tissue and down-regulated EBP50 effect on PC-2 cells. PC
20  2012 The scaffolding protein EBP50 promotes vascular smooth muscle cell proliferation and neointima formation by regulating Skp2 and p21(cip1). Cip1, Cip1, cip1, cip1, KO, VSMC, WT
21  2011 EBP50 is involved in the regulation of vascular smooth muscle cell migration and cytokinesis. ---
22  2011 Ezrin and EBP50 redistribute apically in rat uterine epithelial cells at the time of implantation and in response to cell contact. UECs
23  2011 Immunohistochemical analysis of ezrin-radixin-moesin-binding phosphoprotein 50 in prostatic adenocarcinoma. BPH, HGPIN, Mets, NAC, NDP, PCa
24  2011 Proprotein convertase 5/6 is critical for embryo implantation in women: regulating receptivity by cleaving EBP50, modulating ezrin binding, and membrane-cytoskeletal interactions. PC, PC6
25  2010 A regulated complex of the scaffolding proteins PDZK1 and EBP50 with ezrin contribute to microvillar organization. ---
26  2010 EBP50 exerts tumor suppressor activity by promoting cell apoptosis and retarding extracellular signal-regulated kinase activity. ERK
27  2009 Ezrin-radixin-moesin-binding phosphoprotein (EBP50), an estrogen-inducible scaffold protein, contributes to biliary epithelial cell proliferation. ---
28  2007 Expression and clinicopathological significance of oestrogen-responsive ezrin-radixin-moesin-binding phosphoprotein 50 in breast cancer. RT-PCR
29  2007 The developmental regulation of CD81 in the rat retina. RPE, SAP97
30  2004 Distinct in vitro interaction pattern of dopamine receptor subtypes with adaptor proteins involved in post-endocytotic receptor targeting. GST, NSF, SNX1
31  2004 TRPC5 activation kinetics are modulated by the scaffolding protein ezrin/radixin/moesin-binding phosphoprotein-50 (EBP50). r5dV, rTRPC5
32  2003 Galphaq-coupled receptor internalization specifically induced by Galphaq signaling. Regulation by EBP50. GPCR
33  2003 Tissue-specific regulation by estrogen of ezrin and ezrin/radixin/moesin-binding protein 50. ---
34  2002 Epithelial inducible nitric-oxide synthase is an apical EBP50-binding protein that directs vectorial nitric oxide output. iNOS, NO
35  2002 Regulation of GTP-binding protein alpha q (Galpha q) signaling by the ezrin-radixin-moesin-binding phosphoprotein-50 (EBP50). Galpha q, PLC
36  2000 Evidence for ezrin-radixin-moesin-binding phosphoprotein 50 (EBP50) self-association through PDZ-PDZ interactions. ERM
37  1999 A PDZ-interacting domain in CFTR is an apical membrane polarization signal. CFTR
38  1998 The carboxyl-terminal region of EBP50 binds to a site in the amino-terminal domain of ezrin that is masked in the dormant molecule. ---