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Abbreviation : EC
Long Form : (-)-epicatechin
No. Year Title Co-occurring Abbreviation
2020 (-)-Epicatechin and NADPH oxidase inhibitors prevent bile acid-induced Caco-2 monolayer permeabilization through ERK1/2 modulation. DCA, GI, MLC, MLCP
2019 (-)-Epicatechin in the control of glucose homeostasis: Involvement of redox-regulated mechanisms. T2D
2019 (-)-Epicatechin mitigates radiation-induced intestinal injury and promotes intestinal regeneration via suppressing oxidative stress. ---
2019 A Sucrose-Induced MYB (SIMYB) Transcription Factor Promoting Proanthocyanidin Accumulation in the Tea Plant ( Camellia sinensis). bHLH, SIMYB, TFs, WDR
2019 Comprehensive NMR analysis of two kinds of post-fermented tea and their anti-glycation activities in vitro. EGC, EGCG, HSA, LAB, NMR
2019 Different inhibition properties of catechins on the individual subunits of mucosal alpha-glucosidases as measured by partially-purified rat intestinal extract. ECG, EGCG
2019 Effect of Stereochemical Configuration on the Transport and Metabolism of Catechins from Green Tea across Caco-2 Monolayers. BCRP, CG, ECG, EGC, EGCG, GCG, GTCs, MRP2
2019 Effect of tea catechin derivatives on stability of soybean oil/tea seed oil blend and oxidative stability of fried fish crackers during storage. EGCG
2019 Simultaneous determinations of four major bioactive components in Acacia catechu (L.f.) Willd and Scutellaria baicalensis Georgi extracts by LC-MS/MS: Application to its herb-herb interactions based on pharmacokinetic, tissue distribution and excretion studies in rats. ADME, BL, BLE, LLOQ, SBG
10  2019 Structure-activity relationship of procyanidins on advanced glycation end products formation and corresponding mechanisms. AGEs, NEG
11  2019 The inhibitory effects of an eight-herb formula (RCM-107) on pancreatic lipase: enzymatic, HPTLC profiling and in silico approaches. ECG, EGCG, HPTLC
12  2019 The mechanism of interactions between flavan-3-ols against a-glucosidase and their in vivo antihyperglycemic effects. ---
13  2019 Transport of Flavanolic Monomers and Procyanidin Dimer A2 across Human Adenocarcinoma Stomach Cells (MKN-28). ---
14  2019 Using Caffeine and Free Amino Acids To Enhance the Transepithelial Transport of Catechins in Caco-2 Cells. ECG, EGCG, MRP2, P-gp
15  2018 (-)-Epicatechin and its metabolites prevent palmitate-induced NADPH oxidase upregulation, oxidative stress and insulin resistance in HepG2 cells. ECM, T2D
16  2018 (-)-Epicatechin and the Colonic 2,3-Dihydroxybenzoic Acid Metabolite Regulate Glucose Uptake, Glucose Production, and Improve Insulin Signaling in Renal NRK-52E Cells. DHBA, DHPAA, HPPA, IR, IRS-1, VA
17  2018 (-)-Epicatechin protects the intestinal barrier from high fat diet-induced permeabilization: Implications for steatosis and insulin resistance. HFD, TJ
18  2018 Comparison of the sympathetic stimulatory abilities of B-type procyanidins based on induction of uncoupling protein-1 in brown adipose tissue (BAT) and increased plasma catecholamine (CA) in mice. BAT, CA, FL, UCP
19  2018 Green Tea Catechins: Their Use in Treating and Preventing Infectious Diseases. ECG, EGC, EGCG
20  2018 Lack of acute or chronic effects of epicatechin-rich and procyanidin-rich apple extracts on blood pressure and cardiometabolic biomarkers in adults with moderately elevated blood pressure: a randomized, placebo-controlled crossover trial. BP, NO, PCs
21  2018 Nanoemulsion delivery system of tea polyphenols enhanced the bioavailability of catechins in rats. EGC, EGCG, GCG, O/W, TP
22  2018 Protective effects of (-)-epicatechin and the colonic metabolite 3,4-dihydroxyphenylacetic acid against glucotoxicity-induced insulin signalling blockade and altered glucose uptake and production in renal tubular NRK-52E cells. DHPAA
23  2018 Reduction of Nepsilon-(carboxymethyl) lysine by (-)-epicatechin and (-)-epigallocatechin gallate: The involvement of a possible trapping mechanism by catechin quinones. EGCG
24  2017 (-)-Epicatechin attenuates high-glucose-induced inflammation by epigenetic modulation in human monocytes. HAT, HG
25  2017 (-)-Epicatechin regulates blood lipids and attenuates hepatic steatosis in rats fed high-fat diet. BW
26  2017 Effect of the A-Type Linkage on the Pharmacokinetics and Intestinal Metabolism of Litchi Pericarp Oligomeric Procyanidins. ---
27  2017 Epicatechin elicits MyoD-dependent myoblast differentiation and myogenic conversion of fibroblasts. ---
28  2017 Expression of Key Structural Genes of the Phenylpropanoid Pathway Associated with Catechin Epimerization in Tea Cultivars. RNA-Seq
29  2017 Inhibitory Activity of Catechin Metabolites Produced by Intestinal Microbiota on Proliferation of HeLa Cells. EGC, EGCG
30  2017 Polyphenols from Lonicera caerulea L. Berry Inhibit LPS-Induced Inflammation through Dual Modulation of Inflammatory and Antioxidant Mediators. C3G, IL, LPS, MAPK, MIP, MnSOD, NF-kappaB, TAK1
31  2017 Profiling and identification of (-)-epicatechin metabolites in rats using ultra-high performance liquid chromatography coupled with linear trap-Orbitrap mass spectrometer. DPIs, HREIC, MMDFs
32  2017 The proposed biosynthesis of procyanidins by the comparative chemical analysis of five Camellia species using LC-MS. EC-glucose, EGC, EGC-glucose, HPLC
33  2016 (-)-Epicatechin improves insulin sensitivity in high fat diet-fed mice. HFD, PTP1B, T2D
34  2016 A gradient based facile HPLC method for simultaneous estimation of antioxidants extracted from tea powder. ECG, EGCG, LOD, LOQ
35  2016 Anti-inflammatory actions of (-)-epicatechin in the adipose tissue of obese mice. ER, HFD, T2D, TNF-alpha, UPR
36  2016 Biological Activity of Japanese Quince Extract and Its Interactions with Lipids, Erythrocyte Membrane, and Human Albumin. CA, PC
37  2016 Cerebroprotection of flavanol (-)-epicatechin after traumatic brain injury via Nrf2-dependent and -independent pathways. Nrf2, ROS, TBI
38  2016 Crystallographic evidence for beta-cyclodextrin inclusion complexation facilitating the improvement of antioxidant activity of tea (+)-catechin and (-)-epicatechin. beta-CD
39  2016 Development of a UFLC-MS/MS method for the simultaneous determination of seven tea catechins in rat plasma and its application to a pharmacokinetic study after administration of green tea extract. ECG, EGC, EGCG, GC, GCG, MRM
40  2016 Enhancement of antioxidant activity of green tea epicatechins in beta-cyclodextrin cavity: Single-crystal X-ray analysis, DFT calculation and DPPH assay. CDs, ECG, EGC, EGCG
41  2016 Improving the sweet aftertaste of green tea infusion with tannase. ECG, EGC, EGCG
42  2016 Mechanism of Creaming Down Based on Chemical Characterization of a Complex of Caffeine and Tea Catechins. ECg, EGCG
43  2016 Onset of a hypotensive effect following ingestion of flavan 3-ols involved in the activation of adrenergic receptors. AR, eNOS, FL, HR, MBP, p-eNOS
44  2016 Procyanidin Promotes Translocation of Glucose Transporter 4 in Muscle of Mice through Activation of Insulin and AMPK Signaling Pathways. C3G, GLUT4
45  2016 Quantitative comparison of cancer and normal cell adhesion using organosilane monolayer templates: an experimental study on the anti-adhesion effect of green-tea catechins. ECG, EGCG, OMTs
46  2016 Reversed-phase liquid chromatographic analysis of hydrophobic interaction between proanthocyanidins and a C₈-alkyl compound in aqueous solution. OSA Na, RP
47  2016 Separation of catechins and O-methylated (-)-epigallocatechin gallate using polyamide thin-layer chromatography. ECG, EGC, EGCG, TLC
48  2016 The metabolome of [2-(14)C](-)-epicatechin in humans: implications for the assessment of efficacy, safety, and mechanisms of action of polyphenolic bioactives. ADME
49  2015 (-)-Epicatechin in the prevention of tumor necrosis alpha-induced loss of Caco-2 cell barrier integrity. IBD, NOX, TEER
50  2015 3-O-Acyl-epicatechins Increase Glucose Uptake Activity and GLUT4 Translocation through Activation of PI3K Signaling in Skeletal Muscle Cells. GLUT
51  2015 Bioactivity-guided fractionation of an antidiarrheal Chinese herb Rhodiola kirilowii (Regel) Maxim reveals (-)-epicatechin-3-gallate and (-)-epigallocatechin-3-gallate as inhibitors of cystic fibrosis transmembrane conductance regulator. CFTR, ECG, EGC, EGCG
52  2015 Cocoa flavonoids protect hepatic cells against high-glucose-induced oxidative stress: relevance of MAPKs. CPE, MAPKs, Nrf2
53  2015 Efficacy of prophylactic flavan-3-ol in permanent focal ischemia in 12-mo-old mice. Nrf2
54  2015 Molecular weight and galloylation affect grape seed extract constituents' ability to cross-link dentin collagen in clinically relevant time. CT, ECG, EGC, EGCG, FTIR, GSE
55  2015 Tea Flavanols Block Advanced Glycation of Lens Crystallins Induced by Dehydroascorbic Acid. AGEs, AsA, DAsA, ECG, EGC, EGCG
56  2014 (-)-Epicatechin mitigates high-fructose-associated insulin resistance by modulating redox signaling and endoplasmic reticulum stress. ---
57  2014 (-)-Epicatechin protects hemorrhagic brain via synergistic Nrf2 pathways. ICH, Nrf
58  2014 Catechin content and the degree of its galloylation in oolong tea are inversely correlated with cultivation altitude. ECG, EGC, EGCG
59  2014 Cocoa flavonoids attenuate high glucose-induced insulin signalling blockade and modulate glucose uptake and production in human HepG2 cells. CPE
60  2014 Determination of catechin content in representative Chinese tea germplasms. ECG, EGCG, GCG, TC
61  2014 Effects of catechin polyphenols and preparations from the plant-parasitic nematode Heterodera glycines on protease activity and behaviour in three nematode species. 5-FAM, CE, CG, CT-L, ECG, EGC, EGCG, GC, GCG
62  2014 Enhancement of energy expenditure following a single oral dose of flavan-3-ols associated with an increase in catecholamine secretion. AMPK, BAT, FL, PGC-1alpha, REE, UCP1
63  2014 Galloyl moieties enhance the dentin biomodification potential of plant-derived catechins. CG, CTs, ECG, EGC, EGCG, GCG, MMPs
64  2014 Membrane lipids protected from oxidation by red wine tannins: a proton NMR study. AAPH, DLiPC, ECG, EGCG, NMR
65  2014 Simultaneous detection of green tea catechins and gallic acid in human serum after ingestion of green tea tablets using ion-pair high-performance liquid chromatography with electrochemical detection. EGC, GA, HPLC, PTFE
66  2014 The antimicrobial possibilities of green tea. ECG, EGC, EGCG
67  2014 The cocoa flavanol (-)-epicatechin protects the cortisol response. GC
68  2014 Theobromine enhances absorption of cacao polyphenol in rats. TB
69  2014 Uptake and metabolism of (-)-epicatechin in endothelial cells. 3ME5S, 3ME7S, E3G, E3S
70  2013 Catabolism of (+)-catechin and (-)-epicatechin by rat intestinal microbiota. ---
71  2013 Cocoa flavonoids improve insulin signalling and modulate glucose production via AKT and AMPK in HepG2 cells. AMPK, CPE, IRS
72  2013 Development of rapid and simultaneous quantitative method for green tea catechins on the bioanalytical study using UPLC/ESI-MS. ECG, EGC, EGCG, IS
73  2013 Erythrocyte membrane transporters during human ageing: modulatory role of tea catechins. ECG, EGC, EGCG, NHE
74  2013 Green tea formulations with vitamin C and xylitol on enhanced intestinal transport of green tea catechins. ECG, EGC, EGCG
75  2013 Green tea phenolics inhibit butyrate-induced differentiation of colon cancer cells by interacting with monocarboxylate transporter 1. EGCG, HDACs, TSA
76  2013 Influence of phenolic compounds of Kangra tea [Camellia sinensis (L) O Kuntze] on bacterial pathogens and indigenous bacterial probiotics of Western Himalayas. ECG, EGC, EGCG, HPLC
77  2013 Oral administration of the flavanol (-)-epicatechin bolsters endogenous protection against focal ischemia through the Nrf2 cytoprotective pathway. CAM
78  2013 Tannase-converted green tea catechins and their anti-wrinkle activity in humans. EGC, GA, NGE, TGE
79  2013 The flavanol (-)-epicatechin and its metabolites protect against oxidative stress in primary endothelial cells via a direct antioxidant effect. HUVECs
80  2012 (-)-Epicatechin enhances etoposide-induced antileukaemic effect in rats with acute myeloid leukaemia. AML
81  2012 Characterization of creaming precipitate of tea catechins and caffeine in aqueous solution. ECg
82  2012 Development of an isocratic HPLC method for catechin quantification and its application to formulation studies. ECG, EGC, EGCG
83  2012 Epicatechin used in the treatment of intestinal inflammatory disease: an analysis by experimental models. PC
84  2012 Green tea extract as food antioxidant. Synergism and antagonism with alpha-tocopherol in vegetable oils and their colloidal systems. ESR, GTE, TOH
85  2012 In vitro and in situ evaluation of herb-drug interactions during intestinal metabolism and absorption of baicalein. CUR, PIP
86  2012 Influence of gallate and pyrogallol moieties on the intestinal absorption of (-)-epicatechin and (-)-epicatechin gallate. ECG, EGCG, GAO
87  2012 Methylation of catechins and procyanidins by rat and human catechol-O-methyltransferase: metabolite profiling and molecular modeling studies. COMT
88  2012 Pharmacokinetics and blood-brain barrier penetration of (+)-catechin and (-)-epicatechin in rats by microdialysis sampling coupled to high-performance liquid chromatography with chemiluminescence detection. CL, HPLC
89  2011 beta-carotene radical cation addition to green tea polyphenols. Mechanism of antioxidant antagonism in peroxidizing liposomes. BDE, DFT, ECG, EGC, EGCG, LC-MS, SERS
90  2011 Configurational studies of complexes of various tea catechins and caffeine in crystal state. CA, Cg
91  2011 Effect of girdling at various positions of 'Huang Zhi Xiang' tea tree (Camellia sinensis) on the contents of catechins and starch in fresh leaf. CG, ECG, EGC, EGCG, GC, SC, TC
92  2011 Effect of green tea powder (Camellia sinensis L. cv. Benifuuki) particle size on O-methylated EGCG absorption in rats; The Kakegawa Study. BGI, BGP, ECD, ECG, EGC, EGCG, EGCG3Me
93  2011 Epicatechin administration leads to necrotic cell death of rat leukaemia promyelocytes in vivo. ---
94  2011 Evaluation of the bitterness of green tea catechins by a cell-based assay with the human bitter taste receptor hTAS2R39. ECg, EGC, EGCG
95  2011 Flavanols from green tea and phenolic acids from coffee: critical quantitative evaluation of the pharmacokinetic data in humans after consumption of single doses of beverages. EGC, EGCG
96  2011 Mechanism of potentiation by tea epigallocatechin of contraction in porcine coronary artery: the role of protein kinase Cdelta-mediated CPI-17 phosphorylation. ECG, EGC, EGCG, PKCdelta
97  2011 Milk beta-lactoglobulin complexes with tea polyphenols. beta-LG, ECG, EGCG
98  2011 New cancer treatment strategy using combination of green tea catechins and anticancer drugs. EGCG
99  2010 Antileukemic action of (-)-epicatechin in the spleen of rats with acute myeloid leukemia. ---
100  2010 Beta-cyclodextrin/surface plasmon resonance detection system for sensing bitter-astringent taste intensity of green tea catechins. ECg, EGC, EGCG, SPR