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Abbreviation : EC
Long Form : Enzyme Commission
No. Year Title Co-occurring Abbreviation
2019 A Survey for Predicting Enzyme Family Classes Using Machine Learning Methods. ---
2019 Deep learning enables high-quality and high-throughput prediction of enzyme commission numbers. CNNs
2019 Exploring Enzyme Evolution from Changes in Sequence, Structure, and Function. ACE, SSGs
2019 Towards comprehensive annotation of Drosophila melanogaster enzymes in FlyBase. GO
2018 EClerize: A customized force-directed graph drawing algorithm for biological graphs with EC attributes. ---
2018 ECPred: a tool for the prediction of the enzymatic functions of protein sequences based on the EC nomenclature. ---
2018 Genetic repertoires of anaerobic microbiomes driving generation of biogas. BioMETHA, MiMaS
2018 Improved enzyme annotation with EC-specific cutoffs using DETECT v2. ---
2018 Representativeness of variation benchmark datasets. ---
10  2018 SimCAL: a flexible tool to compute biochemical reaction similarity. AUC
11  2018 Something special about CO-dependent CO2 fixation. ACS, CO, CODH, WL
12  2018 Transcriptome-wide identification of genes involved in Ascorbate-Glutathione cycle (Halliwell-Asada pathway) and related pathway for elucidating its role in antioxidative potential in finger millet (Eleusine coracana (L.)). BP, FPKM, GO
13  2017 A Computational Methodology to Overcome the Challenges Associated With the Search for Specific Enzyme Targets to Develop Drugs Against Leishmania major. ---
14  2017 Automatic single- and multi-label enzymatic function prediction by machine learning. ---
15  2017 Bile salt stimulated lipase: Inhibition by phospholipids and relief by phospholipase A2. BSSL, LPC, NMR, PC, PLA2
16  2017 Complementary Sources of Protein Functional Information: The Far Side of GO. KEGG
17  2017 ECDomainMiner: discovering hidden associations between enzyme commission numbers and Pfam domains. PDB
18  2017 From Gene Annotation to Function Prediction for Metagenomics. GO
19  2017 Sequencing and de novo assembly of visceral mass transcriptome of the critically endangered land snail Satsuma myomphala: Annotation and SSR discovery. COG, NGS, SSRs
20  2017 Tracing the Repertoire of Promiscuous Enzymes along the Metabolic Pathways in Archaeal Organisms. KEGG
21  2016 Characterising Complex Enzyme Reaction Data. ---
22  2016 Comparative Characterization of the Leaf Tissue of Physalis alkekengi and Physalis peruviana Using RNA-seq and Metabolite Profiling. GO, KEGG
23  2016 Comparative transcriptome analysis of Gastrodia elata (Orchidaceae) in response to fungus symbiosis to identify gastrodin biosynthesis-related genes. FPKM, GO, KEGG, KOids, TMM
24  2016 De novo assembly of the transcriptome of Aegiceras corniculatum, a mangrove species in the Indo-West Pacific region. KOG, nr
25  2016 Exploring the chemistry and evolution of the isomerases. ---
26  2016 Moleculo Long-Read Sequencing Facilitates Assembly and Genomic Binning from Complex Soil Metagenomes. JGI
27  2016 RNA-Seq mediated root transcriptome analysis of Chlorophytum borivilianum for identification of genes involved in saponin biosynthesis. GO, RPKM
28  2015 Analysis of expressed sequence tags from cDNA library of Fusarium culmorum infected barley (Hordeum vulgare L.) roots. EST, NCBI
29  2015 DomSign: a top-down annotation pipeline to enlarge enzyme space in the protein universe. ---
30  2015 Fragment profiling of low molecular weight heparins using reversed phase ion pair liquid chromatography-electrospray mass spectrometry. ESI-IT-TOF-MS, LMWHs, RPIP-HPLC, UFH
31  2015 Metabolome-scale de novo pathway reconstruction using regioisomer-sensitive graph alignments. ---
32  2015 Mitochondrial dysfunction mediated by cytoplasmic acidification results in pollen tube growth cessation in Pyrus pyrifolia. HPC
33  2015 The enzymatic nature of an anonymous protein sequence cannot reliably be inferred from superfamily level structural information alone. ---
34  2015 The lifestyle of prokaryotic organisms influences the repertoire of promiscuous enzymes. ---
35  2014 Estimation of protein function using template-based alignment of enzyme active sites. CSA, RMSD
36  2014 Exploring the biological and chemical complexity of the ligases. ---
37  2014 From sequence to enzyme mechanism using multi-label machine learning. SFLD
38  2014 Identification of Functionally Related Enzymes by Learning-to-Rank Methods. ---
39  2014 Identification of heat-related ESTs in moth bean through suppression subtraction hybridization. SSH
40  2014 Mining a database of single amplified genomes from Red Sea brine pool extremophiles-improving reliability of gene function prediction using a profile and pattern matching algorithm (PPMA). GO, INDIGO, PPM, PPMA, SAGs
41  2014 PIERO ontology for analysis of biochemical transformations: effective implementation of reaction information in the IUBMB enzyme list. GO
42  2014 Profiling the orphan enzymes. ---
43  2013 A genome scale metabolic network for rice and accompanying analysis of tryptophan, auxin and serotonin biosynthesis regulation under biotic stress. ---
44  2013 Accurate prediction of protein enzymatic class by N-to-1 Neural Networks. ---
45  2013 Characterizing the functional similarity of enzymes with high co-citation in interaction networks. ---
46  2013 DcGO: database of domain-centric ontologies on functions, phenotypes, diseases and more. GO
47  2013 De Novo transcriptome sequencing reveals important molecular networks and metabolic pathways of the plant, Chlorophytum borivilianum. CYP450, ESTs, GC, GO, KEGG, RPKM, SSR
48  2013 ECOH: an enzyme commission number predictor using mutual information and a support vector machine. ECOH
49  2013 Exploring the host parasitism of the migratory plant-parasitic nematode Ditylenchus destuctor by expressed sequence tags analysis. ESTs, GO
50  2013 Identification of key drought stress-related genes in the hyacinth bean. GO, nr, SSH
51  2013 Rapid identification of sequences for orphan enzymes to power accurate protein annotation. ---
52  2013 Transcriptome analysis based on next-generation sequencing of non-model plants producing specialized metabolites of biotechnological interest. GO, KEGG
53  2012 De novo sequencing and analysis of the Ulva linza transcriptome to discover putative mechanisms associated with its successful colonization of coastal ecosystems. ---
54  2012 EnzML: multi-label prediction of enzyme classes using InterPro signatures. ---
55  2012 Exploring the evolution of novel enzyme functions within structurally defined protein superfamilies. ---
56  2012 Is EC class predictable from reaction mechanism? k-NN, RF, SVM
57  2012 Relationship between global structural parameters and Enzyme Commission hierarchy: implications for function prediction. AAs
58  2011 Comparative analysis of expressed sequence tags (ESTs) between drought-tolerant and -susceptible genotypes of chickpea under terminal drought stress. ESTs, nr, RILs, SSH
59  2011 Cutoff Scanning Matrix (CSM): structural classification and function prediction by protein inter-residue distance patterns. CSM
60  2011 Purine biosynthesis in archaea: variations on a theme. IMG
61  2011 Support vector machine prediction of enzyme function with conjoint triad feature and hierarchical context. AAC, CTF, MCC, SVM, SVMHL
62  2011 TheViral MetaGenome Annotation Pipeline(VMGAP):an automated tool for the functional annotation of viral Metagenomic shotgun sequencing data. VMGAP
63  2011 Toward mechanistic classification of enzyme functions. ---
64  2010 Accurate protein structure annotation through competitive diffusion of enzymatic functions over a network of local evolutionary similarities. ---
65  2010 Co-evolution of metabolism and protein sequences. COG
66  2010 Deriving enzymatic and taxonomic signatures of metagenomes from short read data. SPs, TSPs
67  2010 Non-homologous isofunctional enzymes: a systematic analysis of alternative solutions in enzyme evolution. NISE
68  2010 Similarity perception of reactions catalyzed by oxidoreductases and hydrolases using different classification methods. HCA, KohNN, SVM
69  2009 Data mining of enzymes using specific peptides. DME, SPs
70  2009 E-zyme: predicting potential EC numbers from the chemical transformation pattern of substrate-product pairs. ---
71  2009 Effects of dietary N-acetylcysteine on the oxidative stress induced in tilapia (Oreochromis niloticus) exposed to a microcystin-producing cyanobacterial water bloom. GR, LPO, MCs, NAC, SOD
72  2009 Metal-MACiE: a database of metals involved in biological catalysis. ---
73  2009 Sequence and structural features of enzymes and their active sites by EC class. ---
74  2008 annot8r: GO, EC and KEGG annotation of EST datasets. EST, GO, KEGG
75  2008 Genome-scale classification of metabolic reactions and assignment of EC numbers with self-organizing maps. SOMs
76  2008 Protective role of vitamin E on the microcystin-induced oxidative stress in tilapia fish (Oreochromis niloticus). LPO, MCs
77  2008 The development of PIPA: an integrated and automated pipeline for genome-wide protein function annotation. COG, GO, PIPA
78  2007 Functional representation of enzymes by specific peptides. MEX, SPs
79  2006 Clustering of domains of functionally related enzymes in the interaction database PRECISE by the generation of primary sequence patterns. PDB
80  2006 Cognate ligand domain mapping for enzymes. ---
81  2005 EzCatDB: the Enzyme Catalytic-mechanism Database. PDB
82  2005 Genome annotation errors in pathway databases due to semantic ambiguity in partial EC numbers. DBs
83  2005 Predicting enzyme family classes by hybridizing gene product composition and pseudo-amino acid composition. ---
84  2005 Representativity of target families in the Protein Data Bank: impact for family-directed structure-based drug discovery. ---
85  2005 Structural and functional characterization of a 5,10-methenyltetrahydrofolate synthetase from Mycoplasma pneumoniae (GI: 13508087). 5-FTHF, ADP, ATP, MTHFS
86  2005 Supervised enzyme network inference from the integration of genomic data and chemical information. ---
87  2005 The cyclophilins. ---
88  2005 Using functional domain composition to predict enzyme family classes. ---
89  2004 Call for an enzyme genomics initiative. ---
90  2004 Computational assignment of the EC numbers for genomic-scale analysis of enzymatic reactions. OC
91  2004 Enzyme classification by ligand binding. ---
92  2004 Predicting enzyme family class in a hybridization space. ---
93  2003 How well is enzyme function conserved as a function of pairwise sequence identity? ---
94  2001 Divergence of function in sequence-related groups of Escherichia coli proteins. ---
95  2001 Evolution of function in protein superfamilies, from a structural perspective. ---
96  2000 A multiple alignment algorithm for metabolic pathway analysis using enzyme hierarchy. ---
97  2000 Inhibitory effect of a brain derived peptide preparation on the Ca++-dependent protease, calpain. MAP2-DTAF
98  1999 LIGAND database for enzymes, compounds and reactions. ---
99  1999 The relationship between protein structure and function: a comprehensive survey with application to the yeast genome. ---
100  1998 Molecular phylogeny as a basis for the classification of transport proteins from bacteria, archaea and eukarya. TC