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Abbreviation : EC
Long Form : embryonal carcinoma
No. Year Title Co-occurring Abbreviation
2018 Analysis of the Paternally-Imprinted DLK1-MEG3 and IGF2-H19 Tandem Gene Loci in NT2 Embryonal Carcinoma Cells Identifies DLK1 as a Potential Therapeutic Target. 5azaD, DLK1, DMRs, EOI, IGF2, lncRNA, LOI, MEG3, NT2, PGCs
2018 Brentuximab vedotin exerts profound antiproliferative and pro-apoptotic efficacy in CD30-positive as well as cocultured CD30-negative germ cell tumour cell lines. ADC, GCT, MMAE
2018 CD30-Redirected Chimeric Antigen Receptor T Cells Target CD30+ and CD30- Embryonal Carcinoma via Antigen-Dependent and Fas/FasL Interactions. CAR, CD30.CAR T cells, NSG, TGCT
2018 Clinical Outcome of Retroperitoneal Lymph Node Dissection after Chemotherapy in Patients with Pure Embryonal Carcinoma in the Orchiectomy Specimen. PC-RPLND
2018 Delayed male germ cell sex-specification permits transition into embryonal carcinoma cells with features of primed pluripotency. ---
2018 Differentiation-Dependent Regulation of Human Endogenous Retrovirus K Sequences and Neighboring Genes in Germ Cell Tumor Cells. GCTs, HERVs
2018 GCNF regulates OCT4 expression through its interactions with nuclear receptor binding elements in NCCIT cells. CRs, GCNF, NR
2018 Testicular germ cell tumors: revisiting a series in light of the new WHO classification and AJCC staging systems, focusing on challenges for pathologists. AJCC, LVI, NSTs, SEs, TE, TGCTs, WHO, YST
2017 A Sonic hedgehog coreceptor, BOC regulates neuronal differentiation and neurite outgrowth via interaction with ABL and JNK activation. NPCs, Shh
10  2017 Alternative Splicing Generates Different 5' UTRs in OCT4B Variants. ES
11  2017 Changes of glycoconjugate expression profiles during early development. CCI, ES, GSLs, SSEAs
12  2017 Distinct retinoic acid receptor (RAR) isotypes control differentiation of embryonal carcinoma cells to dopaminergic or striatopallidal medium spiny neurons. MSNs, RA, RAR
13  2017 Outcomes of surveillance versus adjuvant chemotherapy for patients with stage IA and IB nonseminomatous testicular germ cell tumors. CSI, LVI, NSGCT, RFS, RPLND
14  2017 Ovarian Embryonal Carcinoma in a Dog. CK
15  2017 Production of stable GFP-expressing neural cells from P19 embryonal carcinoma stem cells. ---
16  2017 Refractory testicular germ cell tumors are highly sensitive to the second generation DNA methylation inhibitor guadecitabine. 5-Aza, TGCTs
17  2017 Retinoic Acid Signaling in P19 Stem Cell Differentiation. DMSO, RA
18  2017 The bromodomain inhibitor JQ1 triggers growth arrest and apoptosis in testicular germ cell tumours in vitro and in vivo. TGCT
19  2017 Transcriptional Silencing of Moloney Murine Leukemia Virus in Human Embryonic Carcinoma Cells. ES, HIV-1, MLV, MPMV
20  2016 A Shh coreceptor Cdo is required for efficient cardiomyogenesis of pluripotent stem cells. ES, Shh
21  2016 BRG1 interacts with GLI2 and binds Mef2c gene in a hedgehog signalling dependent manner during in vitro cardiomyogenesis. Hh, mES
22  2016 Growth and Differentiation Factor 3 Is Transcriptionally Regulated by OCT4 in Human Embryonic Carcinoma Cells. GDF3, TGCTs
23  2016 High-resolution telomere fluorescence in situ hybridization reveals intriguing anomalies in germ cell tumors. ALT, FISH, GCNIS, TGCT
24  2016 Hypermethylation of genes in testicular embryonal carcinomas. DMRs, IHC
25  2016 Identification of Novel Fusion Genes in Testicular Germ Cell Tumors. ES, TGCT
26  2016 Imprints and DPPA3 are bypassed during pluripotency- and differentiation-coupled methylation reprogramming in testicular germ cell tumors. NSE, PGC, SE, TE, TGCTs, YST
27  2016 MAPK15 upregulation promotes cell proliferation and prevents DNA damage in male germ cell tumors. GCT
28  2016 Selenophosphate synthetase 1 is an essential protein with roles in regulation of redox homoeostasis in mammals. GLRX1, GSTO1, ROS, SPS
29  2016 SOX2 is essential for in vivo reprogramming of seminoma-like TCam-2 cells to an embryonal carcinoma-like fate. GCC
30  2016 Testis peritubular myoid cells increase their motility and express matrix-metalloproteinase 9 (MMP-9) after interaction with embryonal carcinoma cells. EC cells, MMP-9, PTCs, TNF-alpha
31  2016 The association between institution at orchiectomy and outcomes on active surveillance for clinical stage I germ cell tumours. AS, CS, GCT, HR, OR
32  2015 A conjugate of octamer-binding transcription factor 4 and toll-like receptor 7 agonist prevents the growth and metastasis of testis embryonic carcinoma. T7-OCT4
33  2015 BMP Inhibition in Seminomas Initiates Acquisition of Pluripotency via NODAL Signaling Resulting in Reprogramming to an Embryonal Carcinoma. CIS, GCC
34  2015 Cisplatin resistance in germ cell tumours: models and mechanisms. GCT, HR
35  2015 Mediastinal Germ Cell Tumor Exhibiting a Discrepancy between Tumor Markers and Imaging: A Case Study. CC, GCT, hCG
36  2015 RAR/RXR binding dynamics distinguish pluripotency from differentiation associated cis-regulatory elements. PrE, RARs
37  2015 Selective ROS-dependent p53-associated anticancer effects of the hypoxoside derivative rooperol on human teratocarcinomal cancer stem-like cells. CSCs, ROS
38  2015 The role of spermatogenesis-associated protein 6 in testicular germ cell tumors. Bcl, FCM, SPATA6, TGCTs
39  2014 Asynchronous transcriptional silencing of individual retroviral genomes in embryonic cells. MMLV
40  2014 E-cadherin is critical for SC1-induced colony growth of F9 embryonic carcinoma cells. ES
41  2014 Efficient and simple production of insulin-producing cells from embryonal carcinoma stem cells using mouse neonate pancreas extract, as a natural inducer. IPCs, MPE
42  2014 Genomic screening of testicular germ cell tumors from monozygotic twins. MZ, TGCTs
43  2014 Induced pluripotency enables differentiation of human nullipotent embryonal carcinoma cells N2102Ep. GCTs
44  2014 Nanog1 in NTERA-2 and recombinant NanogP8 from somatic cancer cells adopt multiple protein conformations and migrate at multiple M.W species. aa, ES, rNanogP8, WB
45  2014 Role of SOX2 in the etiology of embryonal carcinoma, based on analysis of the NCCIT and NT2 cell lines. GCC
46  2014 Selective anticancer effects of a synthetic flavagline on human Oct4-expressing cancer stem-like cells via a p38 MAPK-dependent caspase-3-dependent pathway. CSCs, MAPK, siRNA
47  2014 Testicular embryonal carcinoma: a morphologic study of 180 cases highlighting unusual and unemphasized aspects. ---
48  2014 The redox function of APE1 is involved in the differentiation process of stem cells toward a neuronal cell fate. APE1, hAT-MASC, NAC, ROS
49  2013 Aza-induced cardiomyocyte differentiation of P19 EC-cells by epigenetic co-regulation and ERK signaling. AZA, epi
50  2013 Design and biological evaluation of synthetic retinoids: probing length vs. stability vs. activity. ATRA, FTIR-MS
51  2013 DNA damage causes TP53-dependent coupling of self-renewal and senescence pathways in embryonal carcinoma cells. ---
52  2013 Effects of cannabinoids and related fatty acids upon the viability of P19 embryonal carcinoma cells. CB
53  2013 Heterochromatin protein 1gamma overexpression in P19 embryonal carcinoma cells elicits spontaneous differentiation into the three germ layers. EBs, ES, HP1, HPlgamma-P19
54  2013 Involvement of crosstalk between Oct4 and Meis1a in neural cell fate decision. 5hmC, ChIP, ES, HDAC1, NE, NSC, RA
55  2013 Targeted serum miRNA (TSmiR) test for diagnosis and follow-up of (testicular) germ cell cancer patients: a proof of principle. CH, GCC, SE, TE, TSmiR, YS
56  2013 Testicular teratomas: an intersection of pluripotency, differentiation and cancer biology. ES
57  2013 The action of all-trans-retinoic acid (ATRA) and synthetic retinoid analogues (EC19 and EC23) on human pluripotent stem cells differentiation investigated using single cell infrared microspectroscopy. ATRA, FTIR-MS
58  2013 Transforming pluripotency: an exon-level study of malignancy-specific transcripts in human embryonal carcinoma and embryonic stem cells. CSCs, ES, GCT
59  2012 A method for generating high-yield enriched neuronal cultures from P19 embryonal carcinoma cells. CNS, RA
60  2012 Acute hypersensitivity of pluripotent testicular cancer-derived embryonal carcinoma to low-dose 5-aza deoxycytidine is associated with global DNA Damage-associated p53 activation, anti-pluripotency and DNA demethylation. 5-Aza, ES, TGCTs
61  2012 Chemotherapeutic sensitivity of testicular germ cell tumors under hypoxic conditions is negatively regulated by SENP1-controlled sumoylation of OCT4. Su-OCT4, TGCT
62  2012 Feed-back regulation of disabled-2 (Dab2) p96 isoform for GATA-4 during differentiation of F9 cells. Dab2, ExE, RA
63  2012 Generation of Mouse STO Feeder Cell Lines That Confer Resistance to Several Types of Selective Drugs. ble, ES, hyg, iPS, neo, puro
64  2012 Human embryonic stem cells fail to activate CHK1 and commit to apoptosis in response to DNA replication stress. ESCs, ssDNA
65  2012 Lidamycin induces neural differentiation of mouse embryonic carcinoma cells through down-regulation of transcription factor Oct4. ChIP, ES
66  2012 Methylation profile of DNA repetitive elements in human testicular germ cell tumor. COBRA, TGCTs
67  2012 MicroRNA expression profiling of carcinoma in situ cells of the testis. CIS, miRNA, NS, SE
68  2012 Nanog regulates molecules involved in stemness and cell cycle-signaling pathway for maintenance of pluripotency of P19 embryonal carcinoma stem cells. CDK, ES, LIF, siRNA
69  2012 Reduced proficiency in homologous recombination underlies the high sensitivity of embryonal carcinoma testicular germ cell tumors to Cisplatin and poly (adp-ribose) polymerase inhibition. HR, ICL, PARP, TGCT
70  2012 Silencing of cancer-germline genes in human preimplantation embryos: evidence for active de novo DNA methylation in stem cells. CG
71  2012 Suppression of cancer stemness p21-regulating mRNA and microRNA signatures in recurrent ovarian cancer patient samples. CSCs, mEC, miRNA
72  2012 Transcription factors Sp1 and p73 control the expression of the proapoptotic protein NOXA in the response of testicular embryonal carcinoma cells to cisplatin. TGCTs
73  2012 UTF1 deficiency promotes retinoic acid-induced neuronal differentiation in P19 embryonal carcinoma cells. RA
74  2012 Vitamin D metabolism and effects on pluripotency genes and cell differentiation in testicular germ cell tumors in vitro and in vivo. CIS, TGCTs, VD, VDR
75  2011 3-Dimensional cell culture for on-chip differentiation of stem cells in embryoid body. EB, RA
76  2011 Ascl1/Mash1 is a novel target of Gli2 during Gli2-induced neurogenesis in P19 EC cells. bHLH, RA, Shh
77  2011 AW551984: a novel regulator of cardiomyogenesis in pluripotent embryonic cells. ---
78  2011 Dual roles of Oct4 in the maintenance of mouse P19 embryonal carcinoma cells: as negative regulator of Wnt/beta-catenin signaling and competence provider for Brachyury induction. ICM
79  2011 Effects of selegiline, a monoamine oxidase B inhibitor, on differentiation of P19 embryonal carcinoma stem cells, into neuron-like cells. MAO-B
80  2011 Embryonal carcinoma cell induction of miRNA and mRNA changes in co-cultured prostate stromal fibromuscular cells. miRNA
81  2011 Generation of pluripotent cancer-initiating cells from transformed bone marrow-derived cells. BMDCs, bmPCI, ES
82  2011 High-content screening for chemical modulators of embryonal carcinoma cell differentiation and survival. ES
83  2011 Inhibition of mouse embryonic carcinoma cell growth by lidamycin through down-regulation of embryonic stem cell-like genes Oct4, Sox2 and Myc. ADM, ES
84  2011 Interaction of Hand2 and E2a is important for transcription of Phox2b in sympathetic nervous system neuron differentiation. bHLH, SNS
85  2011 Mapping the stem cell state: eight novel human embryonic stem and embryonal carcinoma cell antibodies. ES
86  2011 Minimum regions of genomic imbalance in stage I testicular embryonal carcinoma and association of 22q loss with relapse. aCGH, NS, TGCT
87  2011 Mixed germ cell tumor with embryonal carcinoma, choriocarcinoma, and epithelioid trophoblastic tumor in the ovary of a cynomolgus monkey. CC, CK7, ETT
88  2011 Nuclear accumulation of an uncapped RNA produced by Drosha cleavage of a transcript encoding miR-10b and HOXD4. AP, IRES, kb, miR-10b, RARE
89  2011 Origins of Cdx1 regulatory elements suggest roles in vertebrate evolution. RA, RARE
90  2011 Origins of pluripotent stem cells. EpiSCs, ES, iPS
91  2011 p53 hypersensitivity is the predominant mechanism of the unique responsiveness of testicular germ cell tumor (TGCT) cells to cisplatin. TGCT
92  2011 Reprogramming mediated by cell fusion technology. ES
93  2011 Retinoic acid-treated pluripotent stem cells undergoing neurogenesis present increased aneuploidy and micronuclei formation. ES, iPS, NPCs, RA
94  2011 Role of oxidative stress and the mitochondrial permeability transition in methylmercury cytotoxicity. CsA, cyt c
95  2011 Selective proapoptotic activity of polyphenols from red wine on teratocarcinoma cell, a model of cancer stem-like cell. RWPs
96  2011 Serine/threonine kinase 17A is a novel p53 target gene and modulator of cisplatin toxicity and reactive oxygen species in testicular cancer cells. ---
97  2011 Sodium arsenite dependent protein expression analysis on human embryonic carcinoma (NCCIT) cell line. EBs, GRP78, HSP90, MALDI-TOF MS, TLR6, ULK3, VCP
98  2011 TCF3 inhibits F9 embryonal carcinoma growth by the down-regulation of Oct4. ES, TCF3
99  2011 The seminoma cell line TCam-2 is sensitive to HDAC inhibitor depsipeptide but tolerates various other chemotherapeutic drugs and loss of NANOG expression. GCT
100  2011 Zac1 is a histone acetylation-regulated NF-kappaB suppressor that mediates histone deacetylase inhibitor-induced apoptosis. HDAC, NF-kappaB