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Abbreviation : EE
Long Form : ethinyl estradiol
No. Year Title Co-occurring Abbreviation
2022 A novel estetrol-containing combined oral contraceptive: European expert panel review. COCs, DRSP
2022 Activation of natural killer T cells contributes to Th1 bias in the murine liver after 14 d of ethinylestradiol exposure. ICP, iNKT, OCs
2022 Bleeding Patterns of Oral Contraceptives with a Cyclic Dosing Regimen: An Overview. COCs, DRSP, OCs, POP
2022 Combined effects of the contraceptive hormones, ethinyl estradiol and levonorgestrel, on the use of place and response memory in gonadally-intact female rats. LNG
2022 Combined oral contraceptives containing estradiol valerate vs ethinylestradiol on coagulation: A randomized clinical trial. CI, EV
2022 Determination and Removal of Selected Pharmaceuticals and Total Organic Carbon from Surface Water by Aluminum Chlorohydrate Coagulant. ACH, AMO, COD, COL, DIC, DoE, ERY, FLX, RSM, TOC, TSS
2022 Effect of two combinations of low-dose oral contraceptives on adolescent bone mass: A clinical trial with 2 years follow-up. ---
2022 Effects of estradiol- and ethinylestradiol-based contraceptives on adrenal steroids: A randomized trial. CBG, COC, EV, FCI
2022 Estradiol Valerate vs Ethinylestradiol in Combined Oral Contraceptives: Effects on the Pituitary-Ovarian Axis. AMH, COCs, EV, FAI, FSH, SHBG
10  2022 Estrogen replacement therapy: effects of starting age on final height of girls with chronic kidney disease and short stature. CKD, FH, GH, MPH, PTH
11  2022 Ethinylestradiol in combined hormonal contraceptive has a broader effect on serum proteome compared with estradiol valerate: a randomized controlled trial. COC, DNG, EV
12  2022 Evaluating the Cognitive Impacts of Drospirenone, a Spironolactone-Derived Progestin, Independently and in Combination With Ethinyl Estradiol in Ovariectomized Adult Rats. GAD
13  2022 Evaluation of the potential for pharmacokinetic interaction between tirabrutinib and levonorgestrel/ethinyl estradiol in healthy female volunteers. CIs, GLSM, LEVO, TIRA
14  2022 Fostemsavir and ethinyl estradiol drug interaction: Clinical recommendations for co-administration. ARV, COCs, DDIs, NET
15  2022 Impact of pharmacological interventions on biochemical hyperandrogenemia in women with polycystic ovary syndrome: a systematic review and meta-analysis of randomised controlled trials. CPA, DHEAS, OCP, PCOS, PRISMA, RCTs, SHBG, vs
16  2022 iNKT17 cells play a pathogenic role in ethinylestradiol-induced cholestatic hepatotoxicity. IHC, iNKT
17  2022 Integrated Lipidomics and Metabolomics Study of Four Chemically Induced Mouse Models of Acute Intrahepatic Cholestasis. ANIT, DDC, LCA, PBC
18  2022 Maintaining bone health by estrogen therapy in patients with advanced prostate cancer: a narrative review. ADT, DES, LHRHa, PCa, tE2
19  2022 Multidrug Resistance-Associated Protein 2 Deficiency Aggravates Estrogen-Induced Impairment of Bile Acid Metabolomics in Rats. BAs, CAR, ICP, LC-MS, MRP2, MRP3, MRP4, WT
20  2022 Oral Contraceptive Steroids Promote Papillary Thyroid Cancer Metastasis by Targeting Angiogenesis and Epithelial-Mesenchymal Transition. EMT, LNG, PTC
21  2022 PF-PLC micelles ameliorate cholestatic liver injury via regulating TLR4/MyD88/NF-κB and PXR/CAR/UGT1A1 signaling pathways in EE-induced rats. PF, PF-PLC micelles
22  2022 Pharmacokinetic Interaction Between the MEK1/MEK2 Inhibitor Trametinib and Oral Contraceptives Containing Norethindrone and Ethinyl Estradiol in Female Patients With Solid Tumors. AUC, COCs, geo-mean, NE
23  2022 Ra-223 and Ethinylestradiol Combination Therapy in Castration-resistant Prostate Cancer. mCRPC
24  2022 Resveratrol modulates the gut microbiota of cholestasis in pregnant rats. ICP, KEGG, rRNA, UDCA
25  2022 Toxic Effects of Endocrine Disruptor Exposure on Collagen-Induced Arthritis. ATR, CIA, CII, CP, DEP, EDs, PFOS, VCZ
26  2022 Ziritaxestat Drug-Drug Interaction with Oral Contraceptives: Role of SULT1E1 Inhibition. AUClast, DDIs, DRSP
27  2021 A phase 1, open-label study to evaluate the drug interaction between islatravir (MK-8591) and the oral contraceptive levonorgestrel/ethinyl estradiol in healthy adult females. CIs, DDIs, GMRs, LNG
28  2021 Combined Oral Contraceptives and Venous Thromboembolism: Review and Perspective to Mitigate the Risk. APC, COCs, VTE
29  2021 Current and future hormonal contraception in Italy: results from an Italian consensus expert meeting. COC, NOMAC
30  2021 Determining the Exposure Threshold for Levonorgestrel Efficacy Using an Integrated Model Based Meta-Analysis Approach. BMI, DDIs, HCs, IRRs, LNG
31  2021 Effect of combined contraceptive pill on immune cell of ovarian endometriotic tissue. COCs, IQR
32  2021 Effect of environmental stressors on the mRNA expression of ecdysone cascade genes in Chironomus riparius. EcR, NP, USP
33  2021 Effect of oral contraceptives on total and bioavailable 25-hydroxyvitamin D. COCs, LNG, NETA, VDBP
34  2021 Effects of androgenic properties of progestin combined with ethinyl estradiol on vascular endothelial reactivity, plasma lipids and free radical production in women with endometriosis. ADMA, BAP, d-ROMs, DRSP, FMD, NET, SHBG
35  2021 Effects of Ethinyl Estradiol in Combined Oral Contraceptives on Cell Proliferation and Apoptosis in Ectopic Endometrial Tissue: A Randomized Controlled Study. COCs, DSG
36  2021 Endocrine and metabolic effects of an oral contraceptive containing estetrol and drospirenone. COC, DRSP, FSH, LH, LNG
37  2021 Estetrol: A New Choice for Contraception. COC, DRSP, ERalpha
38  2021 Health Status Is Affected, and Phase I/II Biotransformation Activity Altered in Young Women Using Oral Contraceptives Containing Drospirenone/Ethinyl Estradiol. COC, DRSP
39  2021 Kinsenoside Alleviates 17alpha-Ethinylestradiol-Induced Cholestatic Liver Injury in Rats by Inhibiting Inflammatory Responses and Regulating FXR-Mediated Bile Acid Homeostasis. BSEP, EIC, KD, NTCP
40  2021 Metabolic and laboratory effects of a progestin-only pill containing drospirenone 4 mg in comparison to desogestrel 75 g: a double-blind, double-dummy, prospective, randomised study. CHC, DRSP, DSG
41  2021 Natural and synthetic estrogens specifically alter nicotine demand and cue-induced nicotine seeking in female rats. ---
42  2021 Pharmacokinetic and Pharmacodynamic Profiles of Ethinylestradiol/Norgestimate Combination or Norethindrone upon Coadministration with Elagolix 150 mg Once Daily in Healthy Premenopausal Women. FSH, LH
43  2021 QbD Based Approach to Enhance the In-Vivo Bioavailability of Ethinyl Estradiol in Sprague-Dawley Rats. EENPs, QbD
44  2021 Randomized, double-blind, two-way crossover bioequivalence and adhesion study, in healthy women, of a transdermal contraceptive patch with a newly sourced adhesive component at the end of shelf life vs. the EVRA patch at the beginning of shelf life. BOSL, EMA, EOSL, GMRs, NGMN, PK, test
45  2021 Segesterone acetate serum levels with a regression model of continuous use of the segesterone acetate/ethinyl estradiol contraceptive vaginal system. CI, CVS, PK
46  2021 SERMs suppresses the growth of ERalpha positive cervical cancer xenografts through predominant inhibition of extra-nuclear ERalpha expression. CC, ER
47  2021 The effect of combined oral contraceptives containing drospirenone and ethinylestradiol on serum levels of amino acids and acylcarnitines. COCs, DRSP
48  2021 The new low-dose transdermal contraceptive system (Twirla): results from preclinical and Phase III trials. LNG, TDS
49  2021 Uterotrophic and in vitro screening for (anti)estrogenic activity of dipyrone. AA, canola oil, MAA
50  2020 A selective and highly sensitive high performance liquid chromatography with fluorescence derivatization approach based on Sonogashira coupling reaction for determination of ethinyl estradiol in river water samples. EDCs, HPLC
51  2020 Analysis and new contraception frontiers with combined vaginal rings. ---
52  2020 Burden of Menstrual Pain Measured by Heatmap Visualization of Daily Patient-Reported Data in Japanese Patients Treated with Ethinylestradiol/Drospirenone: A Randomized Controlled Study. DRSP
53  2020 Calculus Bovis Sativus up-regulates hepatic protein 2 (Mrp2) and Mrp4 in 17alpha-ethynylestradiol-induced cholestasis via a regulatory effect on ER signaling. ALP, AST, CBS, ERalpha, MRP2, TBIL
54  2020 Coenzyme Q 10 supplementation: A potential therapeutic option for the treatment of intrahepatic cholestasis of pregnancy. CoQ10, CoQ9, ICP, UDCA
55  2020 Confirmation of the drug-drug interaction potential between cobicistat-boosted antiretroviral regimens and hormonal contraceptives. ATV, COBI, DDI, DRV, PIs
56  2020 Efficacy, safety, and tolerability of a levonorgestrel/ethinyl estradiol transdermal delivery system: Phase 3 clinical trial results. BMI, LNG, PI, TDS
57  2020 Electrochemical study and simultaneous voltammetric determination of contraceptives ethinylestradiol and cyproterone acetate using silver nanoparticles solid amalgam electrode and cationic surfactant. CPA, SCV
58  2020 Elution from intact and broken vaginal contraceptive rings: an in vitro study. ETO, IVE
59  2020 Estradiol Valerate in COC Has More Favorable Inflammatory Profile Than Synthetic Ethinyl Estradiol: A Randomized Trial. COCs, DNG, EV, HDL, HDL, hs-CRP, LDL, PTX3
60  2020 Ethinyl estradiol vs estradiol valerate in combined oral contraceptives - Effect on glucose tolerance: A randomized, controlled clinical trial. AUC, COCs, DNG, EV, HOMA-IR, ISI, OGTT
61  2020 Ethinylestradiol and its effects on the macrophages in the prostate of adult and senile gerbils. ---
62  2020 Evaluation of different antiandrogenic progestins on clinical and biochemical variables in polycystic ovary syndrome. CMA, COC, DNG, DRSP, PCOS, SHBG
63  2020 Extended-cycle versus conventional treatment with a combined oral contraceptive containing ethinylestradiol (30 mug) and levonorgestrel (150 mug) in a randomized controlled trial. LNG
64  2020 Gonadotropin Glycoforms Circulating in Women Using Progestins of the Levonorgestrel Family for Contraception. FSHtri
65  2020 Hormonal Contraceptives and the Risk of Venous Thrombosis. COCs, VT
66  2020 Ibrutinib does not have clinically relevant interactions with oral contraceptives or substrates of CYP3A and CYP2B6. AUC, LN, OCs
67  2020 Lack of Drug-Drug Interaction Between Filgotinib, a Selective JAK1 Inhibitor, and Oral Hormonal Contraceptives Levonorgestrel/Ethinyl Estradiol in Healthy Volunteers. FIL, LEVO, PK
68  2020 Levonorgestrel vs combined oral contraceptive pills in treatment of female acne and hirsutism. GAGS, LNG, MFGS, OC
69  2020 Low-dose 17alpha-ethinyl estradiol (EE) exposure exacerbates lupus renal disease and modulates immune responses to TLR7/9 agonists in genetically autoimmune-prone mice. ---
70  2020 Mechanical and Physical Behavior of Fibrin Clot Formation and Lysis in Combined Oral Contraceptive Users. COCs, DRSP, PPP, TEG, VTE
71  2020 Multigenerational and transgenerational impact of paternal bisphenol A exposure on male fertility in a mouse model. BPA, F0-F1, NRF
72  2020 Norethisterone and its acetate - what's so special about them? NET
73  2020 Novel reversed-phase HPLC method for simultaneous determination of ethynodiol diacetate (EDA)/ethinyl estradiol (EE) in pharmaceutical dosage form. EDA
74  2020 Papillary Thyroid Cancer-Promoting Activities of Combined Oral Contraceptive Components. LD-COC, LNG, OCPs, PTC, qRT-PCR
75  2020 Protective impact of lycopene on ethinylestradiol-induced cholestasis in rats. ---
76  2020 Quantitative Assessment of Levonorgestrel Binding Partner Interplay and Drug-Drug Interactions Using Physiologically Based Pharmacokinetic Modeling. BMI, DDIs, LNG, PBPK
77  2020 Risk of sexual dysfunction with progestin-based contraceptives in women of child-bearing age. COC, IUD, SD
78  2020 Safety, efficacy and quality of life of the novel vaginal contraceptive ring containing etonogestrel/ethinylestradiol 11.0/3.474 mg after 3 years of "real life" experience. CVR, ETO, QoL
79  2020 Serum Metabolome Changes in Relation to Prothrombotic State Induced by Combined Oral Contraceptives with Drospirenone and Ethinylestradiol. COCs, DRSP
80  2020 The effect of type of oral contraceptive pill and duration of use on fresh and cumulative live birth rates in IVF/ICSI cycles. CLBR, COS, OCP
81  2020 The effects of 28-day early-life exposure to triphenyl phosphate (TPhP) on odor preference and sexual behavior in female rats. TPHP
82  2020 Therapeutic Effect of Ethinylestradiol in Castration-resistant Prostate Cancer. CRPC, PSA
83  2019 Altered pharmacokinetics of combined oral contraceptives in obesity - multistudy assessment. BMI, BSA, CL, COCs, LNG, PKs
84  2019 Biosorption of 17alpha-ethinylestradiol by yeast biomass from ethanol industry in the presence of estrone. BD, EST, HC, IS, YB
85  2019 Birth Control Pills and Thrombotic Risks: Differences of Contraception Methods with and without Estrogen. COCs, VTE
86  2019 Bleeding profile associated with 1-year use of the segesterone acetate/ethinyl estradiol contraceptive vaginal system: pooled analysis from Phase 3 trials. aOR, B/S, CI, CVS, SA
87  2019 Calculus Bovis Sativus Improves Bile Acid Homeostasis via Farnesoid X Receptor-Mediated Signaling in Rats With Estrogen-Induced Cholestasis. BA, CBS, FXR
88  2019 CLARITY-BPA: Bisphenol A or Propylthiouracil on Thyroid Function and Effects in the Developing Male and Female Rat Brain. BPA, BW, PND, PTU
89  2019 Combined oral contraceptive in female mice causes hyperinsulinemia due to beta-cell hypersecretion and reduction in insulin clearance. COC, CTL, DRSP
90  2019 Comparative pharmacokinetic estimates of drospirenone alone and in combination with ethinyl estradiol after single and repeated oral administration in healthy females. AUC, DRSP, PK
91  2019 Comparative randomized study on the sexual function and quality of life of women on contraceptive vaginal ring containing ethinylestradiol/etonogestrel 3.47/11.00mg or 2.7/11.7mg. CVR, ENG, FSDS, FSFI, QoL
92  2019 Comparison of change in body weight between contraception containing 30-mug ethinylestradiol/2-mg chlormadinone acetate or 30-mug ethinylestradiol/3-mg drospirenone: a randomised controlled trial. CMA, COC, DRSP
93  2019 Effects of ritonavir-boosted protease inhibitors on combined oral contraceptive pharmacokinetics and pharmacodynamics in HIV-positive women. AUC, COC, LNG
94  2019 Evaluating the oestrogenic activities of aqueous root extract of Asparagus africanus Lam in female Sprague-Dawley rats and its phytochemical screening using Gas Chromatography-Mass Spectrometry (GC/MS). Calb3, ERalpha, GC/MS, ORA
95  2019 Gene expression profiling of cultured mouse testis fragments treated with ethinylestradiol. Cyp26b1, IL16, PND, qPCR
96  2019 Hepatoprotection of auraptene from the peels of citrus fruits against 17alpha-ethinylestradiol-induced cholestasis in mice by activating farnesoid X receptor. FXR
97  2019 Hormonal contraception in women with endometriosis: a systematic review. CHCs, COCs, NETA, POCs, POPs, QoL
98  2019 In vitro activity of steroidal dendrimers on Trypanosoma cruzi epimastigote form with PAMAM dendrons modified by "click" chemistry. BZ
99  2019 Influence of Oral Contraceptive Use on Adaptations to Resistance Training. CSA, MRI, OCs, RM
100  2019 Metabolomics-based pathway changes in testis fragments treated with ethinylestradiol in vitro. arginine and spermine, LC/MS